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Search Results: 1 - 10 of 77 matches for " Dimos Poulikakos "
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Acoustophoretic Waltz: a Contactless Exothermal Reaction
Daniele Foresti,Dimos Poulikakos
Physics , 2013, DOI: 10.1063/1.4893545
Abstract: The fluid dynamics video shows the acoustophoretic handling of a metal sodium chunks and a water droplets before, during and after mixing. The violent exothermal reaction between solid and liquid introduces an additional phase (hydrogen gas). We developed a unique concept for using ultrasound to stably levitated and move along a plane multiple objects in air, independently from their electromagnetic nature and aspect ratio. This contactless material handling can be extended to hazardous, chemical or radioactive samples.
Heat Transfer in Nanofluids
Oronzio Manca,Yogesh Jaluria,Dimos Poulikakos
Advances in Mechanical Engineering , 2010, DOI: 10.1155/2010/380826
Abstract:
Heat Transfer in Nanofluids
Oronzio Manca,Yogesh Jaluria,Dimos Poulikakos
Advances in Mechanical Engineering , 2010, DOI: 10.1155/2010/380826
Abstract:
Heat Transfer in Nanofluids 2012
Yogesh Jaluria,Oronzio Manca,Dimos Poulikakos,Kambiz Vafai
Advances in Mechanical Engineering , 2012, DOI: 10.1155/2012/972973
Abstract:
Heat Transfer in Nanofluids 2012
Yogesh Jaluria,Oronzio Manca,Dimos Poulikakos,Kambiz Vafai,Liqiu Wang
Advances in Mechanical Engineering , 2012, DOI: 10.1155/2012/972973
Abstract:
Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts
Thomas Frauenfelder, Evangelos Boutsianis, Thomas Schertler, Lars Husmann, Sebastian Leschka, Dimos Poulikakos, Borut Marincek, Hatem Alkadhi
BioMedical Engineering OnLine , 2007, DOI: 10.1186/1475-925x-6-35
Abstract: One patient with saphenous CABG and end-to-side anastomosis and one patient with saphenous CABG and side-to-side anastomosis underwent 16-detector row computed tomography (CT). Geometric models of coronary arteries and bypasses were reconstructed for CFD analysis. Blood flow was considered pulsatile, laminar, incompressible and Newtonian. Peri-anastomotic mass flow and WSS were quantified and flow patterns visualized.CFD analysis based on in-vivo CT coronary angiography data was feasible in both patients. For both types of CABG, flow patterns were characterized by a retrograde flow into the native coronary artery. WSS variations were found in both anastomoses types, with highest WSS values at the heel and lowest WSS values at the floor of the end-to-side anastomosis. In contrast, the highest WSS values of the side-to-side anastomosis configuration were found in stenotic vessel segments and not in the close vicinity of the anastomosis. Flow stagnation zones were found in end-to-side but not in side-to-side anastomosis, the latter also demonstrating a smoother stream division throughout the cardiac cycle.CFD analysis of venous CABG based on in-vivo CT datasets in patients was feasible producing qualitative and quantitative information on mass flow and WSS. Differences were found between the two types of anastomosis warranting further systematic application of the presented methodology on multiple patient datasets.Coronary artery bypass graft (CABG) surgery represents the standard treatment of advanced coronary artery disease (CAD). Since the pioneering work of Favaloro [1], various grafts and different surgical techniques have been investigated. Regarding anastomoses, two major types exist to connect the graft to the coronary artery, i.e. by using an end-to-side or a side-to-side anastomosis. Although the latter has been reported to provide some advantages over individual grafting with end-to-side anastomosis [2-4], the sequential grafting technique has often been cri
What am I? Supercooled droplet or ice?
Carlo Antonini,Adrian Mularczyk,Tanmoy Maitra,Manish K. Tiwari,Dimos Poulikakos
Physics , 2013,
Abstract: In this fluid dynamics video we show the trick played by a supercooled liquid water drop against a superhydrophobic surface. The water drop shows a double personality, impacting onto the surface the first time while still in the liquid state, and then re-impacting as a frozen ice crystal.
Compound Ex Vivo and In Silico Method for Hemodynamic Analysis of Stented Arteries
Farhad Rikhtegar, Fernando Pacheco, Christophe Wyss, Kathryn S. Stok, Heng Ge, Ryan J. Choo, Aldo Ferrari, Dimos Poulikakos, Ralph Müller, Vartan Kurtcuoglu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0058147
Abstract: Hemodynamic factors such as low wall shear stress have been shown to influence endothelial healing and atherogenesis in stent-free vessels. However, in stented vessels, a reliable quantitative analysis of such relations has not been possible due to the lack of a suitable method for the accurate acquisition of blood flow. The objective of this work was to develop a method for the precise reconstruction of hemodynamics and quantification of wall shear stress in stented vessels. We have developed such a method that can be applied to vessels stented in or ex vivo and processed ex vivo. Here we stented the coronary arteries of ex vivo porcine hearts, performed vascular corrosion casting, acquired the vessel geometry using micro-computed tomography and reconstructed blood flow and shear stress using computational fluid dynamics. The method yields accurate local flow information through anatomic fidelity, capturing in detail the stent geometry, arterial tissue prolapse, radial and axial arterial deformation as well as strut malapposition. This novel compound method may serve as a unique tool for spatially resolved analysis of the relationship between hemodynamic factors and vascular biology. It can further be employed to optimize stent design and stenting strategies.
On the permeability of fractal tube bundles
I. Zinovik,D. Poulikakos
Physics , 2011,
Abstract: The permeability of a porous medium is strongly affected by its local geometry and connectivity, the size distribution of the solid inclusions and the pores available for flow. Since direct measurements of the permeability are time consuming and require experiments that are not always possible, the reliable theoretical assessment of the permeability based on the medium structural characteristics alone is of importance. When the porosity approaches unity, the permeability-porosity relationships represented by the Kozeny-Carman equations and Archie's law predict that permeability tends to infinity and thus they yield unrealistic results if specific area of the porous media does not tend to zero. The goal of this paper is an evaluation of the relationships between porosity and permeability for a set of fractal models with porosity approaching unity and a finite permeability. It is shown that the tube bundles generated by finite iterations of the corresponding geometric fractals can be used to model porous media where the permeability-porosity relationships are derived analytically. Several examples of the tube bundles are constructed and relevance of the derived permeability-porosity relationships is discussed in connection with the permeability measurements of highly porous metal foams reported in the literature.
New insights into the mechanisms of bisphosphonates action
Efstathia Tsetsenekou, Dimos Kalyvas
Hellenic Archives of Oral and Maxillofacial Surgery , 2010,
Abstract: Bisphosphonates are nowdays the most common class of drugs used to prevent and treat skeletal disorders related to diseases resulting from increased osteoclastic activity, such as multiple myeloma, metastatic cancer, Paget’s disease, as well as for management of osteoporosis. The use of bisphosphonates as promoters of osseointegration for dental implants is currently being investigated. Their application in joint arthroplasty for optimizing long-term success has also produced promising results. However, the knowledge of their mechanisms of action is constantly being enriched or modified. Each bisphosphonate has its own unique profile regarding its binding affinity with bone mineral and intracellular biochemical activities. The supposed relation between their pharmacological differences and clinical effectiveness has not yet been confirmed. It appears that the major difference between bisphosphonates arises from their biochemical targets (after their cellular uptake). The aim of this study is to report new insights into the mechanisms of action of bisphosphonates.
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