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Search Results: 1 - 10 of 191458 matches for " D. Muralidharan "
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Cytoprotective Effect of Morinda tinctoria Roxb. against Surgical and Chemical Factor Induced Gastric and Duodenal Ulcers in Rats
D. Sivaraman,P. Muralidharan
Ulcers , 2011, DOI: 10.1155/2011/142719
Abstract: The present paper relates to the pharmacological validation of the antiulcer efficacy of ethanol leaf extract of Morinda tinctoria Roxb. (EEMT) against aspirin pyloric ligation-induced gastric ulcer model and cysteamine-induced duodenal ulcer in Wistar rats. Oral administration of EEMT at a dose of 200 and 400 mg/kg significantly prevented the occurrence of aspirin pyloric ligation and cysteamine-induced gastric and duodenal ulceration. The volume and acidity of gastric juice in pyloric ligated rats were significantly (<0.01) reduced by EEMT. There was a significant decrease in the number of ulcers, and its severity in both the models proved the ulcer protective activity of EEMT. Administration of extract at both dose levels has shown a significant increase in potassium and sodium ion concentration in the gastric juice of pylorus ligation group. On the basis of these observations, we concluded that EEMT possessing antiulcer activity may be due to the modulation of defensive factors by improvement in gastric cytoprotection.
An Innovative Test Data Compression Method Using Scan Chain Compaction
S. Sowmiyaa,D. Muralidharan
Research Journal of Applied Sciences, Engineering and Technology , 2012,
Abstract: Test data compression method is a key issue for reducing test data volume and test application time. Various techniques have been developed with great success on dealing with data compression. The previous schemes of compression techniques have been developed to reduce test data volume but the application time is not sufficiently reduced. Additional fault simulation and test generation are necessary to advice high fault coverage. The proposed Odd-Even Scan Network (OESN) provides the high compression ratio and the fast testing time. The compatible scan cell group is planned to implement and it will be integrated with the existing scan chain compaction. The experimental results on ISCAS-89 show that the proposed approach achieves high compression ratio.
Performance Analysis of NoC Architectures
Anitha G,Muralidharan D,Muthaiah R
International Journal of Engineering and Technology , 2013,
Abstract: Network-on-chip (NoC) architecture grants the communication frame work for SoC design .The Performance dominating factors of NoC are architecture, node’s size, and the routing algorithm. Various routing algorithms are proposed for the router design in Network on chip(NoC).According to the requirements of NoC application, analysis and simulations for various routing algorithms, such as Crouting,ADBR and adaptive congestion aware routing algorithm are considered for this work. The simulation results shows that Congestion aware adaptive routing algorithm has better performance than others. Here, the new adaptive routing algorithm by merging the features of ADBR and adaptive congestion aware routing algorithm has been discussed.
Ameliorating Effect of Ethanol Leaf Extract of Ficus hispida Linn. on Amyloid beta Aβ (25-35) Induced Cognitive Deficits and Oxidative Stress in Alzheimer’s Mice
D. Sivaraman,P. Muralidharan,P. Panneerselvam
International Journal of Pharmacology , 2012,
Abstract: Alzheimer’s disease is a primary degenerative disease of the central nervous system. The progression of Alzheimer’s disease will ultimately lead to dementia, behavioral and cognitive impairments. Alzheimer’s is the commonest cause of dementia, a group of progressive condition which involves especially short-term memory loss, poor concentration, poor sense of time and space, difficulty in finding words or understanding other people, difficulty in perceiving and interpreting surroundings, mood changes and emotional upsets. The present study was designed to determine the ameliorating effect of ethanolic leaf extract of Ficus hispida Linn. (EEFH) on (amyloid beta) Aβ 25-35-induced cognitive deficits and oxidative stress in mice. Animals were treated with EEFH for periods of 4 weeks dose-dependently (200 and 400 mg kg-1) then received a single intracerebroventricular (i.c.v.) injection of Aβ 25-35 (10 μg mouse-1). Behavioral changes in the mice were evaluated using passive avoidance, Y-maze, Hole board and water-maze tests. Anti-oxidant enzymes and neuro-transmitter levels were also been estimated. EEFH at the dose of 400 mg kg-1 significantly ameliorated the cognitive and memory deficits caused by i.c.v. injection of Aβ 25-35. EEFH attenuated the Aβ-induced increase in brain levels of thiobarbituric acid reactive substances. There was an increase in glutathione peroxidase, glutathione reductase and super oxide dismutase activity in EEFH treated groups. The acetyl cholinesterase activity in the brain was lower in EEFH supplemented groups than the Aβ-injected group. EEFH treated group showed a significant alteration in behavior when compare to negative control in Y maze, Plus-maze and also in water maze tests. These findings suggest EEFH exerts a protective effect against cognitive deficits induced by Aβ 25-35 accumulation in Alzheimer’s disease, because of its potential antioxidant property.
Exploring Packaging Strategies of Nano-embedded Thermoelectric Generators
Aniket Singha,Subhendra D. Mahanti,Bhaskaran Muralidharan
Physics , 2015, DOI: 10.1063/1.4933125
Abstract: Embedding nanostructures within a bulk matrix is an important practical approach towards the electronic engineering of high performance thermoelectric systems. For power generation applications, it ideally combines the efficiency benefit offered by low dimensional systems along with the high power output advantage offered by bulk systems. In this work, we uncover a few crucial details about how to embed nanowires and nanoflakes in a bulk matrix so that an overall advantage over pure bulk may be achieved. First and foremost, we point out that a performance degradation with respect to bulk is inevitable as the nanostructure transitions to being multi moded. It is then shown that a nano embedded system of suitable cross-section offers a power density advantage over a wide range of efficiencies at higher packing fractions, and this range gradually narrows down to the high efficiency regime, as the packing fraction is reduced. Finally, we introduce a metric - \emph{the advantage factor}, to elucidate quantitatively, the enhancement in the power density offered via nano-embedding at a given efficiency. In the end, we explore the maximum effective width of nano-embedding which serves as a reference in designing generators in the efficiency range of interest.
Anbu chozhan.P,D.Muralidharan,R.Muthaiah
International Journal of Engineering and Technology , 2013,
Abstract: Network on chip is a new paradigm for on chip design that is able to sustain the communication provisions for the SoC with the desired performance. NOC applies networking methodology concepts to system on chip data transfer and it gives noticeable elevation over conventionalbus based communication. NOC router is the backbone of on chip communication which directs the flow of data. In NOC router the arbiter is used during number of inputs request for the similar out port. Arbiter generates the grant based on the priority and previous granted input. For NOC router we have design the efficient round robin arbiter and analyse the power and area. In this paper on chip router is designed with a buffering technique of FWFT based asynchronous FIFO which improves timing and reduce power consumption. The proposed design of router is simulated and synthesized in Xilinx ISE 13.2 and the source code is written in Verilog. Cadence soc encounter of technology ami035 is used to generate layout of router and RTL compiler is used to compute area, power and timing.
Countermeasures Against DPA Attacks on FPGA Implementation of AES
G. Dinesh Babu,N. Nalla Anandakumar,D. Muralidharan
Journal of Artificial Intelligence , 2012,
Abstract: Even a highly secured algorithm that proves to be mathematically secured has a possibility to leak secret information, like key, thus stored while implementing them in hardware platform. This study focuses on the necessity to prevent such leakage by making some changes in the algorithm in such a way that the functionality of the algorithm is unaltered thereby assuring the possibility of attacks are greatly reduced. This study discusses the Field Programmable Gate Array (FPGA) implementation of the Advanced Encryption Standard (AES) with countermeasures against Differential Power Analysis (DPA) attacks. The study proposes two different countermeasure methods: register swapping and random recharging. As a result, it shows that these countermeasures increase the complexity of attack.
Rectification by charging -- the physics of contact-induced current asymmetry in molecular conductors
O. D. Miller,B. Muralidharan,N. Kapur,A. W. Ghosh
Physics , 2007, DOI: 10.1103/PhysRevB.77.125427
Abstract: We outline the qualitatively different physics behind charging-induced current asymmetries in molecular conductors operating in the weakly interacting self-consistent field (SCF) and the strongly interacting Coulomb Blockade (CB) regimes. A conductance asymmetry arises in SCF because of the unequal mean-field potentials that shift a closed-shell conducting level differently for positive and negative bias. A very different current asymmetry arises for CB due to the unequal number of open-shell excitation channels at opposite bias voltages. The CB regime, dominated by single charge effects, typically requires a computationally demanding many-electron or Fock space description. However, our analysis of molecular Coulomb Blockade measurements reveals that many novel signatures can be explained using a {{simpler}} orthodox model that involves an incoherent sum of Fock space excitations and {\it{hence treats the molecule as a metallic dot or an island}}. This also reduces the complexity of the Fock space description by just including various charge configurations only, thus partially underscoring the importance of electronic structure, while retaining the essence of the single charge nature of the transport process. We finally point out, however, that the inclusion of electronic structure and hence well-resolved Fock space excitations is crucial in some notable examples.
Service Quality of Mobile Banking Services in ICICI Bank Limited  [PDF]
R. Ayswarya, D. Sarala, P. Muralidharan, M. Ilankadhir
Journal of Service Science and Management (JSSM) , 2019, DOI: 10.4236/jssm.2019.125045
Abstract: Purpose: Mobile banking is the latest and most innovative service offered by Banks. The purpose of the study is to investigate the determinants of service quality of mobile banking services in ICICI. Methodology: This study was conducted by using empirical research and Cluster cum Simple random sampling method has been adopted for a sample size of 100 respondents using mobile banking services in ICICI bank Limited. Findings: 35 percent of the respondents are using the SMS mode of mobile banking services. The dimensions of service quality factors of mobile banking services maintained by ICICI Bank Ltd are Convenience, Responsiveness, Security, Accessibility, Assurance, Knowing the customer and efficiency mobile banking services. The factors that satisfy the customers’ level towards mobile banking services offered by ICICI Bank Ltd. are banking activities, banking products and other services. The reasons for using mobile banking services are Convenient services, Time-saving and quick service. Originality/Values: This paper shows that the mobile banking service quality dimensions are an important factor to satisfy the customers. The outcomes of this study enhance the knowledge on the performance of ICICI bank as well as customer satisfaction, which are invaluable to all the bank managers and industry players in improving their services.
Simple Estimation of Bosentan in Tablet Formulation by RP-HPLC  [PDF]
Selvadurai Muralidharan, Jaya Raja Kumar
American Journal of Analytical Chemistry (AJAC) , 2012, DOI: 10.4236/ajac.2012.311095
Abstract: A simple, precise, and accurate method is developed and validated for the analysis of Bosentan tablet formulation. The method has shown adequate separation of the ingredients from Tablets. Separation was achieved on a C18 column using a mobile phase consisting of acetonitrile: 10 Mm ammonium acetate (pH 4.5) buffer (70:30, v/v) at a flow rate of 1.0 ml/min and UV detection at 265 nm. This new method is validated as per the ICH, which includes accuracy, precision, selectivity, linearity and range, robustness and ruggedness. The current method demonstrates good linearity over the range of 5 - 70 ng/ml of bosentan with r2 of 0.999. The average recovery of the method is 98.6%. The degree of reproducibility of the results obtained as an outcome of small deliberate variations in the method parameters and by changing analytical operator has proven that this method is robust and rugged.
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