Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99


Any time

2020 ( 1 )

2019 ( 189 )

2018 ( 1485 )

2017 ( 1337 )

Custom range...

Search Results: 1 - 10 of 80797 matches for " CunXia Liu "
All listed articles are free for downloading (OA Articles)
Page 1 /80797
Display every page Item

Liu Cunxia,

光子学报 , 1996,
Abstract: In this paper,the theory of middle orbit is generalized to satellite orbit calculation in generalized relativity.Integrals of relativistic middle orbit are given,and the perturbation motion equations with orbit parameters as variates are obtained.
Candidate Genes Polymorphism and Its Association to Prolificacy in Chinese Goats
Yuanqing He,Xiaoke Ma,Xiaoyong Liu,Cunxia Zhang
Journal of Agricultural Science , 2010, DOI: 10.5539/jas.v2n1p88
Abstract: To find the candidate gene concerned with prolificacy in goats, the most part nucleotide sequence of four genes, including GDF9 gene, BMP15 gene, BMPR1B gene, and INH? gene were identified in three goat breeds for their probable association to the high fecundity. The results showed that none of polymorphism of GDF9 gene, BMP15 gene and BMPR1B gene was tested in goats, and one mutation was detected in INH? gene. The genotype distributions of INH? gene were significantly difference between year-round estrous goat breeds and seasonal estrous goat breeds revealing the association to the prolificacy in goats.
Efficacy of seasonal pandemic influenza hemagglutinin DNA vaccines delivered by electroporation against aseasonal H1N1 virus challenge in mice
Lei Tan,HuiJun Lu,Dan Zhang,KaiYan Wang,MingYao Tian,CunXia Liu,YanYu LiU,Bo Hu,NingYi Jin
Science China Life Sciences , 2011, DOI: 10.1007/s11427-011-4150-5
Abstract: Prophylactic DNA vaccines against the influenza virus are promising alternatives to conventional vaccines. In this study, we generated two candidate gene-based influenza vaccines encoding either the seasonal or pandemic hemagglutinin antigen (HA) from the strains A/New Caledonia/20/99 (H1N1) (pV1A5) and A/California/04/2009 (H1N1) (pVEH1), respectively. After verifying antigen expression, the immunogenicity of the vaccines delivered intramuscularly with electroporation was tested in a mouse model. Sera of immunized animals were tested in hemagglutination inhibition assays and by ELISA for the presence of HA-specific antibodies. HA-specific T-cells were also measured in IFN-γ ELISpot assays. The protective efficacy of the candidate influenza vaccines was evaluated by measuring mortality rates and body weight after a challenge with 100 LD50 of mouse-adapted A/New Caledonia/20/99 (H1N1). Mice immunized with either one of the two vaccines showed significantly higher T cell and humoral immune responses (P<0.05) than the pVAX1 control group. Additionally, the pV1A5 vaccine effectively protected the mice against a lethal homologous mouse-adapted virus challenge with a survival rate of 100% compared with a 40% survival rate in the pVEH1 vaccinated group (P<0.05). Our study indicates that the seasonal influenza DNA vaccine completely protects against the homologous A/New Caledonia/20/99 virus (H1N1), while the pandemic influenza DNA vaccine only partially protects against this virus.
Immunogenicity of Foot and Mouth Disease Virus Type Asia 1 Protein VP1-2A Fused with a Multi-Epitope Expressed in Pichia pastoris
Zhan-Bo Zhu,Ying Xi,Bo Hu,Chang Li,Huijun Lu,Kuoshi Jin,Jingqiang Ren,Cunxia Liu,Minglan Jin,Ningyi Jin
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2012.1512.1517
Abstract: Foot and Mouth Disease (FMD) is a highly infectious and economically devastating disease of livestock. A genetically engineered vaccine against Foot and Mouth Disease Virus (FMDV) may be a good control measure for use during an epidemic. In this study, a secretory expression vector, pPIC9K-VP1-2A-CTE, containing a fusion of the bovine (FMDV) type Asia 1 VP1-2A gene and a multi-epitope CTB-TEpi (CTE) was constructed. After being linearized with Sal I, the recombinant plasmid was transformed into Pichia pastoris GS115 by electroporation. The fusion protein expressed in yeast was analyzed by SDS-PAGE and Western blot and immunogenicity of the fusion protein was assessed. The expressed recombinant VP1-2A and CTE protein elicited specific humoral and cellular immune responses in mice. Additionally, immunized guinea pigs were protected when challenged with the FMD Asia 1 virus.
Protection against SHIV-KB9 Infection by Combining rDNA and rFPV Vaccines Based on HIV Multiepitope and p24 Protein in Chinese Rhesus Macaques
Chang Li,Zhenwei Shen,Xiao Li,Jieying Bai,Lin Zeng,Mingyao Tian,Ying Jin Song,Ming Ye,Shouwen Du,Dayong Ren,Cunxia Liu,Na Zhu,Dandan Sun,Yi Li,Ningyi Jin
Clinical and Developmental Immunology , 2012, DOI: 10.1155/2012/958404
Abstract: Developing an effective vaccine against HIV infection remains an urgent goal. We used a DNA prime/fowlpox virus boost regimen to immunize Chinese rhesus macaques. The animals were challenged intramuscularly with pathogenic molecularly cloned SHIV-KB9. Immunogenicity and protective efficacy of vaccines were investigated by measuring IFN- levels, monitoring HIV-specific binding antibodies, examining viral load, and analyzing CD4/CD8 ratio. Results show that, upon challenge, the vaccine group can induce a strong immune response in the body, represented by increased expression of IFN-, slow and steady elevated antibody production, reduced peak value of acute viral load, and increase in the average CD4/CD8 ratio. The current research suggests that rapid reaction speed, appropriate response strength, and long-lasting immune response time may be key protection factors for AIDS vaccine. The present study contributes significantly to AIDS vaccine and preclinical research.
The Model of Mobile Knowledge Services System in the Management of Complex Cluster Project  [PDF]
Yong Liu, Bingxin Liu
iBusiness (IB) , 2011, DOI: 10.4236/ib.2011.31006
Abstract: Cluster projects are projects of large-scale or with huge investment, such as Beijing 2008 Olympic Games and Shanghai 2010 Expo. A lot of on-site management works are involved in the process of cluster project management, especially the treatment of sudden accidents which would produce plenty of knowledge and experience. As cluster project on-site management spots change frequently, knowledge produced by mobile workers in the process of on-site management is hard to be saved into the knowledge repository on time. It may cause a knowledge distortion or even missing. On the other hand, in the process of cluster project management, a lot of knowledge is required by on-site workers to deal with on-site activities. However, due to lack of effective mechanisms for knowledge communion, they often face the risk of making wrong decisions. To solve the problems of knowledge management and acquisition in the process of cluster project on-site management, this paper presents a system model for mobile knowledge service.
The Collusion Deterrence with Prisoner’s Dilemma  [PDF]
Aidong Liu, Jinfang Liu
Journal of Service Science and Management (JSSM) , 2010, DOI: 10.4236/jssm.2010.34053
Abstract: I tried to present a new method to prevent collusion through employing two auditors at the same time and inspiring them provide true report by exploiting their prisoner’s dilemma. But I found this method cannot be put into practice because of the high cost. So I analyzed whether sending the second auditor in a probability, a low cost method, can deter the audit collusion. I find sending the second auditor in a probability, enforcing the rigidly lawful punishment and perfecting the reward mechanism can prevent audit collusion. I also find the auditor’s ethical constraint do good to prevent collusion and the charger of state assets management can play the same role as the real owner of the state-owned enterprise in deterring collusion. This finding provides theory support for the government to implement the publicly audit bidding and random double auditing system on state-owned enterprise. The supervision of PCAOB on auditors is also the operation of this theory.
Using Insulation in China’s Buildings: Potential for Significant Energy Savings and Carbon Emission Reductions  [PDF]
Guoliang Liu, Hans Liu
Low Carbon Economy (LCE) , 2011, DOI: 10.4236/lce.2011.24027
Abstract: Most old residential and commercial buildings in China are not insulated or not to new standards. This is true even in regions with very cold winters or regions with very hot summers. The insulation in new buildings is very poor relative to North American standards. However, insulating the exterior walls, attic roofs, and foundation walls to new standards of buildings in China would reduce the need for heating and air conditioning, and thus would save roughly 200 million tons of coal each year. This in turn would lead to a reduction in CO2 emissions of about 510 million tons per year, which is equal to about 8.4% of China’s total carbon emissions in 2006. The use of insulation in buildings will help homeowners save money, help China save energy and help the environment all at the same time. Insulation will provide a continued payback to the homeowner, not only in dollars and cents, but also by providing a more enjoyable and comfortable living environment for many years.
An Elementary Introduction to Training the Postgraduates for Professional Degrees in Oil and Gas Engineering  [PDF]
Qingyou Liu, Zhibin Liu
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.326126
Abstract: The demand of the talents in petroleum engineering of petroleum enterprises is analyzed in this paper according the current situation of the engineering education. The four levels of the professional talents needed by the petroleum enterprises are specified, which makes it clear that what the purpose and orientation of the higher education in petroleum engineering should be. The qualities of the petroleum engineers are discussed specifically and it is pointed out that the training of the postgraduate for professional degree in oil and gas engineering should be the cradle of the petroleum engineers. A training schedule is listed in this paper based on the discussion, including curriculum provision, practice link, thesis and training mode, which will be a pathfinder of the education of the professional degree graduate student in oil and gas engineering. Moreover, the practice can provide useful experience for the training and education of different type of graduates.
Overall Framework and Module of Distribution Network Coordinated Planning Considering Distributed Generation  [PDF]
Qianjin LIU, Huanghuang LIU
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.51B006
Abstract: Combining with the characteristics of China's energy and the strategy of sustainable development, analyzing the pros and cons which caused by the appearance of DG and their operation connecting to grid, this paper points out that the two sides can achieve win-win under a reasonable combination between DG and distribution system, so as to optimize the allocation of resources, improve the utilization ratio of resource, and obtain maximum social benefit, harmoniously promote the development of power industry, economy and environment. As a word, this paper puts forward a new model of distribution network planning including DG and brings in penalty factorto guide the investment and construction of DG. Last of all, this paper presents the adoption of the coordination development coefficients which is to evaluate the power planning.
Page 1 /80797
Display every page Item

Copyright © 2008-2017 Open Access Library. All rights reserved.