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Tunguusi fenomeni kajastus evenkide rahvap rimuses ja teaduslikes hüpoteesides
Natalia Dmitrieva,Vitali Romeiko
M?etagused. Hüperajakiri , 2011,
Abstract: On 30 June 1908, a so far unexplained peculiar natural disaster occurred in central Siberia, in the vicinity of the River Podkamennaya Tunguska, the right tributary of Yenisei. As the human memory cannot recall a similar happening, the Tunguska catastropheprovides abundant food for thought even a century later. The investigation of the Tunguska phenomenon commenced only 20 years after the event. The relevant subject matter continues to be exciting for the researchers of today. Yet, the most vivid impression is left on the life and folklore of the Evenks – the indigenous people of the area. The article focuses on how the Tunguska phenomenon has been reflected in the world-view related understandings and scientific hypotheses of the Evenks. In 1995, the area of the Tunguska catastrophe was designated as the national biosphere reserve, including the Leonid Kulik’s research zone, the historical buildingcomplex of the first researchers. Soil investigation, botanical, zoological and ecological research is conducted in the Tunguska reserve, and researchers have put much effort into investigating the development of taiga, and its revival following natural, cosmic and terrestrial catastrophes.
Increased Insensible Water Loss Contributes to Aging Related Dehydration
Natalia I. Dmitrieva, Maurice B. Burg
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0020691
Abstract: Dehydration with aging is attributed to decreased urine concentrating ability and thirst. We further investigated by comparing urine concentration and water balance in 3, 18 and 27 month old mice, consuming equal amounts of water. During water restriction, 3 month old mice concentrate their urine sufficiently to maintain water balance (stable weight). 18 month old mice concentrate their urine as well, but still lose weight (negative water balance). 27 month old mice do not concentrate their urine as well and lose even more weight than the 18 month old mice, indicating a larger negative water balance. Negative water balance in older mice is accompanied by increased vasopressin excretion, providing further evidence of dehydration. All 3 groups maintain water balance while consuming only the water in gel food containing 56% water. However, both older groups excrete a smaller volume of urine of higher osmolality, indicating greater extra urinary water loss. Since their feces also contain less water, the excess water lost by the older mice apparently is through other routes, presumably insensible loss through the respiratory tract and skin. The greater insensible water loss occurs at an earlier age (18 months) than decreased urine concentrating ability (27 months). We propose that insensible water loss through skin and respiration increases with age, making a major contribution to aging related dehydration.
Adaptation to periodic pressure chamber hypoxia and its influence on systolic and diastolic functions in chronic heart failure
Dmitrieva М.К.
Saratov Journal of Medical Scientific Research , 2012,
Abstract: Research objective is to determine the influence of adaptation method to periodic pressure chamber hypoxia on dynamics of systolic and diastolic functions of myocardium in patients with early stages of chronic heart failure. Materials and Methods: 100 men with post-infarction cardiosclerosis at the age of 40-65 years with I and IIA stages and l-ll functional classes (NYHA) of chronic heart failure have been examined. Results: Positive dynamics of systolic and diastolic cardiac functions and other parameters of echocardioscopy under the influence of the hypoxic therapy in comparison with classical physical rehabilitation have been obtained. Furthermore, a more significant effect has been observed in patients with CHF IIA. Conclusion: Improvement in the geometry of the heart has proved that adaptation method to periodic pressure chamber hypoxia could be recommended for rehabilitation of patients with heart failure of early stages.
Sprouted Innervation into Uterine Transplants Contributes to the Development of Hyperalgesia in a Rat Model of Endometriosis
Stacy L. McAllister, Natalia Dmitrieva, Karen J. Berkley
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0031758
Abstract: Endometriosis is an enigmatic painful disorder whose pain symptoms remain difficult to alleviate in large part because the disorder is defined by extrauteral endometrial growths whose contribution to pain is poorly understood. A rat model (ENDO) involves autotransplanting on abdominal arteries uterine segments that grow into vascularized cysts that become innervated with sensory and sympathetic fibers. ENDO rats exhibit vaginal hyperalgesia. We used behavioral, physiological, and immunohistochemical methods to test the hypothesis that cyst innervation contributes to the development of this hyperalgesia after transplant. Rudimentary sensory and sympathetic innervation appeared in the cysts at two weeks, sprouted further and more densely into the cyst wall by four weeks, and matured by six weeks post-transplant. Sensory fibers became abnormally functionally active between two and three weeks post-transplant, remaining active thereafter. Vaginal hyperalgesia became significant between four and five weeks post-transplant, and stabilized after six to eight weeks. Removing cysts before they acquired functional innervation prevented vaginal hyperalgesia from developing, whereas sham cyst removal did not. Thus, abnormally-active innervation of ectopic growths occurs before hyperalgesia develops, supporting the hypothesis. These findings suggest that painful endometriosis can be classified as a mixed inflammatory/neuropathic pain condition, which opens new avenues for pain relief. The findings also have implications beyond endometriosis by suggesting that functionality of any transplanted tissue can be influenced by the innervation it acquires.
Mediator of DNA Damage Checkpoint 1 (MDC1) Contributes to High NaCl-Induced Activation of the Osmoprotective Transcription Factor TonEBP/OREBP
Margarita Kunin,Natalia I. Dmitrieva,Morgan Gallazzini,Rong-Fong Shen,Guanghui Wang,Maurice B. Burg,Joan D. Ferraris
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0012108
Abstract: Hypertonicity, such as induced by high NaCl, increases the activity of the transcription factor TonEBP/OREBP whose target genes increase osmoprotective organic osmolytes and heat shock proteins.
INTOXICACION POR HERBICIDA Y EL USO DE LA TIAMINA. UN ESTUDIO EXPERIMENTAL
Pérez-Pérez Elizabeth,Calderón de Cabrera Lourdes,Rodríguez-Malaver Antonio,Dmitrieva Natalia
Salud, Arte y Cuidado , 2012,
Abstract: Pesticide poisoning, accidental or intentional self-poisoning is a signi cant problem in many parts of the developing world. Paraquat is a compound that has been widely used as a non-selective contact herbicide since 1962. Ingestion of paraquat is a signi cant method ofself-poisoning in parts of Asia, Paci c islands, and Caribbean. Ingestion of large amounts is considered to be uniformly fatal, resulting in death from multi-organ; however, in smaller quantities, paraquat is speci cally taken up into and accumulates in the lung, and the redox cycling and free radical generation triggers a eutrophil-mediated in ammatory response in the lungs which initiates an irreversible brotic process that kills the majority of patientswithin several weeks. In this work, was studied the ability of thiamine to protect against Paraquat (PQ)-induced mortality and oxidative damage in rat liver. The medial lethal dose (LD50) for PQ was 32 mg/kg of body weight within 48 h. When thiamine (100 mg/kg) wasadministrated to PQ-treated rats, mortality was not observed. However, thiamine at 200 mg/kg did not modify mortality. For the oxidative stress study, the liver was obtained 24 h after Q-treatment and thiobarbituric acid reactive ubstances (TBARS) were measured.PQ induced a signi cant increase in TBARS levels and thiamine prevented this increase
Skythen, Amazonen und Futuristen. Der Steppendiskurs der 1910-1920er Jahre und seine heutigen Implikationen
Marina Dmitrieva
Behemoth : a Journal on Civilisation , 2009,
Abstract: Due to the archaeological discovery of Greek and Scythian culture in the south of the Russian Empire in the second half of the 19th century and the scientific exploration of Russia’s own Orient – i.e. the non-European peoples of Siberia, Central Asia, Caucasus and middle-Volga – the Eurasian paradigm became more and more influential among Russian intellectuals and artists. For the adherents of Eurasianism, the steppe, broadly considered as a crossroad between Orient and Occident, embodied their concept of the ‘multiethnic imaginary cultural imperial entity’ as its ultimate legitimation. This article investigates the impact of the perception of the steppe on theorists and artists during the decades of the 1910 and 1920.
Self-presentation of the graduates in employment
Uliya Dmitrieva
Koncept : Scientific and Methodological e-magazine , 2013,
Abstract: The article discusses the need for the formation of self-competence of graduates during the university studies, the content of self-presentation, the views and the main stages of preparation. In order to form graduates of effective communication skills with the employer provides examples of design and preparation of self, as well as a number of recommendations to improve the competitive edge in the job market.
Cross-tail velocity component in the plasma sheet fast flows
N. P. Dmitrieva
Annales Geophysicae (ANGEO) , 2008,
Abstract: The flux transfer in the magnetotail plasma sheet is mainly provided by the tail-aligned fast plasma flows (Bursty Bulk Flows – BBFs). In this paper we study the events with a large cross-tail velocity component, including their occurrence and relationship to the standard BBFs. We found out that a significant part of large Vy events are a subgroup connected with the BBFs propagation. The maximal deviation of the velocity vector from the X direction (about 40–50 degrees, on average) is observed near the BBFs' leading front in the sheath, where the fast flow interacts with surrounding plasma. The average variation of the velocity direction in the vicinity of the BBF resembles a plasma vortex. Our results support the model, in which the BBF represents a polarized, bubble-like flux tube, propagating through the plasma sheet.
Study on the Economic Development of the RF subjects using multivariate model
Olga Angelova,Elena Dmitrieva
Koncept : Scientific and Methodological e-magazine , 2013,
Abstract: The paper proposed and considered multifactorial model of analysis of regions of the Russian Federation. The basis of the idea of building a spatial model was based on the methodology of the modified ABC-analysis, where the main characteristics were considered: the production of goods and services, the dynamics of production and the volume of innovative products and services in the region. The analysis results are of practical importance for the development of strategies to strengthen the unity of economic space and the innovative development of our country.
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