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Search Results: 1 - 10 of 8017 matches for " DHIRAJ SHARMA "
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Does Technology Lead to Better Financial Performance? A Study of Indian Commercial Banks
Dhiraj Sharma
Managing Global Transitions , 2012,
Abstract: It has been a matter of debate whether Technology provides better financial results and improves productivity. The present paper attempts to study the inter-group comparison of financial performance of Indianbanks by classifying the banks on the basis of usage of Technology. Further,for the purpose of temporal comparison, the period for the studyhas been divided into two parts, i. e. low technology induction periodand high technology induction period. Findings of the paper show thatthe fully IT oriented banks are financially better off than the partiallyIT oriented banks. Moreover, the performance of almost all the banksunder study has tremendously improved in the high technology inductionperiod. However, for the Indian banking industry, the correlationbetween Technology induction and financial productivity is negativethough statistically insignificant and low.
TEC and Instrumental Bias Estimation of GAGAN Station Using Kalman Filter and SCORE Algorithm  [PDF]
Dhiraj Sunehra
Positioning (POS) , 2016, DOI: 10.4236/pos.2016.71004
Abstract: The standalone Global Positioning System (GPS) does not meet the higher accuracy requirements needed for approach and landing phase of an aircraft. To meet the Category-I Precision Approach (CAT-I PA) requirements of civil aviation, satellite based augmentation system (SBAS) has been planned by various countries including USA, Europe, Japan and India. The Indian SBAS is named as GPS Aided Geo Augmented Navigation (GAGAN). The GAGAN network consists of several dual frequency GPS receivers located at various airports around the Indian subcontinent. The ionospheric delay, which is a function of the total electron content (TEC), is one of the main sources of error affecting GPS/SBAS accuracy. A dual frequency GPS receiver can be used to estimate the TEC. However, line-of-sight TEC derived from dual frequency GPS data is corrupted by the instrumental biases of the GPS receiver and satellites. The estimation of receiver instrumental bias is particularly important for obtaining accurate estimates of ionospheric delay. In this paper, two prominent techniques based on Kalman filter and Self-Calibration Of pseudo Range Error (SCORE) algorithm are used for estimation of instrumental biases. The estimated instrumental bias and TEC results for the GPS Aided Geo Augmented Navigation (GAGAN) station at Hyderabad (78.47°E, 17.45°N), India are presented.
PHYLOGENETIC SELECTION GUIDED SACCHAROMYCES CEREVISIAE S288C GLUCOSE FERMENTATION MODELING
ASHISH RUNTHALA,ANKITASH TULYANI,DHIRAJ SHARMA,MAHAVEER SINGH
International Journal of Bioinformatics Research , 2011,
Abstract: Fermentation products are indigenous to many civilizations, and they have been produced by industriessince a long time. Saccharomyces cerevisiae S288C (commonly known as baker's yeast) is the strain mainly usedin the Glucose based fermentation industries. We have seen the use of same yeast strain at different places withdifferent Phenotypic Constraints. The way to improve the adaptability of considered strain for desired phenotypicconditions, using smart selection of genes through cybernetic modeling is illustrated. Phylogenetic homologues forall S. cerevisiae S288c Glucose Fermentation pathway genes were screened to search evolutionarily relatedfunctional domains in other yeast strains like Saccharomyces cerevisiae YJM789, Candida glabrata CBS138,Kluyveromyces lactis NRRL Y-1140, Ashbya gossypii ATCC10895 etc., which are adapted naturally in different setof environment. We observed that Saccharomyces cerevisiae YJM789, Candida glabrata CBS138, Ashbyagossypii ATCC10895, Kluyveromyces lactis NRRL Y-1140 possess highly conserved functional domains, whichcan be carefully selected based on usage. This study aims at designing an algorithm to select and incorporateevolutionary homologues for genes of a considered strain, which mostly show sub-optimal performance in thedesired set of experimental constraints. Such a consideration of native microenvironment and evolutionarycloseness in the selection of functional homologues of the entire genetic set can thus be significantly fruitful.
Expression analysis of boiling-stable protein (BsCyp) in response to drought, salt and osmotic treatments in drought tolerant and susceptible cultivars of Triticum aestivum
Gurmeen Rakhra,Arun Dev Sharma,Jatinder Singh,Dhiraj Vyas
Journal of Stress Physiology & Biochemistry , 2011,
Abstract: The effect of osmotic, drought and salt stresses on the induction of boiling-stable proteins were studied in C-306 (drought tolerant) and HD-2004 (drought susceptible) cultivars of Triticum aestivum. Western blotting analysis, using polyclonal antibodies raised against a 20 kDa A. thaliana cyclophilin, revealed the induction of a cross-reacting band (40 kDa, BsCyp) in cv. 306. However no substantial expression was observed in drought sensitive cv. HD-2004, indicating its role in water stress adaptation. Thermostability studies of BsCyp in cv. 306 revealed that BsCyp was stable and can be detected even after 20 min of boiling treatment under all the stresses. Based upon these observations the possible role of BsCyp in water stress tolerance is discussed.
Characterization and Modeling of Urban Water Quality in the City of Calgary, Canada  [PDF]
Dhiraj Shrestha, Jianxun He
Natural Resources (NR) , 2017, DOI: 10.4236/nr.2017.88032
Abstract: Non-point source pollution (NPS) besides point source pollution (PS) has contributed to pollutant loading into natural receiving water bodies. Due to the nature of NPS, the quantification of pollutant loading from NPS is very challenging but crucial to riverine water quality management, especially for the river reach flowing through urban areas. The water quality in the river reach of the Bow River flowing through the City of Calgary in Alberta, Canada, is affected by both PS and NPS. Thus, understanding and characterizing water quality of discharges (affected by NPS) into the river reach is necessary for better managing riverine water quality and preventing water quality degradation. In the paper, monitored event mean concentrations (EMCs) of stormwater runoff and mean concentrations of snowmelt and baseflow of seven common pollutants from sub-catchments, which are categorized into four land use types including commercial, industrial, residential and on-going development land uses, were used to investigate the linkage between land use and water quality. Statistical analysis techniques were adopted to identify differences or similarities in water quality among different flow types, different land use types, and among/between catchments of same land use. The results indicated that EMCs of many water quality parameters vary among different land use types and among/between catchments of same land use. The results also showed median EMCs of pollutants of snowmelt and baseflow are, in general, lower than those of stormwater runoff. In addition, Stormwater Management Model was employed to investigate the physical process that would affect water quality response to storm events for two typical land uses, industrial and residential land uses. The modeling results supported that wash-off of particulate matters might primarily affect water quality response of catchments between different land uses. All the results shed the light on the necessity of quantifying pollutant loading considering the characteristics of land uses.
Functional Characterization of Stromal Osteopontin in Melanoma Progression and Metastasis
Santosh Kumar, Priyanka Sharma, Dhiraj Kumar, Goutam Chakraborty, Mahadeo Gorain, Gopal C. Kundu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0069116
Abstract: Background Recent studies demonstrated that not only tumor derived- but stroma derived factors play crucial role in cancer development. Osteopontin (OPN) is a secreted non-collagenous, sialic acid rich, chemokine-like phosphoglycoprotein that facilitates cell-matrix interactions and promotes tumor progression. Elevated level of OPN has been shown in melanoma patient and predicted as a prognostic marker. Recent reports have indicated that stroma-derived OPN are involved in regulating stem cell microenvironment and pre-neoplastic cell growth. However, the function of stroma derived OPN in regulation of side population (SP) enrichment leading to melanoma growth, angiogenesis and metastasis is not well studied and yet to be the focus of intense investigation. Methodology/Principal Findings In this study, using melanoma model, in wild type and OPN knockout mice, we have demonstrated that absence of host OPN effectively curbs melanoma growth, angiogenesis and metastasis. Melanoma cells isolated from tumor of OPN wild type (OPN+/+) mice exhibited more tumorigenic feature as compared to the parental cell line or cells isolated from the tumors of OPN KO (OPN?/?) mice. Furthermore, host OPN induces VEGF, ABCG2 and ERK1/2 expression and activation in B16-WT cells. We report for the first time that stroma derived OPN regulates SP phenotype in murine melanoma cells. Moreover, loss in and gain of function studies demonstrated that stroma-derived OPN regulates SP phenotype specifically through ERK2 activation. Conclusions This study establish at least in part, the molecular mechanism underlying the role of host OPN in melanoma growth and angiogenesis, and better understanding of host OPN-tumor interaction may assist the advancement of novel therapeutic strategy for the management of malignant melanoma.
SST and ADITYA tokamak research in India
Bora, Dhiraj;,;,;
Brazilian Journal of Physics , 2002, DOI: 10.1590/S0103-97332002000100032
Abstract: steady state operation of tokamaks plays an important role in high temperature magnetically confined plasma research. steady state superconducting tokamak (sst) programme in india deals with the development of various technologies in this direction. sst-1 [1] machine has been engineered and is being fabricated at the institute for plasma research. the objectives of the machine are to study physics of plasma processes under steady state condition and develop the technologies related to steadystate operation. various sub-systems are being prototyped and developed. sst-1 is a large aspect ratio machine with a major radius of 1.1 m and a plasma minor radius of 0.2 m with elongation of 1.7 to 1.9 and triangularity of 0.5 to 0.7. it has been designed for 1000 sec operation at 3 t toroidal magnetic eld. neutral beam injection and radio frequency heating systems are being developed to heat the plasma. lower hybrid current drive system would sustain 200 ka of plasma current during 1000 sec operation. aditya tokamak [2] has been upgraded with new diagnostics and rf heating systems. thomson scattering and ece diagnostics have been operated. 200 kw ion cyclotron resonance heating (icrh) and 200 kw electron cyclotron resonance heating (ecrh) systems have been successfully commissioned. rf assisted initial breakdown experiments have been initiated with these systems.
An Improved Approach to perform Crawling and avoid Duplicate Web Pages
Dhiraj Khurana
International Journal of Computer Science and Management Studies , 2012,
Abstract: When a web search is performed it includes many duplicate web pages or the websites. It means we can get number of similar pages at different web servers. We are proposing a Web Crawling Approach to Detect and avoid Duplicate or Near Duplicate WebPages. In this proposed work we are presenting a keyword Prioritization based approach to identify the web page over the web. As such pages will beidentified it will optimize the web search.
SST and ADITYA tokamak research in India
Bora Dhiraj
Brazilian Journal of Physics , 2002,
Abstract: Steady state operation of tokamaks plays an important role in high temperature magnetically confined plasma research. Steady state Superconducting Tokamak (SST) programme in India deals with the development of various technologies in this direction. SST-1 [1] machine has been engineered and is being fabricated at the Institute for Plasma Research. The objectives of the machine are to study physics of plasma processes under steady state condition and develop the technologies related to steadystate operation. Various sub-systems are being prototyped and developed. SST-1 is a large aspect ratio machine with a major radius of 1.1 m and a plasma minor radius of 0.2 m with elongation of 1.7 to 1.9 and triangularity of 0.5 to 0.7. It has been designed for 1000 sec operation at 3 T toroidal magnetic eld. Neutral beam Injection and Radio frequency heating systems are being developed to heat the plasma. Lower hybrid Current Drive system would sustain 200 kA of plasma current during 1000 sec operation. ADITYA tokamak [2] has been upgraded with new diagnostics and RF heating systems. Thomson Scattering and ECE diagnostics have been operated. 200 kW Ion Cyclotron Resonance Heating (ICRH) and 200 kW Electron Cyclotron Resonance Heating (ECRH) systems have been successfully commissioned. RF assisted initial breakdown experiments have been initiated with these systems.
Unraveling the Design Principle for Motif Organization in Signaling Networks
Samrat Chatterjee, Dhiraj Kumar
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0028606
Abstract: Cellular signaling networks display complex architecture. Defining the design principle of this architecture is crucial for our understanding of various biological processes. Using a mathematical model for three-node feed-forward loops, we identify that the organization of motifs in specific manner within the network serves as an important regulator of signal processing. Further, incorporating a systemic stochastic perturbation to the model we could propose a possible design principle, for higher-order organization of motifs into larger networks in order to achieve specific biological output. The design principle was then verified in a large, complex human cancer signaling network. Further analysis permitted us to classify signaling nodes of the network into robust and vulnerable nodes as a result of higher order motif organization. We show that distribution of these nodes within the network at strategic locations then provides for the range of features displayed by the signaling network.
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