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Search Results: 1 - 10 of 930149 matches for " De-Carvalho M.C.A. "
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Modulation of fibronectin expression in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis
De-Carvalho, M.C.A.;Chimelli, L.M.C.;Quirico-Santos, T.;
Brazilian Journal of Medical and Biological Research , 1999, DOI: 10.1590/S0100-879X1999000500012
Abstract: fibronectin (fn), a large family of plasma and extracellular matrix (ecm) glycoproteins, plays an important role in leukocyte migration. in normal central nervous system (cns), a fine and delicate mesh of fn is virtually restricted to the basal membrane of cerebral blood vessels and to the glial limitans externa. experimental autoimmune encephalomyelitis (eae), an inflammatory cns demyelinating disease, was induced in lewis rats with a spinal cord homogenate. during the preclinical phase and the onset of the disease, marked immunolabelling was observed on the endothelial luminal surface and basal lamina of spinal cord and brainstem microvasculature. in the paralytic phase, a discrete labelling was evident in blood vessels of spinal cord and brainstem associated or not with an inflammatory infiltrate. conversely, intense immunolabelling was present in cerebral and cerebellar blood vessels, which were still free from inflammatory cuffs. shortly after clinical recovery minimal labelling was observed in a few blood vessels. brainstem and spinal cord returned to normal, but numerous inflammatory foci and demyelination were still evident near the ventricle walls, in the cerebral cortex and in the cerebellum. intense expression of fn in brain vessels ascending from the spinal cord towards the encephalon preceded the appearance of inflammatory cells but faded away after the establishment of the inflammatory cuff. these results indicate an important role for fn in the pathogenesis of cns inflammatory demyelinating events occurring during eae.
Modulation of fibronectin expression in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis
De-Carvalho M.C.A.,Chimelli L.M.C.,Quirico-Santos T.
Brazilian Journal of Medical and Biological Research , 1999,
Abstract: Fibronectin (FN), a large family of plasma and extracellular matrix (ECM) glycoproteins, plays an important role in leukocyte migration. In normal central nervous system (CNS), a fine and delicate mesh of FN is virtually restricted to the basal membrane of cerebral blood vessels and to the glial limitans externa. Experimental autoimmune encephalomyelitis (EAE), an inflammatory CNS demyelinating disease, was induced in Lewis rats with a spinal cord homogenate. During the preclinical phase and the onset of the disease, marked immunolabelling was observed on the endothelial luminal surface and basal lamina of spinal cord and brainstem microvasculature. In the paralytic phase, a discrete labelling was evident in blood vessels of spinal cord and brainstem associated or not with an inflammatory infiltrate. Conversely, intense immunolabelling was present in cerebral and cerebellar blood vessels, which were still free from inflammatory cuffs. Shortly after clinical recovery minimal labelling was observed in a few blood vessels. Brainstem and spinal cord returned to normal, but numerous inflammatory foci and demyelination were still evident near the ventricle walls, in the cerebral cortex and in the cerebellum. Intense expression of FN in brain vessels ascending from the spinal cord towards the encephalon preceded the appearance of inflammatory cells but faded away after the establishment of the inflammatory cuff. These results indicate an important role for FN in the pathogenesis of CNS inflammatory demyelinating events occurring during EAE.
A bilevel decomposition technique for the optimal planning of offshore platforms
Carvalho, M.C.A.;Pinto, J.M.;
Brazilian Journal of Chemical Engineering , 2006, DOI: 10.1590/S0104-66322006000100008
Abstract: there is a great incentive for developing systematic approaches that effectively identify strategies for planning oilfield complexes. this paper proposes an milp that relies on a reformulation of the model developed by tsarbopoulou (ucl m.s. dissertation, london, 2000). moreover, a bilevel decomposition technique is applied to the milp. a master problem determines the assignment of platforms to wells and a planning subproblem calculates the timing for fixed assignments. furthermore, a heuristic search procedure that relies on the distance between platforms and wells is applied in order to reduce the search region. results show that the decomposition approach using heuristic generates optimal solutions for instances of up to 500 wells and 25 platforms in 10 discrete time periods that otherwise could not be solved with a full-scale approach. one important feature regarding these instances is that they correspond to problems of real-world dimension.
Cases of human envenoming caused by Philodryas olfersii and Philodryas patagoniensis (serpentes: Colubridae)
Araújo, Maria Elisabeth de;Santos, Ana Cristina M.C.A. dos;
Revista da Sociedade Brasileira de Medicina Tropical , 1997, DOI: 10.1590/S0037-86821997000600013
Abstract: the present paper reports two cases of human envenoming by colubrid snakes of philodryas, considered as not poisonous, showing evidence of the clinical aspects and the evolution of the symptoms of envenoming. the similarity of these cases with those caused by bothrops suggests a more careful evaluation on the victims considering the medical treatment to be adopted.
Cases of human envenoming caused by Philodryas olfersii and Philodryas patagoniensis (serpentes: Colubridae)
Araújo Maria Elisabeth de,Santos Ana Cristina M.C.A. dos
Revista da Sociedade Brasileira de Medicina Tropical , 1997,
Abstract: The present paper reports two cases of human envenoming by colubrid snakes of Philodryas, considered as not poisonous, showing evidence of the clinical aspects and the evolution of the symptoms of envenoming. The similarity of these cases with those caused by Bothrops suggests a more careful evaluation on the victims considering the medical treatment to be adopted.
Identification of Clostridium chauvoei in clinical samples cultures from blackleg cases by means of PCR
Miyashiro, S.;Nassar, A.F.C.;Souza, M.C.A.M.;Carvalho, J.B.;Adegas, J.E.B.;
Brazilian Journal of Microbiology , 2007, DOI: 10.1590/S1517-83822007000300020
Abstract: c. chauvoei presence was detected by means of polymerase chain reaction (pcr) from supernatant of culture in cooked meat medium of liver, muscle and metatarsian bone marrow samples of seven calves with blackleg symptoms. the isolation under anaerobic conditions of one muscle sample revealed clostridium perfringens in pure culture.
A numerical solution for the entrance region of non-newtonian flow in annuli
Maia, M.C.A.;Gasparetto, C.A.;
Brazilian Journal of Chemical Engineering , 2003, DOI: 10.1590/S0104-66322003000200014
Abstract: continuity and momentum equations applied to the entrance region of an axial, incompressible, isothermal, laminar and steady flow of a power-law fluid in a concentric annulus, were solved by a finite difference implicit method. the newtonian case was solved used for validation of the method and then compared to reported results. for the non-newtonian case a pseudoplastic power-law model was assumed and the equations were transformed to obtain a pseudo-newtonian system which enabled its solution using the same technique as that used for the newtonian case. comparison of the results for entrance length and pressure drop with those available in the literature showed a qualitative similarity, but significant quantitative differences. this can be attributed to the differences in entrance geometries and the definition of asymptotic entrance length.
A numerical solution for the entrance region of non-newtonian flow in annuli
Maia M.C.A.,Gasparetto C.A.
Brazilian Journal of Chemical Engineering , 2003,
Abstract: Continuity and momentum equations applied to the entrance region of an axial, incompressible, isothermal, laminar and steady flow of a power-law fluid in a concentric annulus, were solved by a finite difference implicit method. The Newtonian case was solved used for validation of the method and then compared to reported results. For the non-Newtonian case a pseudoplastic power-law model was assumed and the equations were transformed to obtain a pseudo-Newtonian system which enabled its solution using the same technique as that used for the Newtonian case. Comparison of the results for entrance length and pressure drop with those available in the literature showed a qualitative similarity, but significant quantitative differences. This can be attributed to the differences in entrance geometries and the definition of asymptotic entrance length.
Resistência e tolerancia a impacto transversal de baixa energia de um laminado híbrido metal/fibra
Gualberto, A.R.M.;Gatt, M.C.A.;Tarpani, J.R.;
Matéria (Rio de Janeiro) , 2009, DOI: 10.1590/S1517-70762009000200004
Abstract: the absorbed energy during the low-velocity transversal impact of hybrid metal/fiber glaretm laminate was determined by three different analytical methods. the first method employs a sophisticated laser-doppler apparatus that registers the acceleration and deceleration of the impact tup along the drop-weight test, whereas the second one is based only on the impact load-time history. the third method relies solely on the pre- and post-impact velocity of the striker. it has been concluded that the first two methodologies produce very similar results, with the material generally absorbing approximately 70% of the available energy, while the third methodology generated unduly non-conservative results. residual flexural properties of previously impact damaged laminate specimens showed that the modulus of elasticity is the most valuable parameter for structural integrity monitoring of the hybrid composite.
Local order structure of a-SiOxNy:H grown by PECVD
Scopel, W.L.;Fantini, M.C.A.;Alayo, M.I.;Pereyra, I.;
Brazilian Journal of Physics , 2002, DOI: 10.1590/S0103-97332002000200033
Abstract: in this work we study the structural properties of amorphous oxynitride films (a-sioxny), grown by plasma enhanced chemical vapour deposition (pecvd)at 320° c. the films were deposited at different ow ratio of n2o and sih4. the atomic composition of the samples was determined by means of rutherford backscattering spectrometry (rbs). the local order structure was studied by x-ray absorption spectroscopy (xas) and the chemical bondings were investigated by fourier transform infrared (ftir) spectroscopy. the results evidence a tetrahedric arrangement of the oxynitride network. the tetrahedrons are similiar to sio3n for x values between 1.43 and 1.64. for x values higher than 1.64 the tetrahedrons are similar to sio4.
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