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Search Results: 1 - 10 of 408 matches for " ERTUGRUL FILIZ "
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In Silico chloroplast SSRs mining of Olea species
Biodiversitas , 2012,
Abstract: Filiz E, Koc E. 2012. In Silico chloroplast SSRs mining of Olea species. Biodiversitas 13: 114-117. Simple sequence repeat (SSR) markers are highly informative and have been widely applied as molecular markers in genetic studies. The purpose of present study is to analyze the occurrence and distribution of chloroplast SSRs in genic and intergenic regions from Olea species viz., Olea europaea, Olea europaea subsp. cuspidate, Olea europaea subsp. europaea, Olea europaea subsp. maroccana, Olea woodiana subsp. woodiana by using bioinformatics tools. We identified 1149 chloroplast SSRs (cpSSRs) in all genome and a total of 340 (29.6%) was located in genic regions. It was observed that the most abundant repeat types were found mononucleotide SSR (66.7 %) followed by trinucleotide SSR (28.3 %), dinucleotide (2.7%), tetranucleotide (1.5%) and pentanucleotide (0.8%). cpSSRs located in genic regions were identified only mono- and trinucleotide motifs, the most abundant of which was trinucleotide (16.2%) followed by mononucleotide (14.3%). All types of repeat motif (mono-, di-, tri-, tetra- and pentanucleotide) were detected except hexanucleotide motifs. According to SSRs analysis, the most abundant observed motifs were identified for mono-, di-, tri-, tetra- and pentanucleotide cpSSRs A/T, AT/TA, AAG/CTT, AAAG/AGTTT, and AATCC/ATTGG respectively. This study results provided scientific base for phylogenetics, evolutionary genetics and diversity studies on different Olea species in future.
Brachypodium Genomics
Bahar Sogutmaz Ozdemir,Pilar Hernandez,Ertugrul Filiz,Hikmet Budak
International Journal of Plant Genomics , 2008, DOI: 10.1155/2008/536104
Abstract: Brachypodium distachyon (L.) Beauv. is a temperate wild grass species; its morphological and genomic characteristics make it a model system when compared to many other grass species. It has a small genome, short growth cycle, self-fertility, many diploid accessions, and simple growth requirements. In addition, it is phylogenetically close to economically important crops, like wheat and barley, and several potential biofuel grasses. It exhibits agricultural traits similar to those of these target crops. For cereal genomes, it is a better model than Arabidopsis thaliana and Oryza sativa (rice), the former used as a model for all flowering plants and the latter hitherto used as model for genomes of all temperate grass species including major cereals like barley and wheat. Increasing interest in this species has resulted in the development of a series of genomics resources, including nuclear sequences and BAC/EST libraries, together with the collection and characterization of other genetic resources. It is expected that the use of this model will allow rapid advances in generation of genomics information for the improvement of all temperate crops, particularly the cereals.
Presence of factors that activate platelet aggregation in mitral stenotic patients' plasma
Istemihan Tengiz, Ertugrul Ercan, Fahri Sahin, Emin Alioglu, Can Duman, Guray Saydam, Filiz Buyukkececi
Trials , 2005, DOI: 10.1186/1468-6708-6-2
Abstract: Sixteen newly diagnosed patients with rheumatic MS (Group P) and 16 healthy subjects (Group N) were enrolled in the study. Platelet-equalized plasma samples were evaluated to determine in vitro platelet function, using adenosine diphosphate (ADP), collagen and epinephrine in an automated aggregometer. In vitro platelet function tests in group N were performed twice, with and without plasma obtained from group P.There were no significant differences between the groups with respect to demographic variables. Peripheral venous fibrinogen levels in Group P were not significantly different from those in Group N. Adenosine diphosphate, epinephrine and collagen-induced platelet aggregation ratios were significantly higher in Group P than in Group N. When plasma obtained from Group P was added to Group N subjects' platelets, ADP and collagen-induced, but not epinephrine-induced, aggregation ratios were significantly increased compared to baseline levels in Group N.Platelet aggregation is increased in patients with MS, while fibrinogen levels remain similar to controls. We conclude that mitral stenotic patients exhibit increased systemic coagulation activity and that plasma extracted from these patients may contain some transferable factors that activate platelet aggregation.Systemic thromboembolism represents a major complication in patients with mitral stenosis (MS), especially in those who have atrial fibrillation [1,2]. A hypercoagulable state has been reported in patients with MS and sinus rhythm [3,4]. The association between MS and higher levels of coagulation is well-known; however, the source of increased coagulation remains unclear. Increased regional left atrial coagulation activity may be involved, even when systemic coagulation assessed by peripheral blood sampling is normal [5,6]. Others have reported no significant variation in thrombogenesis, platelet activation, and endothelial dysfunction between the left atrium, right atrium and peripheral arteries or veins
Scientific data on selenium status in Turkey  [PDF]
Filiz Karadas
Agricultural Sciences (AS) , 2014, DOI: 10.4236/as.2014.52011

This review provides a summary of the available scientific data on selenium status in Turkey. The first reports regarding selenium status in Turkey appeared in the 1990s. Since then, much attention has been paid to selenium content in soil, cereal crops and a variety of other foodstuffs including corn, garlic, mushrooms, fresh and canned fish, meat and meat products, milk and dairy products, spice and condiment plants and honey. Previous reports by Foster and Summer (1997), Aras et al. (2001) and H?ncal (2007) reported daily selenium intake in Turkey to be 30 μg/day, 20-53 μg/day and 30-40 μg/day, respectively. However, these reports are based on limited local data and cannot be generalized for the entire country. As a result, there is still a need for further research in all seven regions and 81 provinces of the country to measure selenium content of soil, food, water and animal feed in order to determine the average daily selenium intake of animals and humans in Turkey.

Mannose Binding Lectin Deficiency and Clinical Features
Ertugrul Erken
Arsiv Kaynak Tarama Dergisi , 2013,
Abstract: Innate immunity consists of macrophages, neutrophils, natural killer cells, mucosal immunuglobulins and the comlement system. Mannose binding lectin (MBL) takes part in innate immunity through opsonisation and complement activation. MBL deficiency is associated with some infections and autoimmune disorders. However some studies indicate that MBL deficiency alone is not essential for immunity but it may intensify the clinic picture of an immune deficiency that already exists. This article refers to clincal studies related to MBL and brings up the clinical importance of MBL deficiency. [Archives Medical Review Journal 2013; 22(4.000): 565-574]
Multiple-Input Multiple-Output OFDM with Index Modulation
Ertugrul Basar
Mathematics , 2015, DOI: 10.1109/LSP.2015.2475361
Abstract: Orthogonal frequency division multiplexing with index modulation (OFDM-IM) is a novel multicarrier transmission technique which has been proposed as an alternative to classical OFDM. The main idea of OFDM-IM is the use of the indices of the active subcarriers in an OFDM system as an additional source of information. In this work, we propose multiple-input multiple-output OFDM-IM (MIMO-OFDM-IM) scheme by combining OFDM-IM and MIMO transmission techniques. The low complexity transceiver structure of the MIMO-OFDM-IM scheme is developed and it is shown via computer simulations that the proposed MIMO-OFDM-IM scheme achieves significantly better error performance than classical MIMO-OFDM for several different system configurations.
The Effect of Precooling of Lettuces and Green Beans on the Ratio of Weight Loss and Net Weight after Storage
Esref Isik,Ertugrul Celik
Pakistan Journal of Biological Sciences , 2006,
Abstract: In this study, we investigated the effects of precooling and not precooling lettuce types Lital and Yedikule to +2 and +4°C and fresh bean types Aysekadin and Rodop to +8°C in a vacuum cooler on the weight loss and net weight of the products at the end of storage. No statistical difference in poststorage weight loss was found between vacuum precooling treatments in the lettuce trials; however, there was a significant (p<0.01) effect of vacuum precooling on poststorage weight loss in beans. Packaging of precooled products affected weight loss of lettuces and beans (p<0.01) and (p<0.05) significance, respectively. The weight loss in packaged products at the end of the vacuum cooling process was 1.82 and 0.74% in lettuces and beans, respectively, whereas in unpackaged products it was 5.05 and 2.41%. Plant types and packages affected the net weight of lettuces significance (p<0.01). Lital was the best product type with 42.34% net weight and packaging products was the best method with 44.95% net weight. No change in net weight was observed in the beans because there was no spoilage after storage.
Comparison of Generalized Estimating Equations' Performance in Clustered Binary Observations
Ertugrul COLAK,Kazim OZDAMAR
Trakya Universitesi Tip Fakultesi Dergisi , 2007,
Abstract: Objectives: The objective of this study is to compare the performance of generalized estimating equations (GEE) for analysis of clustered binary observations under varying group and observation numbers according to intraclass correlation coefficients (ICC).Materials and Methods: The comparison of GEE performance was made by using bias of parameter estimations through computer simulations under varying group sizes, ICC, number of clusters, and number of observations per cluster. Simulations were performed in SAS 9.0 by using Monte Carlo simulation method. Analyses were made with SAS GENMOD procedure.Results: When intraclass correlation coefficient was low (ICC<0.10), there was no significant difference in parameter estimation and their biases and it was observed that GEE gave reliable, consistent and unbiased estimations. However, when ICC increased (ICC>0.10), it was found that the parameter estimations were significantly biased. On the condition that total sample size is fixed; it was observed that, even though the general sample size was constant in all groups while the number of groups was decreasing, when the number of observations per cluster increased, parameter estimations and their biases weren't affected significantly and the effective factor in parameter estimation was ICC.Conclusion: Because GEE method uses population averaged logistic regression approach, it cannot explain the changes and correlations in clusters completely. The use of GEE method is inconvenient particularly for data sets which have ICC greater than 0.10.
Choice of drugs in the treatment of chronic hepatitis B in pregnancy
Ertugrul Guclu,Oguz Karabay
World Journal of Gastroenterology , 2013, DOI: 10.3748/wjg.v19.i10.1671
Abstract: The selection of antiviral drugs for chronic hepatitis B (CHB) treatment in pregnancy is very difficult since none of the drugs have been approved for use in pregnancy. Transmission from mother to newborn remains the most frequent route of infection in mothers with high viral load and positive hepatitis B e antigen status, even with the use of appropriate prophylaxis with hepatitis B virus (HBV) immunoglobulin and HBV vaccination. We read from the article written by Yi et al that lamivudine treatment in early pregnancy was safe and effective. However, we could not understand why adefovir dipivoxil (ADV) was used in three pregnancy cases, since ADV has been classified as pregnancy category C. In pregnancy, telbivudine or tenofovir should be selected when the treatment of CHB is necessary, since these drugs have been classified as Food and Drug Administration pregnancy risk category B.
High-Rate Full-Diversity Space-Time Block Codes for Three and Four Transmit Antennas
Ertugrul Basar,Umit Aygolu
Mathematics , 2009,
Abstract: In this paper, we deal with the design of high-rate, full-diversity, low maximum likelihood (ML) decoding complexity space-time block codes (STBCs) with code rates of 2 and 1.5 complex symbols per channel use for multiple-input multiple output (MIMO) systems employing three and four transmit antennas. We fill the empty slots of the existing STBCs from CIODs in their transmission matrices by additional symbols and use the conditional ML decoding technique which significantly reduces the ML decoding complexity of non-orthogonal STBCs while ensuring full-diversity and high coding gain. First, two new schemes with code rates of 2 and 1.5 are proposed for MIMO systems with four transmit antennas. We show that our low-complexity rate-2 STBC outperforms the corresponding best STBC recently proposed by Biglieri et al. for QPSK, due to its superior coding gain while our rate-1.5 STBC outperforms the full-diversity quasi-orthogonal STBC (QOSTBC). Then, two STBCs with code rates of 2 and 1.5 are proposed for three transmit antennas which are shown to outperform the corresponding full-diversity QOSTBC for three transmit antennas. We prove by an information-theoretic analysis that the capacities of new rate-2 STBCs for three and four transmit antennas are much closer to the actual MIMO channel capacity than the capacities of classical OSTBCs and CIODs.
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