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Search Results: 1 - 10 of 6106 matches for " EMMANUELLE COELHO NORONHA "
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Genetic polymorphism of GSTM1 in women with breast cancer and interact with reproductive history and several clinical pathologies
JOSé JUVENAL LINHARES,ISMAEL DALE COTRIM GUERREIRO DA SILVA,NAIARA C NOGUEIRA DE SOUZA,EMMANUELLE COELHO NORONHA
Biological Research , 2005,
Abstract: Due to the conflicting results regarding the association between breast cancerand the GSTM1 null mutation, our aim was to research this associationin a Brazilian population and correlations withsmoking, reproductive history and several clinical pathologies. A case-control study was performed on 105 women with breast cancer and 278 controls. Extraction of DNA was accomplished according to the protocol of the GFX kit and polymorphism analysis by the PCR technique. The control and experimental groups were compared and statistical analysis assessed by X2 or Fisher's exact test. The deletion in the GSTM1 gene in the breast cancer group had a prevalence of 32 (30.4%) individuals with the presence of null mutation. In the control group, the null mutation was present in 104 (37.4%) women. Upon comparison of the two groups, no statistically significant difference of the GSTM1 gene was observed, with an odds ratio (OR) of 0.74, 95%, confidence interval (CI) 0.45 - 1.20, p = 0.277. The results conclusively show that singlegene GSTM1 polymorphisms do not confer a substantial risk of breastcancer to its carriers. Furthermore, in this study no correlation was found between GSTs andsmoking, reproductive history and several clinical pathologies with respect to cancer risk.
Polimorfismo do gene do receptor de progesterona (PROGINS) em mulheres com cancer de mama: estudo caso-controle
Linhares, José Juvenal;Silva, Ismael Dale Cotrim Guerreiro da;Souza, Naiara Correa Nogueira de;Noronha, Emmanuelle Coelho;Ferraro, Odair;Baracat, Fausto Farah;
Revista Brasileira de Ginecologia e Obstetrícia , 2005, DOI: 10.1590/S0100-72032005000800007
Abstract: purpose: to analyze the correlation between progins polymorphism and breast cancer. methods: a case-control study was carried out from april to october 2004. the genotypes of 50 women with breast cancer and 49 healthy women were analyzed. the 306-base pair alu insertion polymorphism in the g intron of progesterone receptor gene was detected by polymerase chain reaction and analyzed on 2% agarose gel stained with ethidium bromide. the control and experimental groups were compared regarding genotypes using the statistical epi-info 6.0 program and for frequencies the exact fisher test or c2 test were used. p value smaller p than 5% was considered to be significant. results: in relation to progins we found in the studied population a prevalence of 62 (62.6%) wild homozygous, 35 (35.3%) heterozygous individuals and two (2.1%) cases with the presence of the mutation. regarding progins polymorphism, significance was not evidenced when cases and controls were compared, as related to homozygosis (62 vs 65.3%), heterozygosis (36 vs 34,6%) or the mutation (2.0 vs 2.1%), with p=0.920 (or=1.01), 0.891 (or=1.06), and 0.988 (or=1.10), respectively. conclusions: the results show that single-gene progins polymorphism does not confer a substantial risk of breast cancer to its carriers.
Genetic polymorphism of GSTM1 in women with breast cancer and interact with reproductive history and several clinical pathologies
LINHARES,JOSé JUVENAL; GUERREIRO DA SILVA,ISMAEL DALE COTRIM; NOGUEIRA DE SOUZA,NAIARA C; COELHO NORONHA,EMMANUELLE; FERRARO,ODAIR; DE CARVALHO,CRISTINA VALLETA; CHADA BARACAT,EDMUND; FARAH BARACAT,FAUSTO;
Biological Research , 2005, DOI: 10.4067/S0716-97602005000200017
Abstract: due to the conflicting results regarding the association between breast cancer and the gstm1 null mutation, our aim was to research this association in a brazilian population and correlations with smoking, reproductive history and several clinical pathologies. a case-control study was performed on 105 women with breast cancer and 278 controls. extraction of dna was accomplished according to the protocol of the gfx? kit and polymorphism analysis by the pcr technique. the control and experimental groups were compared and statistical analysis assessed by x2 or fisher's exact test. the deletion in the gstm1 gene in the breast cancer group had a prevalence of 32 (30.4%) individuals with the presence of null mutation. in the control group, the null mutation was present in 104 (37.4%) women. upon comparison of the two groups, no statistically significant difference of the gstm1 gene was observed, with an odds ratio (or) of 0.74, 95%, confidence interval (ci) 0.45 - 1.20, p = 0.277. the results conclusively show that single gene gstm1 polymorphisms do not confer a substantial risk of breast cancer to its carriers. furthermore, in this study no correlation was found between gsts and smoking, reproductive history and several clinical pathologies with respect to cancer risk.
Movilización de recursos y redes sociales en los neopopulismos: Hipótesis de trabajo para el caso chileno
Barozet,Emmanuelle;
Revista de ciencia política (Santiago) , 2003, DOI: 10.4067/S0718-090X2003000100004
Abstract: en este documento, presentamos el marco analítico y las hipótesis de trabajo de una investigación en curso, acerca de la emergencia y el desarrollo del liderazgo político de joaquín lavín, candidato a la presidencia en 1999 y alcalde de santiago centro, y jorge soria, alcalde de iquique, dos casos de liderazgo populista en chile, uno nacional y otro local, poniendo un especial énfasis en el análisis de las redes sociales en las cuales se sustentan. alejándonos de los enfoques institucionalistas y enfocándonos en su base social, consideramos que las adhesiones o simpatías que suscitan este tipo de liderazgos descansan en la instrumentalización de vínculos sociales rutinarios, tanto verticales como horizontales y tanto formales como informales, estructurados mediante redes duraderas, en especial en los sectores populares
Quand la sociologie des sciences se saisit de la sociologie de l'art
Sebbah, Emmanuelle;
Sociedade e Estado , 2005, DOI: 10.1590/S0102-69922005000300003
Abstract: si, classiquement, la sociologie des sciences est envisagée comme l'étude des activités relevant des sciences de la nature, c'est dans le cadre d'une sociologie des sciences humaines et sociales que l'on souhaite insérer nos propres recherches, et étudier la constitution de la sociologie de l'art en france, comme sous-discipline distincte des autres champs d'investigations de la sociologie et distincte des autres disciplines traditionnellement en charge de son objet: l'esthétique et l'histoire de l'art. c'est sur le premier moment du processus de "disciplinarisation" de la sociologie de l'art que nous nous arrêterons, à savoir son insertion au sein du projet durkheimien.
à quelles conditions une charte est-elle efficace ? What are the conditions for an efficient charter?
Emmanuelle Danblon
Argumentation et Analyse du Discours , 2010,
Abstract: Dans cet article, on soutient que la déclaration des droits de l’homme constitue un genre rhétorique dont les conditions d’efficacité peuvent s’analyser à trois niveaux : les conventions, les fictions et les motivations. Sa visée est la création d’un monde commun. On montre à travers l’exemple de la déclaration pour le droit des animaux comment une charte échoue à réaliser cette visée. In this paper, it is argued that the Declaration of Human Right is a rhetorical genre that is efficient if three conditions are fullfilled: the expression of conventions, of fictions and of motivations. The aim of such a genre is to create a common world. It is shown with the Declaration for Animals’ Rights how such a charter can fail to achieve this purpose.
A história do ensino superior francês: por uma abordagem global = For a Global Approach to the History of French Higher Education
Picard, Emmanuelle
Educa??o , 2010,
Abstract: A história do Ensino Superior francês contemporaneo foi objeto, desde os anos 1970, de importantes trabalhos franceses e estrangeiros, mas está ainda longe de suscitar tanto interesse quanto outros segmentos do ensino. Este artigo apresenta um panorama crítico da pesquisa nesta área e prop e uma periodiza o dos contextos de produ o e das temáticas dominantes, ao mesmo tempo em que reflete acerca das causas deste pequeno interesse. A apresenta o dos estudos em curso permite sugerir as orienta es para os próximos anos e conduz ao desenvolvimento de uma abordagem global da quest o.
Construction nationale en Amérique latine et histoire des femmes, (1860-1930)
Emmanuelle Sinardet
Genre & Histoire , 2011,
Abstract: Historia de las mujeres contribue à une meilleure connaissance des processus de consolidation des modèles d’états nationaux en Amérique latine, en cernant les multiples contributions des femmes au grand projet de construction nationale conduit par les élites au pouvoir durant les dernières décennies du XIXe et les premières du XXe siècle. Les femmes sont appelées à devenir les relais effectifs, dans la sphère privée et familiale, des actions menées par l’état centralisé en vue de créer un homme nouveau, capable de servir la visée modernisatrice du projet national. Historia de las Mujeres permet d’appréhender le r le de l’état dans la définition de nouvelles représentations et dans l’émergence d’un sujet féminin, ainsi que de comprendre l’affirmation, à partir des années trente et quarante, des féminismes latino-américains auparavant en gestation.
Entrega de la medalla conmemorativa
Emmanuelle Sinardet
Perfiles educativos , 2004,
Abstract:
Recovering the History of the French University
Emmanuelle Picard
Studium : Tijdschrift voor Wetenschaps- en Universiteits-Geschiedenis , 2013,
Abstract: The history of French universities is characterised by several ruptures since the French Revolu- tion, the last of them dating from 1968 and resulting in the breakup of existing universities into multiple entities without their own past. Simultaneously, a culture of intense centralization served as a guiding principle in the design of the French academic system, leading to the disappearance of all, indeed minor, attempts to create a culture of autonomous institutions. Against this background, it becomes clear why the bulk of the historiography on French universities has focused on the academic disciplines and rarely mentions universities as institutions. Scholars identified themselves first and foremost with their scientific field, with their institutional affiliation playing only a secondary role. By discussing these specific characteristics of the French university system, this article aims to elucidate the problems French universities are confronted with when eager to commemorate their own past.
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