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Search Results: 1 - 10 of 191745 matches for " D. Sudha "
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Effect of different concentrations of metal ions on alpha amylase production by Bacillus amyloliquefaciens
Sudha
Research in Biotechnology , 2012,
Abstract: Bacillus amyloliquefaciens is obtained from soil which produces extracellular alphaamylase enzyme. The present study is concerned with effect of metal ions on alpha amylaseproduction. Metal ions are Ca2+, Cu2+, Mg2+, Fe2+ and Mn2+ at different concentrations 2g/l,5g/l and 7g/l. Supplementations of salts of certain ions provide good growth ofmicroorganism and production of alpha amylase. Ca2+and Mg2+exhibit positive influence onalpha-amylase production. Our results show that the amylase production is higher in thepresence of Ca2+ (0.439) IU/ml/min at 7g/l concentration in comparison of other metal ions.The enzyme activity of Mg2+(0.321) IU/ml/min at 2g/l concentration. The study focuses onsupplementation of metal ions increase the production of amylase.
An Effective and Customized Itinerary Planning System Using Association Rule Mining Technique with Personalized Points of Interest  [PDF]
M. Krishnamurthy, D. Sudha, Y. Narasimha Rao, R. Baskaran, A. Kannan
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.77096
Abstract: Mining the data from the huge collection that are present in the database and uncovering the relationships between the item set are one of the key aspects of data mining technologies. Itinerary planning system with personalization in selecting the places to the users is one of the demanding features in most of the travel plan. In this work, the system is designed in such a way to provide the customized journey plan to the users and also the effective one to the back pack travelers. Here the Points of Interests are the places to visit in each destination for the number of days chosen by the travelers. In this system, the users are allowed to specify the desired POIs to visit for the selected destination and can make their customized travel plan effectively. This proposed system is designed to choose the customized places to visit and to plan travel for K-day itineraries. The most visited itineraries are saved and updated in the database. Association rules are used to find out the frequent places visited in each destination and to provide the reputed places to the users to plan the journey. Here the Weka tool is used to evaluate the performance of the algorithm and the rules that are generated for the given travel dataset. Data set is designed by considering several attributes that can take part during travel such as source, destination, travel cost, budget, etc. Statistical analysis is done to evaluate the performance of the proposed system and the list of features that are present in the system. During the analysis part, registered users, number of logins, frequent visits, and attributes are analyzed. Thus the system can be redefined further with the help of this statistical analysis. It is mostly used at the organization end to evaluate their performance and improve the features. Report is generated once the user has chosen their customized places to visit and all detailed description of journey is presented to the user. Report could be saved at the user end and they can use it for the future reference. Thus the goal of the system is to provide the customized travel with personalization in choosing POIs and to find the frequent places visited with desired amenities.
Awareness, attitudes, and beliefs of the general public towards HIV/Aids in Hyderabad, a capital city from South India
Sudha R,Vijay D,Lakshmi V
Indian Journal of Medical Sciences , 2005,
Abstract: CONTEXT: Information is the first step in human immunodeficiency virus (HIV) prevention. Ignorance about the disease and how the virus is transmitted can generate fear and prejudice towards those who are infected. AIM: To assess the awareness, attitudes, and beliefs of the general public toward HIV/AIDS in Hyderabad, the capital city of Andhra Pradesh. SETTING AND DESIGN: A cross-sectional study conducted for a period of 2 months in 2004 on 800 individuals living in Hyderabad. MATERIALS AND METHODS: A survey was conducted with a questionnaire titled ′General Population Behavioral Surveillance Survey.′ The survey used a 5-part, 65-item questionnaire eliciting information about the knowledge of HIV (10 items), modes of transmission (20 items), ways of prevention (10 items), society′s attitude toward HIV (15 items), and finally evaluation of Government′s measures (10 items). RESULTS: Approximately 80.63% (645/800) of the study population were sketchily aware of HIV/AIDS, but had incorrect perceptions about the mode of transmission or prevention. Despite the vigorous outreach programmes, which the government and other organizations had carried out in the city, many people had several misconceptions about HIV or about people living with HIV/AIDS. CONCLUSION: As it was observed that awareness was more among the literates, the Government and Health educators should provide tailor-made education programmes for those at the lower education levels.
EFFECT OF HEAVY METALS COPPER AND CADMIUM EXPOSURE ON THE ANTIOXIDANT PROPERTIES OF THE PLANT BRASSICA JUNCEA
T. E. Haribabu,d P. N. Sudha
International Journal of Chemical Sciences and Research , 2011,
Abstract: The Contamination of the environment by toxic metals poses a threat for “Man and biosphere”, reducing agricultural productivity and damaging the health of the ecosystem. Phytoextraction has emerged as a novel approach to clean up metal-polluted soils in which plants are used to transfer toxic metals from soils to shoots.During the accumulation of heavy metal, the antioxidant defence system helps the plant to protect itself from the damage caused by heavy metals. Antioxidants are substances that protect itself from damage caused by oxidation. In the present work the plant Brassica juncea was exposed to the sublethal and half of sublethal concentration of copper and cadmium spiked soils and the antioxidant factors were investigated. The results showed that biochemical factors, vitamins and minerals, antioxidant activity and catalase values were decreased and proline, SOD and reduced glutathione values were increased compared to garden (control) soil.
High Frequency Charging Techniques—Grid Connected Power Generation Using Switched Reluctance Generator  [PDF]
S. Sridharan, S. Sudha
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.714352
Abstract: Power generation becomes the need of developed, developing and under developed countries to meet their increasing power requirements. When affordability increases their requirement of power increases, this happens when increased per capita consumption. The existing power scenario states that highest power is produced using firing of coals called thermal energy. A high efficiency Switched Reluctance Generator (SRG) based high frequency switching scheme to enhance the output for grid connectivity is designed, fabricated and evaluated. This proposed method generates the output for the low wind speed. It provides output at low speed because of multi-level DC-DC converter and storage system. It is an efficient solution for low wind power generation. The real time readings and results are discussed.
Biomechanical Thresholds Regulate Inflammation through the NF-κB Pathway: Experiments and Modeling
Jin Nam, Baltazar D. Aguda, Bjoern Rath, Sudha Agarwal
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0005262
Abstract: Background During normal physical activities cartilage experiences dynamic compressive forces that are essential to maintain cartilage integrity. However, at non-physiologic levels these signals can induce inflammation and initiate cartilage destruction. Here, by examining the pro-inflammatory signaling networks, we developed a mathematical model to show the magnitude-dependent regulation of chondrocytic responses by compressive forces. Methodology/Principal Findings Chondrocytic cells grown in 3-D scaffolds were subjected to various magnitudes of dynamic compressive strain (DCS), and the regulation of pro-inflammatory gene expression via activation of nuclear factor-kappa B (NF-κB) signaling cascade examined. Experimental evidences provide the existence of a threshold in the magnitude of DCS that regulates the mRNA expression of nitric oxide synthase (NOS2), an inducible pro-inflammatory enzyme. Interestingly, below this threshold, DCS inhibits the interleukin-1β (IL-1β)-induced pro-inflammatory gene expression, with the degree of suppression depending on the magnitude of DCS. This suppression of NOS2 by DCS correlates with the attenuation of the NF-κB signaling pathway as measured by IL-1β-induced phosphorylation of the inhibitor of kappa B (IκB)-α, degradation of IκB-α and IκB-β, and subsequent nuclear translocation of NF-κB p65. A mathematical model developed to understand the complex dynamics of the system predicts two thresholds in the magnitudes of DCS, one for the inhibition of IL-1β-induced expression of NOS2 by DCS at low magnitudes, and second for the DCS-induced expression of NOS2 at higher magnitudes. Conclusions/Significance Experimental and computational results indicate that biomechanical signals suppress and induce inflammation at critical thresholds through activation/suppression of the NF-κB signaling pathway. These thresholds arise due to the bistable behavior of the networks originating from the positive feedback loop between NF-κB and its target genes. These findings lay initial groundwork for the identification of the thresholds in physical activities that can differentiate its favorable actions from its unfavorable consequences on joints.
3-Benzyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline
K. Chinnakali,D. Sudha,M. Jayagobi,R. Raghunathan
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536809044547
Abstract: In the title compound, C31H30N2O2S, the pyrrolidine ring adopts a twist conformation while the tetrahydropyridine ring is in a half-chair conformation. The two rings are trans-fused. The pyridine-bound phenyl ring forms dihedral angles of 17.7 (1) and 48.1 (1)°, respectively, with the tosyl and benzyl phenyl rings. The molecular structure is stabilized by an N—H...π interaction involving the benzyl phenyl ring. In the crystal structure, molecules translated by one unit along the a axis are linked into chains by C—H...π interactions involving the benzene ring of the tosyl group.
cis-1-Ethyl-4,4,6,8-tetramethyl-2-tosyl-2,3,3a,4,6,7,8,9-octahydro-1H-pyrrolo[3′,4′:3,4]pyrano[6,5-d]pyrimidine-7,9-dione
K. Chinnakali,D. Sudha,M. Jayagobi,R. Raghunathan
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536809026361
Abstract: In the title compound, C22H29N3O5S, the pyrrolidine ring is cis-fused to the dihydropyran ring. The pyrrolidine and dihydropyran rings adopt twist and half-chair conformations, respectively. The molecule is in a folded conformation; the sulfonyl-bound benzene ring lies over the pyrimidinedione ring, with a weak π–π interaction [centroid–centroid distance = 3.6147 (4) ]. A weak intramolecular C—H...O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked into a three-dimensional network by C—H...O hydrogen bonds.
3-Benzyl-7-chloro-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline
K. Chinnakali,D. Sudha,M. Jayagobi,R. Raghunathan
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536809045267
Abstract: In the title compound, C31H29ClN2O2S, the pyrrolidine ring adopts an envelope conformation with the methine C atom adjacent to the NH group as the flap atom. The tetrahydropyridine ring has a half-chair conformation. The two rings are trans-fused. The chlorobenzene ring and the adjacent phenyl ring form a dihedral angle of 77.9 (1)°. The benzyl phenyl and the tosyl phenyl rings are oriented at a dihedral angle of 88.0 (1)°. In the crystal, molecules are linked into chains along the a axis by N—H...Cl and C—H...Cl hydrogen bonds and the adjacent chains are cross-linked via C—H...π interactions.
1-Benzyl-6,8-dimethyl-4-phenyl-2-tosyl-1,2,3,3a,4,6,7,8,9,9b-decahydropyrrolo[3,4-c]pyrano[6,5-d]pyrimidine-7,9-dione
K. Chinnakali,D. Sudha,M. Jayagobi,R. Raghunathan
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536809044341
Abstract: The molecule of the title compound, C31H31N3O5S, adopts a folded conformation, with the sulfonyl-bound phenyl ring lying over the pyrimidine ring [dihedral angle = 12.04 (6)° and centroid–centroid separation = 3.6986 (8) ]. The pyrrolidine ring adopts a twist conformation, the dihydropyran ring is in a half-chair conformation and the two rings are cis-fused. The tosyl group is attached to the pyrrolidine ring in an equatorial position while the benzyl group is axially attached. The molecular structure is stabilized by weak C—H...O hydrogen bonds and C—H...π interactions. In the crystal, pairs of molecules related by inversion symmetry are linked by C—H...O hydrogen bonds, forming chains propagating along the c axis which are cross-linked into a three-dimensional framework by further C—H...O links.
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