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Universal Design: A Step toward Successful Aging
Kelly Carr,Patricia L. Weir,Dory Azar,Nadia R. Azar
Journal of Aging Research , 2013, DOI: 10.1155/2013/324624
Universal Design: A Step toward Successful Aging
Kelly Carr,Patricia L. Weir,Dory Azar,Nadia R. Azar
Journal of Aging Research , 2013, DOI: 10.1155/2013/324624
Abstract: The concept of aging successfully has become increasingly important as demographics shift towards an aging population. Successful aging has been defined to include (1) a low probability of disease and disease-related disability; (2) a high level of physical and cognitive functioning; and (3) an active engagement in life. The built environment can create opportunities or constraints for seniors to participate in social and productive activities. Universally designed spaces are more easily accessed and used by a spectrum of people without specialized adaptations. Thus, a universally designed environment creates opportunities for older adults to participate in these activities without the stigmatization associated with adapted or accessible designs. Providing older adults with specific universal design options (e.g., lever handle faucets) has the potential to increase the ease of completing activities of daily living, which promotes a continual engagement in life. Literature regarding universal design is promising; however, its theory requires further attention from professionals designing the built environment, evidence of the significance of its application from academics, and the embracement of its core principles from society. Overall, universal design has the potential to provide a stepping stone toward successful aging. 1. Introduction A rise in life expectancy and a decline in fertility rates have created a shift in demographics leading to an aging population [1–4]. Currently, Canada’s population of citizens 65 years of age and older is at a record high (14.8%; [3]). This older adult population has experienced a 14.1% growth in the past five years, with 60–64 year olds experiencing the greatest increase, followed by centenarians [3]. If this trend continues, seniors will account for nearly a quarter of the population by 2036 [4]. At that point, the number of older adults will surpass the number of children, a first in Canadian history [4]. These demographic trends span beyond Canadian borders and have been recognized globally [1]. As a result, successful aging has become an important concept worldwide [5]. Successful aging has been empirically defined to include (1) a low probability of disease and disease-related disability; (2) a high level of physical and cognitive functioning; and (3) an active engagement in life [6, 7]. To some extent, these components represent a hierarchical relationship, as it is suggested that the absence of disease and disability leads to a prolonged maintenance of physical and cognitive functioning, which enables a higher
Allele-Specific Effects on Extracellular Superoxide Dismutase Synthesis and Secretion  [PDF]
Sujung Jun, Ladislav Dory
Journal of Biomedical Science and Engineering (JBiSE) , 2017, DOI: 10.4236/jbise.2017.104011
Abstract: Plasma extracellular superoxide dismutase (ecSOD) concentrations are significantly (2 - 3-fold) higher in 129 mice than in the C57 strain. We reported earlier that the 129 strain carries a different allele of this enzyme, characterized by two amino acid substitutions and a 10 bp deletion in the 3’UTR of the mRNA. One of the substitutions is at the signal peptide cleavage site (position 21) while the other is within the catalytic site. Since the differences in plasma enzyme concentrations persist in congenic mice expressing the different alleles, the differences in plasma concentrations appear to be largely allele-driven and independent of the remainder of the genome. As expected, in vitro translation using rabbit reticulocyte lysate showed no differences in translational efficiency of transcripts and processing of the newly synthesized enzymes. Determinations of the rates of synthesis and secretion of the two isoforms of this enzyme in stably transfected CHO cells clearly demonstrate that the mature 129 variant is synthesized at rates nearly twice those of the wild-type isoform and has an intracellular pool size twice as large. However, both isoforms are secreted at the same fractional rate and have identical intracellular T1/2 as well as similar extent of degradation. These data explain, at least partially, the higher levels of ecSOD in congenic mice expressing the 129 variant, as well as enzyme levels in the 129 strain of mice. In silico calculations support this conclusion and indicate that the aa change at the signal peptide cleavage site (N21D) results in a substantial increase in cleavage probability at this site for the 129 variant. Our results also highlight the importance of signal peptide cleavage in determining steady-state levels of secretory proteins.
La transformation de la Défense : une étape aboutie ?
Raymond Dory
Pyramides : Revue du Centre d'Etudes et de Recherches en Administration Publique , 2012,
Abstract: De par sa situation géographique et son histoire, la Belgique n’a qu’en périodes exceptionnelles considéré la problématique défense comme prioritaire, voire vitale. La planification capacitaire en matière de défense reste un exercice difficile mais pourtant essentiel à la bonne marche de l’outil militaire, lequel pour sa part, se doit d’affronter les défis du moment et ceux du futur. Les plans stratégiques adoptés ces dix dernières années ont profondément modifié le profil opérationnel de la Défense. Ces choix politiques ont engagé et engagent le pays par rapport à ses partenaires et ses alliances de fa on profonde et durable. Une réalisation ne fut-ce que partielle ou incomplète de ces plans a des conséquences très importantes sur la viabilité de l’outil militaire à court et moyen termes et ne peut que déclencher un nouveau cycle de planification stratégique. Les défis qui se posent actuellement à la Défense, que ce soit en matière de personnel ou d’investissements, méritent que les questions de fond soient abordées clairement afin que les choix qui engagent l’avenir soient faits en parfaite connaissance de cause.
Un gong muet au fond de l’homme : A gong of silence inside of a man: a few words in memory of Avrom Sutzkever
Dory Manor
Yod : Revue des études Hébra?ques et Juives , 2011, DOI: 10.4000/yod.653
Abstract: In this homage to one of the greatest Jewish poets of the XXth century, the Israeli poet Dory Manor explains how he discovered the work of Avrom Sutzkever and recounts the personal discussions that he later had with the Yiddish poet. This article is a reflexion on the place of Yiddish literature in Israeli collective imagination as well as about two roads that never met: the one of Israeli culture and the one of this great creator who lived and wrote in Tel-Aviv over the course of sixty-three years. , , 20 “ . – , , – 63 .
Dory Manor
Yod : Revue des études Hébra?ques et Juives , 2011, DOI: 10.4000/yod.378
Abstract: Rencontre avec Sutzkever – Dory Manor , – ( - , – - - ) ( ) . .– , ? – - : . - .– , ? – ...
Evaluating the Practices of Running the MA in Teaching English as a Foreign Language (TEFL) Program in Government Public Universities of South Nation, Nationalities and Peoples Regional State (SNNPRS) of Ethiopia: The Case of Three Universities in the Regional State  [PDF]
Yirgu Asres Dory
Creative Education (CE) , 2019, DOI: 10.4236/ce.2019.1011165
Abstract: The objective of this study was to evaluate the practices of running the MA in Teaching English as a Foreign Language (TEFL) program in government public universities of South Nations, Nationalities and Peoples Regional State (SNNPRS) of Ethiopia. To that end, three universities in the regional state were purposely selected as research sites. Questionnaires, interviews and resource center and thesis defense sessions’ observations were used for gathering relevant data. Experienced TEFL instructors, MA TEFL prospective graduates, English Language and Literature Department heads and TEFL postgraduate coordinators were respondents in the study. Then the data gathered were analyzed using both quantitative and qualitative methods. The findings of the analysis indicate that the departments in the universities face several constraints in the practices of running the program and graduating highly qualified professionals in the field.According to the findings of the study, lack of basic knowledge and skills in the students to pursue the program effectively and lack of effort to develop their knowledge and skills in the area are the major constraints. In addition, lack of facilities and materials, lack of emphasis to quality rather than quantity, lack of commitment in some instructors and shortage of instructors in some universities are constraints that hamper the practices of effectively running the program and producing MA TEFL professionals at the aspired standard.
Waste Related Pollutions and Their Potential Effect on Cancer Incidences in Lebanon  [PDF]
Sahar K. Azar, Safa S. Azar
Journal of Environmental Protection (JEP) , 2016, DOI: 10.4236/jep.2016.76070

Pollution represents an important threat to human health. Waste pollution with its adverse health risks, mainly cancer incidences, is one of the main issues present in Lebanon. Random disposal of wastes is instilling a complex and challenging situation that is affecting the entire population. Here, a comprehensive study is presented along with collected data addressing the correlation between long-term exposure to the different forms of pollution and the chances of being affected with cancer. Lebanon, a country currently facing an extensive garbage crisis, is undergoing alarming surges in pollution rates. Inevitably, these environmental factors become chief elements in influencing disease statistics. It is therefore of urgent importance to seek all solutions possible while raising awareness in order to reduce life threatening risks.

Sedimentary Environments Can Be Changed by Geotechnology (Case Study: A Morphotectonic Idea for Design of Extensive Artificial Bay on the Iranian Plateau)  [PDF]
Mehran Arian, Azar Khodabakhshnezhad
International Journal of Geosciences (IJG) , 2015, DOI: 10.4236/ijg.2015.65039
Abstract: Iranian Plateau between the Lesser Caucasus-Alborz Mountains on the north and Zagros-Makran Ranges on the south has several inter-mountainous depressions which were filled by Quaternary deposits. Geologic evidence implied that, the last marine conditions in some depressions such as the Dasht-e Kavir, Dasht-e Lut and Jazmourian basins, had been changed to land conditions in middle Miocene. Based on shape and elevation of the Dasht-e Kavir, Dasht-e Lut and Jazmourian plains related to sea level and geomorphology of Iranian plateau, three semi-connective artificial lakes can be constructed upon the mentioned plains by consideration of many geologic and geotechnical parameters. These artificial lakes can feed by pumping of water from Oman Sea and form a triple artificial bay which they must be connected together by two gated straits. Therefore, a possible morphotectonic idea with many advantages has suggested that it can be present as an international geotechnologic design. This design has the important environmental impacts which can be changed desert to lake sedimentary basins.
Salt Tectonics in the Southern Iran  [PDF]
Azar Khodabakhshnezhad, Mehran Arian
International Journal of Geosciences (IJG) , 2016, DOI: 10.4236/ijg.2016.73029
Abstract: Based on geographic distribution and geological setting of salt plugs in southern Iran, three salt diapiric provinces have been distinguished. These provinces include the Hormuz, Shiraz-Kazerun and Nyriz-Jahrum sub-basins. There are more than hundred salt plugs which they have been formed and developed in the southern margin of Iran. The salt structures that originated from Hormuz formation in these areas have been restricted and separated from each other for the first time in this paper. Salt diapirism of these provinces has been triggered earlier by Halokinesis in the Zagros and Persian Gulf basins, but it has affected later by tectonic forces, because orientation, shape and position of salt plugs have been followed from convergence regime (especially in the Zagros hinterland). In the other hand, based on our results from salt plugs in Persian Gulf foreland basin and the Zagros hinterland, Halokinesis triggers has been affected more than Halotectonic forces.
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