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Search Results: 1 - 10 of 339283 matches for " E.N. Loginova "
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Results of the CAMELLIA trail: implementation in a primary health care
G.I. Nechaeva,E.N. Loginova
Rational Pharmacotherapy in Cardiology , 2009,
Abstract: Aim. To compare the antihypertensive and metabolic effects of combined therapy (carvedilol reception and School of the hypertensive patient ) with these of the carvedilol monotherapy in young patients with arterial hypertension (HT) of 1-2 degrees with overweight and obesity.Material and methods. 63 out-patients with HT of 1-2 degrees (aged 18-27 y.o.) with overweight and obesity were included in the open parallel randomized clinical preventive trail. Patients wеre randomized into 2 groups. All hypertensive patients received the carvedilol (Vedicardol, Sintez, Russia) 25 mg daily. Carvedilol dose was enlarged twice in case of insufficient antihypertensive effect. Patients of the main group (n=32) also passed through the special educational program School for hypertensive patients . Changes in blood pressure (BP) level, body mass index, biochemical markers and risk factors were evaluated initially and in 24 weeks of therapy.Results. Patients of the main group had more significant risk factor manifestations decrease than in group of comparison. More significant body mass index decrease was also observed in the main group in comparison with group of comparison: from 32,5±0,4 to 26,4±0,7 kg/m2 (p<0,01) and from 31,8±0,8 to 28,9±1,18 kg/m2 (p<0,05), respectively. In patients of the main group systolic and diastolic BP decreased by 20,1% and 25,6%, respectively, wile in patients of the group of comparison – by 18,9% and 26%, respectively.Conclusion. It is reasonable to combine carvedilol therapy with special training in the young hypertensive patients with overweight and obesity.
Clinical and cost effectiveness of preventive counseling of young patients with arterial hypertension in primary health care
M.I. Shupina,O.Ju. Korennova,E.N. Loginova
Rational Pharmacotherapy in Cardiology , 2013,
Abstract: Aim. To study clinical and cost effectiveness of training of young patients with arterial hypertension (HT) in the health school in comparison with individual counseling.Material and methods. Hypertensive outpatients (n=114) at the age of 18-27 years were included into the study. Patients were randomized into 2 groups: “Health school” and "Typical practice". “Health school” patients received special training course “School health for patients with HT." Patients of the "Typical practice" had individual consultation. Clinical and cost analysis was performed in 6, 12 and 36 months of the follow-up.Results. The total cardiovascular risk in patients of “Health school” and "Typical practice" groups after 12 months decreased from 15.85±3.47% to 7.22±2.59% and from 15.60±3.34% to 11.29±4.14%, respectively, after 36 months to 10.77±3.18% and to 11.40±3.93%, respectively. Cost of 1% reduction in the total cardiovascular risk was 3425.1 and 190.4 rubles per one patient in “Health school” and "Typical practice" groups, respectively.Conclusion. The more time after the training course passes, the more its clinical and cost effectiveness reduces. This requires a follow-up care and repeated preventive counseling of these patients.
Interactions between intracellular Ca2+ stores: Ca2+ released from the NAADP pool potentiates cADPR-induced Ca2+ release
Chini, E.N.;
Brazilian Journal of Medical and Biological Research , 2002, DOI: 10.1590/S0100-879X2002000500005
Abstract: cells possess multiple intracellular ca2+-releasing systems. sea urchin egg homogenates are a well-established model to study intracellular ca2+ release. in the present study the mechanism of interaction between three intracellular ca2+ pools, namely the nicotinic acid adenine dinucleotide phosphate (naadp), the cyclic adp-ribose (cadpr) and the inositol 1',4',5'-trisphosphate (ip3)-regulated ca2+ stores, is explored. the data indicate that the naadp ca2+ pool could be used to sensitize the cadpr system. in contrast, the ip3 pool was not affected by the ca2+ released by naadp. the mechanism of potentiation of the cadpr-induced ca2+ release, promoted by ca2+ released from the naadp pool, is mediated by the mechanism of ca2+-induced ca2+ release. these data raise the possibility that the naadp ca2+ store may have a role as a regulator of the cellular sensitivity to cadpr.
The choice of strategic alternatives to building the capacity of rail
E.N. Chupir
Marketing ì Mened?ment Innovacìj , 2012,
Abstract: The article is devoted to theoretical aspects of the choice of an enterprise development strategy. It is proposed matrix of strategic choice areas for development.
Integrated investment- innovation processes groups of companies: essence and sequence
E.N. Chupyr
Marketing ì Mened?ment Innovacìj , 2012,
Abstract: The authors elucidate the nature, content and implementation stages of an integrated investment -innovation process.
Human factors that derail extension services delivery in developing countries: implications for policy
E.N. Ajani
International Journal of Agricultural Research, Innovation and Technology : IJARIT , 2012,
Abstract: The paper examines human factors derailing extension services delivery in developing countries. Poor management of rewards and incentives; quality of work life; poor assessment system; limited quality of human resource; inadequate extension support training materials; inconsistencies of government programmes; inadequate staff training and poor extension programme evaluation were viewed as major constraints. Considering the role of extension to agricultural development, the paper recommends that efforts should be made by the various stakeholders in agricultural extension services to improve the capability of human resources involved in extension services and highlights the need for government agricultural programmes to be consistent to enable the beneficiaries of such programmes derive the benefits that will boost productivity in agriculture.
Assessment of use of indigenous maize storage practices among farmers in anambra state, Nigeria
E.N. Ajani
International Journal of Agricultural Research, Innovation and Technology : IJARIT , 2012,
Abstract: The study assessed the use of indigenous maize storage practices among farmers in Anambra State, Nigeria. Data for the study was collected by the use of interview schedule from a sample of 60 respondents. Percentage, mean score and standard deviation were used for analyzing data collected for the study. Results revealed that the farmers were using indigenous technologies such as baskets, aerial (over fire) in the kitchen, bare floors, among others in storing maize. The respondents indicated that they stored maize cobs undehusked in order to overcome wastage and obtained information about indigenous storage of maize from parents and fellow farmers. Major problems militating against effective storage of maize include: attack of pests such as rodents and weevils, diseases, termite attack and use of poor quality storage materials. The respondents indicated that use of materials free from termite, clearing of surroundings against fire disaster; use of durable materials treated with insecticides will help to solve the problems. The study recommends that provision of appropriate and affordable storage structures should be made available to the maize farmers in order to avoid wasting of the produce under storage. This will help to ensure food security among rural farm households.
Interactions between intracellular Ca2+ stores: Ca2+ released from the NAADP pool potentiates cADPR-induced Ca2+ release
Chini E.N.
Brazilian Journal of Medical and Biological Research , 2002,
Abstract: Cells possess multiple intracellular Ca2+-releasing systems. Sea urchin egg homogenates are a well-established model to study intracellular Ca2+ release. In the present study the mechanism of interaction between three intracellular Ca2+ pools, namely the nicotinic acid adenine dinucleotide phosphate (NAADP), the cyclic ADP-ribose (cADPR) and the inositol 1',4',5'-trisphosphate (IP3)-regulated Ca2+ stores, is explored. The data indicate that the NAADP Ca2+ pool could be used to sensitize the cADPR system. In contrast, the IP3 pool was not affected by the Ca2+ released by NAADP. The mechanism of potentiation of the cADPR-induced Ca2+ release, promoted by Ca2+ released from the NAADP pool, is mediated by the mechanism of Ca2+-induced Ca2+ release. These data raise the possibility that the NAADP Ca2+ store may have a role as a regulator of the cellular sensitivity to cADPR.
Ocean Acidification and Coral Reefs: An Emerging Big?Picture
John E.N. Veron
Diversity , 2011, DOI: 10.3390/d3020262
Abstract: This article summarises the sometimes controversial contributions made by the different sciences to predict the path of ocean acidification impacts on the diversity of coral reefs during the present century. Although the seawater carbonate system has been known for a long time, the understanding of acidification impacts on marine biota is in its infancy. Most publications about ocean acidification are less than a decade old and over half are about coral reefs. Contributions from physiological studies, particularly of coral calcification, have covered such a wide spectrum of variables that no cohesive picture of the mechanisms involved has yet emerged. To date, these studies show that coral calcification varies with carbonate ion availability which, in turn controls aragonite saturation. They also reveal synergies between acidification and the better understood role of elevated temperature. Ecological studies are unlikely to reveal much detail except for the observations of the effects of carbon dioxide springs in reefs. Although ocean acidification events are not well constrained in the geological record, recent studies show that they are clearly linked to extinction events including four of the five greatest crises in the history of coral reefs. However, as ocean acidification is now occurring faster than at any know time in the past, future predictions based on past events are in unchartered waters. Pooled evidence to date indicates that ocean acidification will be severely affecting reefs by mid century and will have reduced them to ecologically collapsed carbonate platforms by the century’s end. This review concludes that most impacts will be synergistic and that the primary outcome will be a progressive reduction of species diversity correlated with habitat loss and widespread extinctions in most metazoan phyla.
FOUNDATIONS OF THE NEW SOUTH AFRICA
E.N. De Agrela
Scientia Militaria : South African Journal of Military Studies , 2012, DOI: 10.5787/25-1-269
Abstract: As a history teacher to Forms 4 and 5 (Standard 9 and 10), John Pampallis found that "a pressing need for a general textbook to cover the South African section of our syllabus" existed. Pampallis set out to document the history of South Africa and the fruits of his labour emerged in the form of his book Foundations of the New South Africa which is written from refreshingly different perspective.
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