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Search Results: 1 - 10 of 10614 matches for " Du Chaohao "
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Design and Performance of Brushless Doubly-fed Machine Based on Wound Rotor with Star-polygon Structure  [PDF]
Chaohao Kan
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.54B015
Abstract: The star-polygon brushless doubly-fed machine (SPBDFM) is a new type of wound-rotor machine and is attractive for variable-speed constant-frequency shaft generation system. The structure of rotor for the machine may be improving the conductor availability of the rotor windings. The kirchhoff laws is employed to illuminate the principle and some combinations of different slots and poles are presented as the examples. Harmonic analysis is also employed to analyze the magnetic motive force (MMF) waveform of rotor winding with the structure of star- polygon. Finally, the results are used to reveal that the SPBDFM is attractive for shaft generation system.
Correlation of SRSF1 and PRMT1 expression with clinical status of pediatric acute lymphoblastic leukemia
Zou Limin,Zhang Han,Du Chaohao,Liu Xiao
Journal of Hematology & Oncology , 2012, DOI: 10.1186/1756-8722-5-42
Abstract: Background Acute lymphoblastic leukemia (ALL) is the most frequently-occurring malignant neoplasm in children, but the pathogenesis of the disease remains unclear. In a microarray assay using samples from 100 children with ALL, SFRS1 was found to be up-regulated. Serine/arginine-rich splicing factor 1 (SRSF1, also termed SF2/ASF), encoded by the SFRS1 gene, had been shown to be a pro-oncoprotein. Our previous study indicated that SRSF1 can be methylated by protein arginine methyltransferase 1 (PRMT1) in vitro; however, the biological function of SRSF1 and PRMT1 in pediatric ALL are presently unknown. Methods Matched, newly diagnosed (ND), complete remission (CR) and relapse (RE) bone marrow samples from 57 patients were collected in order to evaluate the expression patterns of SRSF1 and PRMT1. The potential oncogenic mechanism of SRSF1 and PRMT1 in leukemogenesis was also investigated. Results We identified significant up-regulation of SRSF1 and PRMT1 in the ND samples. Importantly, the expression of SRSF1 and PRMT1 returned to normal levels after CR, but rebounded in the RE samples. Our observation that SRSF1 could predict disease relapse was of particular interest, although the expression patterns of SRSF1 and PRMT1 were independent of the cytogenetic subtypes. In pre-B-cell lines, both SRSF1 and PRMT1 expression could be efficiently attenuated by the clinical chemotherapy agents arabinoside cytosine (Ara-c) or vincristine (VCR). Moreover, SRSF1 and PRMT1 were associated with each other in leukemia cells in vivo. Knock-down of SRSF1 resulted in an increase in early apoptosis, which could be further induced by chemotherapeutics. Conclusions Our results indicate that SRSF1 serves as an anti-apoptotic factor and potentially contributes to leukemogenesis in pediatric ALL patients by cooperating with PRMT1.
Research on Wireless Monitoring Technology of the Well Site Environment  [PDF]
Bo Chen, Chaohao Zhang, Kui Deng, Liang Ge, Pan Hu
Communications and Network (CN) , 2017, DOI: 10.4236/cn.2017.92006
Abstract: Based on the characteristics of wireless communication technology and Wireless Sensor Network, this paper studies the well site environmental monitoring system. The relevant hardware and software of the system are designed to monitor the well site environment, thus preventing downhole accidents. The system uses the wireless ZigBee technology as the transmission mode, and combines the virtual instrument technology to design the upper machine interface. The test results show that the system can monitor the outdoor environment in real time. When the environmental parameters exceed the set value, the corresponding location of the LabVIEW interface will send an alarm.
Association of Six Well-Characterized Polymorphisms in TNF-α and TNF-β Genes with Sarcoidosis: A Meta-Analysis
Yun Feng, Jianping Zhou, Chaohao Gu, Yongjie Ding, Huanying Wan, Lei Ni, Wenquan Niu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080150
Abstract: Backgrounds In this study, we aimed to investigate the association of six well-characterized polymorphisms in tumor necrosis factor alpha and beta (TNF-α and TNF-β) genes with the risk for sarcoidosis via a comprehensive meta-analysis. Methods And Findings The electronic MEDLINE (Ovid) and PubMed databases covering the period from the earliest possible year to June 2013 were searched. Total 13 qualified articles including 1584 patients with sarcoidosis and 2636 controls were recruited. The data were analyzed by RevMan software, and risk estimates were expressed as odds ratios (ORs) and 95% confidence intervals (95% CIs). Analyses of the full data set failed to identify any significant association of TNF-α gene -307A (OR=1.25; 95% CI: 0.98-1.59), -1031C (OR=0.88; 95% CI: 0.71-1.1), -863A (OR=0.89; 95% CI: 0.72-1.11), -238A (OR=0.97; 95% CI: 0.71-1.32), and -857T (OR=1.14; 95% CI: 0.74-1.77) alleles, but a significant association for TNF-β 252A allele (OR=1.65; 95%CI = 1.33-2.04; P<0.00001). Under a random-effects allelic model, there was marginally significant increased risk of sarcoidosis for -307A allele among Caucasians (OR=1.25; 95% CI: 0.96-1.62; P=0.09) but not among Asians (OR=2.12; 95% CI: 0.31-14.27; P=0.44). There was a low probability of publication bias as reflected by the fail-safe number. Conclusions This meta-analysis extended previous findings on the association between the TNF-α and TNF-β genetic polymorphisms and sarcoidosis, by showing that the TNF-β gene A252G polymorphism might be a potential risk factor for the development of sarcoidosis.
Exploration of stable compounds, crystal structures, and superconductivity in the Be-H system
Shuyin Yu,Qingfeng Zeng,Artem R. Oganov,Chaohao Hu,Gilles Frapper,Litong Zhang
Physics , 2014,
Abstract: Using first-principles variable-composition evolutionary methodology, we explored the high-pressure structures of beryllium hydrides between 0 and 400 GPa. We found that BeH$_2$ remains the only stable compound in this pressure range. The pressure-induced transformations are predicted as $Ibam$ $\rightarrow $ $P\bar{3}m1$ $\rightarrow $ $R\bar{3}m$ $ \rightarrow $ $Cmcm$ $ \rightarrow $ $P4/nmm$, which occur at 24, 139, 204 and 349 GPa, respectively. $P\bar{3}m1$ and $R\bar{3}m$ structures are layered polytypes based on close packings of H atoms with Be atoms filling octahedral voids in alternating layers. $Cmcm$ and $P4/nmm$ structures have 3D-networks of strong bonds, but also feature rectanular and squre, respectively, layers of H atoms with short H-H distances. $P\bar{3}m1$ and $R\bar{3}m$ are semiconductors while $Cmcm$ and $P4/nmm$ are metallic. We have explored superconductivity of both metallic phases, and found large electron-phonon coupling parameters of $ \lambda $=0.63 for $Cmcm$ (resulting in a $T_c$ of 32.1-44.1 K) at 250 GPa and $ \lambda $=0.65 for $P4/nmm$ ($T_c$ = 46.1-62.4 K) at 400 GPa. The dependence of $T_c$ on pressure indicates that $T_c$ initially increases to a maximum of 45.1 K for $Cmcm$ at 275 GPa and 97.0 K for $P4/nmm$ at 365 GPa, and then decreases with increasing pressure for both phases.
Cold-State Investigation on a Flame Holder  [PDF]
Yiqing Du
Journal of Power and Energy Engineering (JPEE) , 2013, DOI: 10.4236/jpee.2013.17008

Slitty bluff body is widely used as a high-performance flame holder in power industry. To understand the flame stability mechanism, the evolution of the near wake over a slitty bluff body in cold state was numerically investigated using the renormalization group (RNG) k-ε model at Reynolds number of 470,000. The coherent structure of the near wake was identified by the vortex shedding simulation. To explain the vortex shedding, a mechanism that single vortex of large size suddenly immerses two shear layers was proposed. To quantitatively compare the near wakes at different gap ratio, a vortex shedding character dimension was first proposed. This character dimension has positive correlation with flame stability. Particle-image velocimetry (PIV) measurements in a close wind tunnel were also carried out to confirm the observation from the numerical study. The evidence shows that the numerical results are of good agreement with the cold-state experiments.

Classification of Single Traveling Wave Solutions to the Generalized Strong Nonlinear Boussinesq Equation without Dissipation Terms in P = 1  [PDF]
Xinghua Du
Journal of Applied Mathematics and Physics (JAMP) , 2014, DOI: 10.4236/jamp.2014.23006

By the complete discrimination system for polynomial method, we obtained the classification of single traveling wave solutions to the generalized strong nonlinear Boussinesq equation without dissipation terms in p=1.

New Fixed Point Theorems of Mixed Monotone Operators  [PDF]
Xinsheng Du
Applied Mathematics (AM) , 2014, DOI: 10.4236/am.2014.53037

Mixed monotone operator is an important nonlinear operator. It exists extensively in the research of nonlinear differential and integral equations. Generally, the research of mixed monotone operators in partially ordered Banach spaces requires compactness, continuity or concavity-convexity of the operators. In this paper, without any compact and continuous assumption, we obtain some new existence and uniqueness theorems of positive fixed point of e-concave-convex mixed monotone operators in Banach spaces partially ordered by a cone, which extends the existing corresponding results.

Existence of Positive Solutions to Semipositone Fractional Differential Equations  [PDF]
Xinsheng Du
Applied Mathematics (AM) , 2016, DOI: 10.4236/am.2016.714127
Abstract: In this paper, by means of constructing a special cone, we obtain a sufficient condition for the existence of positive solution to semipositone fractional differential equation.
A Literature Review on Institutional Environment and Technological Innovation  [PDF]
Zhuoyan Du
American Journal of Industrial and Business Management (AJIBM) , 2018, DOI: 10.4236/ajibm.2018.89130
Abstract: This article is a literature review on institutional environment and technology innovation. The author discusses the origin and classification of the institutional environment, has a through understanding of the institutional environment, and examines studies about institutional environment and technology innovation from different perspectives to reach some constructive suggestions to better promote technology innovation.
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