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Search Results: 1 - 10 of 402658 matches for " Ditte M?lgaard-Nielsen "
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Risk reduction before surgery. The role of the primary care provider in preoperative smoking and alcohol cessation
Hanne T?nnesen, Pernille Faurschou, Helge Ralov, Ditte Mlgaard-Nielsen, Grethe Thomas, Vibeke Backer
BMC Health Services Research , 2010, DOI: 10.1186/1472-6963-10-121
Abstract: The design was an exploratory prospective trial. The outcome measured was the number of patients referred to a preoperative smoking and alcohol cessation programme at the same time as being referred for elective surgery by their GP. The participants consisted of 72 high-risk patients who were referred for elective surgery by 47 local participating GPs.The GPs, nurses, and specialists in internal medicine, prehabilitation and surgery developed new clinical practice guidelines based on the literature and interviews with 11 local GPs about the specific barriers for implementing a smoking and alcohol cessation programme. The role of the GP was to be the gatekeeper: identifying daily smokers and hazardous drinkers when referring them to surgery; handing out information on risk reduction; and referring those patients identified to a preoperative smoking and alcohol cessation programme. The role of the hospital was to contact these patients to initiate smoking and alcohol cessation at the hospital out-patient clinic for life-style intervention.The GPs increased their referral to the smoking and alcohol cessation programme from 0% to 10% (7/72 patients) in the study period.The effect of the study was limited in integrating the efforts of primary care providers and hospital surgical departments in increasing the up-take of preoperative smoking and alcohol cessation programmes aimed at smokers and harmful drinkers referred for surgery. New strategies for cooperation between GPs and surgical departments are urgently needed.J.nr. 2005-54-1781 in Danish Data Protection Agency.J.nr. 07 268136 in Scientific Ethical Committee for Copenhagen and Frederiksberg Municipalities.Daily smoking and harmful alcohol intake increases the development of postoperative complications by two to four times [1-4]. The most frequent problems after surgery for smokers are wound and pulmonary complications; for harmful drinkers it is infections, bleeding episodes, cardiopulmonary insufficiency and deat
Rates of induced abortion in Denmark according to age, previous births and previous abortions
Marie-Louise H. Hansen,Ditte Mlgaard-Nielsen,Lisbeth B. Knudsen,Niels Keiding
Demographic Research , 2009,
Abstract: Background: Whereas the effects of various socio-demographic determinants on a woman's risk of having an abortion are relatively well-documented, less attention has been given to the effect of previous abortions and births. Objective: To study the effect of previous abortions and births on Danish women's risk of an abortion, in addition to a number of demographic and personal characteristics. Data and methods: From the Fertility of Women and Couples Dataset we obtained data on the number of live births and induced abortions by year (1981-2001), age (16-39), county of residence and marital status. Logistic regression analysis was used to estimate the influence of the explanatory variables on the probability of having an abortion in a relevant year. Main findings and conclusion: A woman's risk of having an abortion increases with the number of previous births and previous abortions. Some interactions were was found in the way a woman's risk of abortion varies with calendar year, age and parity. The risk of an abortion for women with no children decreases while the risk of an abortion for women with children increases over time. Furthermore, the risk of an abortion decreases with age, but relatively more so for women with children compared to childless women. Trends for teenagers are discussed in a separate section.
Guillain-Barré Syndrome and Adjuvanted Pandemic Influenza A (H1N1) 2009 Vaccines: A Multinational Self-Controlled Case Series in Europe
Silvana Romio, Daniel Weibel, Jeanne P. Dieleman, Henning K. Olberg, Corinne S. de Vries, Cormac Sammon, Nick Andrews, Henrik Svanstr?m, Ditte Mlgaard-Nielsen, Anders Hviid, Maryse Lapeyre-Mestre, Agnès Sommet, Christel Saussier, Anne Castot, Harald Heijbel, Lisen Arnheim-Dahlstr?m, Par Sparen, Mees Mosseveld, Martijn Schuemie, Nicoline van der Maas, Bart C. Jacobs, Tuija Leino, Terhi Kilpi, Jann Storsaeter, Kari Johansen, Piotr Kramarz, Jan Bonhoeffer, Miriam C. J. M. Sturkenboom
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0082222
Abstract: Background The risk of Guillain-Barré syndrome (GBS) following the United States' 1976 swine flu vaccination campaign in the USA led to enhanced active surveillance during the pandemic influenza (A(H1N1)pdm09) immunization campaign. This study aimed to estimate the risk of GBS following influenza A(H1N1)pdm09 vaccination. Methods A self-controlled case series (SCCS) analysis was performed in Denmark, Finland, France, Netherlands, Norway, Sweden, and the United Kingdom. Information was collected according to a common protocol and standardised procedures. Cases classified at levels 1–4a of the Brighton Collaboration case definition were included. The risk window was 42 days starting the day after vaccination. Conditional Poisson regression and pooled random effects models estimated adjusted relative incidences (RI). Pseudo likelihood and vaccinated-only methods addressed the potential contraindication for vaccination following GBS. Results Three hundred and three (303) GBS and Miller Fisher syndrome cases were included. Ninety-nine (99) were exposed to A(H1N1)pdm09 vaccination, which was most frequently adjuvanted (Pandemrix and Focetria). The unadjusted pooled RI for A(H1N1)pdm09 vaccination and GBS was 3.5 (95% Confidence Interval (CI): 2.2–5.5), based on all countries. This lowered to 2.0 (95% CI: 1.2–3.1) after adjustment for calendartime and to 1.9 (95% CI: 1.1–3.2) when we accounted for contra-indications. In a subset (Netherlands, Norway, and United Kingdom) we further adjusted for other confounders and there the RI decreased from 1.7 (adjusted for calendar month) to 1.4 (95% CI: 0.7–2.8), which is the main finding. Conclusion This study illustrates the potential of conducting European collaborative vaccine safety studies. The main, fully adjusted analysis, showed that the RI of GBS was not significantly elevated after influenza A(H1N1)pdm09 vaccination (RI = 1.4 (95% CI: 0.7–2.8). Based on the upper limits of the pooled estimate we can rule out with 95% certainty that the number of excess GBS cases after influenza A(H1N1)pdm09 vaccination would be more than 3 per million vaccinated.
Asger Liebst: Tresserbilleder
Jan Mlgaard
Massekultur & Medier , 1983,
Higgs Critical Exponents and Conformal Bootstrap in Four Dimensions
Oleg Antipin,Esben Mlgaard,Francesco Sannino
Physics , 2014,
Abstract: We investigate relevant properties of composite operators emerging in nonsupersymmetric, four-dimensional gauge-Yukawa theories with interacting conformal fixed points within a precise framework. The theories investigated in this work are structurally similar to the standard model of particle interactions, but differ by developing perturbative interacting fixed points. We investigate the physical properties of the singlet and the adjoint composite operators quadratic in the Higgs field, and discover that the singlet anomalous dimension is substantially larger than the adjoint one. The numerical bootstrap results are then compared to precise four dimensional conformal field theoretical results. To accomplish this, it was necessary to calculate explicitly the crossing symmetry relations for the global symmetry group SU($N$)$\times$SU($N$).
Asháninka medicinal plants: a case study from the native community of Bajo Quimiriki, Junín, Peru
Gaia Luziatelli, Marten S?rensen, Ida Theilade, Per Mlgaard
Journal of Ethnobiology and Ethnomedicine , 2010, DOI: 10.1186/1746-4269-6-21
Abstract: Fieldwork was conducted between July and September 2007. Data were collected through semi-structured interviews, collection of medicinal plants in the homegardens, forest walks, a walk along the river banks, participant observation, informal conversation, cross check through voucher specimens and a focus group interview with children.Four-hundred and two medicinal plants, mainly herbs, were indicated by the informants. The most important families in terms of taxa were Asteraceae, Araceae, Rubiaceae, Euphorbiaceae, Solanaceae and Piperaceae. Eighty-four percent of the medicinal plants were wild and 63% were collected from the forest. Exotics accounted to only 2% of the medicinal plants. Problems related to the dermal system, digestive system, and cultural belief system represented 57% of all the medicinal applications. Some traditional healers received non-indigenous customers, using their knowledge as a source of income. Age and gender were significantly correlated to medicinal plant knowledge. Children knew the medicinal plants almost exclusively by their Spanish names. Sixteen percent of the medicinal plants found in this community were also reported among the Yanesha of the Pasco Region.Despite the vicinity to a city, knowledge on medicinal plants and cultural beliefs are still abundant in this Asháninka Native Community and the medicinal plants are still available in the surroundings. Nevertheless, the use of Spanish names for the medicinal plants and the shift of healing practices towards a source of income with mainly non-indigenous customers, are signs of acculturation. Future studies on quantification of the use of medicinal plants, dynamics of transmission of ethno-medicinal knowledge to the young generations and comparison with available pharmacological data on the most promising medicinal plants are suggested.Peru is one of the twelve most biodiversity rich, or 'mega-diverse', countries of the world. Its combination of latitude and topography creates nume
Harnessing the potential clinical use of medicinal plants as anti-diabetic agents
Campbell-Tofte JI, M lgaard P, Winther K
Botanics: Targets and Therapy , 2012, DOI: http://dx.doi.org/10.2147/BTAT.S17302
Abstract: rnessing the potential clinical use of medicinal plants as anti-diabetic agents Review (1726) Total Article Views Authors: Campbell-Tofte JI, M lgaard P, Winther K Published Date August 2012 Volume 2012:2 Pages 7 - 19 DOI: http://dx.doi.org/10.2147/BTAT.S17302 Received: 24 January 2012 Accepted: 23 April 2012 Published: 22 August 2012 Joan IA Campbell-Tofte,1 Per M lgaard,2 Kaj Winther1 1Department of Clinical Biochemistry, Frederiksberg University Hospital, Frederiksberg, Denmark; 2Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, Denmark Abstract: Diabetes is a metabolic disorder arising from complex interactions between multiple genetic and/or environmental factors. The characteristic high blood sugar levels result from either lack of the hormone insulin (type 1 diabetes, T1D), or because body tissues do not respond to the hormone (type 2 diabetes, T2D). T1D patients currently need exogenous insulin for life, while for T2D patients who do not respond to diet and exercise regimes, oral anti-diabetic drugs (OADs) and sometimes insulin are administered to help keep their blood glucose as normal as possible. As neither the administration of insulin nor OADs is curative, many patients develop tissue degenerative processes that result in life-threatening diabetes comorbidities. Several surveys of medicinal plants used as anti-diabetic agents amongst different peoples have been published. Some of this interest is driven by the ongoing diabetes pandemic coupled with the inadequacies associated with the current state of-the-art care and management of the syndrome. However, there is a huge cleft between traditional medicine and modern (Western) medicine, with the latter understandably demanding meaningful and scientific validation of anecdotal evidence for acceptance of the former. The main problems for clinical evaluation of medicinal plants with promising anti-diabetic properties reside both with the complexity of components of the plant materials and with the lack of full understanding of the diabetes disease etiology. This review is therefore focused on why research activities involving an integration of Systems Biology-based technologies of pharmacogenomics, metabolomics, and bioinformatics with standard clinical data, should be used for cost-effective validation of the safety and anti-diabetic efficacy of promising medicinal plants. The application of such approaches to studying entire mixtures of plant materials will ensure proper elucidation of novel therapies with improved mechanisms of action, as well as facilitate a personalized clinical use of medicinal plants as anti-diabetic agents.
The a theorem for Gauge-Yukawa theories beyond Banks-Zaks
Oleg Antipin,Marc Gillioz,Esben Mlgaard,Francesco Sannino
Physics , 2013, DOI: 10.1103/PhysRevD.87.125017
Abstract: We investigate the a theorem for nonsupersymmetric gauge-Yukawa theories beyond the leading order in perturbation theory. The exploration is first performed in a model-independent manner and then applied to a specific relevant example. Here, a rich fixed point structure appears including the presence of a merging phenomenon between non-trivial fixed points for which the a theorem has not been tested so far.
Birgitte Wistoft: Tyrannisk, men uundv rlig. Telefonen i Danmark f r 1920
Ditte Laursen
MedieKultur : Journal of Media and Communication Research , 2008,
N ede han bussen? Sammenh ngede kommunikationsforl b mellem unge via mobiltelefonen
Ditte Laursen
MedieKultur : Journal of Media and Communication Research , 2007,
Abstract: Denne artikel pr senterer det argument, at unges mobilkommunikation konstruerer sig som l bende kommunikation over tid. Sms-beskeder indg r i sms-dialoger, beskeder og samtaler v ves sammen i sammenh ngende kommunikationsforl b, og samtaler forl ber i serier. Den l bende mobilkommunikation er en situeret pr station og udf res af parterne i f llesskab ved at de konstruerer deres ytringer, s ledes det er muligt for den anden part at forst og behandle ytringerne som forbundet med den foreg ende kommunikation. De l bende, sammenh ngende kommunikationsforl b er organiserende for de unges indbyrdes relationer og for deres hverdagsliv.
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