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Search Results: 1 - 10 of 830 matches for " Clyde; Fajardo "
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Were the First Europeans Pale or Dark Skinned?  [PDF]
Clyde Winters
Advances in Anthropology (AA) , 2014, DOI: 10.4236/aa.2014.43016
Abstract:

This is an overview of the Out of Africa (OoA) settlement of Europe during the Aurignacian period. Klyosov claims that the first Europeans were fair (pale) skin, and Neanderthal who never lived in Africa. Archaeological evidence indicated that Neanderthals originated in Africa and between 139 kya and 125 kya the Neanderthals migrated back into Africa and spread from Morocco to East Africa. The archaeological, anthropological and genetic evidence indicated that the first Europeans were dark skin Sub-Saharan Africans who carried mtDNA haplogroup N and Y-chromosome C6 into Europe.

Determinación de residuos de deoxicolato de sodio en formulaciones vacunales por cromatografía electrocinética micelar
Yaima Merchán,Silvia Lucangioli,Clyde Carducci,Esther María Fajardo
Vaccimonitor , 2011,
Abstract: El deoxicolato de sodio (DCNa) es el surfactante por excelencia empleado en la industria biofarmacéutica para la solubilización de vesículas de membrana externa. Es bien conocida la importancia que reviste el control de este metabolito en materiales biológicos, debido a su alta toxicidad para el organismo humano. Para demostrar la presencia de bajas concentraciones de este metabolito en formulaciones vacunales es necesario el empleo de una metodología altamente selectiva, sensible, específica y reproducible. En el presente reporte se utilizó la cromatografía electrocinética micelar (MEKC) en un analizador capilar de iones (Water corp. Milford MA), con una detección a 185 nm, con lámpara de mercurio. Se empleó un capilar de sílica fundida (Waters Corp. Milford MA;se evaluó la pureza de dos lotes de deoxicolato de sodio y se analizaron 15 muestras de vesículas purificadas,ingrediente farmacéutico activo de formulaciones vacunales. Los datos fueron registrados y procesados con el software MillenniumTM (Waters Corp. Milford MA). Se determinó que los lotes de deoxicolato de sodio contenían 1,19% y 0,44% de ácido cólico contaminante y que el 93% de las muestras de vesículas purificadas tenían de 0 a 2,44 μg DCNa/100 μg de proteína. Los resultados obtenidos por MEKC fueron comparados con una modificaciónde una prueba cinética empleada para determinar ácidos biliares en sangre (Merckotest). El sistema MEKC mostró mejores resultados con respecto al Merkotest.
Determinación de residuos de deoxicolato de sodio en formulaciones vacunales por cromatografía electrocinética micelar
Merchán,Yaima; Lucangioli,Silvia; Carducci,Clyde; Fajardo,Esther María; Rico,Jeannete; Tamayo,Yolexis; Delgado,Ileana;
Vaccimonitor , 2011,
Abstract: the sodium deoxycholate (dcna) source is the surfactant used in the biopharmaceutical industry for the solubilization of outer membrane vesicles. it is well known the importance of control of this metabolite in biological materials due to its high toxicity for humans. to demonstrate significant small variations of this metabolite in vaccine formulations it is necessary to use a methodology highly selective, sensitive, specific and reproducible. in this report we used the micellar electrokinetic chromatography (mekc) in a capillary ion analyzer (water corp. milford ma) detection at 185 nm mercury lamp. it employed a fused silica capillary uncoated (waters corp. milford ma). we assessed the purity of 2 lots of sodium deoxycholate and analyzed 15 samples of purified vesicles active pharmaceutical ingredient vaccine formulations. data were recorded and processed with software millennium tm (waters corp. milford ma). it was found that lots of sodium deoxycholate containing 1.19 and 0.44% cholic acid and contaminate that 93% of the purified vesicles samples were from 0 to 2.44 mg protein dcna/100 μg. meck's results were compared with a kinetic test used to determine bile acids in blood (merckotest). meck system showed better results regarding the merkotest.
Gatifloxacin Ophthalmic Solution for Treatment of Bacterial Conjunctivitis: Safety, Efficacy and Patient Perspective
Clyde Schultz
Ophthalmology and Eye Diseases , 2012, DOI: 10.4137/OED.S7383
Abstract: Gatifloxacin is a fourth generation fluroquinolone antibiotic that has been prescribed for systemic use. However, the drug which was developed by Kyorin (Japan) was linked to toxic reactions and death and was banned in the United States and Canada for use as an oral dosage form. It continues to be used as a topical application for ophthalmic conditions as the systemic toxicity seen when taking the drug orally has not been observed with ophthalmic use. The available data indicate that ocular use of gatifloxacin is safe, and effective against a broad spectrum of bacteria, including intracellular bacteria and anaerobes.
Tafluprost for the Reduction of Interocular Pressure in Open Angle Glaucoma and Ocular Hypertension
Clyde Schultz
Ophthalmology and Eye Diseases , 2012, DOI: 10.4137/OED.S4253
Abstract: Tafluprost is an FP receptor antagonist that has been shown in clinical studies in Europe and Japan to be extremely useful in treating elevated intraocular pressure and glaucoma. The drug is well tolerated and appears to be at least equal in effectiveness and perhaps superior to other protanoids for routine use comparison to be superior to other treatments for the elevated IOP as the side effects and other related symptomology appear to be less, while maintaining a level of pressure control for prolonged periods.
Book Review: Newspeak in the 21st Century
Clyde Sanger
Global Media Journal : Canadian Edition , 2010,
Abstract:
Voclosporin as a Treatment for Noninfectious Uveitis
Clyde Schultz
Ophthalmology and Eye Diseases , 2013,
Abstract:
Gatifloxacin Ophthalmic Solution for Treatment of Bacterial Conjunctivitis: Safety, Efficacy and Patient Perspective
Clyde Schultz
Ophthalmology and Eye Diseases , 2012,
Abstract:
Tafluprost for the Reduction of Interocular Pressure in Open Angle Glaucoma and Ocular Hypertension
Clyde Schultz
Ophthalmology and Eye Diseases , 2011,
Abstract:
The style of academic e-mails and conventional letters: contrastive analysis of four conversational routines
Clyde Ancarno
Ibérica , 2005,
Abstract: This paper presents the results of a corpus-based study which investigates the genre of academic email and more specifically its pragmatic dimension. Four conversational routines (thank yous, apologies, requests, offers) are analysed and compared in two channels: academic e-mails and conventional print letters. In addition, data from both native and non-native speakers of English is considered, which sheds light on some of the differences found in the academic e-mail writing of learners of English. The findings indicate that academic e-mail is a relatively formal type of correspondence which is still largely influenced, as is to be expected, by the genre of the academic letter, and that as a genre, academic e-mail is in the process of formation or semi-formation. Finally, native speakers of English are found to be more informal than non-native speakers of English in academic e-mails.
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