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Search Results: 1 - 10 of 423 matches for " Davey PG "
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Optimal management of urinary tract infections in older people
Beveridge L, Davey PG, Phillips G, McMurdo MET
Clinical Interventions in Aging , 2011, DOI: http://dx.doi.org/10.2147/CIA.S13423
Abstract: imal management of urinary tract infections in older people Review (12223) Total Article Views Authors: Beveridge L, Davey PG, Phillips G, McMurdo MET Published Date June 2011 Volume 2011:6 Pages 173 - 180 DOI: http://dx.doi.org/10.2147/CIA.S13423 Louise A Beveridge1, Peter G Davey2, Gabby Phillips3, Marion ET McMurdo1 1Ageing and Health, Division of Medical Sciences, Ninewells Hospital and Medical School, 2Health Informatics Centre, University of Dundee, 3Medical Microbiology Department, NHS Tayside Abstract: Urinary tract infections (UTI) occur frequently in older people. Unfortunately, UTI is commonly overdiagnosed and overtreated on the basis of nonspecific clinical signs and symptoms. The diagnosis of a UTI in the older patient requires the presence of new urinary symptoms, with or without systemic symptoms. Urinalysis is commonly used to diagnose infection in this population, however, the evidence for its use is limited. There is overwhelming evidence that asymptomatic bacteriuria should not be treated. Catheter associated urinary tract infection accounts for a significant amount of hospital-associated infection. Indwelling urinary catheters should be avoided where possible and alternatives sought. The use of narrow spectrum antimicrobial agents for urinary tract infection is advocated. Local guidelines are now widely used to reflect local resistance patterns and available agents. Guidelines need to be updated to reflect changes in antimicrobial prescribing and a move from broad to narrow spectrum antimicrobials.
Optimal management of urinary tract infections in older people
Beveridge L,Davey PG,Phillips G,McMurdo MET
Clinical Interventions in Aging , 2011,
Abstract: Louise A Beveridge1, Peter G Davey2, Gabby Phillips3, Marion ET McMurdo11Ageing and Health, Division of Medical Sciences, Ninewells Hospital and Medical School, 2Health Informatics Centre, University of Dundee, 3Medical Microbiology Department, NHS TaysideAbstract: Urinary tract infections (UTI) occur frequently in older people. Unfortunately, UTI is commonly overdiagnosed and overtreated on the basis of nonspecific clinical signs and symptoms. The diagnosis of a UTI in the older patient requires the presence of new urinary symptoms, with or without systemic symptoms. Urinalysis is commonly used to diagnose infection in this population, however, the evidence for its use is limited. There is overwhelming evidence that asymptomatic bacteriuria should not be treated. Catheter associated urinary tract infection accounts for a significant amount of hospital-associated infection. Indwelling urinary catheters should be avoided where possible and alternatives sought. The use of narrow spectrum antimicrobial agents for urinary tract infection is advocated. Local guidelines are now widely used to reflect local resistance patterns and available agents. Guidelines need to be updated to reflect changes in antimicrobial prescribing and a move from broad to narrow spectrum antimicrobials.Keywords: urinary tract infection, elderly, review
A case of an ectopic cervical thymic cyst  [PDF]
Simon Davey, Janet McNally
Case Reports in Clinical Medicine (CRCM) , 2013, DOI: 10.4236/crcm.2013.22041
Abstract:

Ectopic cervical thymic cysts are uncommon lesions and definitive preoperative diagnosis is not always possible. Surgical excision is recommended due to the small but possible chance of malignant degeneration in adulthood. We present a case of a nine year old boy with an asymptomatic lesion in his neck, discuss the differential diagnoses of such lesions and treatment considerations.

Women Literacy and Infant Feeding Practices in Rural Integrated Child Development Scheme (ICDS) Block of Delhi
Davey Sanjeev , Davey Anuradha
National Journal of Community Medicine , 2012,
Abstract: Background: Infant feeding practices have significant effect on the child nutrition, which largely dependent upon the mothers correct knowledge and awareness for the same. Objective: To find out effect of rural women empowerment through literacy on infant feeding practices in an ICDS block. Material and Methodology: Interview of the mothers of registered children up to 6 years in the rural ICDS block for the feeding practices and recording of the weight of those registered children by the salter weighing scale for their nutritional status. Results: Three fourth of the children had received ceremonial feed in the form of honey or gutti and 40 percent of the mothers in our study has discarded colostrums, considering it as a€ bad milka€ . Exclusive breast feeding was received by 34.6% children. As literacy level of mothers increased the nutritional status of children was better. This could be because most of the women who are middle school passed or above are non working, so are able to give more time for care and feeding practices. The Severe malnutrition (grade III and IV) was evident only in illiterate category of mothers, where 58.7% women were working in unskilled or semiskilled job outside home. Conclusion: Women living in chronic hunger are forced to unskilled jobs for income generation for the family, thereby influencing the feeding practices of their children. In such scenario AWCs and AWWs can be a unique opportunity with their focused approach to take care of severe and moderate malnutrition.
Simultaneous reconstructive surgery for radical mastectomy
PG Robb
Breast Cancer Research , 2005, DOI: 10.1186/bcr1214
Abstract: The increased use of postmastectomy radiation therapy in patients with early-stage breast cancer has increased the complexity of planning for immediate breast reconstruction. Studies have evaluated the outcomes of breast reconstruction performed before radiation therapy, revealing a high incidence of complications and poor aesthetic outcomes [3]. Moreover, immediate breast reconstruction can interfere with the delivery of postmastectomy radiation therapy. Multidisciplinary breast conference identification of early breast cancer patients at high risk for radiation therapy has evolved a unique and highly successful 'delayed immediate' reconstruction [4] approach that preserves the aesthetic outcomes of immediate reconstruction and avoids radiation injury to the reconstructive tissues. This is accomplished by utilizing a filled subpectoral tissue expander to temporarily preserve the breast skin envelope until the final tissue pathology is confirmed and the patient either goes on to definitive reconstruction or to radiation therapy with the expander deflated. A total of 28 high-risk early breast cancer patients have undergone the delayed immediate approach with 20 patients (71%) not ultimately requiring radiation therapy. Nineteen patients in the non-radiated group (95%) have now completed definitive reconstruction, primarily with the use of autologous tissues. The eight patients who required radiation have completed the radiation therapy and six (75%) have undergone tissue re-expansion and skin-preserving delayed reconstruction designed to be as similar in outcome to immediate reconstruction as possible. The complication rate for the initial expander placement at the time of mastectomy was 18% for all patients. Five nonradiated patients (25%) had complications in the second stage of definitive reconstruction and one patient (17%) following radiation therapy had complications in the skin-preserving delayed reconstruction.Finally, following the successful experience of t
The Nile river question and the Riparian States: Contextualising Uganda's Foreign Policy Interests
PG Okoth
African Sociological Review / Revue Africaine de Sociologie , 2007,
Abstract:
Out-of-pocket payment for health services: constraints and implications for government employees in Abakaliki, Ebonyi state, South east Nigeria
PG Oyibo
African Health Sciences , 2011,
Abstract: Background: Each year, 100 million people are impoverished globally as a result of expenditure on health. Objective: To assess the constraints and implications of out-of-pocket payment for health services among government employees in Abakaliki, Ebonyi State, south east Nigeria. Method: This was a cross-sectional descriptive study. The study instrument was a pre-tested, semi-structured self administered questionnaire. Results: Over half of the respondents (62.8 %) reported a history of illness in their household in the preceding four weeks before the study. Sixty-nine percent of these respondents relied on out-of-pocket payment in order to pay for health services at the moment of seeking medical treatment for themselves or their dependants; while 28.4 % and 2.6 % relied on a prepayment package (National Health Insurance Scheme) and borrowed money respectively to pay for health services at the moment of seeking medical treatment for themselves or their dependants. The vast majority of respondents (63.6 %) who relied on out-of-pocket payment reported their difficulties in accessing quality health care services as a result of financial hardship at the moment of seeking medical treatment. Most of them (47.7 %) resolved to self medication, while 28.4 %, 17.1 % and 6.8 % of them delayed seeking health care, patronized herbalists and ignored their illness respectively. Conclusion: This study brings to the fore the fact that most government employees and their dependants in Abakaliki have difficulties in accessing quality health care services via paying for them out-of-pocket.
The tumor microenvironment in prostate cancer: elucidating molecular pathways for therapy development
Corn PG
Cancer Management and Research , 2012, DOI: http://dx.doi.org/10.2147/CMAR.S32839
Abstract: umor microenvironment in prostate cancer: elucidating molecular pathways for therapy development Review (2185) Total Article Views Authors: Corn PG Published Date July 2012 Volume 2012:4 Pages 183 - 193 DOI: http://dx.doi.org/10.2147/CMAR.S32839 Received: 11 April 2012 Accepted: 02 May 2012 Published: 25 July 2012 Paul G Corn Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, Houston, TX, USA Abstract: Mechanisms leading to the development of virulent prostate cancer are not confined to the cancer epithelial cell, but also involve the tumor microenvironment. Multiple signaling pathways exist between epithelial cells, stromal cells, and the extracellular matrix to support tumor progression from the primary site to regional lymph nodes and distant metastases. Prostate cancers preferentially metastasize to the skeleton, prompting considerable research effort into understanding the unique interaction between prostate cancer epithelial cells and the bone microenvironment. This effort has led to the discovery that signaling pathways involved in normal prostate and bone development become dysregulated in cancer. These pathways stimulate excessive cell growth and neovascularization, impart more invasive properties to epithelial cells, weaken antitumor immune surveillance, and promote the emergence of castrate-resistant disease. An improved understanding of the complex relationship between cancer epithelial cells and the organ-specific microenvironments with which they interact has created a powerful opportunity to develop novel therapies.
Endoscopic Ultrasonography: Impact in Diagnosis, Staging and Management of Pancreatic Tumors. An Overview
Arcidiacono PG
JOP Journal of the Pancreas , 2004,
Abstract:
The tumor microenvironment in prostate cancer: elucidating molecular pathways for therapy development
Corn PG
Cancer Management and Research , 2012,
Abstract: Paul G CornDepartment of Genitourinary Medical Oncology, MD Anderson Cancer Center, Houston, TX, USAAbstract: Mechanisms leading to the development of virulent prostate cancer are not confined to the cancer epithelial cell, but also involve the tumor microenvironment. Multiple signaling pathways exist between epithelial cells, stromal cells, and the extracellular matrix to support tumor progression from the primary site to regional lymph nodes and distant metastases. Prostate cancers preferentially metastasize to the skeleton, prompting considerable research effort into understanding the unique interaction between prostate cancer epithelial cells and the bone microenvironment. This effort has led to the discovery that signaling pathways involved in normal prostate and bone development become dysregulated in cancer. These pathways stimulate excessive cell growth and neovascularization, impart more invasive properties to epithelial cells, weaken antitumor immune surveillance, and promote the emergence of castrate-resistant disease. An improved understanding of the complex relationship between cancer epithelial cells and the organ-specific microenvironments with which they interact has created a powerful opportunity to develop novel therapies.Keywords: prostate cancer, molecular signaling, prostate cancer therapy, tumor microenvironment, castrate-resistant prostate cancer
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