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Search Results: 1 - 10 of 167938 matches for " E. Kemp "
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Physical activity levels and energy expenditure of 9-year-old – 12-year-old overweight and obese children
Chanelle Kemp,Anita E. Pienaar
Health SA Gesondheid , 2011, DOI: 10.4102/hsag.v16i1.557
Abstract: The high occurrence of overweight and obesity amongst children is a disturbing health problem worldwide. Possible causes of increasing childhood obesity are inactivity and energy imbalances. The aim of this study was to analyse the total energy expenditure (TEE)and physical activity levels in 9-year-old – 12-year-old overweight and obese children during a weekday and a weekend day, as well as during a weekday morning and afternoon. Twenty-four 9-year-old – 12-year-old children (seven boys and 17 girls), of whom nine were overweight and 15 were obese, were selected from seven public primary schools for this study. Body mass index (BMI) cut-off points were used to distinguish between overweight and obese. Each participant wore an ACTICAL monitor to determine their physical activity levels and TEE. It was found that the TEE of the children did not differ between a week day and a weekend day, although the TEE of the week day afternoon differed significantly from that of the weekday morning. Unlike the overweight children, none of the obese children met the requirements of 60 minutes of moderate-intensity physical activity per day. Strategies should be found to increase the activity levels of overweight and, especially, obese children, specifically during the mornings and over weekends. Opsomming Die ho voorkoms van oorgewig en obesiteit onder kinders is wêreldwyd ’n kommerwekkende gesondheidsprobleem. Fisieke onaktiwiteit en energiewanbalanse word as moontlike oorsake van die probleem beskou. Die doel van hierdie studie was om die totale energieverbruik (TEV) en fisieke-aktiwiteitsvlakke van 9-jarige – 12-jarige oorgewig- en obese kinders tydens ‘n totale weeksdag en naweekdag te ontleed, asook tydens die oggend en middag van ‘n weeksdag. Vier-en-twintig 9-jarige – 12-jarige kinders (sewe seuns en 17 dogters), waarvan nege oorgewig en 15 obees was, is uit sewe publieke laerskole vir die studie gekies. Afsnypunte volgens die liggaamsmassa-indeks (LMI) is gebruik om tussen oorgewig en obees te onderskei. Elke deelnemer het ‘n ACTICAL monitor gedra om hul fisieke-aktiwiteitsvlakke en TEV te bepaal. Die studie het getoon dat die TEV van die kinders op ’n weeksdag en naweekdag nie verskil het nie, alhoewel TEV tydens die middag van die weeksdag betekenisvol verskil het van die oggend s’n. Anders as die oorgewig kinders, het geen van die obese kinders aan die voorgestelde riglyn van 60 minute se matig intensiewe fisieke aktiwiteit per dag voldoen nie. Strategie moet gevind word om die vlakke van aktiwiteit van oorgewig en veral obese kinders te verhoog, spesi
Duality in Segal-Bargmann Spaces
William E. Gryc,Todd Kemp
Mathematics , 2012, DOI: 10.1016/j.jfa.2011.05.014
Abstract: For $\alpha>0$, the Bargmann projection $P_\alpha$ is the orthogonal projection from $L^2(\gamma_\alpha)$ onto the holomorphic subspace $L^2_{hol}(\gamma_\alpha)$, where $\gamma_\alpha$ is the standard Gaussian probability measure on $\C^n$ with variance $(2\alpha)^{-n}$. The space $L^2_{hol}(\gamma_\alpha)$ is classically known as the Segal-Bargmann space. We show that $P_\alpha$ extends to a bounded operator on $L^p(\gamma_{\alpha p/2})$, and calculate the exact norm of this scaled $L^p$ Bargmann projection. We use this to show that the dual space of the $L^p$-Segal-Bargmann space $L^p_{hol}(\gamma_{\alpha p/2})$ is an $L^{p'}$ Segal-Bargmann space, but with the Gaussian measure scaled differently: $(L^p_{hol}(\gamma_{\alpha p/2}))^* \cong L^{p'}_{hol}(\gamma_{\alpha p'/2})$ (this was shown originally by Janson, Peetre, and Rochberg). We show that the Bargmann projection controls this dual isomorphism, and gives a dimension-independent estimate on one of the two constants of equivalence of the norms.
On Sharp Constants for Dual Segal--Bargmann $L^p$ Spaces
William E. Gryc,Todd Kemp
Mathematics , 2014,
Abstract: We study dilated holomorphic $L^p$ space of Gaussian measures over $\mathbb{C}^n$, denoted $\mathcal{H}_{p,\alpha}^n$ with variance scaling parameter $\alpha>0$. The duality relations $(\mathcal{H}_{p,\alpha}^n)^\ast \cong \mathcal{H}_{p',\alpha}$ hold with $\frac{1}{p}+\frac{1}{p'}=1$, but not isometrically. We identify the sharp lower constant comparing the norms on $\mathcal{H}_{p',\alpha}$ and $(\mathcal{H}_{p,\alpha}^n)^\ast$, and provide upper and lower bounds on the sharp upper constant. We prove several suggestive partial results on the sharpness of the upper constant. One of these partial results leads to a sharp bound on each Taylor coefficient of a function in the Fock space for $n=1$.
Using spherical wavelets to search for magnetically-induced alignment in the arrival directions of ultra-high energy cosmic rays
M. Zimbres,R. Alves Batista,E. Kemp
Physics , 2013, DOI: 10.1016/j.astropartphys.2013.11.001
Abstract: Due to the action of the intervening cosmic magnetic fields, ultra-high energy cosmic rays (UHECRs) can be deflected in such a way as to create clustered energy-ordered filamentary structures in the arrival direction of these particles, the so-called multiplets. In this work we propose a new method based on the spherical wavelet transform to identify multiplets in sky maps containing arrival directions of UHECRs. The method is illustrated in simulations with a multiplet embedded in isotropic backgrounds with different numbers of events. The efficiency of the algorithm is assessed through the calculation of Type I and II errors.
The prevalence of hypertension and the relationship with body composition in Grade 1 learners in the North West Province of South Africa
Chanelle Kemp, Anita E Pienaar, Aletta E Schutte
South African Journal of Sports Medicine , 2011,
Abstract: Objective. To determine the prevalence of hypertension in Grade 1 learners in the North West Province of South Africa and to investigate the association between blood pressure (BP) and body composition of these children. Methods. Data were collected by means of a stratified random sampling procedure from 816 Grade 1 learners (419 boys, 397 girls) with a mean age of 6.78±0.49 years (mean±SD), in the NWCHILD-study. Height, weight, skinfolds (subscapular, triceps, calf) and waist circumference were measured. The international recommended cut-off values of Cole et al. (2000) for body mass index (BMI) were used. Hypertension, defined as the average of two separate BP (BP) readings, where the systolic BP and diastolic BP is >95th percentile for age, sex and height, was determined by means of an Omron 705CP-II. Results. The overall prevalence of prehypertension and hypertension was 8.5% and 24.9%, respectively. Both systolic and diastolic BP was positively associated with BMI, body fat percentage and waist circumference. Boys and girls showed a similar prevalence of hypertension. A higher percentage of black children were hypertensive compared with whites, although the difference in BP of the groups was not significant. A high percentage of children with normal weight also showed increased levels of BP. Conclusions. High prevalences of hypertension were found in Grade 1 learners in the North West Province of South Africa. Small practical significant associations existed between BP and body composition. BP screening is therefore considered important in the paediatric population. Interventions which include physical activity are recommended to reduce potential cardiovascular complications and obesity among children. Other contributing factors to high BP amongst young children should also be investigated. SAJSM, vol 23 No. 4 2011
Malawi\'s Health SWAp: Bringing essential services closer to the poor?
D Gwatkin, E Kataika, I Cardinal, J Kemp
Malawi Medical Journal , 2006,
Abstract: The Government of Malawi has committed itself to reaching the poor with effective health services. The Government agreed to implement ‘The Essential Health Package\', re-affirmed its\' commitment to provide essential health services free of charge and undertook to monitor the new health Sector Wide Approach on its performance in reaching the poor. In August 2005, five papers were commissioned by the Equity and Access Sub-group of the Ministry of Health Monitoring and Evaluation Technical Working Group. The overarching recommendation arising from these analyses is the need to bring essential services much closer to the poor– not only in geographical proximity, but also affordability, cultural acceptability, and epidemiological relevance. The call is not to change policy, but rather to ensure its more energetic and effective implementation. Malawi Medical Journal Vol. 18 (1) 2006: pp. 1-4
Update on quetiapine in the treatment of bipolar disorder: results from the BOLDER studies
Prashant Gajwani,David J Muzina,David E Kemp,Keming Gao
Neuropsychiatric Disease and Treatment , 2007,
Abstract: Prashant Gajwani1, David J Muzina2, David E Kemp3, Keming Gao1, Joseph R Calabrese11Case Western Reserve University (CWRU) School of Medicine, 2Cleveland Clinic Lerner College of Medicine of CWRU, 3Case Western Reserve University, Cleveland OH, USAAbstract: The essential features of bipolar affective disorder involve the cyclical occurrence of high (manic or hypomanic episodes) and low mood states. Depressive episodes in both bipolar I and II disorder are more numerous and last for longer duration than either manic or hypomanic episodes. In addition depressive episodes are associated with higher morbidity and mortality. While multiple agents, including all 5 atypical antipsychotics, have demonstrated efficacy and earned US FDA indication for manic phase of bipolar illness, the acute treatment of bipolar depression is less well-studied. The first treatment approved by the US FDA for acute bipolar depression was the combination of the atypical antipsychotic olanzapine and the antidepressant fluoxetine. Recently, quetiapine monotherapy has demonstrated efficacy in the treatment of depressive episodes associated with both bipolar I and II disorder and has earned US FDA indication for the same.Keywords: bipolar disorder, quetiapine, BOLDER studies
Simon E. Engelhart,Benjamin P. Horton,Andrew C. Kemp
Oceanography , 2011,
Abstract: Reconstructions of Holocene relative sea level (RSL) have valuable applications in a number of topics within the Earth sciences, including calibrating and constraining geophysical models of Earth’s rheology and glacial isostatic adjustment. The usefulness of these reconstructions depends on application of a standardized methodology that fully considers all age and vertical errors. We outline this methodology and provide a detailed example from New Jersey. We describe Holocene RSL reconstructions from the US Atlantic coast that illustrate both spatial and temporal variability. Spatially, rates of Holocene RSL rise were greatest in the Mid Atlantic (New Jersey and Delaware) with decreasing rates of rise to the north and south. Temporally, rates of RSL rise have decreased since the early Holocene due to the combined effects of continued relaxation of the solid Earth in response to deglaciation and reduction in ice melt since 7000 years ago. A comparison of late Holocene (last 4000 years) geological reconstructions to long-term tide-gauge measurements reveal that sea level rise increased above background rates by an average of 1.7 mm yr-1 during the twentieth century.
Single cell transcriptional analysis reveals novel innate immune cell types
Linda E. Kippner,Jinhee Kim,Greg Gibson,Melissa L. Kemp
PeerJ , 2015, DOI: 10.7717/peerj.452
Abstract: Single-cell analysis has the potential to provide us with a host of new knowledge about biological systems, but it comes with the challenge of correctly interpreting the biological information. While emerging techniques have made it possible to measure inter-cellular variability at the transcriptome level, no consensus yet exists on the most appropriate method of data analysis of such single cell data. Methods for analysis of transcriptional data at the population level are well established but are not well suited to single cell analysis due to their dependence on population averages. In order to address this question, we have systematically tested combinations of methods for primary data analysis on single cell transcription data generated from two types of primary immune cells, neutrophils and T lymphocytes. Cells were obtained from healthy individuals, and single cell transcript expression data was obtained by a combination of single cell sorting and nanoscale quantitative real time PCR (qRT-PCR) for markers of cell type, intracellular signaling, and immune functionality. Gene expression analysis was focused on hierarchical clustering to determine the existence of cellular subgroups within the populations. Nine combinations of criteria for data exclusion and normalization were tested and evaluated. Bimodality in gene expression indicated the presence of cellular subgroups which were also revealed by data clustering. We observed evidence for two clearly defined cellular subtypes in the neutrophil populations and at least two in the T lymphocyte populations. When normalizing the data by different methods, we observed varying outcomes with corresponding interpretations of the biological characteristics of the cell populations. Normalization of the data by linear standardization taking into account technical effects such as plate effects, resulted in interpretations that most closely matched biological expectations. Single cell transcription profiling provides evidence of cellular subclasses in neutrophils and leukocytes that may be independent of traditional classifications based on cell surface markers. The choice of primary data analysis method had a substantial effect on the interpretation of the data. Adjustment for technical effects is critical to prevent misinterpretation of single cell transcript data.
Is there a universality of the helix-coil transition in protein models?
Josh P. Kemp,Ulrich H. E. Hansmann,Zheng Y. Chen
Physics , 2000, DOI: 10.1007/s100510051138
Abstract: The similarity in the thermodynamic properties of two completely different theoretical models for the helix-coil transition is examined critically. The first model is an all-atomic representation for a poly-alanine chain, while the second model is a minimal helix-forming model that contains no system specifics. Key characteristics of the helix-coil transition, in particular, the effective critical exponents of these two models agree with each other, within a finite-size scaling analysis.
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