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Search Results: 1 - 10 of 189794 matches for " Dalglish G "
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Scientific Respiratory Symposium, Paris June 2010
Dalglish G, Priestley G
Journal of Asthma and Allergy , 2011, DOI: http://dx.doi.org/10.2147/JAA.S20631
Abstract: ientific Respiratory Symposium, Paris June 2010 Expert Opinion (3746) Total Article Views Authors: Dalglish G, Priestley G Published Date June 2011 Volume 2011:4 Pages 61 - 76 DOI: http://dx.doi.org/10.2147/JAA.S20631 Gavin Dalglish, Graham Priestley Horizon Medical Publishing, Chichester, UK Abstract: At a 2010 Respiratory Symposium in Paris, chaired by Professors Bousquet and Roche of the University of Paris, recent trends in research, therapy and treatment guidelines for asthma and chronic obstructive pulmonary disease (COPD) were reviewed and discussed by a faculty of expert European and US respiratory physicians. This article reviews five key clinical presentations with particular emphasis given to the importance of small airways in the pathology and treatment of asthma and COPD. Further analysis of the economics of treatment in Europe and the US shows a wide variance in direct and indirect costs.
Scientific Respiratory Symposium, Paris June 2010
Dalglish G,Priestley G
Journal of Asthma and Allergy , 2011,
Abstract: Gavin Dalglish, Graham PriestleyHorizon Medical Publishing, Chichester, UKAbstract: At a 2010 Respiratory Symposium in Paris, chaired by Professors Bousquet and Roche of the University of Paris, recent trends in research, therapy and treatment guidelines for asthma and chronic obstructive pulmonary disease (COPD) were reviewed and discussed by a faculty of expert European and US respiratory physicians. This article reviews five key clinical presentations with particular emphasis given to the importance of small airways in the pathology and treatment of asthma and COPD. Further analysis of the economics of treatment in Europe and the US shows a wide variance in direct and indirect costs.Keywords: COPD, asthma, small airways, real-life clinical practice
Flavonoids from the leaves of Deguelia utilis (Leguminosae): structural elucidation and neuroprotective properties
Oliveira, Dalglish G. de;Almeida, Cecília M. C. de;Silva, Consuelo Y. Y. e;Arruda, Mara S. P.;Arruda, Alberto C.;Lopes, Dielly C. F.;Yamada, Elizabeth S.;Costa, Edmar T. da;M. Filho, Arnaldo Jorge;Silva, Milton N. da;
Journal of the Brazilian Chemical Society , 2012, DOI: 10.1590/S0103-50532012005000065
Abstract: five new flavonoids, 5,3'-dihydroxy-4'-methoxy-2'',2''-dimethylchromene-(5'',6'':6,7)dihydroflavonol (1), 5,3'-dihydroxy-7,4'-dimethoxy-6,8-dimethylallyl-dihydroflavonol (2), 5,3'-dihydroxy-4'-methoxy-8-allyl-2'',2''-dimethylchromene-(5'',6'':6,7) flavanone (3), 5,3'-dihydroxy-7,4'-dimethoxy-6,8-dimethylallyl-flavanone (4), 3,5,3'-trihydroxy-7,4'-dimethoxy6,8-dimethylallyl-flavanol (5), together with the stilbenes 4-methoxylonchocarpene (6) and lonchocarpene (7) were isolated from the leaves of deguelia utilis. their chemical structures were established on the basis of nmr (nuclear magnetic resonance) spectral data and hresitof-ms (electrospray ionization-high resolution time-of-flight mass spectrometry). also, in order to investigate potential cytoprotective effects of these flavonoids, we used a fraction eluted with hexane:etoac containing all seven flavonoids, in an in vitro model of neurodegeneration, using hippocampal primary cultures from neonatal (pnd2-p3) rats exposed to rotenone, a mitochondrial complex i inhibitor. there was a significant reduction in cell viability (19.4 ± 1.6%) when the cultures were exposed to 30 nmol l-1 rotenone for 72 h. concomitant exposure of the cultures to the fr3 (5 μg ml-1) and 30 nmol l-1 rotenone resulted in values of cell viability similar to control groups (99.6 ± 4.8%), strongly suggesting a cytoprotective effect for this flavonoid-rich fraction.
Lipid-Lowering Effects of Ethyl 2-Phenacyl-3-aryl-1H-pyrrole- 4-carboxylates in Rodents
Justin M. Holub,Kathy O'Toole-Colin,Adam Getzel,Anthony Argenti,Michael A. Evans,Daniel C. Smith,Gerard A. Dalglish,Shahzad Rifat,Donna L. Wilson,Brett M. Taylor,Ulander Miott,Josephine Glersaye,Kam Suet Lam,Bryan J. McCranor,Joshua D. Berkowitz,Robert B. Miller,John R. Lukens,Keith Krumpe,John T. Gupton,Bruce S. Burnham
Molecules , 2004, DOI: 10.3390/90300134
Abstract: A series of substituted 2-phenacyl-3-phenyl-1H-pyrrole-4-carboxylates were prepared from substituted acetophenones in 6 steps. The final condensations between a chloroenal and an aminoketone were carried out under neutral conditions in parallel to yield the series listed below. Selected pyrrole derivatives proved to be potent hypolipidemic agents lowering serum triglyceride concentrations in CF-1 male mice after 14 days of I.P. administration. One agent orally lowered serum cholesterol in Sprague-Dawley male rats at 2mg/kg/day after 14 days. The agents demonstrated a lowering of mouse serum LDL- cholesterol levels and selected compounds showed an elevation of serum HDL-cholesterol levels. The cholesterol concentrations in the liver were raised while the cholesterol and triglyceride contents of the aorta were significantly lowered by the selected trisubstituted pyrrole.
A Characterization of the Members of a Subfamily of Power Series Distributions  [PDF]
G. Nanjundan
Applied Mathematics (AM) , 2011, DOI: 10.4236/am.2011.26099
Abstract: This paper discusses a characterization of the members of a subfamily of power series distributions when their probability generating functions satisfy the functional equation where a, b and c are constants and is the derivative of f.
Double Negative Left-Handed Metamaterials for Miniaturization of Rectangular Microstrip Antenna  [PDF]
G. Singh
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2010, DOI: 10.4236/jemaa.2010.26044
Abstract: In this paper, I have explored a significant concept for the miniaturization of microstrip patch antenna configuration by using the double negative (DNG) left-handed Metamaterials, which have dielectric permittivity and magnetic permeability both negative, simultaneously. It is achieved through the concept of phase-compensation by thin slab consist of the double positive (DPS) material, which have dielectric permittivity and magnetic permeability both positive, simultaneously and DNG metamaterials as a substrate of the microstrip patch antenna. By combining the DNG metamaterial slab with the slab made of DPS materials form a cavity resonator whose dispersion relation is independent of the sum of thickness of the slabs filling this cavity but it depends on the ratio of their thicknesses. This cavity constitutes by DPS and DNG material is used as substrate of the microstrip antennas and the DNG material slab is behave as phase compensator.
Dynamic and Configurational Approach to the Glass Transition by Nanoscale Cooperativity  [PDF]
G. Romeo
Open Journal of Biophysics (OJBIPHY) , 2012, DOI: 10.4236/ojbiphy.2012.23012
Abstract: Here we examine the findings obtained for disaccharide/water mixtures near glass transition that involves cooperative relaxation features on kinetic by viscosity and on thermodynamic behaviour by neutron scattering. Then to address cooperative phenomena that mitigate the Debye-Waller behaviour we invoke Adam-Gibbs’ idea of a cooperative rearranging region. Neutron results suggest that the excess mean square displacement behaves as free volume and is closely connected to an elementary step of the structural relaxation. Then viscosity data evidence a breakdown of the Einstein-Debye relation, decoupling attributed to the intermolecular cooperativity.
Confidence Level Estimator of Cosmological Parameters  [PDF]
G. Sironi
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.329157
Abstract: Cosmological Models frequently suggest the existence of physical, quantities, e.g. dark energy, we cannot yet observe and measure directly. Their values are obtained indirectly setting them equal to values and accuracy of the associated model parameters which best fit model and observation. Apparently results are so accurate that some researchers speak of precision cosmology. The accuracy attributed to these indirect values of the physical quantities however does not include the uncertainty of the model used to get them. We suggest a Confidence Level Estimator to be attached to these indirect measurements and apply it to current cosmological models.
Mitochondrial DNA sequence analysis in Anabantoidei fish  [PDF]
G. Degani
Advances in Biological Chemistry (ABC) , 2013, DOI: 10.4236/abc.2013.33039
Abstract:

The decline of ornamental fish populations in their native habitats due to over-fishing has brought about the development of ornamental fish aquaculture, to which fish of the Anabantoidei suborder are important contributors. The genetic variations among species of this suborder were examined by mitochondrial gene sequencing analysis using the cytochrome b and 12S genes. According to the cytochrome b gene, the most similar strains were Trichogaster trichopterus (gold) and Trichogaster trichopterus (blue) (100%). Trichogaster leerii was less similar to them (86.0%), and an even lower similarity was found between the species T. trichopterus and Trichogaster labiosus (85.6%). The least similarity was observed between Betta betta and the genera Colisa (50.2%) and Trichogaster (60.1%). The phylogenetic trees of 12S and cytochrome b were very similar. According to 12S, the similarity between Trichogaster species was high (91.4% - 100%), and between species of this genus and Colisa lalia, it was lower (88.4%). In conclusion, sequence analyses, based on cytochrome

Estimation of Parameter in a New Truncated Distribution  [PDF]
G. Nanjundan
Open Journal of Statistics (OJS) , 2013, DOI: 10.4236/ojs.2013.34025
Abstract: This paper discusses the estimation of the parameter in a truncated form of a discrete distribution which is analogous to Burr distribution. The maximum likelihood and the moment estimators of the parameter are obtained. Their asymptotic properties are also established.
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