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Search Results: 1 - 10 of 192072 matches for " Dájer "
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Analysis of nuclear fiber cell compaction in transparent and cataractous diabetic human lenses by scanning electron microscopy
Christopher D Freel, Kristin J Al-Ghoul, Jer R Kuszak, M Joseph Costello
BMC Ophthalmology , 2003, DOI: 10.1186/1471-2415-3-1
Abstract: Transparent and nuclear cataractous lenses from diabetic patients were examined by scanning electron microscopy (SEM). Measurements of the fetal nuclear (FN) elliptical angles (anterior and posterior), embryonic nuclear (EN) anterior-posterior (A-P) axial thickness, and the number of EN fiber cell membrane folds over 20 μm were compared.Diabetic lenses with nuclear cataract exhibited smaller FN elliptical angles, smaller EN axial thicknesses, and larger numbers of EN compaction folds than their non-cataractous diabetic counterparts.As in non-diabetic lenses, the inner nuclei of cataractous lenses from diabetics were significantly more compacted than those of non-cataractous diabetics. Little difference between diabetic and non-diabetic compaction levels was found, suggesting that diabetes does not affect the degree of compaction. However, consistent with previous proposals, diabetes does appear to accelerate the formation of cataracts that are similar to age-related nuclear cataracts in non-diabetics. We conclude that as scattering increases in the diabetic lens with cataract formation, fiber cell compaction is significant.The normal human ocular lens exhibits a steady increase in size due to growth throughout life, harboring some the oldest cells in the body [1-3]. Overall, from birth to 65 years of age, the human lens will increase 63% in equatorial diameter, while increasing only 22% in A-P axial thickness [4]. Cell growth dramatically influences the contours of the anterior and posterior lens surfaces, but is not the sole factor affecting lens form.Previous studies investigating the hydration of transparent human lenses revealed an age-related dependence between water content and lens region [5]. With advancing age, the human lens cortex shows a slight increase in water composition (+0.0087%/year), whereas the nucleus decreases its total water content (-0.077%/year), setting up a gradient of hydration [5]. Studies of human diabetic lenses have revealed greater t
Poligrafía respiratoria en el diagnóstico de los trastornos respiratorios durante el sue?o: Una herramienta necesaria para el neumonólogo
Borsini,Eduardo; Bosio,Martín; Quadrelli,Silvia; Campos,Jerónimo; Décima,Tamara; Chertcoff,Julio;
Revista americana de medicina respiratoria , 2012,
Abstract: the respiratory polygraphy (rp) is a useful method for the diagnosis of sleep apnea when it is indicated in high risk patients and meets basic technical requirements for quality. when rp is interpreted in conjunction with a comprehensive evaluation of sleep, it shortens waiting lists approaching the sleep laboratory to the home, and allows the assessment of respiratory performance during sleep in a more natural environment under usual conditions similar to those when the patient is ready to sleep. technological developments have brought a considerable reduction in size and weight and in the costs of the recording devices, which can be used bedside and connected to therapeutics devices (cpap or non invasive ventilator). also, they have increased the accessibility to diagnostic process of small units with limited technical resources expanding the diagnostic horizon of the pulmonologist. the polygraphy or polysomnography is still very important to define with certainty doubtful cases and it is the standard method which should be taken to assess the progress of new accessible methods for the study of these diseases.
Medicina y Seguridad del Trabajo, evaluación desde su ingreso en la Red SciELO (Scientific Electronic Library Online)
Bernal Zamora,Ascensión; Maqueda Blasco,Jerónimo; Veiga de Cabo,Jorge; D'Agostino,Marcelo;
Medicina y Seguridad del Trabajo , 2012, DOI: 10.4321/S0465-546X2012000100001
Abstract: this editorial is a review of key content and editorial changes suffered by the medicina y seguridad del trabajo for the past 5 years, coinciding with the period since joining scielo (scientific electronic library online) (2007-2011). in the study period there have been more of 190,000 articles access, an impact factor (if) scielo of 1.22, increase the number of articles received from different countries of america and europe and the journal has been indexed in various international bibliographic databases (scielo, directory of open access journals (doaj), google schoolar, eprints in library and information science (e-lis) and latindex) and national (ibecs, emi, base data national research council (csic), and cuiden dialnet). editorial quality and contents have also been enhanced with various modifications and changes, and the pan american health organization, regional office for the americas of the world health organization (paho/who) is involved in the journal edition. there was an increase of over 40% of articles published in the last five years compared to previous period, from 118 to 202 items. the number of editorials and clinical cases are also increasing at a rate of 40%. original articles are increased by just over 50% (53 versus 109), finding the largest increase in review articles (3 in the first period and 25 in the last five-years study period). finally, in 2011, medicina y seguridad del trabajo has first published a special number about psychosocial factors, and mental health occupational health including 15 review articles on current topics by specialists in the field. this results, encourage editorial team eagerness to continue working to improve quality and visibility of the journal over the coming years.
Medicina y Seguridad del Trabajo, evaluación desde su ingreso en la Red SciELO (Scientific Electronic Library Online) Medicina y Seguridad del Trabajo, evaluation since joining SciELO (Scientific Electronic Library Online)
Ascensión Bernal Zamora,Jerónimo Maqueda Blasco,Jorge Veiga de Cabo,Marcelo D'Agostino
Medicina y Seguridad del Trabajo , 2012,
Abstract: Se realiza una revisión de los principales cambios editoriales y de contenido sufridos por la revista de Medicina y Seguridad del Trabajo durante los últimos 5 a os, coincidiendo con el periodo desde que ingresó en SciELO (ScientificElectronic Library Online) (2007-2011). En el periodo estudiado se han realizado un número de consultas a sus artículos superior a los 190 mil, ha tenido un Factor de Impacto (FI) SciELO del 1.22, se ha incrementado el número de artículos recibidos de diferentes países de América y Europa y se la revista ha sido indizada en diferentes Bases de Datos bibliográficas internacionales (SciELO, Directory of Open Access Journals (DOAJ), Google Schoolar, Eprints in Library and InformationScience (E-LIS) y LATINDEX) y nacionales (IBECS, IME, Base de Datos del Consejo Superior de Investigaciones Científicas (CSIC), DIALNET y CUIDEN). La calidad editorial y de contenidos también se han visto mejoradas con diferentes modificaciones y cambios introducidos. Se cuenta con la participación editorial de la Organización Panamericana de la Salud, Oficina regional para las Américas de la Organización M undial del Salud (OPS/OMS), se ha producido un incremento superior al 40% de los artículos publicados en el último quinquenio respecto al periodo anterior, pasando de 118 a 202 artículos. El número de Editoriales y casos Clínicos también se incrementan en un porcentaje del 40 %. Los Artículos Originales se incrementan en algo más del 50% (53 versus 109), encontrando el mayor incremento en los Artículos de revisión que pasan de 3 en el primer anterior a 25 en el periodo de estudio. Por último, en 2011, Medicina y Seguridad en el Trabajo ha publicado por primera vez un número monográfico especial sobre Factores Psicosociales, Salud laboral y Salud Mental que incluye 15 artículos de revisión sobre temas de actualidad realizados por especialistas en la materia. Los resultados estimulan el afán por del Equipo Editorial por seguir trabajando para mejorar de calidad y visibilidad de la revista durante los próximos a os. This Editorial is a review of key content and editorial changes suffered by the Medicina y Seguridad del Trabajo for the past 5 years, coinciding with the period since joining SciELO (Scientific Electronic Library Online) (2007-2011). In the study period there have been more of 190,000 articles access, an impact factor (IF) SciELO of 1.22, increase the number of articles received from different countries of America and Europe and the journal has been indexed in various international bibliographic databases (SciELO, Directory of Open Acces
El portal InfoSaludLaboral, una nueva cara, un nuevo reto Webpage InfoSaludLaboral, a new face, a new challenge
Jorge Veiga de Cabo,Jerónimo Maqueda Blasco,Marcelo D'Agostino,Paulo Leite
Medicina y Seguridad del Trabajo , 2011,
Abstract:
High-speed kymography identifies the immediate effects of voiced vibration in healthy vocal folds
Pimenta, Regina Aparecida,Dájer, María Eugenia,Hachiya, Adriana,Cordeiro, Gislaine Ferro
International Archives of Otorhinolaryngology , 2013,
Abstract: Introduction: The effects of voiced vibration technique can be assessed by laryngeal imaging. Kymographic images derived from high-speed videoendoscopy allow actual visualization of vocal folds vibration. Purpose: The aim of this study is to identify the immediate effects of the voiced vibration technique in healthy vocal folds using high-speed digital laryngeal imaging. Methods: Samples were obtained from 15 healthy subjects with no history of voice disorders (6 men and 9 women aged 21 to 43 years). High-speed videoendoscopy recordings were performed before and after the voiced vibration technique. Kymographic images were obtained using high-speed videoendoscopy. The vocal folds were examined in their open and closed positions and the characteristics of the opening and closing phases were determined. A customize computational routine was used quantify these parameters. The closing, opening, and speed quotients were also calculated. Results: In this study, women displayed statistically significant differences in opened phase (P= 0.05*), closed phase (P= 0.046*), and closing phase (P= 0.026*) phase characteristics. Men displayed the highest difference rate in opening time characteristics (P= 0.06). The closing and opening quotients for the female group showed significant differences (P= 0.029* and P= 0.049*, respectively). The speed quotient exhibited statistically significant differences in the male group (P= 0.048*). Conclusion: The kymographic images indicated that the immediate effect of the voiced vibration technique was smooth contact in healthy vocal fold vibration.
High-speed kymography identifies the immediate effects of voiced vibration in healthy vocal folds
Pimenta, Regina Aparecida;Dájer, María Eugenia;Hachiya, Adriana;Cordeiro, Gislaine Ferro;Tsuji, Domingos Hiroshi;Montagnoli, Arlindo Neto;
International Archives of Otorhinolaryngology , 2013, DOI: 10.7162/S1809-97772013000100013
Abstract: introduction: the effects of voiced vibration technique can be assessed by laryngeal imaging. kymographic images derived from high-speed videoendoscopy allow actual visualization of vocal folds vibration. purpose: the aim of this study is to identify the immediate effects of the voiced vibration technique in healthy vocal folds using high-speed digital laryngeal imaging. methods: samples were obtained from 15 healthy subjects with no history of voice disorders (6 men and 9 women aged 21 to 43 years). high-speed videoendoscopy recordings were performed before and after the voiced vibration technique. kymographic images were obtained using high-speed videoendoscopy. the vocal folds were examined in their open and closed positions and the characteristics of the opening and closing phases were determined. a customize computational routine was used quantify these parameters. the closing, opening, and speed quotients were also calculated. results: in this study, women displayed statistically significant differences in opened phase (p= 0.05*), closed phase (p= 0.046*), and closing phase (p= 0.026*) phase characteristics. men displayed the highest difference rate in opening time characteristics (p= 0.06). the closing and opening quotients for the female group showed significant differences (p= 0.029* and p= 0.049*, respectively). the speed quotient exhibited statistically significant differences in the male group (p= 0.048*). conclusion: the kymographic images indicated that the immediate effect of the voiced vibration technique was smooth contact in healthy vocal fold vibration.
Exposure of pampas fox (Pseudalopex gymnocercus) and crab-eating fox (Cerdocyon thous) from the Southern region of Brazil to Canine distemper virus (CDV), Canine parvovirus (CPV) and Canine coronavirus (CCoV)
Hübner, Silvia de Oliveira;Pappen, Felipe Geraldes;Ruas, Jer?nimo Lopes;Vargas, Gilberto D'ávila;Fischer, Geferson;Vidor, Telmo;
Brazilian Archives of Biology and Technology , 2010, DOI: 10.1590/S1516-89132010000300012
Abstract: the exposure of 13 brazilian free-ranging nondomestic canids (five pampas fox - pseudalopex gymnocercus and eight crab-eating fox -cerdocyon thous) from southern region of brazil, to canine distemper virus (cdv), canine parvovirus (cpv) and canine coronavirus (ccov) was investigated. antibodies against cdv were detected in 38.5% (5/13) of the samples. there were anti-cdv antibodies in 60% (3/5) of p. gymnocercus and in 25% (2/8) of c. thous. the frequency was higher among the adults and males. eleven canids (84.6%) presented antibodies against cpv, 80% (4/5) were from p. gymnocercus and 87.5% (7/8) were from c. thous. there was no difference in positivity rate against cpv between gender and age. antibodies against ccov were detected in 38.5% (5/13) of the samples, with 60% (3/5) of positivity in p. gymnocercus and 25% (2/8) in c. thous. the frequency of antibodies against ccov was higher among the adults and males. the study showed that these canids were exposed to cdv, cpv and ccov.
Velocidade do som no ar: um experimento caseiro com microcomputador e balde d'água
Silva Wilton Pereira da,Silva Cleide M. D. P. S. e,Fereira Tarso V.,Rocha Jer?nimo S.
Revista Brasileira de Ensino de Física , 2003,
Abstract: Este artigo prop e um experimento caseiro para a determina o da velocidade do som no ar. Para tal, foi desenvolvido um programa de computador para a gera o de áudio em freqüências estabelecidas pelo usuário, e também para a apresenta o dos roteiros experimentais (ensino médio e superior). O experimento proposto foi realizado por diversos alunos, em suas próprias casas, e os resultados obtidos concordam com os valores esperados.
Dual Roles of METCAM in the Progression of Different Cancers
Guang-Jer Wu
Journal of Oncology , 2012, DOI: 10.1155/2012/853797
Abstract: METCAM, an integral membrane cell adhesion molecule (CAM) in the Ig-like gene superfamily, is capable of performing typical functions of CAMs, such as mediating cell-cell and cell-extracellular interactions, crosstalk with intracellular signaling pathways, and modulating social behaviors of cells. METCAM is expressed in about nine normal cells/tissues. Aberrant expression of METCAM has been associated with the progression of several epithelial tumors. Further in vitro and in vivo studies show that METCAM plays a dual role in the progression of different tumors. It can promote the malignant progression of several tumors. On the other hand, it can suppress the malignant progression of other tumors. We suggest that the role of METCAM in the progression of different cancer types may be modulated by different intrinsic factors present in different cancer cells and also in different stromal microenvironment. Many possible mechanisms mediated by this CAM during early tumor development and metastasis are suggested. 1. Introduction Human METCAM (huMETCAM), a CAM in the immunoglobulin-like gene superfamily, is an integral membrane glycoprotein. Alternative names for METCAM are MUC18 [1], CD146 [2], MCAM [3], MelCAM [4], A32 [5], and S-endo 1 [6]. To avoid confusion with mucins and to reflect its biological functions, we have renamed MUC18 as METCAM (metastasis CAM), which means an immunoglobulin-like CAM that affects or regulates metastasis, [7]. The huMETCAM has 646 aminoacids that include a N-terminal extracellular domain of 558 aminoacids, which has 28 aminoacids characteristics of a signal peptide sequence at its N-terminus, a transmembrane domain of 24 aminoacids (amino acid number 559–583), and a cytoplasmic domain of 64 aminoacids at the C-terminus. HuMETCAM has eight putative N-glycosylation sites (Asn-X-Ser/Thr), of which six are conserved, and are heavily glycosylated and sialylated resulting in an apparent molecular weight of 113,000–150,000. The extracellular domain of the protein comprises five immunoglobulin-like domains (V-V-C2-C2-C2) [1, 7] and an X domain [7]. The cytoplasmic tail contains peptide sequences that will potentially be phosphorylated by protein kinase A (PKA), protein kinase C (PKC), and casein kinase 2 (CK 2) [1, 7, 8]. My lab has also cloned and sequenced the mouse METCAM (moMETCAM) cDNA, which contains 648 aminoacids with a 76.2% identity with huMETCAM, suggesting that moMETCAM is likely to have biochemical properties and biological functions similar to the human counterpart [9]. The structure of the huMETCAM protein is depicted
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