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Histo-anatomy of the stem of Solanum tuberosum L.
Monica SIPOS,Manuela ILEA,Iosif MOLNAR,Daniel BUNTA
Analele Universitatii din Oradea, Fascicula Biologie , 2008,
Abstract: The paper reveals the anatomical structure of the stem of Solanum tuberosum L. in the incipient stages of the ontogenetic development (the popular denomination sprout”). Cross sections of the stem of this species were performed. The appearance of the secondary structure – even in this early ontogenetic stage – was confirmed by the presence of the cambium and the tissues generated by this. As a result, at the potato, the purely primary structure of the stem is of a short duration.
Asymmetric nuclear matter in the relativistic mean field approach with vector cross-interaction
Juraj Kotulic Bunta,Stefan Gmuca
Physics , 2003, DOI: 10.1103/PhysRevC.68.054318
Abstract: Asymmetric nuclear matter is studied in the frame of relativistic mean-field theory, using scalar-isoscalar sigma, vector-isoscalar omega meson together with their selfinteractions, vector-isovector rho meson with its cross-interaction with omega meson too, and scalar-isovector delta meson as degrees of freedom. The model is used to parameterize the nuclear matter properties results calculated by more fundamental Dirac-Brueckner-Hartree-Fock theory and thus to provide an effective DBHF model applicable also to finite nuclei. Vector omega-rho cross-interaction seems to be an useful degree of freedom for describing of the asymmetric nuclear matter, mostly due to its impact on density dependence of the symmetry energy.
Hyperons in a relativistic mean-field approach to asymmetric nuclear matter
Juraj Kotulic Bunta,Stefan Gmuca
Physics , 2004, DOI: 10.1103/PhysRevC.70.054309
Abstract: Relativistic mean-field theory with $\delta$ meson, nonlinear isoscalar self-interactions and isoscalar-isovector cross interaction terms with parametrizations obtained to reproduce Dirac-Brueckner-Hartree-Fock calculations for nuclear matter is used to study asymmetric nuclear matter properties in $\beta$-equilibrium, including hyperon degrees of freedom and (hidden) strange mesons. Influence of cross interaction on composition of hyperon matter and electron chemical potential is examined. Softening of nuclear equation of state by the cross interactions results in lowering of hyperonization, although simultaneously enhancing a hyperon-induced decrease of the electron chemical potential, thus indicating further shift of a kaon condensate occurence to higher densities.
RPEL Proteins Are the Molecular Targets for CCG-1423, an Inhibitor of Rho Signaling
Ken’ichiro Hayashi, Bunta Watanabe, Yoshiaki Nakagawa, Saki Minami, Tsuyoshi Morita
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0089016
Abstract: Epithelial–msenchymal transition (EMT) is closely associated with cancer and tissue fibrosis. The nuclear accumulation of myocardin-related transcription factor A (MRTF-A/MAL/MKL1) plays a vital role in EMT. In various cells treated with CCG-1423, a novel inhibitor of Rho signaling, the nuclear accumulation of MRTF-A is inhibited. However, the molecular target of this inhibitor has not yet been identified. In this study, we investigated the mechanism of this effect of CCG-1423. The interaction between MRTF-A and importin α/β1 was inhibited by CCG-1423, but monomeric G-actin binding to MRTF-A was not inhibited. We coupled Sepharose with CCG-1423 (CCG-1423 Sepharose) to investigate this mechanism. A pull-down assay using CCG-1423 Sepharose revealed the direct binding of CCG-1423 to MRTF-A. Furthermore, we found that the N-terminal basic domain (NB) of MRTF-A, which acts as a functional nuclear localization signal (NLS) of MRTF-A, was the binding site for CCG-1423. G-actin did not bind to CCG-1423 Sepharose, but the interaction between MRTF-A and CCG-1423 Sepharose was reduced in the presence of G-actin. We attribute this result to the high binding affinity of MRTF-A for G-actin and the proximity of NB to G-actin-binding sites (RPEL motifs). Therefore, when MRTF-A forms a complex with G-actin, the binding of CCG-1423 to NB is expected to be blocked. NF-E2 related factor 2, which contains three distinct basic amino acid-rich NLSs, did not bind to CCG-1423 Sepharose, but other RPEL-containing proteins such as MRTF-B, myocardin, and Phactr1 bound to CCG-1423 Sepharose. These results suggest that the specific binding of CCG-1423 to the NLSs of RPEL-containing proteins. Our proposal to explain the inhibitory action of CCG-1423 is as follows: When the G-actin pool is depleted, CCG-1423 binds specifically to the NLS of MRTF-A/B and prevents the interaction between MRTF-A/B and importin α/β1, resulting in inhibition of the nuclear import of MRTF-A/B.
Elevated Incidence of Fractures in Solid-Organ Transplant Recipients on Glucocorticoid-Sparing Immunosuppressive Regimens
B. J. Edwards,A. Desai,J. Tsai,H. Du,G. R. Edwards,A. D. Bunta,A. Hahr,M. Abecassis,S. Sprague
Journal of Osteoporosis , 2011, DOI: 10.4061/2011/591793
Abstract: This study was conducted to assess the occurrence of fractures in solid-organ transplant recipients. Methods. Medical record review and surveys were performed. Patients received less than 6 months of glucocorticoids. Results. Of 351 transplant patients, 175 patients provided fracture information, with 48 (27.4%) having fractured since transplant (2–6 years). Transplants included 19 kidney/liver (50% male), 47 kidney/pancreas (53% male), 92 liver (65% male), and 17 pancreas transplants (41% male). Age at transplant was 50.8±10.3 years. Fractures were equally seen across both genders and transplant types. Calcium supplementation (=94) and bisphosphonate therapy (=52) were observed, and an association with a lower risk of fractures was noted for bisphosphonate users (OR=0.45 95% C.I. 0.24, 0.85). Fracture location included 8 (16.7%) foot, 12 (25.0%) vertebral, 3 (6.3%) hand, 2 (4.2%) humerus, 5 (10.4%) wrist, 10 (20.8%) fractures at other sites, and 7 (14.6%) multiple fractures. The estimated relative risk of fracture was nearly seventeen-times higher in male liver transplant recipients ages 45–64 years compared with the general male population, and comparable to fracture rates on conventional immunosuppressant regimens. Conclusion. We identify a high frequency of fractures in transplant recipients despite limited glucocorticoid use.
Elevated Incidence of Fractures in Solid-Organ Transplant Recipients on Glucocorticoid-Sparing Immunosuppressive Regimens
B. J. Edwards,A. Desai,J. Tsai,H. Du,G. R. Edwards,A. D. Bunta,A. Hahr,M. Abecassis,S. Sprague
Journal of Osteoporosis , 2011, DOI: 10.4061/2011/591793
Abstract: This study was conducted to assess the occurrence of fractures in solid-organ transplant recipients. Methods. Medical record review and surveys were performed. Patients received less than 6 months of glucocorticoids. Results. Of 351 transplant patients, 175 patients provided fracture information, with 48 (27.4%) having fractured since transplant (2–6 years). Transplants included 19 kidney/liver (50% male), 47 kidney/pancreas (53% male), 92 liver (65% male), and 17 pancreas transplants (41% male). Age at transplant was years. Fractures were equally seen across both genders and transplant types. Calcium supplementation ( ) and bisphosphonate therapy ( ) were observed, and an association with a lower risk of fractures was noted for bisphosphonate users ( 95% C.I. 0.24, 0.85). Fracture location included 8 (16.7%) foot, 12 (25.0%) vertebral, 3 (6.3%) hand, 2 (4.2%) humerus, 5 (10.4%) wrist, 10 (20.8%) fractures at other sites, and 7 (14.6%) multiple fractures. The estimated relative risk of fracture was nearly seventeen-times higher in male liver transplant recipients ages 45–64 years compared with the general male population, and comparable to fracture rates on conventional immunosuppressant regimens. Conclusion. We identify a high frequency of fractures in transplant recipients despite limited glucocorticoid use. 1. Introduction Within the past 3 decades, organ transplantation has become an established therapy for end-stage diseases of the kidney, liver, and lung. Survival after solid-organ transplantation has improved markedly mainly because of the addition of calcineurin inhibitors, cyclosporine A (CsA), and tacrolimus, to posttransplantation immunosuppressive regimens. With improved survival has come a greater appreciation of complications such as osteoporosis and fractures that negatively influence patients’ quality of life. The pathogenesis of transplantation osteoporosis is complex and incompletely understood. It is probably related to a combination of noxious effects to the skeleton that occur both before and after organ transplantation. Cardiac, kidney, lung, and liver failure each have unique pathophysiologies that influence bone and mineral metabolism before transplantation. Additional factors such as aging, nutritional deficiencies, immobility, diabetes mellitus, tobacco, and alcohol may affect the skeletons of these transplant recipients before and after transplantation. In the posttransplant period, patients are then subjected to a drug regimen that usually includes high doses of glucocorticoids, the most common cause of secondary
Poetry Teaching and Multimodality: Theory into Practice  [PDF]
Daniel Xerri
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.34077
Abstract: This article discusses the theoretical concepts underpinning a multimodal approach to poetry teaching and considers a number of ways in which this can be adopted in practice. It discusses what is entailed by the concept of multimodality and examines the claims made about the benefits of employing a multimodal approach. It reviews the literature on multimodality and examines how teachers may blend a variety of techniques and resources in order not just to engage their students with poetry but also to activate language learning. In particular, this article examines how by tapping students’ visual and digital literacy skills they are enabled to create video poems, podcasts, hypertexts and wikis, all of which represent new ways of using language and experiencing poetry. Through constant reference to the research carried out so far, this article seeks to show how by means of a multimodal approach poetry can act as a springboard for the development of students’ language proficiency and creative engagement.
Mathematical Derivation of Angular Momenta in Quantum Physics  [PDF]
Daniel Grucker
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.47125
Abstract:

For a two-dimensional complex vector space, the spin matrices can be calculated directly from the angular momentum commutator definition. The 3 Pauli matrices are retrieved and 23 other triplet solutions are found. In the three-dimensional space, we show that no matrix fulfills the spin equations and preserves the norm of the vectors. By using a Clifford geometric algebra it is possible in the four-dimensional spacetime (STA) to retrieve the 24 different spins 1/2. In this framework, spins 1/2 are rotations characterized by multivectors composed of 3 vectors and 3 bivectors. Spins 1 can be defined as rotations characterized by 4 vectors, 6 bivectors and 4 trivectors which result in unit multivectors which preserve the norm. Let us note that this simple derivation retrieves the main spin properties of particle physics.

Contribution of Vertical Farms to Increase the Overall Energy Efficiency of Urban Agglomerations  [PDF]
Podmirseg Daniel
Journal of Power and Energy Engineering (JPEE) , 2014, DOI: 10.4236/jpee.2014.24013
Abstract: The 21st century keeps huge challenges for the system “city”. Shortage of resources and world population growth forces architects to think in spaces with increasingly more structural linkages. No era has shaped the system of a city like the oil age did. Its grown structures are dependent from cheap and easy to produce petroleum. The postmodern city, facing the end of cheap and abundant oil, is now dependent from this finite resource. To minimize the dependency from hydrocarbon energy it is necessary to increase urban density, to switch to renewable energy production and to create new spaces for multifunctional purposes. An essential problem of urban agglomeration, though, is the fact that distances between food production and consumption have increased drastically in the last fifty years. Cheap oil made it possible to implement a global food transportation
network and it also supported intensive monocultural food production. Today’s food no more gets bought from local markets, but from labels. Its value is dependent from the brand-image, represented from the tertiary sector. The end of cheap fossil fuels carries a huge potential for architects and urban planners—we can move away from representing abstract, non-spatial processes and identities but creating spaces for dynamic local interactions. A promising typus for this might be the Vertical Farm.
The Computational Theory of Intelligence: Information Entropy  [PDF]
Daniel Kovach
International Journal of Modern Nonlinear Theory and Application (IJMNTA) , 2014, DOI: 10.4236/ijmnta.2014.34020
Abstract: This paper presents an information theoretic approach to the concept of intelligence in the computational sense. We introduce a probabilistic framework from which computation alintelligence is shown to be an entropy minimizing process at the local level. Using this new scheme, we develop a simple data driven clustering example and discuss its applications.
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