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Search Results: 1 - 10 of 325352 matches for " Deepthi S "
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Dry Powder Inhalers - An Overview
M. Alagusundaram,N. Deepthi,S. Ramkanth,S. Angalaparameswari
International Journal of Research in Pharmaceutical Sciences , 2010,
Abstract: The drug product encompasses the pharmacologic activity with the pharmaceutical properties. The ideal characte-ristics are physical and chemical stability, ease of processing, accurate and reproducible delivery to the target or-gans and availability at the site of action. A Dry powder inhaler (DPI) is a device that delivers medication to the lungs in the form of a dry powder. For the DPI, these goals can be met with a suitable powder formulation, an efficient metering system and a perfectly selected device. This review focuses on the dry powder inhaler formulation, evaluation, material methods and development processes. Most of the dry powder inhaler formulation en-compasses micronized drug particles blended with larger carrier particles that promote the flow properties, re-duce aggregation and help in dispersion. A combination of the physicochemical properties, particle size, shape, surface area and morphology affects the forces of interaction and aerodynamic properties, which in turn deter-mine the fluidization, dispersion, delivery to the lungs and deposition in the peripheral airways. However the properties of free micronized powders often interfere with the drug handling and with drug delivery, reducing the dose consistency. Dry powder inhalers are evaluated by the drug product characterization studies such as the in vitro dose proportionality, effect of patient dose, priming etc. The development of the new designs of the DPI is governed by the driving forces such as the regulatory and pharmacopoeial requirements, delivery systems for the NCE, clinical factors and commercial factors.
Spatio-Temporally Adaptive Waiting Time for Cell Phone Sensor Networks
Deepthi Chander,Bhushan Jagyasi,U. B. Desai,S. N. Merchant
International Journal of Distributed Sensor Networks , 2011, DOI: 10.1155/2011/962476
Abstract: In cell phone sensor networks (CpSN), sensor-embedded cell phones communicate sensor data using Near Field Communication outlets such as Wi-Fi or Bluetooth. This paper considers a query dissemination application of CpSN, where sensor data belonging to a certain time window [ , ] is needed from a region of interest. Existing approaches, such as ADAPT, use adaptive broadcast ranges at the Wireless Access Point (WAP) for query dissemination. This paper proposes the adaptation of waiting time at nodes for energy-efficient query dissemination. The design and analysis of the proposed Spatio-Temporally Adaptive Distributed Velocity Dependent (STA-DVD) waiting time is presented. The STA-DVD protocol is analytically compared with a Spatially Adaptive Distributed Velocity Dependent (SA-DVD) waiting time based protocol. Simulation results show that STA-DVD has a superior querying performance in terms of number of samples procured than SA-DVD, at a slightly higher energy cost. For the case of a Randomized Waiting (RW) time adopted by nodes in ADAPT, the ADAPT-RW protocol has the best querying performance, with significantly high energy costs. STA-DVD has a comparable querying performance with ADAPT-RW, for high residual times and a better performance for low residual times, with significantly low energy dissipation. 1. Introduction Cell phone-based sensor networks are constituted by cell phones which are additionally empowered with sensing capabilities [1–6]. While the ubiquitous use of cell phones for regular voice applications resolves issues related to the deployment and provision of energy for the embedded sensors, the mobility of cell phone users provides improved coverage and energy efficiency [7, 8]. These networks can either use the cellular bandwidth (as in [9, 10]) or can use short-range communication outlets such as Wi-Fi or Bluetooth [11] to share sensor data. Cell phone-based sensor networks can cater to various urban sensing applications such as environmental monitoring, urban planning, natural resource management, civic hazard detection, and information sharing. Some of the on-going research in this relatively nascent area are discussed in Section 9. In this paper, we consider an architecture of cell phone-based sensor networks, where cell phones use short-range communications to transmit sensor data. Such networks (shown in Figure 1) are referred to as cell phone sensor networks (CpSNs). This paper specifically focusses on an application of CpSN which requires carbon monoxide (CO) levels, belonging to a particular time window , from a region of
Ethmoidal osteoid osteoma with orbital and intracranial extension – a case report
S Balaji Pai, K Harish, MS Venkatesh, Udayshankar, Deepthi Jermely
BMC Ear, Nose and Throat Disorders , 2005, DOI: 10.1186/1472-6815-5-2
Abstract: The authors report a case of a large osteoid osteoma of the ethmoid with intraorbital and intracranial extension in a 33 year old male patient. He presented with loss of vision in the left eye. The intra-cranial extension was excised through a single burr-hole fronto-orbitotomy. The ethmoid and orbital portions were approached and excised through a Weber-Ferguson incision and inferior orbitotomy. Radical excision of the tumor could thus be achieved through a craniofacial approach.Although benign and rare, skull base osteoid osteoma can present with neurological deficit due to its mass effect and involvement of vital structures. A multispeciality team approach is advisable in such cases if radical excision is to be achieved. A craniofacial approach made radical single stage excision of this multicompartmental osteoid osteoma possible with an uneventful postoperative period.Osteoid osteoma is a rare benign osteoblastic lesion usually involving the long bones of the lower limbs. Cranial involvement has been mainly localised to the skull vault. Osteoid osteoma of the skull base is a rare entity [1]. Surgical management of skull base osteoid osteoma may be challenging due to its proximity to vital structures, access and hard consistency. This report deals with a case of an ethmoidal osteoid osteoma invading the adjacent orbit and anterior cranial fossa and the team approach employed to achieve radical excision. The radiological findings and the surgical procedure employed are presented.A 33 year old male presented with decreased vision in the left eye and left sided headache of 3 months duration. Examination revealed left eye blindness with primary optic atrophy and no other neurological deficit. Imaging revealed a bony tumor in the left ethmoid sinus invading the left orbit and compressing the left optic nerve. Intracranial extension into the anterior cranial fossa on the left side was noted (Figure 1). Core biopsy of the mass showed an osteoid osteoma.A multispeciality
Image Compression Technique using Two Dimensional Discrete Cosine Transform
S. Rajeswari,,P.Deepthi,,K.V. Ramana Rao
International Journal of Innovative Technology and Exploring Engineering , 2012,
Abstract: This paper presents an architecture for the fast computation of the 8×8 two dimensional (2D) Inverse Discrete Cosine Transform. The proposed method is the permanent storage of the Basis Matrices of the 8×8 2D Discrete Cosine Transform (DCT). The sparseness property of the 2D DCT coefficient matrix, the computational time decreases as the number of nonzero coefficients decreases. The proposed structure computes all 64 pixel luminance values of an 8×8 block simultaneously. The design was implemented in Xilinx Xc3s500 board and the design used 23% LUT’s and 33% of the total slices. The total power consumed by the device was 0.081W.
Angiosomes of medial cord of brachial plexus
D. Suseelamma,S. Deepthi,K. Krishna Chaitanya,H. R. Sharada
International Journal of Research in Medical Sciences , 2013, DOI: 10.5455/2320-6012.ijrms20130508
Abstract: This anatomical study analyzed the neurovascular relationship of the brachial plexus. Ten formalized specimens of brachial plexuses were examined after injection of lead oxide in to the subclavian artery. The vascular, anatomical features of the brachial plexus were documented .The specimens were analyzed by dissection method, subjected for microscopic study. The vascular supply was markedly rich, often with true anastomotic channels found within the nerves. There was much variation in supply, depending on the branching pattern of subclavian artery. [Int J Res Med Sci 2013; 1(2.000): 79-82]
Radix formation between median and musculocutaneous nerves: embryological, morphological and clinical correlation
Suseelamma D,Krishna Chaitanya K,Sharada HR,Deepthi S
International Journal of Research in Medical Sciences , 2013, DOI: 10.5455/2320-6012.ijrms20130803
Abstract: In ours study we report radix formation between median nerve and musculocutaneous nerves. The study was conducted in the Department of Anatomy, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda Dt., Andhra Pradesh, India. During routine cadaveric dissections in the upper limbs, we observed an anastomosis (radix) between median and musculocutaneous nerves in the arm. Variations in the origin, course, branching pattern, communications was observed. These variations have clinical significance in brachial plexus block and surgical procedures. [Int J Res Med Sci 2013; 1(3.000): 222-225]
Distributed Velocity-Dependent Protocol for Multihop Cellular Sensor Networks
Deepthi Chander,Bhushan Jagyasi,U. B. Desai,S. N. Merchant
EURASIP Journal on Wireless Communications and Networking , 2009, DOI: 10.1155/2009/192985
Abstract: Cell phones are embedded with sensors form a Cellular Sensor Network which can be used to localize a moving event. The inherent mobility of the application and of the cell phone users warrants distributed structure-free data aggregation and on-the-fly routing. We propose a Distributed Velocity-Dependent (DVD) protocol to localize a moving event using a Multihop Cellular Sensor Network (MCSN). DVD is based on a novel form of connectivity determined by the waiting time of nodes for a Random Waypoint (RWP) distribution of cell phone users. This paper analyzes the time-stationary and spatial distribution of the proposed waiting time to explain the superior event localization and delay performances of DVD over the existing Randomized Waiting (RW) protocol. A sensitivity analysis is also performed to compare the performance of DVD with RW and the existing Centralized approach.
Effect of microwave drying in improving granule characteristics in tablets
Deepthi Shyju
Hygeia : Journal for Drugs and Medicines , 2010,
Abstract: In this study, Paracetamol was used as the model drug and the granules were prepared by microwave technique and fluid bed drying technique. The granules prepared by microwave technique and fluid bed drying technique were evaluated for parameters such as amount of fines, drying time, bulk density,compressibility,angle of repose etc.The data indicated that the granules retained their structure in comparison with the conventional drying process. The prepared granules were compressed into tablets and evaluated for hardness, friability, disintegration, and dissolution etc.
In-Situ Domestic Load Harmonic Detection and Reduction Based on GLRM Algorithm for Optimum Filter Excerpt  [PDF]
Deepthi Joseph, N. Kalaiarasi, K. Rajan
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.79182
Abstract: Power Quality measures the reliable operation between the system and to the connected loads of same system. A poor power quality causes physical damage to the equipment and also results in lower productivity with increase in energy costs. Power disturbances range from micro seconds to hours and the prolonged disturbances in hours would damage the equipments. The power quality decreases due to growth of nonlinear loads in domestic appliances, such as home Uninterrupted Power Supplies (UPS), Induction stove, Television etc. Nowadays Domestic loads are controlled or powered with power electronic devices. The power electronic devices with Direct Current (DC) components generate high frequency signal for DC-Alternating Current (AC) conversion. The conversion introduces multiple frequencies in the AC power supply. The multiple frequencies in AC power supply are called as harmonics. The harmonics in AC supply affects the lifetime of home appliances, consumes more electric current, affects the power factor, transformer efficiency, and other electricity supply systems. Till now, to avoid harmonics, the filters are erected only in industrial loads or in the substations. In this paper a novel method to detect and control harmonics in domestic appliances is proposed. Harmonic control with various filters in the filter bank, based on detection of harmonic voltage let out from the domestic appliances for power saving. To select the appropriate filter to improve power quality, we apply a novel Genetic Algorithm based Linear Regression Method (GLRM) algorithm for optimum Filter Selection. From the results we were able to reduce the total harmonic distortion level to 3.68%.The current consumption of each household appliance is reduced considerably and finally the electricity bill is reduced to 15% and overall system efficiency improves to 85%.
An Unusual Occurrence of Colisepticemia in Budgerigars (Melopsittacus undulatus)
P.M. Priya,Deepthi S. Pillai,P. Rameshkumar,P. Senthamilselvan
International Journal of Poultry Science , 2008,
Abstract: A rare case of colisepticemia in budgerigar was reported from Kerala. Overcrowding coincident with increased noise and low light levels appeared to be the predisposing factors.
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