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Search Results: 1 - 10 of 224033 matches for " Devendra R. Malaviya "
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Genetic Diversity and Lineage Based on SSR Markers of Two Genomic Resources among Trifolium Collections Held within the Australian Pastures Genebank  [PDF]
Devendra R. Malaviya, Harsh Raman, Brian S. Dear, Rosy Raman, Ajoy K. Roy, Pankaj Kaushal, Amaresh Chandra, Steve J. Hughes
Open Journal of Genetics (OJGen) , 2019, DOI: 10.4236/ojgen.2019.91001
Abstract: Trifolium alexandrinum, an important forage legume, suffers from narrow genetic base. The present investigation was envisaged to reveal the inter- and intra-species genetic diversity and lineage among 64 accessions, representing a global collection, of T. alexandrinum; it’s two probable progenitor species (T. salmoneum and T. subterraneum) and the three genetically distant species (T. repens, T. vesiculosum, T. michelianum). A set of Simple Sequence Repeats (SSR) primer-pairs developed from T. alexandrinum have shown to amplify alleles across the species under study, suggesting utility of the newly developed resource for assessing molecular diversity among Trifolium species. These SSRs markers together with previously reported SSRs, derived from T. repens, enabled to reveal high intra-species polymorphism in T. alexandrinum and successfully discriminate different species investigated in this study. The diverse accessions determined herein provide a superior resource for further breeding
Drug adherence to biologic DMARDS with a special emphasis on the benefits of subcutaneous abatacept
Malaviya AP, st r AJ
Patient Preference and Adherence , 2012, DOI: http://dx.doi.org/10.2147/PPA.S23786
Abstract: ug adherence to biologic DMARDS with a special emphasis on the benefits of subcutaneous abatacept Review (1402) Total Article Views Authors: Malaviya AP, st r AJ Published Date August 2012 Volume 2012:6 Pages 589 - 596 DOI: http://dx.doi.org/10.2147/PPA.S23786 Received: 23 March 2012 Accepted: 28 April 2012 Published: 15 August 2012 Anshuman P Malaviya,1 Andrew JK st r1,2 1Rheumatology Clinical Research Unit, Addenbrooke's Hospital, Cambridge, UK; 2School of Clinical Medicine, University of Cambridge, Cambridge, UK Abstract: Major advances in drug development have led to the introduction of biologic disease-modifying drugs for the treatment of rheumatoid arthritis, which has resulted in unprecedented improvement in outcomes for many patients. These agents have been found to be effective in reducing clinical signs and symptoms, improving radiological damage, quality of life, and functionality, and have also been found to have an acceptable safety profile. Despite this, drug adherence is unknown, which has huge health care and health-economic implications. Local and national guidelines exist for the use of biologics; however, its varied use is widespread. Although this may in part reflect differences in prescribing behavior, patient preference plays a key role. In this review we will explore the factors that contribute to patient preference for, and adherence to, biologic therapy for rheumatoid arthritis with emphasis on the subcutaneous preparation of abatacept, a T-cell costimulatory molecule blocker. Overall, subcutaneous administration is preferred by patients and this may well improve drug adherence.
On Moment Generating Function of Generalized Order Statistics from Erlang-Truncated Exponential Distribution  [PDF]
Anamika Kulshrestha, R. U. Khan, Devendra Kumar
Open Journal of Statistics (OJS) , 2012, DOI: 10.4236/ojs.2012.25071
Abstract: In this paper explicit expressions and some recurrence relations are derived for marginal and joint moment generating functions of generalized order statistics from Erlang-truncated exponential distribution. The results for k-th record values and order statistics are deduced from the relations derived. Further, a characterizing result of this distribution on using the conditional expectation of function of generalized order statistics is discussed.
Drug adherence to biologic DMARDS with a special emphasis on the benefits of subcutaneous abatacept
Malaviya AP,Östör AJ
Patient Preference and Adherence , 2012,
Abstract: Anshuman P Malaviya,1 Andrew JK st r1,21Rheumatology Clinical Research Unit, Addenbrooke's Hospital, Cambridge, UK; 2School of Clinical Medicine, University of Cambridge, Cambridge, UKAbstract: Major advances in drug development have led to the introduction of biologic disease-modifying drugs for the treatment of rheumatoid arthritis, which has resulted in unprecedented improvement in outcomes for many patients. These agents have been found to be effective in reducing clinical signs and symptoms, improving radiological damage, quality of life, and functionality, and have also been found to have an acceptable safety profile. Despite this, drug adherence is unknown, which has huge health care and health-economic implications. Local and national guidelines exist for the use of biologics; however, its varied use is widespread. Although this may in part reflect differences in prescribing behavior, patient preference plays a key role. In this review we will explore the factors that contribute to patient preference for, and adherence to, biologic therapy for rheumatoid arthritis with emphasis on the subcutaneous preparation of abatacept, a T-cell costimulatory molecule blocker. Overall, subcutaneous administration is preferred by patients and this may well improve drug adherence.Keywords: subcutaneous administration, self-injectable, abatacept, rheumatoid arthritis, preference, adherence, compliance, biologic DMARD
Community Based Integrated Malaria Control with Reference to Involvement of Social Forestry Activities: An Experience
Malaviya VS,Kant R,Pant CS,Srivastava HC
Indian Journal of Community Medicine , 2006,
Abstract:
Balancing tension in transferred slips in some dynamic procedures for claw finger correction
Malaviya G
Indian Journal of Plastic Surgery , 2005,
Abstract: The adjustment of tension on the tendon slips which are being inserted to correct finger clawing, is the critical step in claw finger correction procedures. Several methods have been described in literature but ultimately every thing boils down to the experience of the operating surgeon who has to make decisions on the operating table. Attempt is being made to translate this experience (an abstract noun) in to words to help make life easier for the surgeons who are venturing into the field of corrective surgery and do not have enough experience to back them.
Molecular Characterization of Pseudomonas spp. Isolated from Root Nodules of Various Leguminous Plants of Shekhawati Region, Rajasthan, India  [PDF]
Sakshi Issar, Saroj Sharma, Devendra Kumar Choudhary, Hemant Kumar Gautam, R. K. Gaur
American Journal of Plant Sciences (AJPS) , 2012, DOI: 10.4236/ajps.2012.31005
Abstract: Plant growth promontory Pseudomonas strains were isolated from root nodules of five plant species, viz., Trifolium pretense, Cicer arietinum, Amaranthus polygamus, Vigna mungo, and Trigonella foenum; that plants were denizen of Shekhawati region of Rajasthan. A total of 8 bacterial isolates were evaluated for growth promotion using PGP properties. Partial 16S rDNA sequencing data showed that these 8 bacterial isolates belonged to genus Pseudomonas. MEGA 4.0.2, software was used to construct a neighbor joining tree by employing boot strap method. Result exhibited significant diversity among recovered Pseudomonas strains.
SWAT Model Prediction of Phosphorus Loading in a South Carolina Karst Watershed with a Downstream Embayment  [PDF]
Devendra M. Amatya, Manoj K. Jha, Thomas M. Williams, Amy E. Edwards, Daniel R. Hitchcock
Journal of Environmental Protection (JEP) , 2013, DOI: 10.4236/jep.2013.47A010
Abstract:

The SWAT model was used to predict total phosphorus (TP) loadings for a 1555-ha karst watershed—Chapel Branch Creek (CBC)—which drains to a lake via a reservoir-like embayment (R-E). The model was first tested for monthly streamflow predictions from tributaries draining three potential source areas as well as the downstream R-E, followed by TP loadings using data collected March 2007-October 2009. Source areas included 1) a golf course that received applied wastewater, 2) urban areas, highway, and some agricultural lands, and 3) a cave spring draining a second golf course along with agricultural and forested areas, including a substantial contribution of subsurface water via karst connectivity. SWAT predictions of mean monthly TP loadings at the first two source outlets were deemed reasonable. However, the predictions at the cave spring outlet were somewhat poorer, likely due to diffuse variable groundwater flow from an unknown drainage area larger than the actual surface watershed, for which monthly subsurface flow was represented as a point source during simulations. Further testing of the SWAT model to predict monthly TP loadings at the R-E, modeled as a completely mixed system, resulted in their over-predictions most of the months, except when high lake water levels occurred. The mean monthly and annual flows were calibrated to acceptable limits with the exception of flow over-prediction when lake levels were low and surface water from tributaries disappeared into karst connections. The discrepancy in TP load predictions was attributed primarily to the use of limited monthly TP data collected during baseflow in the embayment. However, for the 22-month period, over-prediction of mean monthly TP load (34.6 kg/mo) by 13% compared to measured load (30.6 kg/mo) in the embayment was deemed acceptable. Simulated results showed a 42% reduction in TP load due to settling in the embayment.

Crystallization Behavior and Microstructural Analysis of Lead-Rich () Glass Ceramics Containing 1mole
C. R. Gautam,Devendra Kumar,Om Parkash
Advances in Materials Science and Engineering , 2011, DOI: 10.1155/2011/402376
Abstract: Solid solution of perovskite Pb,SrTiO3 in Pb-rich composition can be crystallized in borosilicate glassy matrix. The addition of rare earth and transition metal oxides is known to influence the crystallization behavior and surface morphology of perovskite crystallites in glassy matrix. In the present paper, the glasses in the lead-rich system 64[(PbxSr1-x)·TiO3]-25[2SiO2·B2O3]-5[K2O]-5[BaO] (1≤≤0.5) with the addition of 1 mol % La2O3 were prepared to study its effect on their crystallization behavior. Differential thermal analysis (DTA) patterns show one or more exothermic crystallization sharp peaks, which shift towards higher temperature with increasing concentration of SrO. The glasses were subjected to various heat-treatment schedules for crystallization. X-ray diffraction analysis of these glass ceramic samples shows that major crystalline phase of the entire glass ceramic sample with ≥0.5 was found to have tetragonal structure similar to PbTiO3 ceramic, and addition of La2O3 enhances the crystallization of the perovskite phase and retards the crystallization of minor phases.
Crystallization Behavior and Microstructural Analysis of Strontium Rich () Glass Ceramics in Presence of
C. R. Gautam,Devendra Kumar,Om Parkash
Advances in Materials Science and Engineering , 2011, DOI: 10.1155/2011/747346
Abstract: Crystallization and microstructural behavior of various strontium-rich glass ceramics in the system 65[(PbxSr1−x)TiO3]-24[2SiO2?B2O3]-5[BaO]-5[K2O]-1[La2O3] (0.0≤≤0.4) with addition of 1% La2O3 have been investigated. The addition of La2O3 has been found to play an important role in crystallization of perovskite (Pb,Sr)TiO3 as a solid solution phase. Also, it causes a change in the surface morphology of the fined crystallites of the major phase. Differential thermal analysis (DTA) shows only one exothermic crystallization peak, which shifts towards higher temperature with increasing amount of strontium oxide. Glasses were subjected to various heat treatment schedules for the crystallization. Very good crystallization of strontium-rich glass compositions is observed. X-ray diffraction studies confirm that cubic perovskite lead strontium titanate crystallizes as major phase. Lattice parameter decreases with increasing strontium content similar to lead strontium titanate ceramics. Uniform and interconnected crystallites are dispersed in glassy matrix.
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