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Search Results: 1 - 10 of 24107 matches for " Cristina Rodriguez-Fontenla "
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New Sequence Variants in HLA Class II/III Region Associated with Susceptibility to Knee Osteoarthritis Identified by Genome-Wide Association Study
Masahiro Nakajima,Atsushi Takahashi,Ikuyo Kou,Cristina Rodriguez-Fontenla,Juan J. Gomez-Reino,Tatsuya Furuichi,Jin Dai,Akihiro Sudo,Atsumasa Uchida,Naoshi Fukui,Michiaki Kubo,Naoyuki Kamatani,Tatsuhiko Tsunoda,Konstantinos N. Malizos,Aspasia Tsezou,Antonio Gonzalez,Yusuke Nakamura,Shiro Ikegawa
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0009723
Abstract: Osteoarthritis (OA) is a common disease that has a definite genetic component. Only a few OA susceptibility genes that have definite functional evidence and replication of association have been reported, however. Through a genome-wide association study and a replication using a total of ~4,800 Japanese subjects, we identified two single nucleotide polymorphisms (SNPs) (rs7775228 and rs10947262) associated with susceptibility to knee OA. The two SNPs were in a region containing HLA class II/III genes and their association reached genome-wide significance (combined P = 2.43×10?8 for rs7775228 and 6.73×10?8 for rs10947262). Our results suggest that immunologic mechanism is implicated in the etiology of OA.
Ana Cristina Castro Fontenla Sieira
Engevista , 2009,
Abstract: The present paper discusses aspects related to two different techniques of slope stabilization. The first technique consists of the stabilization through the construction of tires retaining walls. For so much, it will be presented a research project that culminated in the construction of the first experimental wall of tires in Brazil. The determination of the representative parameters of the behavior of tire walls will be presented, together with the main constructive aspects and the mechanical behavior of the wall. The second technique consists of the execution of walls reinforced with geosynthetics. This paper presents aspects related to the determination of resistance parameters in the soil-reinforcement interface and a practical experience related to the execution of a wall reinforced with geotextiles in a dam of solid residues. As main conclusions, to stand out the potential of geosynthetics materials as elements of soil reinforcement, and the use of tires walls as an attractive alternative which associates efficient mechanical performance with low cost, and demand of industrial solid residues.
Towards a Generalized Architecture for the Integration of Tools in LMSs
Jorge Fontenla Gonzalez,Manuel Caeiro Rodriguez,Martin Llamas Nistal
International Journal of Emerging Technologies in Learning (iJET) , 2009, DOI: 10.3991/ijet.v4i0.792
Abstract: In this article we introduce the main components of a generalized architecture to facilitate the integration of tools in LMSs. This proposal tries to improve the reuse possibilities of the tools in e-learning systems. Reusability has been suggested as a key solution to reduce the high costs of the development of educational experiences in e-learning systems. Up to now, reutilization has focused mainly on the educational contents around metadata standards, contents formats, packaging systems, etc. However, educational practices usually involve tools to facilitate the communication, collaboration and work of students and teachers as well. This proposal is part of a wider solution based on the language PoEML, in which not only the possibility of the inclusion of tools in LMSs is considered, but also the management of its utilization.
Consideraciones sobre la utilización de diferentes densidades en el cultivo de papaya (Carica papaya, L.) "Baixinho de Santa Amalia" en islas canarias
Pastor, Ma Cristina Rodriguez;
Revista Brasileira de Fruticultura , 2002, DOI: 10.1590/S0100-29452002000300035
Abstract: the growth of papaya plants under greenhouse conditions has recently become the norm in the canary islands. the use of "baixinho de santa amalia" (a natural mutant of the "sunrise" cultivar), which is a dwarf cultivar flowering early and not high up the plant, is the great interest, above all under these conditions. these phenological characteristic make possible the planting at higher densities than for other cultivars. this study has been carried out to determine the optimal planting density to permit greater production without reducing fruit quality. to this aim the yield, both of hermaphrodite and female plants, has been evaluated through two crop cycles, as well as studying the organoleptic characteristics, degree of carpellody and deformation of the fruits. the results suggest that the highest density provides better plant perfomance as well as higher fruit production and lower percentage of rejected fruit.
Consideraciones sobre la utilización de diferentes densidades en el cultivo de papaya (Carica papaya, L.) "Baixinho de Santa Amalia" en islas canarias
Pastor Ma Cristina Rodriguez
Revista Brasileira de Fruticultura , 2002,
Abstract: El cultivo de papaya en Islas Canarias se ha extendido en los últimos a os bajo condiciones de invernadero. La utilización de cultivares de papaya tipo "Baixinho de Santa Amalia" (mutante natural del cultivar "Sunrise") de porte bajo, emisión de la flor a corta altura y precocidad en la floración, resultan de gran interés sobre todo en esta clase de medios. Estas características fenológicas hacen posible el manejo del cultivo a mayores densidades que las empleadas con otros cultivares. Por lo tanto, se ha planteado este trabajo cuyo objetivo principal es determinar cual es el marco de plantación óptimo, que permita obtener mayores rendimientos sin depreciar la calidad del fruto. Para ello, se ha evaluado la producción tanto de las plantas hermafroditas como de las plantas femeninas durante dos ciclos de cultivo, así como las características organolépticas, grado de carpeloidía y deformación de los frutos. Los resultados indican que la densidad mayor, proporciona mejor comportamiento de las plantas así como mayor producción de frutos y menor porcentaje de fruta desechable.
Artistes espagnols au Salon d’automne de 1920 Artistas espa oles en el Salon d’automne de París, 1920 Spanish artists at the Salon d’automne, Paris, 1920
Cristina Rodriguez?Samaniego
Cahiers de Civilisation Espagnole Contemporaine , 2011, DOI: 10.4000/ccec.2711
Abstract: L’article prétend analyser l’exposition catalane du Salon d’Automne de 1920, en se focalisant sur le r le joué par les artistes participants dans leur contexte culturel à Paris ainsi qu’à Barcelone. L’étude de cet événement permet d’illustrer à la perfection un moment culminant des relations artistiques et culturelles entre la France et l’Espagne, ainsi que de se rapprocher d’une période très intéressante en raison de sa richesse culturelle et de la diversité des manifestations artistiques qui s’y sont produites. El artículo que aquí presentamos pretende abordar las relaciones artísticas y culturales franco-espa olas entorno al a o 1920, cuando un grupo de artistas catalanes fueron invitados a exponer su obra en una sala reservada a dicho fin en el Salon d’Automne de París. Se analizan la idiosincrasia de las prácticas culturales francesas y espa olas – particularmente, catalanas- de la época mencionada, con un interés especial en los puntos de contacto entre ambas, así como en la actividad, evolución y recepción crítica de los artistas espa oles figurativos trabajando en la capital francesa durante las dos primeras décadas del siglo XX. This article wills to analyse the artistic and cultural relationship between France and Spain about 1920, when a group of Catalan artists where invited to exhibit their works in a special room of the Salon d’Automne. The idiosyncrasy of the French and Spanish cultural tendencies will be analysed, and a particular interest will be given the activities, evolution and critical reception of the Spanish figurative artists working I the French capital city during the two first decades of the 20th century.
La prostitución, la trata de mujeres y ni as, y la ley: derechos de las humanas o seguridad del estado?
Marta Fontenla
Mora (Buenos Aires) , 2008,
Implantación y desarrollo de un sistema de gestión ambiental en Ence-Pontevedra
José Buela Fontenla
Revista Galega de Economía , 2002,
Abstract: En el presente trabajo se exponen las distintas fases y etapas que transcurrieron durante el proceso de implantación de un Sistema de Gestión Ambiental (SIGMA) en la fábrica de pasta de papel de ENCE en Pontevedra. Destacan las actividades referentes a la educaciónsensibilización ambiental previa a la propia implantación del sistema, por considerar que ha sido clave para la predisposición del personal ante la instauración de esta herramienta de trabajo que supone un SIGMA.
El proyecto de restauración: documento en el Libro de Fábrica del Monumento
Fontenla San Juan, Concha
Cuadernos de Estudios Gallegos , 1998,
Abstract: Not avalaible No disponible
La restauración arquitectónica en Galicia. Reflexiones
Fontenla San Juan, Concha
Cuadernos de Estudios Gallegos , 1997,
Abstract: Not avalaible No disponible
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