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Search Results: 1 - 10 of 167695 matches for " E.; Fusté "
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La opinión de los profesionales sanitarios sobre el Plan de Salud de Catalu a: punto de partida para una reflexión orientada al futuro
Brugulat P.,Séculi E.,Fusté J.,Juncà S.
Gaceta Sanitaria , 2003,
Abstract: Objetivos: Conocer la opinión de los profesionales sanitarios sobre el Plan de Salud (PS) de Catalu a y obtener nuevos elementos para la formulación y gestión de nuevos planes. Dise o: Combinación de metodología cuantitativa y cualitativa. Encuesta postal a personal médico y de enfermería, por muestreo aleatorio polietápico con estratificación. Se obtuvieron 3.223 cuestionarios (tasa de respuesta del 34,1%). Entrevista a una muestra de conveniencia formada por 41 profesionales asistenciales y de la gestión. Mediciones y resultados principales: El PS es conocido por el 78,8% (intervalo de confianza del 95%: ± 1,4) de los profesionales y es valorado positivamente por la mayoría de los consultados. Según el 28,9% (IC del 95%: ± 1,7) de los encuestados que lo conocen, el PS ha tenido repercusiones favorables en su labor diaria, y el 51,8% (IC del 95%: ± 1,9) opina que no ha tenido repercusiones. Se critican aspectos de su elaboración, contenido, difusión y la escasa asignación de recursos específicos. Se observan diferencias por edad, sexo, ámbito asistencial y colectivo profesional. Conclusiones: Es necesaria una mayor implicación de los profesionales en la discusión, dise o e implementación de las propuestas del PS. Se debe avanzar en la identificación de problemas, en el establecimiento de prioridades y en la asignación de recursos. También hay que lograr un mayor compromiso intersectorial y desarrollar estrategias de comunicación específicas para políticos, gestores y profesionales que permitan mejorar la proyección de los objetivos del PS en el sistema sanitario y otros sectores con responsabilidad en el ámbito de la salud. En definitiva, es necesario replantearse el papel del PS en el sistema y, de acuerdo con él, redise ar los procesos para el establecimiento y aplicación de estrategias de salud.
Els pares i la renovació pedagògica
Xavier Fusté
Temps d'Educació , 1995,
La opinión de los profesionales sanitarios sobre el Plan de Salud de Catalu?a: punto de partida para una reflexión orientada al futuro
Brugulat,P.; Séculi,E.; Fusté,J.; Juncà,S.; Martínez,V.; Medina,A.; Mercader,M.; Sánchez,E.;
Gaceta Sanitaria , 2003, DOI: 10.1590/S0213-91112003000100009
Abstract: objectives: to know health professional's opinion of the health plan for catalonia (spain) in order to get news elements for the formulation and management of new plans. design: combination of quantitative and qualitative methodologies. postal survey to doctors and nurses (multistage randomised sample). 3.223 questionnaires were obtained (response rate: 34,1%). interview to a selected sample of 41 health care professionals and managers. measurements and main results: 78,8% (ic95%: ± 1,4) of health professionals are familiar with the health plan, and for most of them it is valued as important. 28,9% (ic95%: ± 1,7) of the professionals who know the plan consider that it has repercussions in their daily work and 51,8% (ic95%: ± 1,9) declare that it doesn't have any repercussions. different issues such as the planning process, the contents, the dissemination strategy, as well as a the poor impact on the health budget are critised. differences by age group and sex, care setting and type of health professional are observed. conclusions: the implication of health professionals in the discussion, formulation and implementation of the health plan proposals needs to be improved. it will be necessary to make progress in identifying health problems and needs, in setting priorities and in the allocation of resources. to increase the multisectorial involvement and to develop marketing strategies directed to politicians, managers and health professionals will also be needed in order to increase the impact of the health plan on both the health system and the other sectors involved in health. the role to be played by the health plan in the health system must be redefined and this will lead to redesigning the planning process and the implementation of health strategies.
Quality of dietary control in phenylketonuric patients and its relationship with general intelligence
Vilaseca,M. A.; Lambruschini,N.; Gómez-López,L.; Gutiérrez,A.; Fusté,E.; Gassió,R.; Artuch,R.; Campistol,J.;
Nutrición Hospitalaria , 2010,
Abstract: objectives: assessment of the quality of dietary treatment of phenylketonuria (pku) patients and investigation of its relationship with the general intelligence of the patients. methods: cross-sectional and longitudinal study of 105 pku treated patients. the index of dietary control (idc) was calculated as the phenylalanine (phe) data reduction in half-year medians and the mean of all medians throughout the patient's life. we calculated four different idcs related to age: idc-a (< 6 years), idc-b (6-12 years), idc-c (13-18 years) and idc-d (> 18 years). to evaluate the fluctuation of phe values we calculated the standard error of the estimate of the regression of phe concentration over age. development quotient was calculated with the brunet-lezine test (< 4 years). intelligence quotient was evaluated with the kaufman bit intelligence test (k-bit), wechsler intelligence scale for children-revised (wisc-r) and wechsler adult intelligence scale third edition (wais iii). results: cross-sectional study: the idc in age groups were significantly different and so were the number of patients with good, acceptable and poor idc related to age (p < 0.001). sampling frequency was good in 72, acceptable in 23 and poor in 10 patients. the general intelligence (101 ± 10) correlated negatively with the idc (p < 0.0001) and phe fluctuations (p < 0.004). longitudinal study: significant differences were observed between the idc through the patients' lifetime except in the adolescent/adult period. conclusions: 85% of pku patients showed good/acceptable quality of dietary control. general intelligence correlates with the idc at all ages, which highlights the importance of good control to achieve good prognosis.
Molecular Phylogenetics and Temporal Diversification in the Genus Aeromonas Based on the Sequences of Five Housekeeping Genes
J. Gaspar Lorén, Maribel Farfán, M. Carmen Fusté
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0088805
Abstract: Several approaches have been developed to estimate both the relative and absolute rates of speciation and extinction within clades based on molecular phylogenetic reconstructions of evolutionary relationships, according to an underlying model of diversification. However, the macroevolutionary models established for eukaryotes have scarcely been used with prokaryotes. We have investigated the rate and pattern of cladogenesis in the genus Aeromonas (γ-Proteobacteria, Proteobacteria, Bacteria) using the sequences of five housekeeping genes and an uncorrelated relaxed-clock approach. To our knowledge, until now this analysis has never been applied to all the species described in a bacterial genus and thus opens up the possibility of establishing models of speciation from sequence data commonly used in phylogenetic studies of prokaryotes. Our results suggest that the genus Aeromonas began to diverge between 248 and 266 million years ago, exhibiting a constant divergence rate through the Phanerozoic, which could be described as a pure birth process.
Divergent evolution and purifying selection of the flaA gene sequences in Aeromonas
Maribel Farfán, David Mi?ana-Galbis, M Carmen Fusté, J Gaspar Lorén
Biology Direct , 2009, DOI: 10.1186/1745-6150-4-23
Abstract: We sequenced the complete flagellin gene (flaA) in 18 different species and subspecies of Aeromonas. Sequences ranged in size from 870 (A. allosaccharophila) to 921 nucleotides (A. popoffii). The multiple alignment displayed 924 sites, 66 of which presented alignment gaps. The phylogenetic tree revealed the existence of two groups of species exhibiting different FlaA flagellins (FlaA1 and FlaA2). Maximum likelihood models of codon substitution were used to analyze flaA sequences. Likelihood ratio tests suggested a low variation in selective pressure among lineages, with an ω ratio of less than 1 indicating the presence of purifying selection in almost all cases. Only one site under potential diversifying selection was identified (isoleucine in position 179). However, 17 amino acid positions were inferred as sites that are likely to be under positive selection using the branch-site model. Ancestral reconstruction revealed that these 17 amino acids were among the amino acid changes detected in the ancestral sequence.The models applied to our set of sequences allowed us to determine the possible evolutionary pathway followed by the flaA gene in Aeromonas, suggesting that this gene have probably been evolving independently in the two groups of Aeromonas species since the divergence of a distant common ancestor after one or several episodes of positive selection.This article was reviewed by Alexey Kondrashov, John Logsdon and Olivier Tenaillon (nominated by Laurence D Hurst).The genus Aeromonas belonging to the Gammaproteobacteria includes a group of 21 Gram- negative bacterial species that can be isolated worldwide from a variety of environments. Although it is clear that members of this genus are primarily aquatic organisms, they can colonize other habitats and cause infections in invertebrates and vertebrates [1]. Recently, in their report of March 2006, the Office of Water of the Environmental Protection Agency of the USA (EPA) included some species of Aeromonas into
Real-time PCR quantification of human complement C4A and C4B genes
Agnes Szilagyi, Bernadett Blasko, Denes Szilassy, George Fust, Maria Sasvari-Szekely, Zsolt Ronai
BMC Genetics , 2006, DOI: 10.1186/1471-2156-7-1
Abstract: A novel quantitative real-time PCR (qPCR) technique was developed for rapid and accurate quantification of the C4A and C4B genes applying a duplex, TaqMan based methodology. The reliable, single-step analysis provides the determination of the copy number of the C4A and C4B genes applying a wide range of DNA template concentration (0.3–300 ng genomic DNA). The developed qPCR was applied to determine C4A and C4B gene dosages in a healthy Hungarian population (N = 118). The obtained data were compared to the results of an earlier study of the same population. Moreover a set of 33 samples were analyzed by two independent methods. No significant difference was observed between the gene dosages determined by the employed techniques demonstrating the reliability of the novel qPCR methodology. A Microsoft Excel worksheet and a DOS executable are also provided for simple and automated evaluation of the measured data.This report describes a novel real-time PCR method for single-step quantification of C4A and C4B genes. The developed technique could facilitate studies investigating disease association of different C4 isotypes.The complement system is a major constituent of innate immunity. Complement C4 plays an essential role in the activation cascades of the classical complement pathway as a subunit of the C3 and C5 convertases. C4 genes, located on the short arm of chromosome 6, are present either in a long (21 kilobasepair, kb) or in a short (14.6 kb) form, the long variant contains a 6.36 kb endogenous retrovirus HERV-K in its intron 9 [1,2]. These genes are deleted or duplicated together with the adjacent genes including RP (serine-threonine kinase), CYP21 (steroid 21-hydroxylase) and TNX (tenascin-X). The set of the four genes (RP, C4A or C4B, CYP21 and TNX) is referred to as the RCCX module [3]. The variation of the number of RCCX modules and sizes of the C4 genes leads to different RCCX length forms (Fig (1)): besides the monomodular L (long) and S (short), the bimodu
Población con cobertura pública o doble cobertura de aseguramiento sanitario: ?Cuál es la diferencia?
Fusté,Josep; Séculi,Elisa; Brugulat,Pilar; Medina,Antonia; Juncà,Salvi;
Gaceta Sanitaria , 2005, DOI: 10.1590/S0213-91112005000100005
Abstract: objective: to identify differences in socioeconomic characteristics, health status, health services' utilization, and satisfaction with health services between the population with public healthcare coverage only and the population with double healthcare coverage through additional affiliation to mutual or private health insurance companies. methods: data from the 2002 catalan health interview survey with interviews to 8,400 individuals were used. individuals with public healthcare insurance were differentiated from those who also had private health insurance. multivariate logistic regression analysis was used. results: a total of 99.2% of the population reported public healthcare coverage and 24.7% also had voluntary mutual or private insurance. individuals with double coverage were younger, had a high level of education, belonged to advantaged classes, and reported better self-perceived health and fewer chronic diseases and disabilities. no significant differences in the percentage of individuals who reported visiting a health professional in the previous 15 days were observed. significant differences in the type of professional visited were observed: 65% of individuals with public healthcare coverage only visited primary care settings but 51.1% of those with double coverage visited specialists. the proportion of persons reporting that they were satisfied or very satisfied with professional attitudes, waiting times and administrative procedures was higher in the double coverage group. conclusions: distinct sociodemographic and health profiles were found between persons with public coverage only and those with double coverage. health services' utilization also differed between the two groups.
Un caso de galactorrea psicógena sin hiperprolactinemia o síndrome de Nunes
Toll Clavero,J.; Fusté i Vallverdú,R.; Gutiérrez Noguera,R.; Redondo Guitarte,N.;
Medifam , 2001, DOI: 10.4321/S1131-57682001001000007
Abstract: various studies have proven the existence of psychological factors which play an important role in many cases of women that suffer hyperprolactinemia, galactorrhea or even prolactinoma (phenomenon known as the nunes syndrome). childhood experiences have been described that generate somatic disorders: divorce or absence of the father, or an alcoholic or/and violent father inducing to infantile regression where the mother and daughter get back to a symbiotic hateful relation symbolized in the lactance period. we present the case of a patient who manifests an euprolactinemia galactorrhea that coincides with the birth and lactance activities of a girlfriend of her.
Irradiación de tabletas de polen: Estudio de dosis
Rodríguez Jorge,Mayra; Guerra Ordó?ez,Marta; Padrón Soler,Eloy; Fusté Moreno,Viviana;
Revista Cubana de Farmacia , 1995,
Abstract: el polen constituye una fuente rica de nutrientes para el hombre; sin embargo, dado su origen los productos elaborados a partir de él suelen resultar de una inadecuada calidad higiénica, lo que los sitúa fuera de las especificaciones establecidas en el país, por lo que es necesario en estos casos la aplicación de un método de descontaminación adecuado. el presente trabjo tuvo por objetivo estudiar las posibilidades de radiodescontaminación de tabletas de polen 125 mg mediante la aplicación de diferentes niveles de dosis de radiaciones gamma (2-10 kgy). se realizaron evaluaciones microbiológicas y fisicoquímicas pre y postratamiento y se encontró que 6 kgy como dosis mínima es la dosis adecuada de irradiación para lograr el objetivo propuesto.
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