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Search Results: 1 - 10 of 379045 matches for " Díaz Martín Ruth Marina "
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Variación espacio-temporal de la lluvia de semillas en pastizales abandonados de alta monta a tropical (Reserva Forestal Municipal de Cogua)
Díaz Martín Ruth Marina,Vargas Ríos Orlando
Acta Biológica Colombiana , 2004,
Abstract: Se evaluó la variación espacio-temporal de la lluvia de semillas en dos pastizales con diferentes edades de abandono pertenecientes a la Reserva Forestal Municipal de Cogua (Cundinamarca). Se seleccionó un pastizal con 11 a os de abandono ubicado a 3.350 msnm (pastizal B) y un pastizal con tres a os de abandono ubicado a 3.300 msnm (pastizal A). La fase de campo se realizó desde el 18 de enero hasta el seis de octubre de 2003, período que incluye la época seca y la época de lluvias. La lluvia de semillas del pastizal B presentó valores de abundancia, riqueza y diversidad más altos. En este pastizal cayeron casi el doble del número de semillas que las encontradas en el pastizal A (7.162 semillas frente a 3.946 semillas). En cuanto a riqueza, en el pastizal B se encontraron 74 especies, mientras que en el pastizal A se encontraron 56. De estas, 46 son comunes a los dos pastizales, incluyendo las más abundantes para cada pastizal, de modo que la lluvia de semillas en las dos zonas es semejante en composición, diferenciándose por la importancia de las especies al interior de cada una. En el pastizal A las especies dominantes fueron principalmente especies herbáceas, la mayoría de ellas exóticas o cosmopolitas. En este pastizal Geranium sibbaldioides, una herbácea formadora de cojines, fue la especie dominante en la lluvia de semillas, con una abundancia de 2.725 semillas equivalente al 69% del total. Esta especie es característica de procesos de regeneración del páramo luego de cultivos. En el pastizal B, tres especies dominan la lluvia de semillas: Diplostephium aff alveolatum (1.546 semillas), Pentacalia nitida (1.539 semillas) y Cortaderia sp. (783 semillas), las cuales representan el 54% del total. La única especie característica del bosque altoandino encontrada en la lluvia de semillas de estos pastizales fue Weinmannia tomentosa. En el pastizal A el síndrome de dispersión dominante en abundancia fue la autocoria, el síndrome de dispersión de G. sibbaldioides. Le sigue en importancia la anemocoria. En cuanto a riqueza, es la anemocoria la especie dominante. Para el pastizal B, el síndrome de dispersión dominante tanto en abundancia como en riqueza fue la anemocoria. Se encontraron además especies con síndrome de dispersión barócoro, mixto, y zoócoro en los dos pastizales. En cuanto a formas de vida, en el pastizal A dominaron las formas herbáceas como Rumex acetosella, Hypochaeris radicata y Carex sp1; mientras que en el pastizal B dominaron las formas le osas, arbustos de subpáramo como P. nitida, P ledifolia y Baccharis prunifolia. Igualmente se enco
Correlación entre los niveles de glutatión peroxidasa, un marcador de estrés oxidativo, y la presentación clínica del dengue Association between glutathione peroxidase levels and clinical manifestations of dengue
Elsa Marina Rojas,Fredi Alexander Díaz-Quijano,Carolina Coronel-Ruiz,Ruth Aralf Martínez-Vega
Revista médica de Chile , 2007,
Abstract: Background: Glutathione peroxidase (GP) can be used as a marker of oxidative stress in infectious diseases. Aim: To evaluate the association between the levels of glutathione peroxidase (GP) and the manifestations and complications of dengue. Patients and Methods: Between April 2003 and December 2004, 161 patients with dengue were prospectively evaluated. In the first evaluation, within 48 and 96 hours of disease onset, a plasma sample was obtained to measure the GP levels. The association between GP levels, clinical manifestations and complications was evaluated during the follow up. Results: Mean GP values were 1198 U/L (95% confidence interval 1089-1306). Values greater than 1200 U/L were associated with headache, arthralgias and increased heart rate. There was a negative association between GP levels and serum triglycerides. During follow up, patients with GP >1200 U/L had a higher frequency of spontaneous hemorrhages. In a logistic regression analysis arthralgias, fever and increased heart rate, were independently associated with levels >1200 U/L. Conclusions: GP levels was associated to some of the manifestations of dengue. This finding suggests that the intensity of oxidative stress can influence the clinical presentation of dengue
Correlación entre los niveles de glutatión peroxidasa, un marcador de estrés oxidativo, y la presentación clínica del dengue
Rojas,Elsa Marina; Díaz-Quijano,Fredi Alexander; Coronel-Ruiz,Carolina; Martínez-Vega,Ruth Aralf; Rueda,Ernesto; Villar-Centeno,Luis ángel;
Revista médica de Chile , 2007, DOI: 10.4067/S0034-98872007000600008
Abstract: background: glutathione peroxidase (gp) can be used as a marker of oxidative stress in infectious diseases. aim: to evaluate the association between the levels of glutathione peroxidase (gp) and the manifestations and complications of dengue. patients and methods: between april 2003 and december 2004, 161 patients with dengue were prospectively evaluated. in the first evaluation, within 48 and 96 hours of disease onset, a plasma sample was obtained to measure the gp levels. the association between gp levels, clinical manifestations and complications was evaluated during the follow up. results: mean gp values were 1198 u/l (95% confidence interval 1089-1306). values greater than 1200 u/l were associated with headache, arthralgias and increased heart rate. there was a negative association between gp levels and serum triglycerides. during follow up, patients with gp >1200 u/l had a higher frequency of spontaneous hemorrhages. in a logistic regression analysis arthralgias, fever and increased heart rate, were independently associated with levels >1200 u/l. conclusions: gp levels was associated to some of the manifestations of dengue. this finding suggests that the intensity of oxidative stress can influence the clinical presentation of dengue
Assessment of psychiatric disorders in vitiligo. Conclusions for our daily practice
Marina Rodríguez-Martín,Desiré Díaz Melián,Miguel Sáez Rodríguez,Antonio Noda Cabrera
Our Dermatology Online , 2012,
Abstract:
Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup
Leonardo Lorente, Ruth Iceta, María M Martín, Esther López-Gallardo, Jordi Solé-Violán, José Blanquer, Lorenzo Labarta, César Díaz, Alejandro Jiménez, Julio Montoya, Eduardo Ruiz-Pesini
Critical Care , 2012, DOI: 10.1186/cc11150
Abstract: A prospective, multicenter, observational study was carried out in six Spanish ICUs. We included 96 patients with severe sepsis. We determined the mtDNA haplogroup, the COX specific activity/citrate synthase specific activity (COXa/CSa) ratio and the COX quantity/citrate synthase specific activity (COXq/CSa) ratio in circulating platelets at the time of diagnosis, day 4 and day 8. We used survival at 1 and 6 months as endpoints.Patients with the JT mtDNA haplogroup (n = 15) showed higher COXq/CSa ratio at day 4 (P = 0.04) and day 8 (P = 0.02) than those with other haplogroups (n = 81). Logistic regression analysis showed that the JT mtDNA haplogroup (odds ratio = 0.18; 95% confidence interval = 0.04 to 0.94; P = 0.04) and COXq/CSa ratio (odds ratio = 0.53; 95% confidence interval = 0.30 to 0.93; P = 0.03) were associated with 1-month survival after controlling for age and lactic acid levels.The novel findings of our study are that 1-month surviving septic patients showed higher COXq/CSa ratio than nonsurviving individuals, that patients from the JT mtDNA haplogroup showed a higher COXq/CSa ratio and that JT patients had a higher 1-month survival than patients from other mtDNA haplogroups.Sepsis is a common, expensive, and frequently fatal condition [1,2]. The physiopathologic mechanisms of sepsis are not well known, but it has been proposed that organ dysfunction during sepsis is associated with tissue hypoxia due to cellular inability to use oxygen because of mitochondrial dysfunction [3]. Respiratory complex IV or cytochrome c oxidase (COX) is responsible for most cellular oxygen consumption. We have recently found that platelet COX activities and quantities in 6-month-survival patients are significantly higher than those of patients who do not survive 6 months [4]. COX contains 13 polypeptides and three of them are encoded by mitochondrial DNA (mtDNA) [5]. We have also found that transmitochondrial cell lines (cybrids) harboring different mtDNA genetic background
Relación entre hiperinsulinemia, disfunción diastólica e hipertrofia del ventrículo izquierdo en pacientes con hipertensión arterial sistémica
Cardona-Mu?oz,Ernesto Germán; Cardona-Müller,David; Totsuka-Sutto,Sylvia; Nu?o-Guzmán,Carlos Martín; Pascoe-González,Sara; Romero-Prado,Marina; Miranda-Díaz,Alejandra G;
Revista médica de Chile , 2007, DOI: 10.4067/S0034-98872007000900005
Abstract: background: hypertension is the main independent cardiovascular risk factor. however, there are additional factors that induce organic damage. aim: to assess the association between hyperinsulinemia, ventricular hypertrophy and left ventricular diastolic function. patients and methods: seventy-four patients aged 30 to 65 years, with mild or moderate systemic hypertension, with overweight or mild obesity and normal glucose tolerance curve (gtc), were studied. serum insulin was measured during gtc. the maximum levels of insulin and glucose were observed 60 minutes after the oral glucose load and they were expressed as rg/1. patients were stratified in three groups according to their glucose and insulin fasting levels (i0) and post-glucose challenge levels (rg/i): group 1 (normoinsulinemic patients) i0 <17 mu/ml and rg/i >2 (2.45+0.4). group 2 (post-prandial hyperinsulinemic patients) i0 <17 mu/ml and rg/i <2> 1 (1.34+0.3). group 3 (persistently hyperinsulinemic patients) i0 >17 mu/ml and <1 (0.7+0.3). left ventricular mass and its diastolic function were measured by doppler echocardiography. results: no differences in blood pressure or age were observed between groups. there was a negative correlation between ventricular mass and rg/1 (r =-0.282, p =0.015). left ventricular diastolic dysfunction was significantly more deteriorated in group 3, as compared with group 1 (p <0.001 anova). there was a significant correlation between g/gi and diastolic dysfunction (r =0.232 p =0.047). conclusions: fasting, post challenge hyperinsulinemia and a rg/i <1 are associated with higher ventricular mass and left ventricular diastolic dysfunction, independent of blood pressure and age (rev méd chile 2007; 135: 1125-31)
No Evidence of Association between Common Autoimmunity STAT4 and IL23R Risk Polymorphisms and Non-Anterior Uveitis
María Carmen Cénit, Ana Márquez, Miguel Cordero-Coma, Marina Bego?a Gorro?o-Echebarría, Alejandro Fonollosa, Alfredo Adán, Agustín Martínez-Berriotxoa, David Díaz Valle, Esperanza Pato, Ricardo Blanco, Joaquín Ca?al, Manuel Díaz-Llopis, José Luis García Serrano, Enrique de Ramón, María José del Rio, José Manuel Martín-Villa, Blanca Molins, Norberto Ortego-Centeno, Javier Martín
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0072892
Abstract: Objective STAT4 and IL23R loci represent common susceptibility genetic factors in autoimmunity. We decided to investigate for the first time the possible role of different STAT4/IL23R autoimmune disease-associated polymorphisms on the susceptibility to develop non-anterior uveitis and its main clinical phenotypes. Methods Four functional polymorphisms (rs3821236, rs7574865, rs7574070, and rs897200) located within STAT4 gene as well as three independent polymorphisms (rs7517847, rs11209026, and rs1495965) located within IL23R were genotyped using TaqMan? allelic discrimination in a total of 206 patients with non-anterior uveitis and 1553 healthy controls from Spain. Results No statistically significant differences were found when allele and genotype distributions were compared between non-anterior uveitis patients and controls for any STAT4 (rs3821236: P=0.39, OR=1.12, CI 95%=0.87-1.43; rs7574865: P=0.59 OR=1.07, CI 95%=0.84-1.37; rs7574070: P=0.26, OR=0.89, CI 95%=0.72-1.10; rs897200: P=0.22, OR=0.88, CI 95%=0.71-1.08;) or IL23R polymorphisms (rs7517847: P=0.49, OR=1.08, CI 95%=0.87-1.33; rs11209026: P=0.26, OR=0.78, CI 95%=0.51-1.21; rs1495965: P=0.51, OR=0.93, CI 95%=0.76-1.15). Conclusion Our results do not support a relevant role, similar to that described for other autoimmune diseases, of IL23R and STAT4 polymorphisms in the non-anterior uveitis genetic predisposition. Further studies are needed to discard a possible weak effect of the studied variant.
Susceptibilidad a la nistatina de aislamientos bucales de Candida y su correlación con la respuesta al tratamiento
Prieto Santa Anna,Luz Marina; Díaz Suárez,Luis Alberto; Illnait Zaragozí,Maria Teresa; Perurena Lancha,Mayda Rosa; Cantelar de Francisco,Nereyda; Fernández Andreu,Carlos Manuel; Martínez Machín,Gerardo;
Revista Cubana de Medicina Tropical , 2010,
Abstract: introduction: oropharyngeal candidiasis is an early marker of progression to aids in hiv-positive patients and an indicator of non-adherence of treatment or possible failure in patients undergoing anti-retroviral therapy. objective: to determine the in vitro susceptibility to nystatin in candida strains isolated from the oral cavity of hiv-positive patients, and to correlate the results with the response to treatment. methods: a study of in vitro susceptibility to nystatin was conducted in 104 oral isolates from 97 hiv/aids patients, who participated as volunteers in a clinical trial to evaluate the response to four antifungal drugs. fifty-eight of the 104 isolates were obtained before starting treatment and the remaining 46 at the end of therapy. broth microdilution method was performed according to the document m27-a3 of the clinical and laboratory standards institute. results: one hundred percent of the strains were susceptible to nystatin, with minimum inhibitory concentration (mic) values of <16 μg/ml, regardless of the time of isolation and of the drug administered to patients. in the group of patients treated with nystatin, the mic80 ranges (1-2 μg/ml), geometric mean and cumulative values of the drug against candida albicans isolates before starting treatment were similar to those obtained against strains recovered at the end. among the identified species, c. lusitaniae reached the highest absolute mic value (4 μg/ml). conclusions: the correlation between the clinical evolution and the results of in vitro susceptibility tests was good in patients with a favorable outcome; however, it did not allow predicting possible treatment failure.
Random Route and Quota Sampling: Do They Offer Any Advantage over Probably Sampling Methods?  [PDF]
Vidal Díaz de Rada, Valentín Martínez Martín
Open Journal of Statistics (OJS) , 2014, DOI: 10.4236/ojs.2014.45038
Abstract:

The aim of this paper is to compare sample quality across two probability samples and one that uses probabilistic cluster sampling combined with random route and quota sampling within the selected clusters in order to define the ultimate survey units. All of them use the face-to-face interview as the survey procedure. The hypothesis to be tested is that it is possible to achieve the same degree of representativeness using a combination of random route sampling and quota sampling (with substitution) as it can be achieved by means of household sampling (without substitution) based on the municipal register of inhabitants. We have found such marked differences in the age and gender distribution of the probability sampling, where the deviations exceed 6%. A different picture emerges when it comes to comparing the employment variables, where the quota sampling overestimates the economic activity rate (2.5%) and the unemployment rate (8%) and underestimates the employment rate (3.46%).

Two Functional Variants of IRF5 Influence the Development of Macular Edema in Patients with Non-Anterior Uveitis
Ana Márquez, María Carmen Cénit, Miguel Cordero-Coma, Norberto Ortego-Centeno, Alfredo Adán, Alejandro Fonollosa, David Díaz Valle, Esperanza Pato, Ricardo Blanco, Joaquín Ca?al, Manuel Díaz-Llopis, Enrique de Ramón, María José del Rio, José Luis García Serrano, Joseba Artaraz, José Manuel Martín-Villa, Víctor Lloren?, Marina Bego?a Gorro?o-Echebarría, Javier Martín
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0076777
Abstract: Objective Interferon (IFN) signaling plays a crucial role in autoimmunity. Genetic variation in interferon regulatory factor 5 (IRF5), a major regulator of the type I interferon induction, has been associated with risk of developing several autoimmune diseases. In the current study we aimed to evaluate whether three sets of correlated IRF5 genetic variants, independently associated with SLE and with different functional roles, are involved in uveitis susceptibility and its clinical subphenotypes. Methods Three IRF5 polymorphisms, rs2004640, rs2070197 and rs10954213, representative of each group, were genotyped using TaqMan? allelic discrimination assays in a total of 263 non-anterior uveitis patients and 724 healthy controls of Spanish origin. Results A clear association between two of the three analyzed genetic variants, rs2004640 and rs10954213, and the absence of macular edema was observed in the case/control analysis (PFDR=5.07E-03, OR=1.48, CI 95%=1.14-1.92 and PFDR=3.37E-03, OR=1.54, CI 95%=1.19-2.01, respectively). Consistently, the subphenotype analysis accordingly with the presence/absence of this clinical condition also reached statistical significance (rs2004640: P=0.037, OR=0.69, CI 95%=0.48-0.98; rs10954213: P=0.030, OR=0.67, CI 95%=0.47-0.96), thus suggesting that both IRF5 genetic variants are specifically associated with the lack of macular edema in uveitis patients. Conclusion Our results clearly showed for the first time that two functional genetic variants of IRF5 may play a role in the development of macular edema in non-anterior uveitis patients. Identifying genetic markers for macular edema could lead to the possibility of developing novel treatments or preventive therapies.
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