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Search Results: 1 - 6 of 6 matches for " Ebada "
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Bioactive Sesterterpenes and Triterpenes from Marine Sponges: Occurrence and Pharmacological Significance
Sherif S. Ebada,WenHan Lin,Peter Proksch
Marine Drugs , 2010, DOI: 10.3390/md8020313
Abstract: Marine ecosystems (>70% of the planet's surface) comprise a continuous resource of immeasurable biological activities and immense chemical entities. This diversity has provided a unique source of chemical compounds with potential bioactivities that could lead to potential new drug candidates. Many marine-living organisms are soft bodied and/or sessile. Consequently, they have developed toxic secondary metabolites or obtained them from microorganisms to defend themselves against predators [1]. For the last 30–40 years, marine invertebrates have been an attractive research topic for scientists all over the world. A relatively small number of marine plants, animals and microbes have yielded more than 15,000 natural products including numerous compounds with potential pharmaceutical potential. Some of these have already been launched on the pharmaceutical market such as Prialt ? (ziconotide; potent analgesic) and Yondelis ? (trabectedin or ET-743; antitumor) while others have entered clinical trials, e.g., alpidin and kahalalide F. Amongst the vast array of marine natural products, the terpenoids are one of the more commonly reported and discovered to date. Sesterterpenoids (C 25) and triterpenoids (C 30) are of frequent occurrence, particularly in marine sponges, and they show prominent bioactivities. In this review, we survey sesterterpenoids and triterpenoids obtained from marine sponges and highlight their bioactivities.
Plasma lipids and prothrombin time in rats fed palm oil and other commonly used fats in Egypt
Hussein, Mona M.,Salama, Fawzy M.,Ebada, Karina M.
Grasas y Aceites , 1993,
Abstract: Sprague-Dawley rats were fed for a total period of 8 weeks on six diets that were different in the source of their fat content. The fat content was provided either, palm oil or palm olein or corn oil or hydrogenated fat, or frying palm oil and mixture of corn oil + hydrogenated fat in the ratio (1:1). The latter was given to the control group. Animals fed these various experimental diets showed statistically significant differences in serum cholesterol and serum triglycerides content among all group. Increased HDL-cholesterol content was evident in animals fed on palm-olein and palm oil. The frying oil fed group showed lowest HDL-cholesterol content. In these experiments palm olein fed animals showed highest ratio of HDL-cholesterol to total cholesterol while the lowest ratio was shown in rats fed on frying oil. Prothrombin (PT) and activated partial thromboplastin time (PTT) showed higher values In palm oil, palm olein and corn oil diets as compared to all groups with each other. Ratas Sprague-Dawley fueron alimentadas durante un periodo total de 8 semanas con seis dietas diferentes en su contenido graso. El contenido graso fue proporcionado por aceite de palma u oleína de palma o aceite de maíz o grasa hidrogenada o aceite de palma de fritura y mezcla de aceite de maíz + grasa hidrogenada en la relación (1:1). El último fue dado al grupo de control. Los animales alimentados con las diferentes dietas experimentales mostraron diferencias significativas estadísticamente en el contenido en colesterol y triglicéridos en suero entre todos los grupos. El aumento en contenido HDL-colesterol fue evidente en animales alimentados con oleína de palma y aceite de palma. El grupo alimentado con aceite de fritura mostró el más bajo contenido en HDL-colesterol. En estos experimentos, los animales alimentados con oleína de palma mostraron la mayor relación de HDL-colesterol a colesterol total, mientras que la relación más baja fue mostrada en ratas alimentadas con aceite de fritura. El tiempo de protrombina (PT) y tromboplastina parcialmente activada (PTT) mostró valores elevados en dietas de aceite de palma, oleína de palma y aceite de maíz al comparar estos grupos con los demás.
Handsets Malware Threats and Facing Techniques
Marwa M. A. Elfattah,Aliaa A. A. Youssif,Ebada Sarhan
Computer Science , 2012,
Abstract: Nowadays, mobile handsets combine the functionality of mobile phones and PDAs. Unfortunately, mobile handsets development process has been driven by market demand, focusing on new features and neglecting security. So, it is imperative to study the existing challenges that facing the mobile handsets threat containment process, and the different techniques and methodologies that used to face those challenges and contain the mobile handsets malwares. This paper also presents a new approach to group the different malware containment systems according to their typologies.
Two New Jaspamide Derivatives from the Marine Sponge Jaspis splendens
Sherif S. Ebada,Victor Wray,Nicole J. De Voogd,Zhiwei Deng,Wenhan Lin,Peter Proksch
Marine Drugs , 2009, DOI: 10.3390/md7030435
Abstract: Two new jaspamide derivatives 2 and 3, together with the parent compound jaspamide (1) have been isolated from the marine sponge Jaspis splendens collected in Kalimantan (Indonesia). The structures of the new compounds were unambiguously elucidated based on 1D and 2D NMR spectral data, mass spectrometry and comparison with jaspamide (1). The new derivatives inhibited the growth of mouse lymphoma (L5178Y) cell line in vitro with IC50 values of <0.1 μg/mL.
Handsets Malware Threats and Facing Techniques
Marwa M. A. Elfattah,Aliaa A.A Youssif,,Ebada Sarhan Ahmed
International Journal of Advanced Computer Sciences and Applications , 2011,
Abstract: Nowadays, mobile handsets combine the functionality of mobile phones and PDAs. Unfortunately, mobile handsets development process has been driven by market demand, focusing on new features and neglecting security. So, it is imperative to study the existing challenges that facing the mobile handsets threat containment process, and the different techniques and methodologies that used to face those challenges and contain the mobile handsets malwares. This paper also presents a new approach to group the different malware containment systems according to their typologies.
Handset Malwares Threats Feature Extraction Based on Behavior Analysis
Marwa M. A. Efattah,Aliaa A. A. Youssif,Ebada Sarhan Ahmed
Computer and Information Science , 2012, DOI: 10.5539/cis.v5n2p79
Abstract: The malware threat for mobile phones is expected to increase with the great functionality enhancement of mobile phones. Despite the nowadays malware high abilities, there are a lot of challenges that facing the mobile threat containment process. From this perspective, this work introduces a novel effective solution for discovering handset malwares threats. The work proposed a new behavior based technique for mobile application analysis, which is based on exploiting the application DLL usages, in order to extract values that can be used in a malware detection process. The technique is highly expected to be able to detect zero day viruses that have the similar functionalities as existing ones. Also, since these DLL functions are easy to be extracted from the executable files, the approach is computationally efficient.
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