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Search Results: 1 - 6 of 6 matches for " Dalina OCHETAN "
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Silvia PUIU,Bogdan Andrei BUDIC?,Dalina OCHETAN,Florin BUDIC?
Management & Marketing , 2012,
Abstract: The export of furniture always represented a profitable domain for Romania. The current research provides a pertinent analysis with numbers for the situation of the export in the furniture industry. The article proposes a few important measures that should be considered by the Romanian manufacturers of furniture in the further period, in order to reestablish the export activity and hence the wood processing industry.
Alexandra Maria FIRA,Claudiu Traian Mircea OCHETAN
Management & Marketing , 2012,
Abstract: The main objective of our paper is the study of human resources management in SMEs in Dolj County. Through our research we emphasize and demonstrate the importance of human resources in the maintaining process of stability and in perpetuating the viability of this dynamic sector – the one of SMEs. Thus, the theoretical concepts are grounded both through theory and national and international practices, and through the actual data obtained from the research that will be carried out in the field. The practical implications of our research reflect in the analysis and interpretation of the research results carried out on 516 employees from SMEs in Dolj County, as well as in the recommendations elaborated based on a set of variables established according to the importance of the employees’ role in the enterprises as bearers of initiative and generators of innovation. Therefore, we have reached the conclusion that involving employees in the decision making process is an important factor for the survival and progress of SMEs.
Immunoglobulin G Determination in Human Serum and Milk Using an Immunosensor of New Conception Fitted with an Enzyme Probe as Transducer
Luigi Campanella,Dalina Lelo,Elisabetta Martini,Mauro Tomassetti
Sensors , 2008, DOI: 10.3390/s8106727
Abstract: To completely overcome the problem of the presence of urea in the serum, which can be the cause (especially at low immunoglobulin G concentrations) of a small but non negligible interference in the enzyme reaction of the enzymatic marker, when the measurement was performed by a potentiometric immunosensor that we constructed and characterized in previous work, and which used urease as marker, we have now constructed an entirely different and highly innovative immunosensor. This new device uses the enzyme alkaline phosphatase as marker, sodium phenylphosphate as substrate but above all, a tyrosinase biosensor obtained by coupling a Clark type gas diffusion amperometric electrode and the tyrosinase enzyme, immobilized in a cellulose triacetate membrane, as transducer. After optimizing the ‘competitive’ measurement procedures, the new immunosensor was used to determine both HIgG and the anti-HIgG, with a limit of detection (LOD) of the order of 3x10-11 M. Clearly this highly innovative construction geometry makes the immunosensor extremely selective. This makes it possible to determine immunoglobulin G both in human serum and milk without the slightest interference by any urea present in these biological matrixes.
Dalina Adan,Suhaila Sapari,Siti Nadiah Halim,Bohari M. Yamin
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812028218
Abstract: The title compound, C20H19Cl2N5O2S, was obtained from the reaction of 4-chlorobenzoyl isothiocyanate with diethylenetriamine. The imidazolidine ring is slightly twisted with an N—C—C—N torsion angle of 15.4 (4)°, while the thiourea moiety maintains its trans–cis geometry. The molecule is stabilized by intramolecular N—H...O hydrogen bonds. The crystal structure features N—H...O, N—H...S and C—H...O hydrogen bonds and π–π interactions between benzene rings with a centroid–centroid distance of 3.607 (3) .
Interleukin-1 involved in Apoptosis of Beta-Thalassemia/Hemoglobin E Erythroid Progenitor Cells
Umesh Prasad Gupta, Pranee Fucharoen, Dalina I Tanyong
Asian Journal of Medical Sciences , 2012, DOI: 10.3126/ajms.v3i4.6805
Abstract: Objective: The major pathophysiological features of β-thalassemia are anemia and ineffective erythropoiesis. Ineffective erythropoiesis has been shown by an intense marrow erythroid hyperplasia and increased apoptosis during basophilic to orthochromatic normoblast stages. Some cytokines like interferon-γ (IFN-γ), tumor necrosis factor α (TNF-α) and interleukin-1 (IL-1) have been found to involved in apoptosis. Although the pro-apoptotic activity of IFN-γ and TNF-α is well documented, there are only few studies on IL-1, especially on erythroid lineage. In this in vitro study, the role of cytokine IL-1α and IL-1β in apoptosis of erythroid progenitor cells from β- thalassemia/HbE patients was assessed.
Diversity of Virulence Phenotypes among Type III Secretion Negative Pseudomonas aeruginosa Clinical Isolates
Jonida Toska, Yan Sun, Dalina Alvarez Carbonell, Altreisha N. -S. Foster, Michael R. Jacobs, Eric Pearlman, Arne Rietsch
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0086829
Abstract: Pseudomonas aeruginosa is a frequent cause of acute infections. The primary virulence factor that has been linked to clinical disease is the type III secretion system, a molecular syringe that delivers effector proteins directly into host cells. Despite the importance of type III secretion in dictating clinical outcomes and promoting disease in animal models of infections, clinical isolates often do not express the type III secretion system in vitro. Here we screened 81 clinical P. aeruginosa isolates for secretion of type III secretion system substrates by western blot. Non-expressing strains were also subjected to a functional test assaying the ability to intoxicate epithelial cells in vitro, and to survive and cause disease in a murine model of corneal infection. 26 of 81 clinical isolates were found to be type III secretion negative by western blot. 17 of these 26 non-expressing strains were tested for their ability to cause epithelial cell rounding. Of these, three isolates caused epithelial cell rounding in a type III secretion system dependent manner, and one strain was cytotoxic in a T3SS-independent manner. Five T3SS-negative isolates were also tested for their ability to cause disease in a murine model of corneal infection. Of these isolates, two strains caused severe corneal disease in a T3SS-independent manner. Interestingly, one of these strains caused significant disease (inflammation) despite being cleared. Our data therefore show that P. aeruginosa clinical isolates can cause disease in a T3SS-independent manner, demonstrating the existence of novel modifiers of clinical disease.
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