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Search Results: 1 - 10 of 17 matches for " DEVERSHI MOURYA "
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International Journal of Engineering Science and Technology , 2012,
Abstract: A combustion model is developed for the diesel engine combustion, when biodiesel and diesel are used as blended fuel. The model is applied to simulate the diesel engine combustion emissions, when different blends of jatropha biodiesel and diesel are used as fuel for diesel engine. Simulation results the variation of the mole fractions of various combustion emission products with the equivalence ratio, when different blends of jatropha biodiesel and diesel are used as fuel. The results show that the present combustionmodel gives reliable performance for the predictions of combustion emissions, as well as computational efficiency.
Quality by Design: Impact of Product Variables and Their Interaction on the Particle Size in Lyophilization of Sodium Fluoride  [PDF]
V. K. Mourya, Yogesh Choudhari, Mangeshkumar Padame
Soft Nanoscience Letters (SNL) , 2016, DOI: 10.4236/snl.2016.61001
Abstract: The aim of present study was to use QbD approaches to evaluate the effect of independent product variables and their interaction on particle size of sodium fluoride and then obtain the optimized experimental condition for predefined particle size of sodium fluoride. The sodium fluoride is mainly used in dental preparation for delivering the fluoride ion to the tooth enamel for that nano-particle size is required. Nowadays the milling process is used to reduce the particle size. But that process has some limitations due to crystalline nature of sodium fluoride; for overcoming those limitations, lyophilization method is used. A 43 level full factorial design was used to study the significant influence of process and product variables i.e. 1) Concentration of sodium fluoride, 2) Concentration of PVP, 3) Sample volume, 4) Drying surface, on particle size of sodium fluoride. The experimental design result shows that independent product variables significantly modify the structure and improve particle size reduction of sodium fluoride.
Abhay Kumar Mourya et al.
International Journal of Pharmaceutical Sciences and Research , 2012,
Abstract: The present research work has been carried out for an optimized formulation of co-processed directly compressible vehicles in the preparation of the Acetaminophen mouth fast dissolving tablets (MFDTs). Acetaminophen was chosen due to its poor compression properties. Di-calcium Phosphate(DCP) was incorporated in the neutralized aqueous starch dispersion to prepare co-processed excipient. Co-processed direct compressible DCP and Starch used as co-processed excipient were taken in good formulation ratio such as (25:75) and Cross Povidone used as superdisintegrant. The effects of other superdisintegrants were studied in the best formulation F5. Formulation F5 was found to be optimum compressibility characteristics hardness 3.62±0.40 to 4.68±0.31 kg/cm2 with fast disintegration (10 sec) compare to other formulations.
Managing Congestion Control in Mobile AD-HOC Network Using Mobile Agents
Ashish Kumar Mourya,Niraj Singhal
Computer Science , 2014,
Abstract: In mobile adhoc networks, congestion occurs with limited resources. The standard TCP congestion control mechanism is not able to handle the special properties of a shared wireless channel. TCP congestion control works very well on the Internet. But mobile adhoc networks exhibit some unique properties that greatly affect the design of appropriate protocols and protocol stacks in general, and of congestion control mechanism in particular. As it turned out, the vastly differing environment in a mobile adhoc network is highly problematic for standard TCP. Many approaches have been proposed to overcome these difficulties. Mobile agent based congestion control Technique is proposed to avoid congestion in adhoc network. When mobile agent travels through the network, it can select a less-loaded neighbor node as its next hop and update the routing table according to the node congestion status. With the aid of mobile agents, the nodes can get the dynamic network topology in time. In this paper, a mobile agent based congestion control mechanism is presented.
An Activity guided Isolation and Evaluation of various Solvent Extracts of the Leaves of Anjan Grass
Premlata Singariya*, Padma Kumar,Krishan Kumar Mourya
Hygeia : Journal for Drugs and Medicines , 2012,
Abstract: Plan: The present study was undertaken to identify the possible bioactive components and antimicrobial activity in various polar solvents from the leaves of Anjan grass (Cenchrus ciliaris) (Poaceae).Materials and methods: New compounds were identified by GC-MS analysis. Antimicrobial activity was evaluated against Proteus mirabilis, Klebsiella pneumoniae, Agrobacterium tumefaciens and Aspergillus niger using disk diffusion method followed by MIC by broth dilution method.Outcome: Various aromatic, steroids, fatty acids and esters from C. ciliaris were identified. The prevailing compounds in the ethyl acetate extract of C. ciliaris were 4,22-stigmastadiene-3-one (2.41%), cyclopentacycloheptene (azulene) (1.81%), ergost-5-en-3-ol (3β, 24R)- (campesterol) (1.63%) and myristic acid, isopropyl ester (0.17%). The highest antimicrobial activity was exhibited by the glacial acetic acid extract against P. mirabilis. The presence of various bioactive compounds justifies the use of this plant for various ailments by traditional practitioners. However, isolation of individual photochemical constituents and subjecting it to biological activity will definitely give fruitful results.
Molecular characterization of Umbre virus (Bunyaviridae)
Pragya D Yadav, Akhilesh C Mishra, Devendra T Mourya
Virology Journal , 2008, DOI: 10.1186/1743-422x-5-115
Abstract: The viruses of Bunyaviridae family are spherical particles, range 80 to 120 nm in diameter and share a common genetic organization of three predominantly negative stranded RNA segments (S, M and L). Based on antigenic, genetic and ecological relatedness, the Bunyaviruses are divided into five genera. The genus Orthobunyavirus includes approximately 60 viruses, which are known to cause disease in humans (Elliot, 1996). Virological surveillance of these viruses depends primarily on detecting the viruses in arthropod vector populations in nature. Although, serological test like immunoassays are available for antigen detection for a few viruses, cross-reaction in closely related viruses cannot be ignored (Artsob et. al., 1984; Hildreth et. al., 1982).Umbre virus (UMB) [strain G-1424] was first isolated from Culex bitaeniorhynchus mosquitoes, collected in 1955 at Umbre, Kolaba district, Maharashtra State, India. The virus has been registered in the International Arbovirus Catalogue No. 43 (Dandwate et. al., 1969). During further field investigations, seven more strains of virus were isolated from Cx. vishnui mosquitoes. Recent reports on Bunyaviruses via. Ganjam virus isolation from Maharashtra (Joshi et. al., 2004) and antibody detection of Hantan virus in India (Chandi et. al., 2005), has provided evidences that Bunyaviruses are circulating in this country but their involvement in causing human and animal disease are not known yet. In the Gene Bank, only one sequence of Turlock serogroup i.e. N gene of M'poke virus is available.UMB viruses used in this study are listed in (Table 1) along with their geographical origin, host source and year of isolation. The available eight strains of this virus was procured from the virus registry of National Institute of Virology, Pune and propagated in VeroE-6 cells. Cytopathic effect (CPE) was observed during 4th – 6th post infection day. Infected cells were harvested, centrifuged and supernatant was used for molecular characterizat
Asian Journal of Pharmacy and Life Science , 2011,
Abstract: Salvia officinalis L. is a perennial woody shrub; mainly dried leaves used as raw material in medicine,perfumery and food industry. The aim of this study was to investigate diuretic effects of leaf extract of Salviaofficinalis L. in normal rats. Methanolic extract of Salvia officinalis L. leaves were administered toexperimental rats orally at doses of 50 and 100 mg/kg p.o., Hydrochlorothiazide (10 mg/kg) was used aspositive control in study. The diuretic effect of the extract was evaluated by measuring urine volume &excretion of sodium-potassium content. Urine volume was significantly increased by methanolic extract incomparison to control group. While the excretion of sodium was also increased by extract (100mg/kg). Themethanolic extract had the additional advantage of a potassium-conserving effect. We can conclude thatmethanolic extract of Salvia officinalis L. produced notable diuretic effect which appeared to becomparable to that produced by the reference diuretic HCTZ (Hydrochlorothiazide). The present studyprovides a quantitative basis for explaining the folkloric use of Salvia officinalis L. as a diuretic agent.
Comparative Pharmacological Study of Fruits and Flowers Extract of Withania somnifera
Dr. Premlata Singariya,Prof. Padma Kumar,Dr. Krishan Kumar Mourya
International Journal of Pharmaceutical and Phytopharmacological Research , 2012,
Abstract: The in vitro antibacterial activity of Methanolic extracts of Withania somnifera (Solanaceae), was evaluated against seven Gram-negative bacteria, two Gram-positive bacteria and three fungi, using disk diffusion method followed by determination of minimum inhibitory concentrations by broth dilution method, against sensitive bacteria and fungi. Most of the extracts, at higher concentrations showed varying degrees of inhibitory activity against bacteria and fungi. The highest bio-activity was exhibited by the calyx extract against Pseudomonas aeruginosa. Staphylococcus aureus, Bacillus subtilis and Agerobacterium tumefaciens were the most sensitive pathogens after P. aeruginosa witch show maximum antimicrobial effects. Gentamycin and Ketoconazole, the standard antibiotics used were effective against the bacteria and fungi respectively.
Singariya P.,Kumar P.,Mourya K.K.
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: Crude extracts of different parts (root, stem, leaf and seed) of Cenchrus ciliaris (CAZRI-358) and (root, stem, leaf and flower) of Withania somnifera (RUBL-20668) and were successively extracted with polar to non polar solvents (water, chloroform and benzene) using soxhlet assembly. The extracts were then screened for their antimicrobial activity in-vitro against one gram positive bacteria (Bacillus subtilis), two gram negative bacteria (Pseudomonas aeruginosa and Enterobactor aerogens) and one fungus (Aspergillus flavus) by disc diffusion assay. Serial dilution method was used to determine minimum inhibitory concentration (MIC) and minimum bactericidal/fungicidal concentration (MBC/MFC). Chloroform extract of leaves of both the plants showed highest activity, by W. somnifera (IZ-20.83±0.21 mm, AI- 1.389) and (IZ-20.67±0.24 mm, AI- 1.148) by C. ciliaris against B. subtilis and P. aeruginosa respectively.
Xenodiagnosis: use of mosquitoes for the diagnosis of arboviral infections
D.T. Mourya, M.D. Gokhale , R. Kumar
Journal of Vector Borne Diseases , 2007,
Abstract: The arboviruses have a worldwide distribution and, mosquitoes and ticks contribute principally intheir transmission. In the last two decades, arboviral diseases have been recognised due to theirresurgence and spread in newer geographic areas. Surveys to determine the prevalence of arbovirusesin any region largely depend on the isolation attempts from the arthropods along with the serosurveys.Xenodiagnosis means use of insects for the diagnosis of infectious diseases affecting humanbeing. The present communication discusses the application of mosquitoes for propagation and assaysof arboviruses, the technique of mosquito inoculation and importance of xenodiagnosis.
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