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Search Results: 1 - 10 of 565485 matches for " Eddie C. M. Hui "
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Differential games of partial information forward-backward doubly stochastic differential equations and applications
Eddie C. M. Hui,Hua Xiao
Mathematics , 2011,
Abstract: This paper is concerned with a new type of differential game problems of forwardbackward stochastic systems. There are three distinguishing features: Firstly, our game systems are forward-backward doubly stochastic differential equations, which is a class of more general game systems than other forward-backward stochastic game systems without doubly stochastic terms; Secondly, forward equations are directly related to backward equations at initial time, not terminal time; Thirdly, the admissible control is required to be adapted to a sub-information of the full information generated by the underlying Brownian motions. We give a necessary and a sufficient conditions for both an equilibrium point of nonzero-sum games and a saddle point of zero-sum games. Finally, we work out an example of linear-quadratic nonzero-sum differential games to illustrate the theoretical applications. Applying some stochastic filtering techniques, we obtain the explicit expression of the equilibrium point.
Self-Construal and Subjective Wellbeing in Two Ethnic Communities in Singapore  [PDF]
Weining C. Chang, Mohd Maliki bin Osman, Eddie M. W. Tong, Daphne Tan
Psychology (PSYCH) , 2011, DOI: 10.4236/psych.2011.22011
Abstract: The study reported here addressed two questions concerning the applicability to other collectivist cultures of a model developed on the basis of socially defined self-construals and their consequences for subjective wellbeing (Kwan, Bond, & Singelis, 1997). In contrast to the social centrality of the Singaporean Chinese, Islam enjoys centrality in the Malay community. Is subjective well-being in these two cultures attributable to independent or interdependent self-construal? Do parallel paths to subjective wellbeing originate from these two forms of self-construal? Are the respective mediators, self-esteem and relationship harmony, functioning in the same way in these different communities? Two hundred and eighty-six participants (121 Malays, including 49 females and 72 males, and 165 Chinese, including 62 males and 103 females, average age, 18.52) were drawn from three tertiary technical training institutes in Singapore. Independent and interdependent self-construal, Rosenberg’s Self-esteem Scale (SE), the Relationship Harmony Scale (RH) (Kwan, et al. 1997) and the Satisfaction with Life Scale (SL) (Diener, Emmons. Larsen, & Griffins, 1985) were administered to test the model. For the Chinese, the best-fit model required a path between the two forms of self-construal, confirming their overlapping nature. For the Malays, a radically different model fits the data: relationship harmony no longer functions as a mediator but as an independent contributor in its own right. These results raise questions about the meaning and consequences of socially defined self-construal in different collectivist cultures, and the path between ¬the self and subjective wellbeing.
Evidence for AGN Feedback in the Broad Absorption Lines and Reddening of Mrk 231
Karen M. Leighly,Donald M. Terndrup,Eddie Baron,Adrian B. Lucy,Matthias Dietrich,Sarah C. Gallagher
Physics , 2014,
Abstract: We present the first J-band spectrum of Mrk 231, which reveals a large \ion{He}{1}*$\lambda 10830$ broad absorption line with a profile similar to that of the well-known \ion{Na}{1} broad absorption line. Combining this spectrum with optical and UV spectra from the literature, we show that the unusual reddening noted by \citet{veilleux13} is explained by a reddening curve like those previously used to explain low values of total-to-selective extinction in SNe Ia. The nuclear starburst may be the origin and location of the dust. Spatially-resolved emission in the broad absorption line trough suggests nearly full coverage of the continuum emission region. The broad absorption lines reveal higher velocities in the \ion{He}{1}* lines (produced in the quasar-photoionized \ion{H}{2} region) compared with the \ion{Na}{1} and \ion{Ca}{2} lines (produced in the corresponding partially-ionized zone). {\it Cloudy} simulations show that a density increase is required between the \ion{H}{2} and partially-ionized zones to produce ionic column densities consistent with the optical and IR absorption line measurements and limits, and that the absorber lies $\sim 100\rm \, pc$ from the central engine. These results suggest that the \ion{He}{1}* lines are produced in an ordinary quasar BAL wind that impacts upon, compresses, and accelerates the nuclear starburst's dusty effluent (feedback in action), and the \ion{Ca}{2} and \ion{Na}{1} lines are produced in this dusty accelerated gas. This unusual circumstance explains the rarity of \ion{Na}{1} absorption lines; without the compression along our line of sight, Mrk~231 would appear as an ordinary FeLoBAL.
Bounded Model Checking of C++ Programs Based on the Qt Framework (extended version)
Felipe R. M. Sousa,Lucas C. Cordeiro,Eddie B. de Lima Filho
Computer Science , 2015,
Abstract: The software development process for embedded systems is getting faster and faster, which generally incurs an increase in the associated complexity. As a consequence, consumer electronics companies usually invest a lot of resources in fast and automatic verification processes, in order to create robust systems and reduce product recall rates. Because of that, the present paper proposes a simplified version of the Qt framework, which is integrated into the Efficient SMT-Based Bounded Model Checking tool to verify actual applications that use the mentioned framework. The method proposed in this paper presents a success rate of 94.45%, for the developed test suite.
Adaptation and Immunity
Eddie C. Holmes
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0020307
Adaptation and Immunity
Eddie C Holmes
PLOS Biology , 2004, DOI: 10.1371/journal.pbio.0020307
Peripheral Helper Lymphocytes Produce Interleukin 12 in Cancer Patients
Márcia A. Michelin, Douglas R. Abdalla, André A.R. Aleixo and Eddie F.C. Murta
Clinical Medicine Insights: Oncology , 2012, DOI: 10.4137/CMO.S11292
Abstract: The aim of the study was to seek evidence for the production of IL-12 by CD4+ T lymphocytes in in vitro and ex vivo trials. We performed in vitro trials with spleen cells from mice subjected to carcinogenesis, as well as ex vivo trials with cells obtained from the peripheral blood of healthy individuals and cancer patients. We were able to verify a significantly increased expression of IL-12 in CD4+ T lymphocytes from mice and patients with tumors, compared to controls. Follow-up studies are needed to clarify whether this difference is related to being in a chronic disease state or whether it is an attempt by the immune system to produce an anti-tumor response, since T lymphocytes from healthy donors were not able to produce IL-12 when in contact with polyclonal stimuli. We concluded that, in cancer, T helper cells are capable of synthesizing IL-12, raising the question of whether we are faced with another profile, Th12.
Peripheral Helper Lymphocytes Produce Interleukin 12 in Cancer Patients
Márcia A. Michelin,Douglas R. Abdalla,André A.R. Aleixo,Eddie F.C. Murta
Clinical Medicine Insights: Oncology , 2013,
VERITAS observations of M87 from 2007 to present
C. M. Hui,for the VERITAS collaboration
Physics , 2009,
Abstract: M87 is a nearby radio galaxy and because of its misaligned jet, it is possible to correlate detailed spatially-resolved emission regions in the radio, optical to X-ray waveband with unresolved but contemporaneous flux measurements in the TeV regime. Hence, M87 provides a unique opportunity to reveal the emission mechanisms responsible for high energy gamma-ray emission from active galactic nuclei. Observations with VERITAS since 2007 have resulted in 90 hours of data while 2008 observations were part of a concerted effort involving the three major atmospheric Cherenkov observatories: H.E.S.S., MAGIC and VERITAS. As a result of the TeV campaign, a high flux state of M87 was detected in February 2008 showing multiple flares with rapid variability. We will present the comprehensive results from VERITAS observations since 2007 and also show preliminary results from the 2009 campaign.
The Role of Selection in Shaping Diversity of Natural M. tuberculosis Populations
Caitlin S. Pepperell ,Amanda M. Casto,Andrew Kitchen,Julie M. Granka,Omar E. Cornejo,Eddie C. Holmes,Bruce Birren,James Galagan,Marcus W. Feldman
PLOS Pathogens , 2013, DOI: 10.1371/journal.ppat.1003543
Abstract: Mycobacterium tuberculosis (M.tb), the cause of tuberculosis (TB), is estimated to infect a new host every second. While analyses of genetic data from natural populations of M.tb have emphasized the role of genetic drift in shaping patterns of diversity, the influence of natural selection on this successful pathogen is less well understood. We investigated the effects of natural selection on patterns of diversity in 63 globally extant genomes of M.tb and related pathogenic mycobacteria. We found evidence of strong purifying selection, with an estimated genome-wide selection coefficient equal to ?9.5×10?4 (95% CI ?1.1×10?3 to ?6.8×10?4); this is several orders of magnitude higher than recent estimates for eukaryotic and prokaryotic organisms. We also identified different patterns of variation across categories of gene function. Genes involved in transport and metabolism of inorganic ions exhibited very low levels of non-synonymous polymorphism, equivalent to categories under strong purifying selection (essential and translation-associated genes). The highest levels of non-synonymous variation were seen in a group of transporter genes, likely due to either diversifying selection or local selective sweeps. In addition to selection, we identified other important influences on M.tb genetic diversity, such as a 25-fold expansion of global M.tb populations coincident with explosive growth in human populations (estimated timing 1684 C.E., 95% CI 1620–1713 C.E.). These results emphasize the parallel demographic histories of this obligate pathogen and its human host, and suggest that the dominant effect of selection on M.tb is removal of novel variants, with exceptions in an interesting group of genes involved in transportation and defense. We speculate that the hostile environment within a host imposes strict demands on M.tb physiology, and thus a substantial fitness cost for most new mutations. In this respect, obligate bacterial pathogens may differ from other host-associated microbes such as symbionts.
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