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匹配条件: “Deb Binayak” ,找到相关结果约521条。
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Failure in Developing Effective Treatment for Cerebral Ischemia: The Stair Recommendations
Deb Binayak,Ramani Divya K
International Journal of Research in Pharmacy and Science , 2011,
Abstract: Cerebral ischemia leads to neurological dysfunction and activate complex signalling cascades, which may depreciate survival mechanisms as a result of cellular homeostatic breakdown. For acute ischaemic stroke, safe and effective treatments that offer an extended therapeutic window are urgently needed to decrease disability and aid neurological recovery. The benefit of recombinant tissue-type plasminogen activator (rt-PA) when initiated within 3 hours of stroke onset documents that acute ischemic stroke can indeed respond to treatment. This news is countered by the current lack of documentation that any purported neuroprotective drug significantly improves outcome when given after stroke onset. Lessons have been learned from the innumerable unsuccessful thrombolytic and neuroprotective trials, suggesting that future, better designed trials will likely demonstrate significant benefits with appropriate safe and effective drug treatments initiated within 6 hours of stroke onset. Also, the age of combination drug trials is approaching and combination treatments directed at both the vascular and cellular mechanisms of ischemic brain injury are likely to have the greatest impact upon stroke disability. The apparent failure of neuroprotection for acute ischemic stroke has caused a series of active discussions in both academic and industrial fields, which is fruitful and constructive in attempts to establish criteria for preclinical stroke studies. Since the Stroke Therapy Academic Industry Roundtable (STAIR) published its first criteria in 1999 and updated, quality of study design problems and inflation of reported efficacy of neuroprotectants have continued to be major issues in this field. Translational research of neuroprotection for ischemic stroke has reached its critical stage. A strategic reconsideration is urgently needed to aid in the search for new solutions
DEMOGRAPHIC AND CLINICAL ASPECTS OF TUBERCULOSIS: A CASE SERIES OF PATIENTS FROM IN-PATIENT DEPARTMENT OF A HOSPITAL
Deb Binayak,Goud Pruthviswar C,Rushendran R,Poojitha M
International Research Journal of Pharmacy , 2013, DOI: 10.7897/2230-8407.04353
Abstract: Controlling tuberculosis in India is a tremendous challenge. The disease is a major barrier to social and economic development. Based on the current scenario, the present observational prospective study was designed for 63 patients with tuberculosis admitted in in-patient department of a government general hospital in four months. Case sheets and laboratory reports of patients were collected and noted for evaluation. The study included patients who were all having active disease and absence of HIV infection. The follow-up of the patients was done every day. The case sheets of the patients revealed their age distribution, gender, body weight distribution, history of illness and previous illness, social habits, common and uncommon signs and symptoms, diagnostic tests performed, treatment therapy provided and adverse effects. Early identification of TB cases and the effective use of the first line drugs were the primary goals of the department. The common clinical features observed in the patients as well as the therapy provided by the physicians was typical and as per the Revised National Tuberculosis Control Programme of Government of India. Non-adherence, drug resistance, extra-pulmonary disease and severe contaminant disease states were not observed.
Assessment of the Prescribing Pattern of Antibiotics with Corticosteroids in Infective Acute Exacerbation of Chronic Bronchitis - A Case Series
Soti Varun K,Sarangi B,Deb Binayak,Alekya K
International Journal of Research in Pharmacy and Science , 2012,
Abstract: Chronic bronchitis has significant impact on morbidity.. The present study was conducted to assess the prescribing pattern of antibiotics along with systemic corticosteroids and the rationality of treatment in AECB patients. A six months retrospective study was conducted by assessing eighty one cases admitted to medical wards at a government secondary care hospital in Nilgiris, Tamil nadu. The average age of patients reported 50.58 years treated for duration of 11.58 days. 88.89% were smokers, 82.71% alcoholic and 59.25% tobacco/pan masala chewers. The most prescribed antibiotic was Cefotaxime. Others include- Cefixime, Ceftriaxone, Cephalexin, Amoxicillin, Ampicillin, Garamycin and Azithromycin. Most frequently prescribed systemic corticosteroids were Dexamethasone and Prednisolone. An average of 2.19 antibiotics was prescribed for AECB management. Increase in duration of treatment for individual patient was due to non-specific prescription. The prescribing of corticosteroids along with antibiotics could not reduce treatment duration because microbial inflammation was not controlled with antibiotics prescribed for them. It concluded that prescribing pattern of drugs is irrational. The increasing levels of antibacterial resistance among common respiratory tract pathogens implicated in AECB may threaten use of many currently recommended treatment options and has highlighted the need for alternative antibacterial agents.
Complex Optical Potentials and Pseudo-Hermitian Hamiltonians
Ram Narayan Deb,Avinash Khare,Binayak Dutta Roy
Physics , 2002, DOI: 10.1016/S0375-9601(02)01725-5
Abstract: Recently some authors have broadened the scope of canonical quantum mechanics by replacing the conventional Hermiticity condition on the Hamiltonian by a weaker requirement through the introduction of the notion of pseudo-Hermiticity. In the present study we investigate eigenvalues, transmission and reflection from complex optical potentials enjoying the property of pseudo-Hermiticity.
A common unique fixed point theorem for two random operators in Hilbert spaces
Binayak S. Choudhury
International Journal of Mathematics and Mathematical Sciences , 2002, DOI: 10.1155/s0161171202005616
Abstract: We construct a sequence of measurable functions and consider its convergence to the unique common random fixed point of two random operators defined on a nonempty closed subset of a separable Hilbert space. The corresponding result in the nonrandom case is also obtained.
An iteration for finding a common random fixed point
Binayak S. Choudhury
International Journal of Stochastic Analysis , 2004, DOI: 10.1155/s1048953304208012
Abstract: We define a random iteration scheme and consider its convergence to a common random fixed point of two random operators defined on a convex subset of a separable Hilbert space. We also consider the case when the subset is further compact.
Convergence of a random iteration scheme to a random fixed point
Binayak S. Choudhury
International Journal of Stochastic Analysis , 1995, DOI: 10.1155/s104895339500013x
Abstract: This paper discusses the convergence of random Ishikawa iteration scheme to a random fixed point for a certain class of random operators.
Unique Fixed Point Theorem for Weakly C-Contractive Mappings
Binayak S Choudhury
Kathmandu University Journal of Science, Engineering and Technology , 2009, DOI: 10.3126/kuset.v5i1.2842
Abstract: In this work we introduce the class of weakly c-contractive mappings. We establish that these mappings necessarily have unique fixed points in complete metric spaces. We support our result by an example. Our result also generalises an existing result in metric spaces. Key words : Metric space; Fixed point; Weak C-contraction. M S C (2000): 54H25 ? DOI: 10.3126/kuset.v5i1.2842 Kathmandu University Journal of Science, Engineering and Technology Vol.5, No.1, January 2009, pp 6-13
Domestic Violence: A Social Issue in Rural Tripura  [PDF]
Jayanta Choudhury, Moutoshi Deb
Advances in Applied Sociology (AASoci) , 2015, DOI: 10.4236/aasoci.2015.510024
Abstract: Domestic violence is a wide spread problem, its actual extent is difficult to measure. According to available statistics throughout the world, about 33 percent women have experienced violence at some point of their life (WHO, 1997). In India, women form about half of the population and enjoy various freedom and rights but simultaneously, like other developing countries, violence against women is overwhelming and is a matter of concern. Domestic violence leads to violence of human rights and prevents them from enjoying their fundamental rights. Though the types of violence differs from society to society, nations to nations, religion to religion, but it prevails in underdeveloped, developing and developed countries, too. Domestic violence refers to “assaultive and coercive behaviours that adults use against their intimate partners” (Holden, 2003). In India, there are a set of well equipped legislations which protect women against violence. And Protection of Women against Domestic Violence Act, 2005 is the milestone in the history of legal control and judicial response in domestic violence affairs. But the rate of violence against women increased 44 percent during 1993 to 2011. The findings of the paper are expected to enlighten individuals and the community on the causes and consequences of violence against women. The paper comes out with policy prescription for government and non-government organizations towards addressing the problem.
Weak and strong convergence theorems of a multistep iteration to a common fixed point of a family of nonself asymptotically nonexpansive mappings in banach spaces
Banerjee,Shrabani; Choudhury,Binayak S;
Cubo (Temuco) , 2012, DOI: 10.4067/S0719-06462012000300010
Abstract: in this paper we have defined a multistep iterative scheme with errors involving a family of asymptotically nonexpansive nonself mappings in banach spaces. a retraction has been used in the construction of theiteration. we prove here weak and strong convergences of the iteration to common fixed points of the family of asymptotically nonexpansive nonself mappings. we have used several concepts of banach space geometry. our results improve and extend some recent results.
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