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Search Results: 1 - 10 of 200762 matches for " Deepali P. Sundrani "
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Matrix Metalloproteinase-1 and -9 in Human Placenta during Spontaneous Vaginal Delivery and Caesarean Sectioning in Preterm Pregnancy
Deepali P. Sundrani, Preeti M. Chavan-Gautam, Hemlata R. Pisal, Savita S. Mehendale, Sadhana R. Joshi
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0029855
Abstract: Preterm birth is a major public health problem in terms of loss of life, long-term and short term disabilities worldwide. The process of parturition (both term and preterm) involves intensive remodelling of the extracellular matrix (ECM) in the placenta and fetal membranes by matrix metalloproteinases (MMPs). Our previous studies show reduced docosahexaenoic acid (DHA) in women delivering preterm. Further omega 3 fatty acids are reported to regulate MMP levels. This study was undertaken to examine the placental levels of MMPs and their association with placental DHA levels in women delivering preterm. The levels of MMP-1 and MMP-9 in 74 women delivering preterm (52 by spontaneous vaginal delivery and 22 by caesarean sectioning) and 75 women delivering at term (59 by spontaneous vaginal delivery and 16 by caesarean sectioning) were determined by enzyme-linked immunosorbent assay (ELISA) and their association with placental DHA was studied. Placental MMP-1 levels were higher (p<0.05) in women delivering preterm (both by spontaneous vaginal delivery and caesarean sectioning) as compared to those delivering at term. In contrast, placental MMP-9 levels in preterm pregnancies was higher (p<0.05) in women with spontaneous vaginal delivery while lower (p<0.05) in women delivering by caesarean sectioning. Low placental DHA was associated with higher placental MMP-9 levels. Our study suggests a differential effect of mode of delivery on the levels of MMPs from placenta. Further this study suggests a negative association of DHA and the levels of MMP-9 in human placenta although the mechanisms need further study.
Role of Immunoglobulins for the Prevention of Serious Infections in Adults with Human Immunodeficiency Virus Infection
K. C. Mohanty, R. M. Sundrani, A. P. Lale
JK Science : Journal of Medical Education & Research , 1999,
Abstract: Present stud) "as conducted on eighteen HIV infected adult patients to assess the efficacy ofIntralenous unmunoglobulins (IVlG) therapy in preventing infections in a prospective randomizedout-pallent clinical trial. Intravenous immunoglobulin therapy was instituted for a period of one year Results of the therapy showed remarkable reduction in frequency of serious infections, bellerquality of life by reducing number of days with fever and frequency of diarrhoea, frequency andduration of hospitalization also markedly reduced.
Bioremediation of Chromium (VI) from Textile Industry’s Effluent and Contaminated Soil Using Pseudomonas putida
Deepali
Iranica Journal of Energy and Environment (IJEE) , 2011,
Abstract: Nine bacterial colonies were screened for the Cr(VI) removal efficiency and out of these three bacterial strains Pseudomonas putida, Pseudomonas aeruginosa and Bacillus sp. were isolated from soil and used to remove Cr(VI) from aqueous solution. The effect of time and concentrations on the removal rate of hexavalent chromium were studied using batch experiment. Maximum Cr (VI) removal was noted 75.0% by Bacillus sp. at 10mg/l, 69.70% by Pseudomonas aeruginosa at 40mg/l and 90.88% by Pseudomonas putida at 10mg/l of synthetic solution, during 96 hours. Among these three bacteria, the maximum Cr(VI) removal was reported by Pseudomonas putida on lower concentration. On the basis of highest removal rate, Pseudomonas putida was selected and used for further chromium removal from samples. It was found to be removed the highest Cr(VI) by 82.92%, from effluent and 74.41% from soil during 96 hours. The present study depicts that bacteria removes chromium efficiently and this could be used for industrial waste management and other environmental contaminants.
Exploring Methods of Replacement of Concrete Road in Two Days
Deepak Sundrani,Yusuf Inamdar
International Journal of Engineering and Advanced Technology , 2012,
Abstract: In India, repairing / replacing of concrete road takesweeks, sometimes months and sometimes years. At many placesBitumen roads are preferred because they can be repaired veryfast. However in some South East Asian Asian countries, cityroads made of concrete, are replaced in two days. In a four laneroad, two lanes are dug up on Saturday, the rubble is transportedaway and fresh ready mixed concrete is poured on Sunday and onMonday the traffic commences as usual on the new concrete road.Thus on the two days when traffic is thin because of offices havingholidays is utilized to replace the concrete road. On next Saturdayand Sunday, the process is repeated for the balance part of theconcrete road. Time saving is the biggest benefit. The troublecaused to innumerable city persons travelling can be drasticallycut. If we can calculate the benefit of this, then the benefit costratio will be much more than one.The paper attempts to explorethe various possible methods of replacing a concrete road in twodays.
Chromium Uptake Efficiency of Spinacea olaracea from Contaminated Soil
GKK Deepali
Journal of Applied Sciences and Environmental Management , 2009,
Abstract: The aim of the study was to evaluate the uptake of chromium by Spinacea olaracea and its accumulation in roots and shoots of plants grown in pots at various concentrations of chromium (30, 60, 90,120,150 mg/l). The results revealed that the levels of chromium accumulation in roots and shoots were higher at minimum concentration level
Allan Sealy's The Everest Hotel: A Calender – An Ecocritical Analysis
Deepali Yadav
Golden Research Thoughts , 2012, DOI: 10.9780/22315063
Abstract: Ecocriticism refers to the interdisciplinary study of literature and environment. The study has developed in last few decades, observing the effects of climatic changes and increased rate of global warming. The present paper explores the literary theory of Ecocriticism which emphasizes on fictional (and artistic) manifestation of human experiences inherent in sorrows of scarcity, hopes for harmonious existence, fears of loss and disaster. It is an ecocentric valuation of the place near Indian Himalayas trying to depict the industrialization and its ill effects on the snow-capped hills, through Indian novel “The Everest Hotel: ACalender”, by I. Allan Sealy
Analyzing Issues in Mobile Wimax Handover Using Qualnet Simulator
Deepali Gawali
International Journal of Basics and Applied Science , 2012,
Abstract: Wireless networks are very common for both organizations and individuals. Wireless networking prone to some security issues.so its very important to define effective wireless security policies that gurad against unauthorized access to important resources. In the existing research there is lack of integrated presentation of solution to all the security issues of Wimax network. This paper discusses the security issues in Wimax and comparative analysis between network without security and with security.
RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF VALSARTAN AND HYDROCHLOROTHIAZIDE IN SOLID DOSAGE FORM
Sheikh Rahila J,Puranik Manisha P,Bavadkar Deepali N,Mali Prabha R
International Research Journal of Pharmacy , 2011,
Abstract: A simple, selective, rapid, precise and economical reverse phase HPLC method has been developed for the simultaneous estimation of Valsartan and Hydrochlorothiazide in solid dosage form. The method was carried out on a C18 Intersil (250 X 4.6 i.d., particle size 10μm) column with a mobile phase consisting of 0.02M Potassium dihydrogen orthophosphate:Methanol:Triethylamine [25:75:0.2 %v/v/v, pH 6.0]at a flow rate of 1.0 mL/min. Detection was carried out at 259 nm. The retention time of Valsartan and Hydrochlorothiazide was found to be 4.15 and 3.20 min, respectively. The developed method was validated in terms of accuracy, precision, linearity, limit of detection and limit of quantitation and can be used for the estimation of these drugs in combined pharmaceutical dosage forms.
RsaI repetitive DNA in Buffalo Bubalus bubalis representing retrotransposons, conserved in bovids, are part of the functional genes
Deepali Pathak, Sher Ali
BMC Genomics , 2011, DOI: 10.1186/1471-2164-12-338
Abstract: We cloned and sequenced RsaI repeat fragments pDp1, pDp2, pDp3, pDp4 of 1331, 651, 603 and 339 base pairs, respectively from the buffalo, Bubalus bubalis. Upon characterization, these fragments were found to represent retrotransposons and part of some functional genes. The resultant clones showed cross hybridization only with buffalo, cattle, goat and sheep genomic DNA. Real Time PCR, detected ~2 × 104 copies of pDp1, ~ 3000 copies of pDp2 and pDp3 and ~ 1000 of pDp4 in buffalo, cattle, goat and sheep genomes, respectively. RsaI repeats are transcriptionally active in somatic tissues and spermatozoa. Accordingly, pDp1 showed maximum expression in lung, pDp2 and pDp3 both in Kidney, and pDp4 in ovary. Fluorescence in situ hybridization showed repeats to be distributed all across the chromosomes.The data suggest that RsaI repeats have been incorporated into the exonic regions of various transcribing genes, possibly contributing towards the architecture and evolution of the buffalo and related genomes. Prospects of our present work in the context of comparative and functional genomics are highlighted.Different families of repetitive DNA contribute towards architectural organization of the mammalian genomes [1]. They represent both, tandemly arranged and interspersed sequences [2]. Based on their size and mode of propagation, Interspersed elements can be divided into two separate classes, the long terminal repeat (LTR) and non-LTR. The non LTR LINEs (long interspersed repeat elements) and SINEs (Short interspersed repeat elements) are widely distributed occupying a substantial fraction of the eukaryotic genomes. These elements replicate and proliferate themselves through a "copy and paste" mechanism called retrotransposition [3,4]. In this process, transcription of their genomic copies is followed by an RNA intermediate resulting cDNAs reintegration at a new location in the genome [5]. Approximately, 100 LINE and SINE families have been reported to date in various eukar
An assessment of the efficacy and safety of cross technique with 100% TCA in the management of ice pick acne scars
Bhardwaj Deepali,Khunger Niti
Journal of Cutaneous and Aesthetic Surgery , 2010,
Abstract: Background : Chemical reconstruction of skin scars (CROSS) is a technique using high concentrations of trichloroacetic acid (TCA) focally on atrophic acne scars to induce inflammation followed by collagenisation. This can lead to reduction in the appearance of scars and cosmetic improvement. Aims : The aim of this pilot study is to investigate the safety of the CROSS technique, using 100% TCA, for atrophic ice pick acne scars. Settings and Design : Open prospective study. Materials and Methods : Twelve patients with predominant atrophic ice pick post acne scars were treated with the CROSS technique, using 100% TCA, applied with a wooden toothpick, at two weekly intervals for four sittings. Efficacy was assessed on the basis of the physician′s clinical assessment, photographic evaluation at each sitting and patient′s feedback after the fourth treatment, and at the three-month and six-month follow-up period, after the last treatment. Results : More than 70% improvement was seen in eight out of ten patients evaluated and good results (50 - 70% improvement) were observed in the remaining two patients. No significant side effects were noted. Transient hypopigmentation and hyperpigmentation was observed in one patient each. Physician′s findings were in conformity with the patient′s assessment. Three months after the last treatment, one patient noted a decrease in improvement with no further improvement even at the six-month follow-up period. Conclusion : The CROSS technique with 100% TCA is a safe, efficacious, cost-effective and minimally invasive technique for the management of ice pick acne scars that are otherwise generally difficult to treat. In few patients the improvement may not be sustained, probably due to inadequate or delayed collagenisation.
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