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Search Results: 1 - 10 of 199398 matches for " Concepción Francos Maldonado "
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Lecturas interculturales: Una propuesta para el aula de ELE
Concepción Francos Maldonado
Foro de Profesores de E/LE , 2010,
Abstract: En una sociedad pluricultural y plurilingüe es necesario fomentar el respeto al plurilingüismo, a la diversidad cultural, y potenciar el desarrollo de la conciencia intercultural. Una vía, para ello, son las lecturas multiculturales. Sabemos que adquirir una lengua, materna o no, implica un complejo campo de aspectos que van más allá de lo lingüístico. Por otra parte, es importante tener en cuenta en el aprendizaje de una L2 el bagaje de conocimientos previos del alumnado que aprende. Entre ellos, los conocimientos culturales y las emociones que se implican en el contacto con la nueva lengua y cultura. En el aula, tienen que estar presentes aspectos culturales de la lengua y la cultura meta, pero, también, de las de origen, así como los aspectos afectivos, para que la adquisición de la competencia comunicativa intercultural sea posible.
Una propuesta para el aprendizaje de ELE: tiempo libre e interculturalidad
Concepción Francos Maldonado
Foro de Profesores de E/LE , 2009,
Abstract: En la propuesta que aquí describimos nos centramos en el tiempo de ocio como elemento esencial de socialización y desarrollo personal, y pretendemos que el alumnado participe en las actividades de ocio de la ciudad, a través de las que, además de favorecer la igualdad de oportunidades, la autonomía y las potencialidades individuales, se aprende la lengua y se trabaja la interculturalidad conociendo formas de uso del tiempo libre en la sociedad en la que estamos, informándonos de aspectos lúdicos de diferentes culturas, y también de algunos aspectos curriculares.
Enfermedades de transmisión sexual: estado actual en el caso del virus de la Hepatitis B y C
Concepción García Luján,Aurora Martínez Romero,Jesús Vásquez Arroyo,Aurelio Maldonado Cabrera
Química Viva , 2008,
Abstract: Las enfermedades de transmisión sexual (ETS) son un problema de salud pública en el mundo, especialmente en los países en vías de desarrollo, debido a la infertilidad, discapacidad a corto plazo con consecuencias médicas y psicológicas para miles de hombres, mujeres y ni os. Las consecuencias de las ETS son dramáticas si se tiene en cuenta su contribución potencial a la transmisión del virus VIH. Para tomar un ejemplo de un país con buenas estadísticas: la incidencia de carcinoma hepatocelular (HCC) en los Estados Unidos se duplicó durante los últimos 20 a os y continúa incrementándose rápidamente. Las principales causas de esta enfermedad son las infecciones virales crónicas causadas por los virus de hepatitis B y C. Hay aproximadamente 3,5 millones de americanos infectados de manera crónica con el virus de la hepatitis C (HCV). La mayoría de estos individuos no han sido diagnosticados. Mientras que para el virus de la hepatitis B (HBV) se estima que 1,25 millones de personas están infectados de manera crónica. Con una alta proporción entre los inmigrantes de Asia, Africa del sub-Sahara, y zonas de centro y Sudamérica.
Effect of the CB1 cannabinoid agonist WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference in mice
Carmen Manzanedo, Marta Rodríguez-Arias, Manuel Daza-Losada, Concepción Maldonado, María A Aguilar, José Mi?arro
Behavioral and Brain Functions , 2010, DOI: 10.1186/1744-9081-6-19
Abstract: In the first experiment adolescent mice were initially conditioned with 1.25, 2.5 or 5 mg/kg of MDMA or 0.1 or 0.5 mg/kg of WIN and subsequently with both drugs. Reinstatement of the extinguished preference by priming doses was performed in the groups that showed CPP. In the second experiment, animals were conditioned with 2.5 or 5 mg/kg of MDMA and, after extinction, reinstatement of the preference was induced by 0.5 or 0.1 mg/kg of WIN.A low dose of WIN 55212-2 (0.1 mg/kg) increased the rewarding effects of low doses of MDMA (1.25 mg/kg), although a decrease in the preference induced by MDMA (5 and 2.5 mg/kg) was observed when the dose of WIN 55212-2 was raised (0.5 mg/kg). The CB1 antagonist SR 141716 also increased the rewarding effects of the lowest MDMA dose and did not block the effects of WIN. Animals treated with the highest WIN dose plus a non-neurotoxic dose of MDMA exhibited decreases of striatal DA and serotonin in the cortex. On the other hand, WIN 55212-2-induced CPP was reinstated by priming injections of MDMA, although WIN did not reinstate the MDMA-induced CPP.These results confirm that the cannabinoid system plays a role in the rewarding effects of MDMA and highlights the risks that sporadic drug use can pose in terms of relapse to dependence. Finally, the potential neuroprotective action of cannabinoids is not supported by our data; on the contrary, they are evidence of the potential neurotoxic effect of said drugs when administered with MDMA.Numerous reports indicate that MDMA users consume other psychoactive drugs, among which cannabis is one of the most common. Findings regarding concomitant abuse of MDMA and cannabis are similar in different countries, ranging from between 73% and 100% [for review see [1,2]]. Several studies of the prolonged combined use of MDMA and cannabis have highlighted an association with a variety of psychological problems, including elevated impulsiveness, anxiety and psychotic behavior [3].MDMA is an indirect monoami
The Novelty-Seeking Phenotype Modulates the Long-Lasting Effects of Intermittent Ethanol Administration during Adolescence
Sandra Montagud-Romero, Manuel Daza-Losada, Antonio Vidal-Infer, Concepción Maldonado, María A. Aguilar, Jose Mi?arro, Marta Rodríguez-Arias
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0092576
Abstract: The aim of the present study was to investigate if a novelty-seeking phenotype mediates the long-lasting consequences of intermittent EtOH intoxication during adolescence. The hole board test was employed to classify adolescent mice as High- or Low-Novelty Seekers. Subsequently, animals were administered ethanol (1.25 or 2.5 g/kg) on two consecutive days at 48-h intervals over a 14-day period. Anxiety levels - measured using the elevated plus maze- spontaneous motor activity and social interaction test were studied 3 weeks later. A different set of mice underwent the same procedure, but received only the 2.5 g/kg dose of ethanol. Three weeks later, in order to induce CPP, the same animals were administered 1 or 6 mg/kg of cocaine or 1 or 2.5 mg/kg MDMA. The results revealed a decrease in aggressive behaviors and an anxiolytic profile in HNS mice and longer latency to explore the novel object by LNS mice. Ethanol exposure enhanced the reinforcing effects of cocaine and MDMA in both groups when CPP was induced with a sub-threshold dose of the drugs. The extinguished cocaine-induced CPP (1 and 6 mg/kg) was reinstated after a priming dose in HNS animals only. Our results confirm that intermittent EtOH administration during adolescence induces long-lasting effects that are manifested in adult life, and that there is an association between these effects and the novelty-seeking phenotype.
Outstanding Rhetorical Devices and Textuality in Obama’s Speech in Ghana, Africa  [PDF]
Concepción Hernández-Guerra
Open Journal of Modern Linguistics (OJML) , 2012, DOI: 10.4236/ojml.2012.23013
Abstract: Latest trends in political discursive analysis have shown the importance of the study done from the textual and contextual perspective alike. An oral speech has the property of having been prepared in advance but expressed with some improvisation so characteristics from written and oral texts must be taken into consideration. As a consequence, the structure of the discourse and the personal contribution of the author are seemingly relevant. The oral speech analyzed here was expressed in Ghana, Africa by President Barack Obama in 2009. Given the circumstances of Obama’s African origin and of visiting the country as the President of the United States, the elements that reveal the personal attitude comprise an extra interest. The aim of this paper is to analyze the speech from a discursive viewpoint in order to describe the textual and intertextual functions.
Vigorous, but differential mononuclear cell response of cirrhotic patients to bacterial ligands
Varenka J Barbero-Becerra, María Concepción Gutiérrez-Ruiz, Carmen Maldonado-Bernal, Félix I Téllez-Avila, Roberto Alfaro-Lara, Florencia Vargas-Vorácková
World Journal of Gastroenterology , 2011,
Abstract: AIM: To study the role of gram-positive and gram-negative bacteria in the pathogenesis of liver injury, specifically the activation of inflammatory mediators.METHODS: Peripheral blood mononuclear cells of 20 out-patients were studied, 10 of them with cirrhosis. Peripheral blood mononuclear cells were isolated and exposed to lipopolysaccharide or lipoteichoic acid. CD14, Toll-like receptor 2 and 4 expression was determined by flow cytometry, and tumor necrosis factor (TNF) α, interleukin (IL)-1β, IL-6, IL-12 and IL-10 secretion in supernatants was determined by ELISA.RESULTS: Higher CD14, Toll-like receptor 2 and 4 expression was observed in peripheral blood mononuclear cells from cirrhotic patients, (P < 0.01, P < 0.006, P < 0.111) respectively. Lipopolysaccharide and lipoteichoic acid induced a further increase in CD14 expression (P < 0.111 lipopolysaccharide, P < 0.013 lipoteichoic acid), and a decrease in Toll-like receptor 2 (P < 0.008 lipopolysaccharide, P < 0.008 lipoteichoic acid) and Toll-like receptor 4 (P < 0.008 lipopolysaccharide, P < 0.028 lipoteichoic acid) expression. With the exception of TNFα, absolute cytokine secretion of peripheral blood mononuclear cells was lower in cirrhotic patients under non-exposure conditions (P < 0.070 IL-6, P < 0.009 IL-1β, P < 0.022 IL-12). Once exposed to lipopolysaccharide or lipoteichoic acid, absolute cytokine secretion of peripheral blood mononuclear cells was similar in cirrhotic and non-cirrhotic patients, determining a more vigorous response in the former (P < 0.005 TNFα, IL-1β, IL-6, IL-2 and IL-10 lipopolysaccharide; P < 0.037 TNFα; P < 0.006 IL-1β; P < 0.005 IL-6; P < 0.007 IL-12; P < 0.014 IL-10 lipoteichoic acid). Response of peripheral blood mononuclear cells was more intense after lipopolysaccharide than after lipoteichoic acid exposure.CONCLUSION: Peripheral blood mononuclear cells of cirrhotic patients are able to respond to a sudden bacterial ligand exposure, particularly lipopolysaccharide, suggesting that immune regulation mechanisms are still present.
The Marian Illustrations of the Legend of Montserrat
Alarcón, Concepción
Revista de Dialectología y Tradiciones Populares , 2008,
Abstract: The books telling the story of Montserrat used to contain illustrative engravings. Montserrat presents us with a special case, because this monastery holds an uninterrupted record of illustrated texts or of texts with engraved images from the miniatures of the Llibre Vermell and the first fruits of the printing press to the 19th century. Admittedly, in the 16th, 17th and 18th centuries the books exhibit the engravings on the cover or within the first sheets; it is only in the 19th century that illustrations appear inserted in the text so as to make the story more agreeable. The images intensify the value of texts, since illustrations can help us understand the written word and may suggest other readings of the corresponding passages, clearer and more precise. Illustrations in the books on the history of a monastery are but a part of a larger set of ideas, projects and self-service which the Church aims at the reader. Furthermore, the iconographic models of the Virgin Mary and the Mountain are of great interest for the history of engraving and of the Catalan and Spanish devotions. Los libros en que se contaba la historia de Montserrat contenían estampas que los ilustraban. Montserrat es un caso inusual, porque posee un registro ininterrumpido de textos ilustrados o acompa ados con imágenes grabadas, desde el Llibre Vermell y los primeros momentos de la imprenta hasta el siglo XIX. Bien es cierto que en los libros de los siglos XVI, XVII y XVIII sólo se colocan los grabados en la portada o en las primeras hojas; Hasta el siglo XIX no encontramos un tipo de ilustración insertada en el interior del texto amenizando la historia. Las imágenes intensifican el valor de los textos, porque nos ayudan a comprenderlos y a la vez sugieren nuevas lecturas, más precisas y claras. Las ilustraciones de los libros de historia de un santuario forman parte de todo un enjambre de ideas, proyectos y propaganda que la Iglesia quiere transmitir al lector. Por otro lado los modelos iconográficos de María y la monta a son de gran interés para la historia del grabado y de la devoción catalana y espa ola.
Software Project Visualization Using Task Oriented Metaphors  [PDF]
Amaia Aguirregoitia, José Javier Dolado Cosín, Concepción Presedo
Journal of Software Engineering and Applications (JSEA) , 2010, DOI: 10.4236/jsea.2010.311119
Abstract: This paper presents T-Cube and MetroMap, two new graphical representation models for controlling and managing the processes of software project development. They both use metaphors and visual representation techniques to address typical project management tasks. T-Cube uses a metaphor with the Rubik-Cube whereas MetroMap uses a metaphor with a metro map. The tools have been tested on real project data and a qualitative assessment shows the results of testing the visualizations with users attempting several information retrieval tasks. The utility of the tools has been positively evaluated and the article demonstrates the possibilities of visual approaches in project management.
Measurement of Transcutaneous Bilirubin with Bilicheck as a Jaundice Screening Method in Neonates in Pediatric Emergency Departments  [PDF]
Concepción Míguez, Mercedes Fari?as Salto, Rafael Mara?ón
Open Journal of Pediatrics (OJPed) , 2015, DOI: 10.4236/ojped.2015.53037
Abstract: Objectives: To study the reliability of a transcutaneous bilirubinometer (Bilicheck) to determine bilirubin levels in neonates consulting for jaundice in a Paediatric Emergency Department (ED), and to evaluate its usefulness as a screening method. Methods: Prospective observational study realized between June of 2005 and December of2005 inneonates consulting at a paediatric emergency department for jaundice, in whom we realized both transcutaneous and total serum bilirubin measurements (TcB and TSB). We collected demographic variables, analytical variables (serum and transcutaneous bilirubin levels), length of stay in the ED, and need for treatment. Results: 66 children were included aged 2 to 31 days (81% of the sample were 2 to 7 days old). There was a close and statistically significant correlation between TcB and TSB (r = 0.81, p < 0.001). The area under the ROC curve was of 0.90, allowing detecting newborns with jaundice susceptible of treatment with TcB levels ≥ 13 mg/dL (sensitivity 92%, specificity 63, 5%, a positive predictive value 39% and a negative predictive value 97%). The number of venous punctures could be reduced in 50%. The medium stay in the ED was of 2 hours when performing serum measurements. Conclusions: A linear correlation exists between TcB-TSB. TcB measurement cannot replace that of TsB, however it could be used as a screening method in an ED to determine which neonates need confirmation by TsB measurement. The use of transcutaneous bilirubinometer would reduce both the number of painful interventions in neonates and the medium length of stay in ED, consequently reducing iatrogenesis.
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