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Search Results: 1 - 10 of 9181 matches for " Deepak Sharma "
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Analysis of Activation Energies & Experimental Evidence for Energetic Phase Separation in GexSe1-xGlassy System  [PDF]
Deepak Sharma, Anand Mohan Awasthi
New Journal of Glass and Ceramics (NJGC) , 2014, DOI: 10.4236/njgc.2014.42005
Abstract: Glass science reveals peculiar properties due to the lack of long range order and presence of heterogeneity in Chalcogenide glasses. In thermal studies, structural relaxation at the glass transition region is governed by the activation energy of the cooperative unit (zU). In the cooperative molecular dynamics, we are considering the analysis of three activation energies, namely activation energy per BMS (U), activation energy of the cooperative unit (zU) and the apparent activation energy (z2U). From the energetic dynamics of activation energy analysis across the GexSe1-x glass series, data represent three-phase segregation. From our data, we also observed that the value of UCRR/RTg across the GexSe1-x glass series is nominally changed from 34.343 to 36.19.
Inception of E-Governance Initiatives in India: A Journey towards Good Governance
Deepak Sharma
International Journal of Computer Science and Management Studies , 2012,
Abstract: India is passing through a stage, where huge changes are taking place both in the business sector as well as in government sector. New prospects of growth and prosperity are opening up and tremendous opportunities are unfolding from which business world as well as governments can benefit. The role of knowledge is crucial in coping up with the rising demands and expectations of the people. Governanceissues are multifaceted and simple to get incorrect, but EGovernmentsuccess depends on getting them right. E governance is one of the important tools which brought a revolution in leadership, organizational structure, quality of services, transparency and accountability process of governance. Constitution of National knowledge commission is one the serious step in transforming India into global knowledge nucleus. The study throws light on initiatives of E Government and assesses its impact on society across the country. The paper points out various gaps hindering implementation of E-Governance and provides a range of remedies to overcome problems faced in process of EGovernment.
Anesthetic Management of Nasal Glomus Angioma - A Rare Vascular Tumour
Deepak Sharma
JK Science : Journal of Medical Education & Research , 2007,
Abstract: Not available
Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate for Respiratory Disorders
Deepak Sharma
ISRN Pharmaceutics , 2013, DOI: 10.1155/2013/674507
Abstract: Recent developments in fast disintegrating tablets have brought convenience in dosing to pediatric and elderly patients who have trouble in swallowing tablets. The objective of the present study was to prepare the fast disintegrating tablet of salbutamol sulphate for respiratory disorders for pediatrics. As precision of dosing and patient's compliance become important prerequisites for a long-term treatment, there is a need to develop a formulation for this drug which overcomes problems such as difficulty in swallowing, inconvenience in administration while travelling, and patient’s acceptability. Hence, the present investigation were undertaken with a view to develop a fast disintegrating tablet of salbutamol sulphate which offers a new range of products having desired characteristics and intended benefits. Superdisintegrants such as sodium starch glycolate was optimized. Different binders were optimized along with optimized superdisintegrant concentration. The tablets were prepared by direct compression technique. The tablets were evaluated for hardness, friability, weight variation, wetting time, disintegration time, and uniformity of content. Optimized formulation was evaluated by in vitro dissolution test, drug-excipient compatibility, and accelerated stability study. It was concluded that fast disintegrating tablets of salbutamol sulphate were formulated successfully with desired characteristics which disintegrated rapidly; provided rapid onset of action; and enhanced the patient convenience and compliance. 1. Introduction Despite tremendous innovations in drug delivery, the oral route remains the preferred route for administration of therapeutic agents because of accurate dosage, low cost therapy, self medication, noninvasive method, and ease of administration leading to high level of patient compliance [1]. The most popular dosage forms are conventional tablets and hard gelatin capsules. One important drawback of such dosage forms is “dysphagia” or difficulty in swallowing for many patients; almost 50% of the population is affected by such problem. Hence, patients do not comply with prescription, which results in high incidence of noncompliance and ineffective therapy [2].Recently, fast disintegrating drug delivery systems have started gaining popularity and acceptance as new drug delivery systems, because they are easy to administer and lead to better patient compliance [3]. In some cases such as motion sickness, sudden episodes of allergic attacks or coughing, and unavailability of water, swallowing conventional tablets may be difficult.
Evolutionary Constraints Acting on DDX3X Protein Potentially Interferes with Rev-Mediated Nuclear Export of HIV-1 RNA
Deepak Sharma,Jayanta Bhattacharya
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0009613
Abstract: Differential host-pathogen interactions direct viral replication in infected cells. In HIV-1 infected cells, nuclear export of viral RNA transcripts into cellular cytoplasm is governed by interaction of HIV-1 Rev, Exportin-1 (CRM-1) and DDX3X. Knock down of DDX3X has been shown to drastically impair HIV replication. Here we show that evolutionary forces are responsible for demarking previously unidentified critical functionally important residues on the surface of DDX3X. Using computational approaches, we show that these functional residues, depending on their location, are capable of regulating ATPase and RNA helicase functions of DDX3X. The potential of these residues in designing better blockers against HIV-1 replication was also assessed. Also, using stepwise docking simulations, we could identify DDX3X-CRM-1 interface and its critical functional residues. Our data would help explain the role of DDX3X in HIV-1 Rev function with potential to design new intervention strategies against HIV-1 replication.
Minimizing Rental Cost under Specified Rental Policy in Two Stage Open shop Scheduling Problem
Deepak Gupta,Pooja Sharma
International Journal of Engineering Sciences & Research Technology , 2013,
Abstract: This Paper is an attempt to study two stage open shop scheduling problem in which processing time of the jobs are given. The objective of the paper is to obtain an algorithm to minimize the rental cost of the machines in two stage open shop scheduling problem under specified rental policy. A numerical illustration is given to justify the proposed algorithm.
Results of Comparative Analysis of BPSK & QPSK using Equalized OFDM.
Meenakshi Chourasiya,Deepak Sharma
International Journal of Engineering Sciences & Research Technology , 2012,
A Computed Tomographic Study of Canal Variations in Maxillary & Mandibular first Premolar Teeth in Jaipur Population – An in vitro Study.
Deepak Sharma,,Meetu Mathur
People's Journal of Scientific Research , 2011,
Abstract: The present study was carried out to observe root canal variations in maxillary and mandibular first premolarteeth in the local population using spiral computed tomography. Sixty, each of well formed maxillary and mandibular firstpremolar teeth without any carious lesions were used in this study. They were placed in 5% sodium hypochlorite solutionfor 30 minutes for the removal of organic debris. They were then stored in normal saline till further experiment was carriedout. Each tooth was scanned with a slice thickness of 0.625 mm. Data collected was used to reconstruct the scanned teeththree dimensionally. The configuration seen in longitudinal and transverse sections was used to classify the canal anatomyaccording to Vertucci’s classification.
Anaesthetic Management of Myasthenia Gravis with Thymic Mass in Facial Trauma
Deepak Sharma,Dheer Singh
Indian Anaesthetists' Forum , 2010,
Abstract: Myasthenia gravis is an immunologic disorder characterised by polyclonal antibodies directed against nicotinic acetylcholine receptors at postneuromuscular junction. This case describes perioperative management of a patient suffering facial trauma with underlying myasthenia gravis with thymic mass
Malpositioned Right Subclavian Vein Catheter into Contralateral Subclavian Vein-A Case Report
Deepak Sharma,Ritu Goyal
Indian Anaesthetists' Forum , 2009,
Abstract: Malposition of central venous catheter is well known technical complication. A case with unusual placement of right subclavian vein catheter into contralateral subclavian vein, when inserted through infraclavicular approach, is reported.
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