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Search Results: 1 - 10 of 25024 matches for " Eduardo; Grá Oramas "
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Influencia de factores epidemiológicos en la progresión de la fibrosis en la hepatitis crónica C
Vilar Gómez,Eduardo; Grá Oramas,Bienvenido; Llanio Navarro,Raimundo; Arús Soler,Enrique;
Revista Cubana de Medicina , 2003,
Abstract: approximately 80 % of hepatitis c evolves to chronicity. the epidemiological and viral factors as well as those of the guest take part in the progression of the disease. the behavior of the epidemiological variables associated with chronic hepatitis c was described and the possible association of these ones with the intensity of fibrosis was identified. 80 patients with hepatitis c were studied and the intensity of fibrosis was determined by the metavir scoring system. they were grouped into absence or little fibrosis (f0-f1) and marked fibrosis (f2-f4) seeking for the possible statistical association with the epidemiological factors. a significant association was found among the infection's oldness estimate, the way it was acquired, the patient's age on catching it and the intensity of fibrosis. the progression of hepatits c may be determined by some epidemiological factors influencing decisively the natural history of the disease.
Bases fisiopatológicas de la insuficiencia hepática aguda
Vilar Gómez,Eduardo; Grá Oramas,Bienvenido; Llanio Navarro,Raimundo; Arús Soler,Enrique;
Revista Cubana de Medicina , 2004,
Abstract: a review was made to explain how the diverse cellular processes occurring in the severely damaged liver tissue and in the mesenteric circulation influence on the different systemic alterations appearing in acute liver failure, and the close relation existing among them. the acute liver failure is a clinical syndrome resulting from a mass liver necrosis generating progressive dysfunction of the organ with the presence of deep alterations in its detoxicating, metabolic, sinthesizing and excreting functions.the hypothesis of critical mass, as well as that on endotoxins-cytokines and vasoactive substances explain somehow the different molecular changes supporting the physiopathological bases of this complex entity.
Influencia de factores epidemiológicos en la progresión de la fibrosis en la hepatitis crónica C
Eduardo Vilar Gómez,Bienvenido Grá Oramas,Raimundo Llanio Navarro,Enrique Arús Soler
Revista Cubana de Medicina , 2003,
Abstract: Aproximadamente 80 % de la hepatitis C evoluciona a la cronicidad. Factores como los epidemiológicos, virales y del huésped intervienen en la progresión de la enfermedad. Se describió el comportamiento de variables epidemiológicas asociadas a la hepatitis crónica C y se identificó la posible asociación de estas con la intensidad de la fibrosis. Se estudiaron 80 pacientes con hepatitis C. Se determinó la intensidad de la fibrosis por el sistema de puntuación METAVIR. Se agruparon en: ausencia o poca fibrosis (F0-F1) y fibrosis marcada (F2 a F4) buscando la posible asociación estadística con los factores epidemiológicos. Se halló asociación significativa entre el estimado de antigüedad de la infección, la vía de adquisición y la edad al contraerla con la intensidad de la fibrosis. La progresión de la hepatitis C puede estar determinada por algunos factores epidemiológicos que influyen de forma decisiva en la historia natural de la enfermedad. Approximately 80 % of hepatitis C evolves to chronicity. The epidemiological and viral factors as well as those of the guest take part in the progression of the disease. The behavior of the epidemiological variables associated with chronic hepatitis C was described and the possible association of these ones with the intensity of fibrosis was identified. 80 patients with hepatitis C were studied and the intensity of fibrosis was determined by the METAVIR scoring system. They were grouped into absence or little fibrosis (f0-F1) and marked fibrosis (F2-F4) seeking for the possible statistical association with the epidemiological factors. A significant association was found among the infection's oldness estimate, the way it was acquired, the patient's age on catching it and the intensity of fibrosis. The progression of hepatits C may be determined by some epidemiological factors influencing decisively the natural history of the disease.
Bases fisiopatológicas de la insuficiencia hepática aguda Physiopathological bases of acute liver failure
Eduardo Vilar Gómez,Bienvenido Grá Oramas,Raimundo Llanio Navarro,Enrique Arús Soler
Revista Cubana de Medicina , 2004,
Abstract: Se hace una revisión para explicar cómo influyen y la estrecha relación que tienen los diversos procesos celulares que ocurren en el tejido hepático, severamente da ado, y en la circulación mesentérica con las distintas alteraciones sistémicas que aparecen en la insuficiencia hepática aguda, síndrome clínico resultado de una necrosis hepática masiva que genera disfunción progresiva del órgano con la presencia de profundas alteraciones en sus funciones detoxificadora, metabólica, sintetizadora y excretora. La hipótesis de la masa crítica, así como la de las endotoxinas-citoquinas y sustancias vasoactivas explican de cierta forma los diferentes cambios moleculares que sustentan las bases fisiopatológicas de esta compleja entidad. A review was made to explain how the diverse cellular processes occurring in the severely damaged liver tissue and in the mesenteric circulation influence on the different systemic alterations appearing in acute liver failure, and the close relation existing among them. The acute liver failure is a clinical syndrome resulting from a mass liver necrosis generating progressive dysfunction of the organ with the presence of deep alterations in its detoxicating, metabolic, sinthesizing and excreting functions.The hypothesis of critical mass, as well as that on endotoxins-cytokines and vasoactive substances explain somehow the different molecular changes supporting the physiopathological bases of this complex entity.
The fall of the Gods, or modernity without illusions
Grüner,Eduardo;
Sociedad (Buenos Aires) , 2006,
Abstract: in this paper, the author explores the survival of religion in the world after the modern historical process known as "disillusionment with the world". in that context, the paper poses questions about the present relations between religion and the social sciences, bearing in mind religion?s ideological plasticity. an interest in various sociological traditions that have dealt with religious issues reveals that a purely rational approach to the problem is bound to frustrate hermeneutic power. perhaps what is being called into question is man?s "presence" in the world.
Hallazgos clínicos, bioquímicos y morfológicos en 103 pacientes con anticuerpos contra el virus de la hepatitis C
Infante Velázquez,Mirtha; Arús Soler,Enrique; Fernández Naranjo,Anayda; Grá Oramas,Bienvenido;
Revista Cubana de Medicina , 1998,
Abstract: 103 patients carriers of hepatitis c virus antibodies detected by the cuban diagnostic system (anti hcv, cigb, havana) were studied. active chronic hepatitis (23.2 %) was the predominant histological lesion, although there were 2 cases with acute severe hepatitis due to a combined infection with a and b viruses. a few symptoms were observed in most of the patients, who were blood donors and blood transfusion receptors (44.5 %). the latter were associated with the most severe hapatic lesions. it is stressed the presence of heal thy carriers of the virus.
Hallazgos clínicos, bioquímicos y morfológicos en 103 pacientes con anticuerpos contra el virus de la hepatitis C
Mirtha Infante Velázquez,Enrique Arús Soler,Anayda Fernández Naranjo,Bienvenido Grá Oramas
Revista Cubana de Medicina , 1998,
Abstract: Se estudiaron 103 pacientes portadores de anticuerpos contra el virus de la hepatitis C detectado mediante el empleo del sistema diagnóstico cubano (Anti VHC, CIGB, La Habana). La lesión histológica predominante fue la hepatitis crónica activa (23,2 %), aunque se presentaron 2 casos con hepatitis aguda grave por infección combinada con los virus A y B. En muchos de los enfermos la afección cursó con escasos síntomas. La mayoría de los pacientes eran donantes de sangre y receptores de transfusiones (44,5 %). Estos últimos se relacionaron con las lesiones hepáticas más severas. Se se aló la presencia de portadores sanos del virus. 103 patients carriers of hepatitis C virus antibodies detected by the Cuban diagnostic system (Anti HCV, CIGB, Havana) were studied. Active chronic hepatitis (23.2 %) was the predominant histological lesion, although there were 2 cases with acute severe hepatitis due to a combined infection with A and B viruses. A few symptoms were observed in most of the patients, who were blood donors and blood transfusion receptors (44.5 %). The latter were associated with the most severe hapatic lesions. It is stressed the presence of heal thy carriers of the virus.
Interferón alfa 2b recombinante más ribavirina en el tratamiento de la hepatitis crónica C
Sánchez Rodríguez,Yoan Antonio; Arús Soler,Enrique; Grá Oramas,Bienvenido; López Saura,Pedro; Nodarse Cuní,Hugo;
Revista Cubana de Medicina , 2010,
Abstract: the hepatitis c virus becomes in leading cause of chronic hepatitis, hepatic cirrhosis, hepatocarcinoma and liver transplant at world level. objective: the aim of present study is to determine the virological, biochemical and histological course of patients presenting with chronic hepatitis c under a combination of recombinant interferon alfa-2b plus ribavirin and to identify the main factors associated with the rates obtained of virological response. methods: a non-controlled and multicenter phase iv clinical-therapeutical trial was sponsored by the institute of gastroenterology and the genetics and biotechnology engineering center from may, 2002 to may, 2006. sample included 122 patients diagnosed with chronic hepatitis c fulfilling the predetermined inclusion and exclusion criteria. recombinant interferon alfa-2b (3 millions of t.i.d units) was used plus ribavirin (1000 or 1200 mg daily depending on the body weight) during 48 weeks. results: we achieved a sustained biochemical and virological response rate of 32.8 and 50.8 %, respectively at week 72. a 41.3,% from the total of patients had a histological improvement at the expense of reduction of fibrosis and a few changes in inflammation level. conclusions: raking into account the global response rate achieved this combined treatment was considered effectiveness for chronic hepatitis c and we recommended to deepen in the knowledge of infection in cuba, as well as in more efficient treatment options for this disease.
Interferón alfa 2b recombinante más ribavirina en el tratamiento de la hepatitis crónica C Recombinant Interferon alfa-2b plus Ribavirin in treatment of chronic hepatitis C
Yoan Antonio Sánchez Rodríguez,Enrique Arús Soler,Bienvenido Grá Oramas,Pedro López Saura
Revista Cubana de Medicina , 2010,
Abstract: El virus de la hepatitis C se ha convertido en la causa principal de hepatitis crónica, cirrosis hepática, hepatocarcinoma, y trasplante de hígado a nivel mundial. OBJETIVO: El presente estudio estuvo dirigido a determinar la evolución virológica, bioquímica e histológica de los pacientes con hepatitis crónica C bajo terapia combinada Interferón a 2b recombinante más ribavirina e identifica los principales factores asociados a las tasas obtenidas de respuesta virológica sostenida. MéTODOS: Ensayo clínico-terapéutico fase IV, abierto, no controlado y multicéntrico rectorado por el Instituto de Gastroenterología y el Centro de Ingeniería Genética y Biotecnología en el período comprendido de mayo de 2001 a mayo de 2006. La muestra estuvo conformada por 122 pacientes con hepatitis crónica C que cumplieron con criterios de inclusión y exclusión predeterminados. Se utilizó interferón a 2b recombinante (3 millones de unidades 3 veces por semana) más ribavirina (1 000 o 1 200 mg diarios en dependencia del peso corporal) durante 48 sem. RESULTADOS: Se obtuvo una tasa de respuesta virológica y bioquímica sostenida a la semana 72 de 32,8 y 50,8 % respectivamente. Un 41,3 % del total de pacientes experimentó mejoría histológica a expensas de la reducción de la fibrosis y pocos cambios en la inflamación. CONCLUSIONES: Teniendo en cuenta la tasa de respuesta global obtenida, se consideró como tratamiento eficaz para la hepatitis crónica C y se recomendó profundizar en el conocimiento de las características de la infección en Cuba así como en opciones de tratamiento más eficaces para esta enfermedad. The hepatitis C virus becomes in leading cause of chronic hepatitis, hepatic cirrhosis, hepatocarcinoma and liver transplant at world level. OBJECTIVE: The aim of present study is to determine the virological, biochemical and histological course of patients presenting with Chronic hepatitis C under a combination of recombinant Interferon alfa-2b plus Ribavirin and to identify the main factors associated with the rates obtained of virological response. METHODS: A non-controlled and multicenter phase IV clinical-therapeutical trial was sponsored by the Institute of Gastroenterology and the Genetics and Biotechnology Engineering Center from May, 2002 to May, 2006. Sample included 122 patients diagnosed with chronic hepatitis C fulfilling the predetermined inclusion and exclusion criteria. Recombinant Interferon alfa-2b (3 millions of t.i.d units) was used plus Ribavirin (1000 or 1200 mg daily depending on the body weight) during 48 weeks. RESULTS: We achieved a sustained bio
Rentabilidad del engorde a corral de bovinos de carne en la provincia de Mendoza, Argentina
Grünwaldt,Eduardo Guillermo; Guevara,Juan Carlos;
Revista de la Facultad de Ciencias Agrarias. Universidad Nacional de Cuyo , 2011,
Abstract: feedlot profitability was determined under different production and economic scenarios for cattle prices in 2009 and 2010. the basic data came from surveys in feedlots, interviews with key informants and bibliographical consult. internal rate of return and net present value were estimated considering 12% as annual capital opportunity cost. total capital varied in relation to total purchase or partial production of food. the incomes from 3,000 animals year-1 increased by 50% in the year 2010 compared to 2009. in the year 2009, without compensations, there was no profitability when the foods for cattle were purchased. with 5, 10 and 15% increases in investments and operating costs, profitability was attained with 4,466, 6,214 and 9,670 animals year-1, respectively, when the foods were purchased, and with 2,110, 2,430 and 2,880 animals year-1, respectively, when the foods were produced. cattle prices for 2010 compared to those of 2009 increased profitability without compensations using either purchased or produced food. for reaching profitability in year 2010, a total of 2,300 and 1,500 animals year-1 were necessary when the foods were purchased or produced, respectively. the hypothesis that profitability depends on production scale associated with the considered scenarios was verified.
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