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Search Results: 1 - 10 of 15110 matches for " Diego Bruno "
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The BONSAI Approach Applied to Small-Medium Enterprises
Diego Bruno
IBIMA Business Review , 2011,
Abstract: In this paper, we describe the BONSAI approach and how Small-Medium Enterprises can take advantage of it. BONSAI consists of a set of behaviors, best-practices and guidelines which help professionals to develop better software. Conceived as an iterative and incremental process, it helps to integrate the software development process with the upper processes of the enterprise taking advantage of Business Process Management techniques. It brings to Small-Medium Enterprises the capability to support continuous changes helping them to mitigate and assess the risks involved.
A CERTID O DE ANTECEDENTES REFORMULADA E A PRECIS O NOS PROCEDIMENTOS PENAIS
Bruno Sitta Giacomini,Diego Prezzi Santos
Nómadas , 2009,
Abstract: O presente estudo buscou elucidar como a recente Lei 11.971/09 determina a emiss o das certid es de antecedentes criminais mais precisas, garantindo, juntamente com o teor da Súmula Vinculante 14, a possibilidade a possibilidade de defesa e exclus o de hom nimos em Inquérito e processo criminal.
Intense Rainfall in S?o Carlos/SP: Determination of Threshold Values Using Climate Indices and Their Spatio-Temporal Repercussion  [PDF]
Rafael Grecco Sanches, Gustavo Zen de Figueiredo Neves, Bruno Cesar dos Santos, Maurício Sanches Duarte Silva, Diego Narciso Buarque Pereira, Adriano Rogério Bruno Tech
American Journal of Climate Change (AJCC) , 2018, DOI: 10.4236/ajcc.2018.73023
Abstract: The intense and extreme rains in southeastern Brazil are spatially and temporally dynamic, corroborating their substantial complexity regarding understanding and associations. Therefore, the present study aimed at determining threshold values for events of intense and extreme rainfall in the region of São Carlos/SP using a climatic index, as well as temporal and spatial observations. The RClimdex script, Rnn index, and the detection of outliers were employed in order to mark and establish intense and extreme rainfall thresholds for the region. Values of 10 mm and 20 mm of rain were considered typical and of greater recurrence, and their incidence over a period of 24 hours did not necessarily denote intense events. In turn, values of 35, 46, and 60 mm indicate pluviometric rates that impact on significant disasters, as verified in the IPMET/UNESP natural disasters database. It is important to emphasize that values below 60 mm of daily rainfall may also indicate disaster contexts. However, they do not exclude the necessity to verify the intensity, duration, and frequency of intense rain events, and can delineate thresholds for territorial management organizations in their planning.
Decision Trees as a Tool to Select Sugarcane Families  [PDF]
Luiz A. Peternelli, Diego P. Bernardes, Bruno P. Brasileiro, Marcio H.P. Barbosa, Raphael H. T. Silva
American Journal of Plant Sciences (AJPS) , 2018, DOI: 10.4236/ajps.2018.92018
Abstract: New strategies are required in the sugarcane selection process to optimize the genetic gains in breeding programs. Conventional selection strategies have the disadvantage of requiring the weighing of all the plants in a plot or a sample of stalks and the counting of the number of stalks in all the experimental plots, which cannot always be performed because more than 200,000 genotypes routinely comprise the first test phase (T1) of most sugarcane breeding programs. One way to circumvent this problem is to use decision trees to rank the yield components (the stalk height, the stalk diameter and the number of stalks) and to subsequently use this categorization to select the best families for a specific trait. The objective of this study was to evaluate the categorization of yield components using the classification and regression tree (CART) algorithm as a family selection strategy by comparing the performance of CART with those of conventional methods that require the weighing of stalks, such as the best linear unbiased prediction (BLUP) with sequential (BLUPS) or individual simulated (BLUPIS) procedures. Data from five experiments performed in May 2007 in a randomized block design were analyzed. Each experiment consisted of five blocks, 22 families and two controls (commercial varieties). CART effectively defined the classes of the yield components and selected the best families with an accuracy of 74% compared to BLUPS and BLUPIS. Families with at least 11 stalks per linear meter of furrow resulted in productivities that were above the average productivity of the commercial varieties used in this study and are, therefore, recommended for selection.
Fibromatosis orbitaria solitaria: reporte de caso
Docampo,Jorge; Santoro,Diego; Bruno,Claudio; Morales,Carlos;
Revista argentina de radiolog?-a , 2010,
Abstract: solitary fibrous tumor of the orbit. case report we report on a 4-year-old female patient with solitary fibrous tumor of the orbit, who presented with right eye ptosis and loss of visual sharpness. computed tomography (ct) scan, ultrasonography (us) and magnetic resonance imaging (mri) showed an intraconal mass lesion involving the extrinsic orbit muscles, leaving a depression on the aptic nerve.
Caracterización morfológica y molecular de la línea celular mecencefálica CAD
Carolina León,Bruno Benítez,Diego Forero,Gonzalo Arboleda
Iatreia , 2005,
Abstract: La línea celular murina CAD es un subclón de la línea catecolaminérgica Cath.a., que como su línea parental expresa una varidad de marcadores neuronales.
Fibromatosis orbitaria solitaria: reporte de caso
Jorge Docampo,Diego Santoro,Claudio Bruno,Carlos Morales
Revista Argentina de Radiología , 2010,
Abstract: Se reporta un caso de fibromatosis orbitaria solitaria en una paciente de sexo femenino de 4 a os de edad, la que acudió a consulta por proptosis derecha y pérdida de la agudeza visual. Por tomografía computada (TC), ecografía y resonancia magnética (RM) se identificó una masa intraconal que comprometía a los músculos extrínsecos de la órbita y hacía impronta sobre el nervio óptico. Solitary fibrous tumor of the orbit. Case report We report on a 4-year-old female patient with solitary fibrous tumor of the orbit, who presented with right eye ptosis and loss of visual sharpness. Computed tomography (CT) scan, ultrasonography (US) and magnetic resonance imaging (MRI) showed an intraconal mass lesion involving the extrinsic orbit muscles, leaving a depression on the aptic nerve.
Angioplastia coronaria en la República Argentina. Comparación de los resultados en la fase hospitalaria de los estudios CONAREC V y CONAREC XIV
Bruno Linetzky,Ricardo A. Sarmiento,Juan Barceló,Diego Lowenstein
Revista Argentina de Cardiología , 2007,
Abstract: La angioplastia coronaria (ATC) es una técnica para el tratamiento de la enfermedad coronaria que se encuentra en constante evolución. El registro CONAREC V relevó características de pacientes sometidos a angioplastia durante el a o 1996. Diez a os después publicamos los resultados del estudio CONAREC XIV. ObjetivoComparar las características demográficas y clínicas, la utilización de dispositivos y de pruebas funcionales, los resultados y las complicaciones de la ATC en el estudio CONAREC V con el estudio CONAREC XIV. Material y métodosSe unificaron las bases de datos de ambos protocolos. Se compararon las variables continuas por medio de la prueba de la t y las categóricas con la prueba de chi cuadrado. Se construyó un modelo de regresión logística para determinar si disminuyó la tasa de complicaciones en el a o 2005, ajustando por confundidores.ResultadosLos pacientes del CONAREC XIV fueron más a osos (62,8 ± 10,8 versus 60,6 ± 10,9 a os), con mayor prevalencia de hipertensión arterial (72,4% versus 61,3%; p < 0,001) y diabetes (19,2% versus 16,9%; p = 0,017) y menor de tabaquismo (22% versus 38%; p < 0,001); presentaron enfermedad de tres vasos (20,2% versus 14,8%; p < 0,001) y ATC de más de un vaso con mayor frecuencia (25,3% versus 11,8%; p < 0,001); se incrementaron el uso de stents (94,5% versus 48%; p < 0,001) y la indicación por cuadros estables (36,3% versus 18,2%; p < 0,001). El uso de pruebas funcionales en este contexto fue menor en el a o 2005 (54% versus 65%; p < 0,001).En pacientes con infarto agudo de miocardio, en el CONAREC XIV se observó una prevalencia menor de infarto anterior (46% versus 57,8%; p < 0,005) y de shock cardiogénico (7,3% versus 13,5%; p = 0,017). La tasa de complicaciones mayores fue menor en el último protocolo, CONAREC XIV (3,1% versus 8,9%; p < 0,001). En el modelo multivariado, pertenecer al último estudio disminuyó el riesgo de padecer eventos (OR 0,41, IC 95% 0,26-0,64; p < 0,001).ConclusionesEn el relevamiento del a o 2005, la ATC se realizó en pacientes con más factores de riesgo y mayor compromiso angiográfico. Se incrementó la indicación en cuadros estables. La tasa de complicaciones, como infarto, cirugía y muerte, se redujo en forma independiente.
Application of Terrestrial and Aerial Gravimetry in the Pimenta Bueno Graben, Brazil  [PDF]
Hans Schmidt Santos, Diego Moreno Monteiro, Bruno Leite Teixeira
Open Access Library Journal (OALib Journal) , 2014, DOI: 10.4236/oalib.1100922
Abstract: This paper presents an application of the gravimetric method using terrestrial and aerial data collected in one sector of the Parecis Basin, Brazil. The data received latitude and elevation corrections and also the Eotvos correction in the aerial survey case. Maps of Free-Air anomaly and Bouguer anomaly were obtained. These maps allowed us to identify the Pimenta Bueno Graben, which is an attractive region for oil and gas prospecting. Finally, the maps were compared and correlated to tectonic domains of the Pimenta Bueno Graben region.
Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
Fernanda Andrade,Francisco Goycoolea,Diego A. Chiappetta,José das Neves,Alejandro Sosnik,Bruno Sarmento
International Journal of Carbohydrate Chemistry , 2011, DOI: 10.1155/2011/865704
Abstract: Recently, much attention has been given to pulmonary drug delivery by means of nanosized systems to treat both local and systemic diseases. Among the different materials used for the production of nanocarriers, chitosan enjoys high popularity due to its inherent characteristics such as biocompatibility, biodegradability, and mucoadhesion, among others. Through the modification of chitosan chemical structure, either by the addition of new chemical groups or by the functionalization with ligands, it is possible to obtain derivatives with advantageous and specific characteristics for pulmonary administration. In this paper, we discuss the advantages of using chitosan for nanotechnology-based pulmonary delivery of drugs and summarize the most recent and promising modifications performed to the chitosan molecule in order to improve its characteristics. 1. Introduction Alongside the successful market launch of different products over the last decades, a continuous effort to formulate delivery systems for the pulmonary administration of a wide variety of drugs has been extensively described in the literature [1, 2]. The particular anatomical, physiological, and pathophysiological features of the respiratory tract pose enormous challenges that need to be overcome in order to obtain effective lung deposition, uniform distribution, in loco retention (main challenge is to circumvent mucocilliary clearance), and stability (particularly to enzymatic degradation) of therapeutic agents [1, 3]. Nevertheless, particular attention has been dedicated not only to drugs themselves but also to excipients required to improve the bioavailability of drugs administered pulmonarily. In this context, excipients that could transiently enhance the absorption of drugs are on the spot. Chitosan, a polysaccharide with structural characteristics similar to glucosamines and obtained by the alkaline deacetylation of chitin, derived from the exoskeleton of crustaceans, is one of such appealing excipients. The safety and tolerability of chitosan are synergistic characteristics towards its application in drug delivery by different administration routes. Despite the natural properties, some drawbacks are associated with the poor solubility at physiologic pH and the passive targeting effect. Thus, chemical modifications of chitosan by conjugating various functional groups allow the control of the hydrophilicity and the solubility at neutral and basic pH and open new opportunities to expand the application of this biopolymer. In this paper, we revise some of the most recent and promising
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