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Search Results: 1 - 10 of 941 matches for " Daejin Hyung "
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Cross-Family Translational Genomics of Abiotic Stress-Responsive Genes between Arabidopsis and Medicago truncatula
Daejin Hyung, Chaeyoung Lee, Jin-Hyun Kim, Dongwoon Yoo, Young-Su Seo, Soon-Chun Jeong, Jai-Heon Lee, Youngsoo Chung, Ki-Hong Jung, Douglas R. Cook, Hong-kyu Choi
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0091721
Abstract: Cross-species translation of genomic information may play a pivotal role in applying biological knowledge gained from relatively simple model system to other less studied, but related, genomes. The information of abiotic stress (ABS)-responsive genes in Arabidopsis was identified and translated into the legume model system, Medicago truncatula. Various data resources, such as TAIR/AtGI DB, expression profiles and literatures, were used to build a genome-wide list of ABS genes. tBlastX/BlastP similarity search tools and manual inspection of alignments were used to identify orthologous genes between the two genomes. A total of 1,377 genes were finally collected and classified into 18 functional criteria of gene ontology (GO). The data analysis according to the expression cues showed that there was substantial level of interaction among three major types (i.e., drought, salinity and cold stress) of abiotic stresses. In an attempt to translate the ABS genes between these two species, genomic locations for each gene were mapped using an in-house-developed comparative analysis platform. The comparative analysis revealed that fragmental colinearity, represented by only 37 synteny blocks, existed between Arabidopsis and M. truncatula. Based on the combination of E-value and alignment remarks, estimated translation rate was 60.2% for this cross-family translation. As a prelude of the functional comparative genomic approaches, in-silico gene network/interactome analyses were conducted to predict key components in the ABS responses, and one of the sub-networks was integrated with corresponding comparative map. The results demonstrated that core members of the sub-network were well aligned with previously reported ABS regulatory networks. Taken together, the results indicate that network-based integrative approaches of comparative and functional genomics are important to interpret and translate genomic information for complex traits such as abiotic stresses.
Treatment of Axillary Osmidrosis Using a Subcutaneous Pulsed Nd-YAG Laser
Daejin Kim,Junhyung Kim,Hyeonjung Yeo,Hyukjun Kwon
Archives of Plastic Surgery , 2012, DOI: http://dx.doi.org/10.5999/aps.2012.39.2.143
Abstract: Background Axillary osmidrosis is characterized by an unpleasant odor, profuse sweating, andin some instances, staining of clothes that may socially and psychologically impair affectedindividuals. Various types of surgical procedures have been developed for the treatment ofaxillary osmidrosis. This study was undertaken to evaluate the effectiveness of subcutaneouspulsed neodymium: yttrium-aluminum-garnet (Nd-YAG) laser treatment for the treatment ofaxillary osmidrosis.Methods Twenty-nine patients with axillary osmidrosis were included in this study. Patientswere categorized according to the results of an axillary malodor grading system, and asubcutaneous pulsed Nd-YAG laser was applied to all patients. The treatment area for theappropriate distribution of laser energy was determined using the iodine starch test (Minor’stest) against a grid pattern composed of 2×2 cm squares. The endpoint of exposure was300 to 500 J for each grid, depending on the preoperative evaluation results. The resultswere evaluated by measurement of axillary malodor both pre- and postoperatively using thegrading system and iodine starch test.Results The average follow-up period was 12.8 months. Nineteen patients had a fair-togoodresult and ten patients had poor results. The postoperative Minor’s test demonstratedthat there were remarkable improvements for patients with mild to moderate symptoms.Complications including superficial second degree burns (n=3) were treated in a conservativemanner. A deep second degree burn (n=1) was treated by a surgical procedure.Conclusions Subcutaneous pulsed Nd-YAG laser has many advantages and is an effectivenoninvasive treatment for mild to moderate axillary osmidrosis.
Ab-initio path integral techniques for molecules
Daejin Shin,Ming-Chak Ho,J. Shumway
Physics , 2006,
Abstract: Path integral Monte Carlo with Green's function analysis allows the sampling of quantum mechanical properties of molecules at finite temperature. While a high-precision computation of the energy of the Born-Oppenheimer surface from path integral Monte Carlo is quite costly, we can extract many properties without explicitly calculating the electronic energies. We demonstrate how physically relevant quantities, such as bond-length, vibrational spectra, and polarizabilities of molecules may be sampled directly from the path integral simulation using Matsubura (temperature) Green's functions (imaginary-time correlation functions). These calculations on the hydrogen molecule are a proof-of-concept, designed to motivate new work on fixed-node path-integral calculations for molecules.
Minimally Invasive Surgery for Pectus Excavatum: Park Technique
Hyung Park
Journal of Clinical and Analytical Medicine , 2011, DOI: 10.4328
Abstract: Pectus excavatum (PE) is the most commonly encountered chest wall deformity which comprises one out of 1,000 live births. Depression of the anterior chest wall due to posterior angulation of the sternum and costal cartilages results in compression of internal thoracic organs as well as aesthetically unpleasant appearance. Multiple surgical techniques have been developed to correct this condition. Ravitch procedure, the technique including the excision of all deformed costal cartilages, division of intercostals bundles from the sternum, and transverse sternal osteotomy, was proposed in 1949 and most widely applied until recently. The Wada technique, principally sternal turnover, has been an alternative procedure. Those invasive techniques involve tedious and bloody operations resulted in a permanent defect of costal cartilages or contracture of the chest wall. Most importantly, a large, unsightly operative scar at the anterior chest is aesthetically dissatisfying. In this study “Minimally Invasive Surgery for Pectus Excavatum: Park Technique” was explained.
Managing Populations with Unimodal Dynamics  [PDF]
Richard Levins, Tamara Awerbuch, Hyung Park
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.410A2009

In this work, we analyzed the impact of interventions on populations which exhibit unimodal dynamics. The six landmarks that characterize the shape of the unimodal reproduction curve f ( x ) of the difference equation, X n+1 = f ( X n ) , are defined and used in order to examine and determine the behavior of dynamics of populations. By using the Li-Yorke criterion for determination of chaos we propose a qualitative intervention rule that can be applied without any explicit population equation. This proposed strategy for intervention brings out many interesting behaviors in population dynamics. A qualitative decision rule can be applied with a straight edge without any population equation and therefore offers a robust strategy for the management of populations.

Etiology and treatment of the inflammatory causes of cystoid macular edema
Hyung Cho, Assumpta Madu
Journal of Inflammation Research , 2009, DOI: http://dx.doi.org/10.2147/JIR.S5706
Abstract: iology and treatment of the inflammatory causes of cystoid macular edema Mini-review (6339) Total Article Views Authors: Hyung Cho, Assumpta Madu Published Date October 2009 Volume 2009:2 Pages 37 - 43 DOI: http://dx.doi.org/10.2147/JIR.S5706 Hyung Cho1, Assumpta Madu1 1Department of Ophthalmology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA Abstract: Cystoid macular edema in its various forms can be considered one of the leading causes of central vision loss in the developed world. It occurs in a wide variety of pathologic conditions and represents the final common pathway of several basic processes. Therapeutic approaches to cystoid macular edema depend on a clear understanding of its contributing pathophysiologic mechanisms. This review will discuss the mechanism of ocular inflammation in cystoid macular edema with a particular focus on the inflammatory causes: post-operative, uveitic, and after laser procedures. A variety of pharmacologic agents targeting inflammatory molecules have been shown to reduce macular edema and improve visual function. However, the long-term efficacy and safety of most new therapies have yet to be established in controlled clinical trials.
Jun-Hyung Ko
International Journal of Economics and Research , 2011,
Abstract: This paper theoretically analyzes the early warning system (EWS) of the IMF based on the principal-agent model. We search for the trade-off of the optimal contract of the IMF under interim intervention and signal noise. The main findings are as follows. First, when the net loss coming from noise under a good fundamental is higher than the net gain by an interim intervention under a bad fundamental, the debtor country exerts less effort as the noise effect becomes larger. Second, when the net loss in a good fundamental is smaller than the net gain in a bad fundamental, an accurate signal may give rise to the moral hazard problem. Third, when the marginal utility by the intervention of the IMF is higher on bad fundamentals than on good fundamentals, the higher ability of the IMF to mitigate the crisis will elicit a weak policy effort from the country. On the other hand, when the economy has higher marginal utility in case of good fundamentals, deeper intervention of the IMF offers an incentive of a stronger policy effort to the country. Fourth, mandating the IMF to care about a country's welfare as well as safeguarding its resources does not necessarily imply that the debtor country will exert less effort
Technology Spillovers between the U.S. and Japan
Jun-Hyung Ko
International Journal of Economics and Finance , 2011, DOI: 10.5539/ijef.v4n1p110
Abstract: What is the role of news shocks in the macroeconomic fluctuations in the Japanese economy, and what is the source of the news shocks? In this paper, we estimate a structural-vector-error-correction model (SVECM) and assess the relative role of news shocks on future total factor productivity (TFP) following the methodology of Beaudry and Portier (2005). We find that anticipated technology plays a substantial role in explaining the Japanese macroeconomic movements. To answer the second question, we investigate whether the TFP process in the U.S. can be the source of the Japanese news shocks. We identify U.S. TFP shocks in both surprise and anticipated forms and capture the international technology diffusion process. We find that the U.S. TFP shocks can explain a large part of the Japanese TFP process in the long run, and contributes considerably to the Japanese macroeconomic fluctuations.
Changing C-N Interactions in the Forest Floor under Chronic N Deposition: Implications for Forest C Sequestration
Park, Ji-Hyung
Journal of Ecology and Field Biology , 2008,
Abstract: Atmospheric N deposition has far-reaching impacts on forest ecosystems, including on-site impactssuch as soil acidification, fertilization, and nutrient imbalances, and off-site environmental impacts such as nitrateleaching and nitrous oxide emission. Although chronic N deposition has been believed to lead to forest Nsaturation, recent evidence suggests that N retention capacity, particularly in the forest floor, can be surprisinglyhigh even under high N deposition. This review aims to provide an overview of N retention processes in theforest floor and the implications of changing C-N interactions for C sequestration. The fate of available N in forestsoils has been explained by the competitive balance between tree roots, soil heterotrophs, and nitrifiers. However,high rates of N retention have been observed in numerous N addition experiments without noticeableincreases in tree growth and soil respiration. Alternative hypotheses have been proposed to explain the gap betweenthe input and loss of N in N-enriched, C-limited systems, including abiotic immobilization and mycorrhizalassimilation, both of which do not require additional C sources to incorporate N in soil N pools. Different fatesof N in the forest floor have different implications for C sequestration. N-induced tree growth can enhance Caccumulation in tree biomass as observed across temperate regions. C loss from forests can amount to oroutweigh C gain in N-saturated, declining forests, while another type of ‘C-N decoupling’ can have positive orneutral effects on soil C sequestration through hampered organic matter decomposition or abiotic N immobilization,respectively.
Life History Traits and the Rate of Molecular Evolution in Galliformes (Aves)
Eo, Soo Hyung
Journal of Ecology and Field Biology , 2008,
Abstract: Rates of molecular evolution are known to vary widely among taxonomic groups. A number ofstudies, examining various taxonomic groups, have indicated that body size is negatively and clutch size ispositively correlated with the rates of nucleotide substitutions among vertebrate species. Generally, either smallerbody mass or larger clutch size is associated with shorter generation times and higher metabolic rates. However,this generality is subject to ongoing debate, and large-scale comparative studies of species below the Order levelare lacking. In this study, phylogenetically independent methods were used to test for relationships between ratesof the mitochondrial cytochrome b evolution and a range of life history traits, such as body mass and clutchsize in the Order Galliformes. This analysis included data from 67 species of Galliformes birds and 2 outgroupspecies in Anseriformes. In contrast to previous studies, taxa were limited to within-Order level, not to Classor higher. I found no evidence to support an effect of life history traits on the rate of molecular evolution withinthe Galliformes. These results suggest that such relationship may be too weak to be observed in comparisonsof closely related species or may not be a general pattern that is applicable to all nucleotide sequences or alltaxonomic groups.
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