OALib Journal期刊

ISSN: 2333-9721




2017 ( 183 )

2016 ( 354 )

2015 ( 6345 )

2014 ( 8351 )


匹配条件: “E Esmati” ,找到相关结果约166904条。
Uterine cervix carcinoma: pathologic characteristics, treatment and follow-up evaluation
Amouzegar Hashemi F,Esmati E,Kalaghchi B
Tehran University Medical Journal , 2008,
Abstract: Background: Carcinoma of the uterine cervix is the sixth most common malignant neoplasm in women. Early stage diagnosis of uterine cervix carcinoma increases the cure rate of disease. Radiotherapy, with or without concurrent chemotherapy, is one of the most effective treatment modality in cervical carcinoma. After radiotherapy, accurate and regular follow-up results in early diagnosis and effective treatment of recurrence. The aim of this study is the assessment of the pathologic characteristics, setting and indications for postoperative radiotherapy and outcome of patients at the last follow-up.Methods: In this retrospective study, we evaluated 346 cases of cervical carcinoma had received radiotherapy in radiation oncology department of the Cancer Institute of Imam Khomeini Hospital, Tehran, Iran, from 1995 to 2001.Results: The age of the study group ranged from 26 to 78 years (mean=50.5, SD=11). Of these patients, 30.4% were in the early stage and 69.6% had advanced stage disease. Squamous cell carcinoma comprised 92.2% of the cases and 6.4% adenocarcinoma. Radical radiotherapy was the most frequent radiotherapy setting and adjuvant radiotherapy (post-op) was the second. A considerable number of patients did not come back for follow-up, and 43.7% were followed for a short time.Conclusion: Accurate presurgical clinical staging and surgical treatment by an expert gynecologic oncologist can reduce expose the patients to risks of two modality treatments (surgery and radiotherapy). According to our results, patients do not pay enough attention to disease follow-up. An acceptable training plan with emphasis on regular follow-up, is recommended.
Concurrent Chemoradiation With Weekly Gemcitabine and Cisplatin in Locally Advanced Cervical Cancer
Amouzegar Hashemi F,Hamed Akbari E,Kalaghchi B,Esmati E
Tehran University Medical Journal , 2011,
Abstract: Background: More than 80 years, the standard treatment of locally advanced cervical cancer was radiotherapy. However, based on several phase III randomized clinical trials in the past decade, concurrent cisplatin-based chemoradiotherapy is the current standard of treatment for this disease. Gemcitabine has potent radiosensitizing properties in preclinical and clinical trials, so it can be utilized simultaneously with radiation.Methods: Thirty Women with untreated invasive squamous-cell carcinoma of the cervix of stage IIB to stage IVA were enrolled in the study in Radiation Oncology department of Imam Khomeini Hospital in Tehran from September 2009 to September 2010. Sixty mg/m2 gemcitabine followed by 35 mg/m2 cisplatin were concurrently administered with radiotherapy to the whole pelvic region on day one of each treatment week for five weeks One and three months after treatment, patients underwent a complete physical examination and MRI to determine the response to treatment.Results: The mean age of the participants was 58.13±11.83 (29-78) years. After 3 months of treatment, 73.3% had complete and 26.7% had partial response to treatment. Grade 3 anemia was seen in 10%, grade 3 thrombocytopenia in 3.3% and grade 3 leukopenia in 10% of the patients.Conclusion: According to the positive results of this study in stage IIB, further phase II and III clinical trials are suggested to evaluate the role of chemoradiation by gemcitabine in advanced cervical cancers.
Neoadjuvant Chemotherapy of Epirobicin, Oxaliplatin, Capecitabine Regimen in Patients with Advanced Gastric Cancer: A Two Year Study
F Samiei,A Maddah Safai,E Esmati,A Alibakhshi
Tehran University Medical Journal , 2012,
Abstract: Background: Gastric cancer is an important health problem across the world. Chemotherapy in combination with local treatment is the standard treatment for locally advanced gastroesophageal junction (EGJ) cancers. The purpose of this study was to evaluate response and tolerability to neoadjuvant regimen combining epirobicin, oxaliplatin and capecitabin (EOX) in locoregionally advanced gastric cancer.Methods: We recruited 28 patients with histologically confirmed advanced gastric or EGJ adenocarcinoma in this study performed in the Cancer Institute of Imam Khomeini Hospital in Tehran, Iran in 2010-2011. Staging workup included chest and abdominal computed tomography (CT) scans, upper gastrointestinal endoscopy, endoscopic ultrasonography (EUS), measurement of carcinoembryonic antigen (CEA), complete blood cell count (CBC), and liver and renal function tests. After three treatment cycles with EOX regimen, we evaluated response to the neoadjuvant chemotherapy by performing endoscopic ultrasonography (EUS) and chest and abdominal CT scans.Results: The mean age of the patients was 56.64±11.08 years (ranging from 37 to 78 years). Most patients were classified as having stage III (98.8%) cancer before chemotherapy while most were classified as stage II (57.14%) after the treatment. Only 28.5% of tumors were resectable before chemotherapy, but 82.1% of them were resectable upon the treatment. 75% of tumors were downstaged after chemotherapy.Conclusion: Regarding the acceptable response and downstaging of tumors and low toxicity of EOX regimen in locoregionally advanced gastric cancer, evaluation of this regimen as a neoadjuvant chemotherapy in larger phase III clinical trials in Iranian patients would be both necessary and logical.
3-Dimentional radiotherapy versus conventional treatment plans for gastric cancer
Aghili M,Moshtaghi M,Samiee F,Esmati E
Tehran University Medical Journal , 2010,
Abstract: "n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: The current standard of adjuvant management for gastric cancer after curative resection based on the results of intergroup 0116 is concurrent chemoradiation. Current guidelines for designing these challenging fields still include two-dimensional simulation with simple AP-PA parallel opposed design. However, the implementation of radiotherapy (RT) remains a concern. Our objective was to compare three-dimensional (3D) techniques to the more commonly used AP-PA technique."n"nMethods: A total of 24 patients with stages II-IV adenocarcinoma of the stomach were treated with adjuvant postoperative chemoradiation with simple AP-PA technique, using Cobalt-60. Total radiation dose was 50.4Gy. Landmark-based fields were simulated to assess PTV coverage. For each patient, three additional radiotherapy treatment plans were generated using three-dimensional (3D) technique. The four treatment plans were then compared for target volume coverage and dose to normal tissues (liver, spinal cord, kidneys) using dose volume histogram (DVH) analysis."n"nResults: The three-dimensional planning techniques provided 10% superior PTV coverage compared to conventional AP-PA fields (p<0.001). Comparative DVHs for the right kidney, left kidney and spinal cord demonstrate lower radiation doses using the 3D planning techniques (p<0.0001), the liver dose is higher (p=0.03), but is still well below liver tolerance."n"nConclusion: Despite the department protocol using conventional planning, 3D radiotherapy provides 10% superior PTV coverage. It is associated with reduced radiation doses to the kidneys and spinal cord compared to AP-PA techniques with the potential to reduce treatment toxicity.
Ebstein-Barr virus antibodies titer before and after radiotherapy in patients with nasopharyngeal carcinoma, Cancer Institute, Imam Khomeini Hospital, 2003 – 2004
F. Amoozegar Hashemi,F.Razi,E.Esmati,M.Sajjadi
Tehran University Medical Journal , 2006,
Abstract: Background: High titer of IgA and IgG are found in the presence of EBV genome in epithelial cells of nasopharyngeal carcinoma. In this survey we evaluated the accuracy of EBV antibodies titers in screening and follow up the patients. Methods: Thirty nasopharyngeal carcinoma patients were followed from 2003 to 2004. Serum EBV antibody levels were measured before and after ( 3 months ) radiotherapy or combined radiotherapy and chemotherapy. Results: More than 77% of patients were seropositive before treatment .The antibodies decreased significantly, 3 months after treatment (p<0.05). Conclusion: This investigation shows the efficiency of serologic methods for screening of high risk people and follow up of patients after treatment, but more complementary studies is needed
Cluster Model of Formation of Subnuclear and Subatomic Objects  [PDF]
E. E. Lin
Journal of Modern Physics (JMP) , 2014, DOI: 10.4236/jmp.2014.53018

The paper describes the development results on one-dimensional (1D) asymptotic model of the formation kinetics for the objects (clusters) of subnuclear (quark) and subatomic (nuclear) matters. A concept of the objects distribution density wave φ(a, t) in space of sizes a lies in the basis for analytical description of the processes under consideration. The proposed formalism makes it possible to describe in an adequate way the final outcomes of the well-known catastrophic phenomena in the world of elementary particles. Mass characteristics of different processes of approach to equilibrium in nuclear reactions are calculated.

ЕЛЕКТРОХ М ЧНИЙ СИНТЕЗ Д ОКСИДУ МАНГАНУ В ПРИСУТНОСТ ОН В Fe2+ ТА Co2+ Electrochemical synthesis of manganese dioxide in the presence of ions Fe2+ and Co2+ Электрохимический синтез диоксида марганца в присутствии ионов Fe2+ и Co2+
Г.В. Сокольський,Н.Д. ?ванова,С.В. ?ванов,E.?. Болдир?в
Proceedings of National Aviation University , 2009,
Abstract: Зразки д оксиду мангану отримано методом анодного осадження з фторвм сних електрол т в на основ сульфату мангану у присутност дом шок он в двовалентних зал за або кобальту. Отриман продукти характеризувалися методами ААС та ДТА. Проанал зовано вплив дом шок он в зал за кобальту на х м чний склад отриманих зразк в Manganese dioxide samples have been prepared by the anode deposition from fluoride containing electrolytes based on manganese sulphate at the presence of additives of iron(II), cobalt(II) ions. Obtained materials were characterised with AAS and DTA. The influence of doping by ions of iron(II) and cobalt(II) on the chemical composition of the samples obtained has been analysed. Образцы диоксида марганца получены методом анодного осаждения из фторсодержащих электролитов на основе сульфата марганца в присутствии примесей ионов двухвалентных железа или кобальта. Полученные продукты характеризовались методами ААС и ДТА. Проанализировано влияние примесей ионов железа и кобальта на химический состав полученных образцов.
Numerical Investigations of a New N-body Simulation Method  [PDF]
E. Vilkoviskij
International Journal of Astronomy and Astrophysics (IJAA) , 2012, DOI: 10.4236/ijaa.2012.23016
Abstract: Numerical investigation of a new similarity method (the Aldar-Kose method) for N-body simulations is described. Using this method we have carried out numerical simulations for two tasks: 1) calculation of the temporal behavior of different physical parameters of active galactic nuclei (AGN) containing a super massive black hole (SMBH), an accretion disk, and a compact stellar cluster; 2) calculation of the stellar capture rate to the central SMBH without accretion disk. The calculations show good perspectives for applications of the similarity method to optimize the evolution model calculations of large stellar systems and of AGN.
Studies on TiO2/Reduced Graphene Oxide Composites as Cathode Materials for Magnesium-Ion Battery  [PDF]
E. Sheha
Graphene (Graphene) , 2014, DOI: 10.4236/graphene.2014.33006

The aim of this work is to introduce a high performance cathode for magnesium-ion batteries. TiO2/reduced graphene oxide (rGO) composites were mixed in ball mill. The samples are charac- terized using XRD and SEM. The spex-milled composites exhibit better electrochemical perfor- mance with higher reversible capacity and excellent cyclability. The excellent electrochemical performance of TiO2/rGO composites is due to their unique structures, which intimately combine the conductive graphene nanosheets network with TiO2 nanoparticles and possess the characteristic parallel channels running along the [010] orientation, which allow easy Mg2+ transport. It was found that layered TiO2 and rGO nanosheets in the composite interlace with each other to form novel sandwich-structured microspheres, which exhibit preferable electrochemical performance in rechargeable Mg batteries.

Linking Regional Science and Urban Economics: Long-Run Interactions among Preferences for Amenities and Public Goods  [PDF]
Philip E. Philip E. Graves
Modern Economy (ME) , 2012, DOI: 10.4236/me.2012.33035
Abstract: The linked nature of long-term patterns of urban deconcentration and regional change (from rustbelt to sunbelt in the U.S., but with similar phenomena increasingly world-wide) is analyzed in a framework that emphasizes heterogeneous human preferences. The focus is on the important interactions that exist between local and regional amenities, whether exogenous or endogenous. The central thesis is that persistent exogenous amenity variation among regions provides an underlying pattern of regional growth and decline. However, inappropriate provision of local public goods in central cities is seen to lead both to non-optimally large levels of suburbanization and to rates of regional change that are also non-optimally large.

Copyright © 2008-2017 Open Access Library. All rights reserved.