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Search Results: 1 - 10 of 493 matches for " Comer GM "
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Acute anterior uveitis following intravitreal bevacizumab but not subsequent ranibizumab
Antonopoulos C, Stem M, Comer GM
Clinical Ophthalmology , 2011, DOI: http://dx.doi.org/10.2147/OPTH.S26880
Abstract: cute anterior uveitis following intravitreal bevacizumab but not subsequent ranibizumab Case report (2697) Total Article Views Authors: Antonopoulos C, Stem M, Comer GM Published Date November 2011 Volume 2011:5 Pages 1659 - 1662 DOI: http://dx.doi.org/10.2147/OPTH.S26880 Christina Antonopoulos1, Maxwell Stem2, Grant M Comer2 1Department of Ophthalmology, Boston University, Boston, MA, USA; 2WK Kellogg Eye Center, Department of Ophthalmology, University of Michigan, Ann Arbor, MI, USA Purpose: Previous reports have identified noninfectious uveitis as a potential sequela following both intravitreal bevacizumab and ranibizumab injections. We present two unique cases of acute anterior uveitis following intravitreal bevacizumab that did not occur with subsequent ranibizumab injections. Methods: Case report. Conclusion: These cases may reflect differences in the etiology of anterior uveitis following intravitreal bevacizumab and ranibizumab. Given these differences, it may be reasonable to offer ranibizumab to patients who have experienced presumed bevacizumab-induced anterior uveitis.
Successful salvage therapy of Fusarium endophthalmitis secondary to keratitis: an interventional case series
Comer GM, Stem MS, Saxe SJ
Clinical Ophthalmology , 2012, DOI: http://dx.doi.org/10.2147/OPTH.S31652
Abstract: ccessful salvage therapy of Fusarium endophthalmitis secondary to keratitis: an interventional case series Case Series (2130) Total Article Views Authors: Comer GM, Stem MS, Saxe SJ Supplementary intraoperative video capturing abscess removal Views: 64 Published Date May 2012 Volume 2012:6 Pages 721 - 726 DOI: http://dx.doi.org/10.2147/OPTH.S31652 Received: 10 March 2012 Accepted: 23 March 2012 Published: 09 May 2012 Grant M Comer, Maxwell S Stem, Stephen J Saxe University of Michigan, Department of Ophthalmology and Visual Sciences, Ann Arbor, MI, USA Purpose: To describe a combination of treatment modalities used for the successful eradication of Fusarium endophthalmitis. Design: Interventional case series. Participants: Three consecutive patients with keratitis-associated Fusarium endophthalmitis. Methods: After failure of traditional management options, a combination of intravitreal and long-term, high-dose systemic voriconazole, topical antifungal medications, and surgical intervention, with penetrating keratoplasty, lensectomy, and endoscopic-guided pars plana vitrectomy, was administered to each patient. Results: All three cases achieved full resolution of the infection, with a final Snellen visual acuity score of 20/50 to 20/70. Conclusions: An aggressive combination of therapeutic modalities, including the removal of subiris abscesses, might be needed for the successful resolution of Fusarium endophthalmitis.
Acute anterior uveitis following intravitreal bevacizumab but not subsequent ranibizumab
Antonopoulos C,Stem M,Comer GM
Clinical Ophthalmology , 2011,
Abstract: Christina Antonopoulos1, Maxwell Stem2, Grant M Comer21Department of Ophthalmology, Boston University, Boston, MA, USA; 2WK Kellogg Eye Center, Department of Ophthalmology, University of Michigan, Ann Arbor, MI, USAPurpose: Previous reports have identified noninfectious uveitis as a potential sequela following both intravitreal bevacizumab and ranibizumab injections. We present two unique cases of acute anterior uveitis following intravitreal bevacizumab that did not occur with subsequent ranibizumab injections.Methods: Case report.Conclusion: These cases may reflect differences in the etiology of anterior uveitis following intravitreal bevacizumab and ranibizumab. Given these differences, it may be reasonable to offer ranibizumab to patients who have experienced presumed bevacizumab-induced anterior uveitis.Keywords: adverse effect, age-related macular degeneration, anterior uveitis, bevacizumab, ranibizumab, uveitis
Successful salvage therapy of Fusarium endophthalmitis secondary to keratitis: an interventional case series
Comer GM,Stem MS,Saxe SJ
Clinical Ophthalmology , 2012,
Abstract: Grant M Comer, Maxwell S Stem, Stephen J SaxeUniversity of Michigan, Department of Ophthalmology and Visual Sciences, Ann Arbor, MI, USAPurpose: To describe a combination of treatment modalities used for the successful eradication of Fusarium endophthalmitis.Design: Interventional case series.Participants: Three consecutive patients with keratitis-associated Fusarium endophthalmitis.Methods: After failure of traditional management options, a combination of intravitreal and long-term, high-dose systemic voriconazole, topical antifungal medications, and surgical intervention, with penetrating keratoplasty, lensectomy, and endoscopic-guided pars plana vitrectomy, was administered to each patient.Results: All three cases achieved full resolution of the infection, with a final Snellen visual acuity score of 20/50 to 20/70.Conclusions: An aggressive combination of therapeutic modalities, including the removal of subiris abscesses, might be needed for the successful resolution of Fusarium endophthalmitis.Keywords: endophthalmitis, fungal, Fusarium, keratitis, keratoplasty, voriconazole
Zener Zap Anti-Fuse Trim in VLSI Circuits
Donald T. Comer
VLSI Design , 1996, DOI: 10.1155/1996/23706
Abstract:
Lattice Boltzmann simulations of three-dimensional single droplet deformation and breakup under simple shear flow
Haowen Xi,Comer Duncan
Physics , 1998, DOI: 10.1103/PhysRevE.59.3022
Abstract: We present three-dimensional numerical simulations of the classical Taylor experiment on droplet deformation within a shear flow. We have used the promising Lattice-Boltzmann method numerical scheme to simulate single droplet deformation and breakup under simple shear flow. We first compute the deformation of the droplet and find excellent agreement with the theoretical prediction. We have used the same method to simulate the shear and breakup for larger values of the shear rate. We find that the Lattice Boltzmann method used in conjunction with the interface force model of Shan and Chen results in an excellent treatment of the entire process from small deformation to breakup into multiple droplets. Our results could be extended to study the rheology of dispersed droplets and the dynamics of droplet breakup and coalescence in shear flow.
3+1 Approach to the Long Wavelength Iteration Scheme
G. L. Comer
Physics , 2005, DOI: 10.1088/0264-9381/14/2/014
Abstract: Large-scale inhomogeneities and anisotropies are modeled using the Long Wavelength Iteration Scheme. In this scheme solutions are obtained as expansions in spatial gradients, which are taken to be small. It is shown that the choice of foliation for spacetime can make the iteration scheme more effective in two respects: (i) the shift vector can be chosen so as to dilute the effect of anisotropy on the late-time value of the extrinsic curvature of the spacelike hypersurfaces of the foliation; and (ii) pure gauge solutions present in a similar calculation using the synchronous gauge vanish when the spacelike hypersurfaces have extrinsic curvature with constant trace. We furthermore verify the main conclusion of the synchronous gauge calculation which is large-scale inhomogeneity decays if the matter--considered to be that of a perfect-fluid with a barotropic equation of state--violates the strong-energy condition. Finally, we obtain the solution for the lapse function and discuss its late-time behaviour. It is found that the lapse function is well-behaved when the matter violates the strong energy condition.
A note on the kinematics of dislocations in crystals
Jeffrey Comer,Ruslan Sharipov
Physics , 2004,
Abstract: A part of the theory of dislocations in crystals is revised with the aim to fit it into the framework of the nonlinear theory of plasticity initially designed for amorphous glassy materials.
Matters of Gravity, The Newsletter of the Topical Group in Gravitation of the American Physical Society, Volume 31, Winter 2008
David Garfinkle,Greg Comer
Physics , 2008,
Abstract: GGR News: GGR program at the APS meeting in St. Louis we hear that... by David Garfinkle 100 years ago, by David Garfinkle Research Briefs: The Torsion Pendulum's Contribution to Dark Energy, by Bill Hamilton Conference Reports: 10th Capra Meeting on Radiation Reaction, by Carlos Sopuerta Quantum Gravity in the Southern Cone IV, by Rafael A. Porto
Do Neutron Star Gravitational Waves Carry Superfluid Imprints?
G. L. Comer
Physics , 2002, DOI: 10.1023/A:1022322801696
Abstract: Isolated neutron stars undergoing non-radial oscillations are expected to emit gravitational waves in the kilohertz frequency range. To date, radio astronomers have located about 1,300 pulsars, and can estimate that there are about 2 times 10^8 neutron stars in the galaxy. Many of these are surely old and cold enough that their interiors will contain matter in the superfluid or superconducting state. In fact, the so-called glitch phenomenon in pulsars (a sudden spin-up of the pulsar's crust) is best described by assuming the presence of superfluid neutrons and superconducting protons in the inner crusts and cores of the pulsars. Recently there has been much progress on modelling the dynamics of superfluid neutron stars in both the Newtonian and general relativistic regimes. We will discuss some of the main results of this recent work, perhaps the most important being that superfluidity should affect the gravitational waves from neutron stars (emitted, for instance, during a glitch) by modifying both the rotational properties of the background star and the modes of oscillation of the perturbed configuration. Finally, we present an analysis of the so-called zero-frequency subspace (i.e. the space of time-independent perturbations) and determine that it is spanned by two sets of polar (or spheroidal) and two sets of axial (or toroidal) degenerate perturbations for the general relativistic system. As in the Newtonian case, the polar perturbations are the g-modes which are missing from the pulsation spectrum of a non-rotating configuration, and the axial perturbations should lead to two sets of r-modes when the degeneracy of the frequencies is broken by having the background rotate.
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