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Preoperative Versus Postoperative Radiation Therapy in Patients with Soft Tissue Sarcomas
Mohamed Ibrahim El-sayed,Doaa Wadie Maximos,Mostafa El-sayed Abdel-wanis,Amen Hamdy Zaky
Cancer and Clinical Oncology , 2012, DOI: 10.5539/cco.v1n2p36
Abstract: Purpose: To evaluate treatment outcome and to determine whether or not the timing of radiotherapy (RT) was associated with any difference in disease relapse, survival, or incidence of complications in patients with soft tissue sarcomas (STS). Methods: The medical files of 63 patients with a primary, nonmetastatic, STS, treated with surgery and irradiation were evaluated. Data regarding tumor stage, grade, site, dosage and timing of radiotherapy, treatment complications, disease relapse, and disease-free (DFS) and overall survival (OAS) rates were analyzed. Results: The median follow up was 47 months (range; 5-66 months). Four-year OAS and DFS rates were 82.6% and 78.8% respectively. There were significant higher 4-year OAS (p = 0.024) and DFS (p = 0.011) rates in patients with stage I and II diseases than those in patients with stage III disease. On the other hand, there were no significant differences in 4-year OAS (p = 0.83, HR: 0.743, 95% CI: 0.165 to 3.345) and DFS (p = 0.64, HR: 0.74, 95% CI: 0.21 to 2.61) rates between preoperative and postoperative RT patients. Disease relapse for preoperative versus postoperative RT patients was not statistically different (p = 0.41). Wound complications were more frequent in preoperative RT patients (25%) compared to postoperative RT patients (8%) (p = 0.0566 chi-square). Conclusions: Preoperative irradiation has not a positive impact on survival or disease relapse rates, but is associated with high wound complication rate.
Gastrointestinal Stromal Tumors (GISTs), Surgical Management and Clinical Outcome  [PDF]
Ahmed A. S. Salem, Mahoud H. Elshoieby, Doaa W. Maximos, Tarek M. El-Saba
Journal of Cancer Therapy (JCT) , 2016, DOI: 10.4236/jct.2016.74034
Abstract: Introduction: This study investigated the incidence, surgical management and outcome of Gastrointestinal Stromal Tumors (GIST) in Upper Egypt. Methods: A retrospective review of all GIST patients admitted a South Egypt Cancer Institute between Jan. 2010 and Dec. 2015 was conducted. Patients’ demographics, clinical presentation, tumor characteristics, radiological, pathological and immunohistochemical findings, surgical procedures, recurrence and mortality were recorded. Results: A total of 36 GIST patients were identified, stomach was the most common site (27.8%) followed by the small intestine (19.4%) and the large intestine (16.7%). The mean age at time of diagnosis as 52.8 ± 14.4 (ranged from 17 to 76 years). Of these 36 cases, 20 (55.6%) cases were males and 16 (44.4%) cases were females with a ratio of 1.2:1. About 22 cases (61.1%) presented with primary tumors, eight cases (22.2%) had primary tumors and metastases, three cases (8.35) presented with recurrent mass, whereas one case (2.2%) presented either with recurrent mass and metastases or metastases only. The majority of cases (22) had tumorsize >5 cm. Patients were stratified as high, intermediate, low and very low risk (50.6%, 30.6%, 11.1% and 2.8%, respectively). Almost all the cases were surgically managed and 75% were completely resectable. During follow up (average 26.5 months), 22 patients showed complete recovery, 7 had recurrent or metastatic disease and 2 died due to liver metastasis. Conclusion: The incidence of GIST in Upper Egypt is apparently low. Surgical resection is the preferred choice of treatment. The demographic data of GIST patients in South Egypt Cancer institute were similar to those published in the literature. Other prospective studies are required to assess the prognosis and the effect of treatment.
Feasibility of Upfront Debulking Surgery versus Neoadjuvant Chemotherapy Followed by Interval Debulking Surgery for Advanced Ovarian Cancer  [PDF]
Amen Hamdy Zaky, Adel Gabr, Doaa Wadie Maximous, Ahmed A. S. Salem, Amr Farouk Mourad, Haisam Atta, Marwa Ismail
Journal of Cancer Therapy (JCT) , 2018, DOI: 10.4236/jct.2018.92015
Abstract: Background: Inappropriately ovarian cancer cannot be detected until an advanced stage. Radical debulking surgery is considered the cornerstone in the management of advanced ovarian cancer pointing to complete tumor resolution. Unless optimal debulking cannot be achieved, these patients gain little benefit from surgery. Neoadjuvant chemotherapy (NACT) has been recommended as a novel therapeutic modality to a diversity of malignant tumors when the disease is not willing to optimal surgical resection at the time of diagnosis or the patient who unfit for aggressive debulking surgery. The purpose of this study is to compare survival in the patient with advanced ovarian cancer (stage III/IV) underwent primary debulking surgery followed by adjuvant chemotherapy (PDS-ACTR) to those who received neoadjuvant chemotherapy followed by interval debulking surgery (NACT-IDS). Results: Neoadjuvant chemotherapy (NACT-IDS) showed significant complete cytoreduction and decreased in surgical morbidity in comparison to primary debulking surgery (PDS-ACTR). NACT-IDS showed significant improvement in progression-free survival (P-value 0.002) and overall survival (P-value 0.03) in comparison to PDS-ACTR. Response to NACT and residual volume were the two independent prognostic factors for overall survival. Conclusion: NACT-IDS for advanced ovarian cancer (III/IV) resulted in higher frequency of
Nemytskii Operator in the Space of Set-Valued Functions of Bounded φ-Variation  [PDF]
Wadie Aziz
Advances in Pure Mathematics (APM) , 2013, DOI: 10.4236/apm.2013.36072

In this paper we consider the Nemytskii operator, i.e., the composition operator defined by (Nf)(t)=H(t,f(t)), where H is a given set-valued function. It is shown that if the operator N maps the space of functions bounded φ1-variation in the sense of Riesz with respect to the weight function αinto the space of set-valued functions of bounded φ2-variation in the sense of Riesz with respect to the weight, if it is globally Lipschitzian, then it has to be of the form (Nf)(t)=A(t)f(

Uniformly Bounded Set-Valued Composition Operators in the Spaces of Functions of Bounded Variation in the Sense of Riesz  [PDF]
Wadie Aziz, Nelson Merentes
International Journal of Modern Nonlinear Theory and Application (IJMNTA) , 2015, DOI: 10.4236/ijmnta.2015.44017
Abstract: We show that the lateral regularizations of the generator of any uniformly bounded set-valued composition Nemytskij operator acting in the spaces of functions of bounded variation in the sense of Riesz, with nonempty bounded closed and convex values, are an affine function.
Investigate Competitive Intelligence Process: An Exploratory Study in Tunisian Companies
Wadie Nasri
International Business Research , 2011, DOI: 10.5539/ibr.v4n4p62
Abstract: The purpose of this study is to explore the aspects of management of competitive intelligence process in Tunisian companies. This exploratory study was conducted using semi-in-depth interviews with six executives in six companies in Tunisia. The results revealed by this study that the competitive intelligence as a competitive tool is unknown to the vast majority of Tunisian companies. It is not still a formalized stage, but it is in an embryonic way. Second, two most important of information are collected: profiles of potentials customers, and opportunities in new market. Thirdly, for analysing and synthesising information the results indicate that managers knows and uses the majority of methods to analyze competitive information gathered especially in making decisions that fall the marketing department. Fourthly, all companies spend most of their time in collecting information. Although planning what and how to collect information and analysis they receive relatively less attention. This research suggests that overriding influence on successful competitive intelligence process is the existence of a management support, culture and structure, which encourage and develop competitive intelligence activities in companies.
Factors Influencing the Adoption of Internet Banking in Tunisia
Wadie Nasri
International Journal of Business and Management , 2011, DOI: 10.5539/ijbm.v6n8p143
Abstract: The purpose of this paper is to determine those factors that influence the adoption of internet banking services in Tunisia. A theoretical model is provided that conceptualizes and links different factors influencing the adoption of internet banking. A total of 253 respondents in Tunisia were sampled for responding: 95 were internet bank users, 158 were internet bank non users. Factor analyses and regression technique are employed to study the relationship. The results of the model tested clearly that use of internet banking in Tunisia is influenced most strongly by convenience, risk, security and prior internet knowledge. Only information on online banking did not affect intention to use internet banking service in Tunisia. The results also propose that demographic factors impact significantly internet banking behaviour, specifically, occupation and instruction. Finally, this paper suggests that an understanding the factors affecting intention to use internet banking is very important to the practitioners who plan and promote new forms of banking in the current competitive market.
Studies on the Effect of the Capping Materials on the Spherical Gold Nanoparticles Catalytic Activity  [PDF]
Roshdi Seoudi, Doaa A. Said
World Journal of Nano Science and Engineering (WJNSE) , 2011, DOI: 10.4236/wjnse.2011.12008
Abstract: Size-controlled gold nanoparticles (AuNPs) were prepared in the presence of different capping materials (sodium citrate, cetyltrimethylammonium bromide (CTAB), and chitosan). The results obtained suggest that the AuNPs were synthesized with different particle size, which is controlled by changing the molar ratio between sodium citrate, (CTAB), and chitosan to Au (III). The catalytic activities of the AuNPs with different capping materials were studied for 4-nitrophenol reduction by NaBH4 as a model reaction. AuNPs with different capping materials is comparable from the value of the apparent rate constant of 4-nitrophenol reduction (0.6 × 10–3, 1.9 × 10–3, and 2.4 × 10–3 s–1) for sodium citrate, CTAB and chitosan. From the results, it is concluded that, AuNPs catalyzed the electron transfer process between and nitro compounds with all the capping materials used AuNPs capped by chitosan were more active for the reduction than the other two.
Analysis of sectorial plates normally loaded over circular domains. II
Wadie A. Bassali
International Journal of Mathematics and Mathematical Sciences , 1984, DOI: 10.1155/s0161171284000776
Abstract: The method of images is applied to derive exact expressions for the deflections of unlimited wedge-shaped plates the central parts of which are cut, when the plate is simply supported on the radial edges, elastically restrained or free along the circular edge and is acted upon by one of three types of normal loading distributed over the surface of a circular domain. Formulae for the bending and twisting moments along the circular edge are given. Limiting forms of the obtained solutions are considered.
Motivating Salespeople to Contribute to Marketing Intelligence Activities: An Expectancy Theory Approach
Wadie Nasri,Lanouar Charfeddine
International Journal of Marketing Studies , 2012, DOI: 10.5539/ijms.v4n1p168
Abstract: This study was to investigate the motivational factors that may contribute to explain salespeople’s motivation toward marketing intelligence activities. The proposed conceptual model utilizes expectancy theory, a process theory of motivation. Three factors can motivate salesperson to exert effort to collect and transmit information from the field expectancy, instrumentality and valence. The proposed conceptual model provides a manager a better understanding that salespeople will motivated and given amount effort to contribute marketing intelligence activities if he or she will gather good information about competitors or about customers and receive a reward for the information transmitted, which he or she really want to obtain.
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