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Search Results: 1 - 10 of 167657 matches for " E Zaharia-Kezdi "
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Characteristics of tuberculous meningitis in HIV-infected patients
A Hristea,C Manciuc,E Zaharia-Kezdi,C Dorobat
Journal of the International AIDS Society , 2012, DOI: 10.7448/ias.15.6.18413
Abstract: Background: Tuberculous meningitis (TBM) has a substantial mortality even with anti-tuberculous treatment, in HIV-non-infected patients. Purpose of the study. The objectives were to describe clinical and laboratory differences of TBM in HIV-infected versus HIV non-infected patients and to assess risk factors of death in HIV-infected patients. Methods: We retrospectively analyzed patients admitted to four infectious diseases hospitals in Romania, between 2001 and 2011, with TBM. Patients were defined as having TBM according to a consensus definition published by Marais et al. [1] and further divided into three categories of TBM (definite, probable and possible). Results: We identified 162 patients with TBM of which 47 (29%) tested positive for HIV infection. Sixty-six patients had definite, 53 probable and 43 possible TBM. Out of the 47 HIV-infected patients 25 had definite, 17 probable and 5 possible TBM. TBM in HIV-infected patients vs. HIV non-infected patients was significantly associated in multivariable analysis with younger age (p=0.01), in-hospital mortality (p<0.001), absence of meningean syndrome (p=0.021), and absence of cranial nerve palsy (p=0.036). HIV-infected patients who died had a median CD4 count of 61 cells/mm3 (IQR 21-132) vs. 135 cells/mm3 (IQR 61–255) in patients who survived (p=0.014). HIV infection was diagnosed before TBM episode in 35 (75%) patients. Twenty-four (51%) HIV-infected patients had concomitant extra-central nervous system tuberculosis. Conclusions: HIV infection is associated with increased mortality in patients with TBM. Most of our patients with TBM were late presenters. Death in HIV infected patients was associated with a lower median CD4 count.
Mesenchymal-to-Endothelial Transition in Kaposi Sarcoma: A Histogenetic Hypothesis Based on a Case Series and Literature Review
Simona Gurzu, Diana Ciortea, Teodora Munteanu, Iringo Kezdi-Zaharia, Ioan Jung
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0071530
Abstract: Objectives Although several studies have been conducted regarding Kaposi sarcoma (KS), its histogenesis still remains to be elucidated. The aim of our study was to analyze the immunophenotype of Kaposi sarcoma and to present a hypothesis about the histogenesis of this tumor, based on a case series and a review of relevant literature. Methods In 15 cases of KSs diagnosed during 2000–2011, the clinicopathological features were correlated with the immunoexpression of c-Kit, SMA, CD34, CD31, vascular endothelial growth factor (VEGF), COX-2, c-KIT, smooth muscle antigen (SMA), and stem cell surface marker CD105. Results Both CD105 and c-KIT rate of the spindle-shaped tumor cell positivity increased in parallel to the pathological stage. All cases displayed CD105 and weak c-KIT positivity in the endothelial cells. SMA, VEGF, and COX-2 were focally expressed in all cases. CD34 marked both endothelium and spindle-shaped tumor cells. No c-KIT expression was noticed in KS of the internal organs. Conclusions KS seems to be a variant of myofibroblastic tumors that originates from the viral modified pluripotent mesenchymal cells of the connective tissue transformed in spindle-shaped KS cells, followed by a mesenchymal-endothelial transition and a myofibroblastic-like differentiation. This paper mailnly showed that KS cannot be considered a pure vascular tumor.
The European Procedure on Reduced Value Claims
Alexandrina Zaharia,Adrian Zaharia
EIRP Proceedings , 2009,
Abstract: Maintaining and developing the area of freedom, security and justice is a major objective of theEuropean Community, which guarantees the free movement of persons. As a result of litigations regardingthe applications with a reduced value arising among physical or legal persons, it was felt the need for acommunity legislation that would guarantee identical conditions, both for creditors and debtors throughoutthe entire European Union territory. The European procedure regarding the debts recovery of reducedvalue facilitates the access to justice and it is characterized by simplifying and expediting the settling of thetransboundary litigations, reducing costs, the recognition and execution of the court order in a MemberState given in another Member State. This procedure is available to litigants as an alternative to theprocedures provided by the laws of Member States. The Regulation (EC) no. 861/2007 establishing aEuropean procedure regarding the applications with reduced value applies in civil and commercial matters inthe transboundary cases, regardless the nature of the court when the application value, without taking intoaccount the interest, expenditures and other costs, does not exceed 2000 Euro at the time of receiving theapplication form by the competent court. This procedure does not apply to revenue, customs oradministrative matters or in regard to state responsibility for acts or omissions in exercising the publicauthority, and other matters specifically referred to in the Regulation. A cause is transboundary in naturewhen one of the parties has its habitual residence in a Member State, other than the one where the courtreceives such application. The proper procedure of application resolution for the recovery of debts withreduced value is governed by the rules of procedural law of the Member State in which the proceedings areconducted, and the execution of court of law is made by state legislation in which it takes place. TheRegulation expressly provides that the court order in this matter can not be, in any form, the subject ofreexamination, in the State member in which its execution is requested. As regards the linguistic regime,the application will be written in the language or in one of the procedure languages of the court; the costsare incurred by the losing party in the application. But the court will not grant the party that won thelawsuit the expenses that were not necessary or the ones that have a disproportionate value in relation tothe application.
Riscuri ?i Catastrofe , 2012,
Abstract: The atmospheric precipitation, an essential meteorological element for defining the climatic potential of a region, presents through its general and local particularities a defining influence for the evolution of the other climatic parameters, conditioning the structure of the overall geographic landscape. Their quantitative parameters sets up the regional natural setting and differentiation of water resources, soil, vegetation and fauna, in the same time influencing the majority of human activities’ aspects, through the generated impact over the agriculture, transportation, construction, for tourism etc. Especially, through the evolution of the related climatic parameters (production type, quantity, duration, frequency, intensity) and their spatial and temporal fluctuations, the pluviometric extremes set out the maxim manifestation of the energy gap of the hydroclimatic hazards/risks which induce unfavourable or even damaging conditions for the human activities’ progress. Hence, the production of atmospheric precipitation surpluses conditions the triggering, or reactivation of some intense erosion processes, landslides, and last but not least, floods. Just as dangerous are the adverse amounts of precipitation or their absence on longer periods, determining the appearance of droughts, aridity phenomena, which if associated with the sharp anthropic pressure over the environment, favours the expansion of desertification, with the whole process of the arising negative effects. In this context, this paper aims to perform the diagnosis of atmospheric precipitation condition in Baia Mare urban area, through its quantitative component, in multiannual condition (1971-2007), underlining through the results of the analyzed climatic data and their interpretation, the main characteristics that define it. The data bank from Baia Mare station from the National Meteorological Administration network, representative for the chosen study area, was used. Baia Mare urban area overlaps Baia Mare depression, situated in the north-west side of the country, belonging, from a geographic perspective, to the West Hills, being limited by the Igni i Massif, Gutai la Mountains at north north-east, by the Chioarului and Codrului Hills at west and south, being drained by L pu , S sar, Bars u, Firiza, Jidovaia Rivers and others. The occupied geographic area by Baia Mare Depression benefits of a warm summer continental climate with predominant oceanic influences, being for most part of the year under the influence of oceanic air masses rich in humidity, due to west and north-west advec
Riscuri ?i Catastrofe , 2012,
Abstract: The landslides incidence in the piedmont of baia mare urbana area cae studies). The General Urban Plan (GUP) of Baia Mare municipality requires the study of expected susceptibility for landslides in order to build infrastructure within sustainable development conditions. The complexity and diversity of local geographic area factors, strongly affected by the human pressure, favours the triggering and extension of slope processes in the municipality’s piedmont area. To prevent some major imbalances it is imperative to implement some adequate measures based on in-depth studies.
PROFESSOR DR. ION PI OTA (1925 – 2008)
Lakes reservoirs and ponds , 2009,
Abstract: Professor Ion Pi ota was born on June 6, 1925, in Hrupi tea, a small settlement in Greek Macedonia, from where he and his family came to Romania in 1927, where he got Romanian citizenship. Between 1941 and 1945, he attended the Tulcea Boys High School and later on, in 1947 he entered the Faculty of Geology – Geography at the University of Bucharest, where he continued to excel until 1951, when he graduated. In the fall of 1950, he took up a tutor position in the field of Hydrolgy at the same faculty passing subsequently through all the stages of academic hierarchy until he became, in 1971, a University Professor. Even after he retired, in 1996, he continued his academic activity as a consultant professor within the same department and faculty that he served with passion and devotion for more than 50 years.
Lakes reservoirs and ponds , 2010,
Abstract: The paper makes a synthesis of the hydrological characteristics of the Iron Gates I reservoir and at the same time, it gives an account of its water quality state. A number of specific issues are revealed such as the feeding sources, level regime, water discharge, sediment load, and sedimentation processes. Likewise, the study highlights the alteration of the main hydrological parameters (levels, liquid and solid discharges) entailed by reservoir creation, by simply comparing the present day situation with that existing before the artificial lake came into being. The analysis of hydrological characteristics relies especially on the datasets provided by the “Romanian Waters” National Administration for the Bazia , Or ova and Drobeta Turnu Severin gauging stations, which have different recording intervals for the period 1921 – 2006. At the same time, bibliographic sources have been taken into account in order to better understand the hydrological phenomena. As far as water quality is concerned, this has been established based on the quality indicators for the periods 2000 – 2004 and 2006 – 2009, which exist in the records of the National Water Monitoring System.
Alexandrina ZAHARIA
Acta Universitatis Danubius : Juridica , 2005,
Abstract: The report of private international law differs from the national report by the existence of one or more elements of foreign origin. The latter determines in some cases the application of the internal or unified material norms and in other cases gives rise to conflict of laws, being the main factor in the legal partition reports of private international law by other legal reports. The legal elements of foreign origin can cause the following procedural issues a) the jurisdiction competence in private international law, this matter is regulated in particular by the speculation of article no. 148-157, Law 105/1992; b) the applicable procedure in the processes of international private law in the Romanian private international law; c) the consequences of judicial final judgments and foreign arbitration in Romanian private international law
Alexandrina ZAHARIA
Acta Universitatis Danubius : Juridica , 2007,
Abstract: In Romania, justice is achieved through the courts established by law. The patrimonial litigations appeared between the judicial persons may settle on the path of arbitration only if the parties expressly foresee this manner at the arbitrary convention. For such agreement to be valid the persons should have full capacity to exercise and the litigations should not be within the stage of which law does not allow the conclusion of a transaction. The arbitrary Convention with its forms - compromised clause and the compromise - ending in written form, has an effect only on parties who have concluded it, and it helps to establish territorial and materials jurisdiction. Where it appears a conflict of competence between a court and an arbitral tribunal, it will be settled by the hierarchically higher court than the ones in conflict.
Procedure on Small Claims in Regulating the Bill of the Code of Civil Procedure
Alexandrina ZAHARIA
Acta Universitatis Danubius : Juridica , 2010,
Abstract: For the smooth operation of the internal market and in order to build a space of freedom, security and justice the Community has adopted, among others, a series of measures that will eliminatethe obstacles standing in the way of civil procedures on judicial cooperation in judicial matters with cross-borders implications in recovering small claims. In this context, CE Regulation no.861 on July, 11th 2007 was adopted by the Parliament and the Council on establishing a European procedure for small claims. Considering the fact that the Regulation expressly provisions that the European procedure on small claims is regulated by the norms of procedural law in the member state in which the procedure is deployed at the claimant’s request, the draft of Code of civil procedure regulated, among the special judicial procedures, the “procedure on small claims”. In the present study we will analyze this form ofspecial judicial procedure and will make some suggestions on the present completion and amendment of the draft, hoping that its authors will take it into consideration, with the purpose of recovering the small claims in due time and the parties will benefit of a fair trial. We consider that in its final form, theregulation of this procedure will correspond to the requirements of the Romanian legislation.
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