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Search Results: 1 - 10 of 2004 matches for " Clement Kent "
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A Model-Based Analysis of Chemical and Temporal Patterns of Cuticular Hydrocarbons in Male Drosophila melanogaster
Clement Kent, Reza Azanchi, Ben Smith, Adrienne Chu, Joel Levine
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000962
Abstract: Drosophila Cuticular Hydrocarbons (CH) influence courtship behaviour, mating, aggregation, oviposition, and resistance to desiccation. We measured levels of 24 different CH compounds of individual male D. melanogaster hourly under a variety of environmental (LD/DD) conditions. Using a model-based analysis of CH variation, we developed an improved normalization method for CH data, and show that CH compounds have reproducible cyclic within-day temporal patterns of expression which differ between LD and DD conditions. Multivariate clustering of expression patterns identified 5 clusters of co-expressed compounds with common chemical characteristics. Turnover rate estimates suggest CH production may be a significant metabolic cost. Male cuticular hydrocarbon expression is a dynamic trait influenced by light and time of day; since abundant hydrocarbons affect male sexual behavior, males may present different pheromonal profiles at different times and under different conditions.
The Drosophila foraging Gene Mediates Adult Plasticity and Gene–Environment Interactions in Behaviour, Metabolites, and Gene Expression in Response to Food Deprivation
Clement F. Kent,Tim Daskalchuk,Lisa Cook,Marla B. Sokolowski ,Ralph J. Greenspan
PLOS Genetics , 2009, DOI: 10.1371/journal.pgen.1000609
Abstract: Nutrition is known to interact with genotype in human metabolic syndromes, obesity, and diabetes, and also in Drosophila metabolism. Plasticity in metabolic responses, such as changes in body fat or blood sugar in response to changes in dietary alterations, may also be affected by genotype. Here we show that variants of the foraging (for) gene in Drosophila melanogaster affect the response to food deprivation in a large suite of adult phenotypes by measuring gene by environment interactions (GEI) in a suite of food-related traits. for affects body fat, carbohydrates, food-leaving behavior, metabolite, and gene expression levels in response to food deprivation. This results in broad patterns of metabolic, genomic, and behavioral gene by environment interactions (GEI), in part by interaction with the insulin signaling pathway. Our results show that a single gene that varies in nature can have far reaching effects on behavior and metabolism by acting through multiple other genes and pathways.
Natural Variation in the Thermotolerance of Neural Function and Behavior due to a cGMP-Dependent Protein Kinase
Ken Dawson-Scully, Gary A. B. Armstrong, Clement Kent, R. Meldrum Robertson, Marla B. Sokolowski
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000773
Abstract: Although it is acknowledged that genetic variation contributes to individual differences in thermotolerance, the specific genes and pathways involved and how they are modulated by the environment remain poorly understood. We link natural variation in the thermotolerance of neural function and behavior in Drosophila melanogaster to the foraging gene (for, which encodes a cGMP-dependent protein kinase (PKG)) as well as to its downstream target, protein phosphatase 2A (PP2A). Genetic and pharmacological manipulations revealed that reduced PKG (or PP2A) activity caused increased thermotolerance of synaptic transmission at the larval neuromuscular junction. Like synaptic transmission, feeding movements were preserved at higher temperatures in larvae with lower PKG levels. In a comparative assay, pharmacological manipulations altering thermotolerance in a central circuit of Locusta migratoria demonstrated conservation of this neuroprotective pathway. In this circuit, either the inhibition of PKG or PP2A induced robust thermotolerance of neural function. We suggest that PKG and therefore the polymorphism associated with the allelic variation in for may provide populations with natural variation in heat stress tolerance. for's function in behavior is conserved across most organisms, including ants, bees, nematodes, and mammals. PKG's role in thermotolerance may also apply to these and other species. Natural variation in thermotolerance arising from genes involved in the PKG pathway could impact the evolution of thermotolerance in natural populations.
Ito’s Formula for the Discrete-Time Quantum Walk in Two Dimensions  [PDF]
Clement Ampadu
Journal of Quantum Information Science (JQIS) , 2012, DOI: 10.4236/jqis.2012.22008
Abstract: Following Konno [1], it is natural to ask: What is the Ito’s formula for the discrete time quantum walk on a graph different than Z, the set of integers? In this paper we answer the question for the discrete time quantum walk on Z2, the square lattice.
On Some Questions of C. Ampadu Associated with the Quantum Random Walk  [PDF]
Clement Ampadu
Applied Mathematics (AM) , 2014, DOI: 10.4236/am.2014.519291
Abstract: We review (not exhaustively) the quantum random walk on the line in various settings, and propose some questions that we believe have not been tackled in the literature. In a sense, this article invites the readers (beginner, intermediate, or advanced), to explore the beautiful area of quantum random walks.
Metaphoric Topicality in Femi Osofisan’s Drama  [PDF]
Clement O. Ajidahun
Advances in Literary Study (ALS) , 2013, DOI: 10.4236/als.2013.11001
Abstract: This paper examines the functional and the significant role of metaphors in literary works. It discusses the centrality of metaphors as a dominant literary device consciously deployed by Femi Osofisan to project the theme of oppression, dehumanization, social injustice and poverty in his plays. The paper focuses on the use of animal and predatory metaphors in Osofisan’s plays to launch an offensive literary attack on the rich and the ruling elite in the society who use their privileged positions to brazenly oppress and brutalize the poor and the downtrodden. The paper, on the other hand, examines the appropriate use of animal metaphors to enlighten and educate the poor on their precarious condition as preys in the hands of the carnivorous ruling class. Finally, the paper discusses the settings and the titles of Osofisan’s plays, the quest motif and the traditional modes as metaphors for oppression.
Bible Interpretation, Evangelization and Faith: Nigerian Context  [PDF]
Clement I. Osunwokeh
Open Journal of Philosophy (OJPP) , 2014, DOI: 10.4236/ojpp.2014.42026
Abstract:

In Christianity evangelization entails bringing the Good News of Jesus Christ into all the strata of humanity from within and making it new. Evangelization efforts in Nigeria have been going on for more than a century. Indeed it has made a noticeable inroad of growth. The evidence is seen. Thunderous sounds are heard from all corners of villages and cities, of Christian church activities; series of strategies are explored by multitude of Christian denominations aimed at “packaging and selling out” one’s denomination to attract more adherents; imposing and well architectural-designed structures of Christian places of worship are seen in many cities. Yet in the same society, all forms of atrocities and abominations of man’s inhumanity to man, lack of basic Christian virtues of honesty, justice, and respect for sacredness of human life are witnessed. In the light of the foregoing, this paper seeks both to presume the general shallowness of Christian faith in Nigeria and to blame it to flaw in the understanding of the Bible as a Christian text. It critically analyzes the three Christian concepts: Bible interpretation, evangelization and faith, exposing their interrelatedness and the challenges posed by such reality to an authentic Christian living.

3D Mobile Augmented Reality Interface for Laboratory Experiments  [PDF]
Clement Onime, Olatunde Abiona
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2016, DOI: 10.4236/ijcns.2016.94006
Abstract: In fields such as science and engineering, virtual environment is commonly used to provide replacements for practical hands-on laboratories. Sometimes, these environments take the form of a remote interface to the physical laboratory apparatus and at other times, in the form of a complete software implementation that simulates the laboratory apparatus. In this paper, we report on the use of a semi-immersive 3D mobile Augmented Reality (mAR) interface and limited simulations as a replacement for practical hands-on laboratories in science and engineering. The 3D-mAR based interfaces implementations for three different experiments (from micro-electronics, power and communications engineering) are presented; the discovered limitations are discussed along with the results of an evaluation by science and engineering students from two different institutions and plans for future work.
The Impact of Commodity Prices, Interest Rate and Exchange Rate on Stock Market Performance: Evidence from Zambia  [PDF]
Nsama Musawa, Clement Mwaanga
Journal of Financial Risk Management (JFRM) , 2017, DOI: 10.4236/jfrm.2017.63022
Abstract: In 2016, the performance of Capital markets in Africa experienced a downward trend. Notable among them were Zambia, Ghana and Nigeria (http://www.african-markets.com/). The Lusaka Securities Exchange (LuSE) share price index was the worst performer year-to-date, down 26.83% in local currency. Among the contributing factors cited were commodity prices as the country relies on copper for more than 70% of its export revenue and had therefore suffered from commodity prices plunged which led to weakened currencies and widened budget shortfalls (http://www.african-markets.com/). Although the contributing factors are known, their impact on the Zambian stock market is not known. This study was an attempt to establish the impact of commodity prices and macroeconomic factors on the stock market returns. Like in similar studies, Nordin et al. (2014) and Alam & Uddin (2009), we used Auto regression Distribution Lag and Cointegration analysis and the Vector Error Correction model on the variables (stock price index, copper price, oil price, interest rates, and exchange rates) for the period 2004-2016. The findings of the study revealed Interest rates, exchange rates, copper and Oil price jointly have the long and short Run impact on the Lusaka Stock Market, but individually, only interest rates and copper prices had a significant long term impact on the stock market, but in the short run only Copper and Exchange rates had an immediate impact on the stock market. One important policy implication of this study is that it will alert the authorities and the investors on the impact of commodity prices, interest rate, and the exchange rate on the Lusaka Securities Exchange stock market performance.
The Impact of Pension Funds’ Investments on the Capital Market—The Case of Lusaka Securities Exchange  [PDF]
Nsama Musawa, Clement Mwaanga
American Journal of Industrial and Business Management (AJIBM) , 2017, DOI: 10.4236/ajibm.2017.710080
Abstract: The Lusaka Securities exchange (LuSE) is one of the developing stock markets in Africa. As of 2015 it had only 22 listed companies with the market capitalization of about 5849 million dollars. There are a number of sectors that contribute to the growth of the stock market in Zambia. This study focused on the insurance sector, the pension funds mobilized contributions from the working population and invested in various assets among them is equity. According to the pension scheme investment guidelines (2011), pension funds are mandated to invest not less than 5% but not more than 70% of their total investment in equity. Hence, one would expect pension funds to have a good effect on the Zambian capital market. However the impact cannot be conclusive without undertaking a study to assess the effect of pension funds and capital market. Therefore, this study was an attempt to investigate the long run effect of pension fund’s investment on the Lusaka securities exchange performance. The study used quarterly data for the period ranging from January 2009 to December 2015, and employed the cointegration and Vector Error Correction; the results prove the existence of long run relationships between the pension funds and the market capitalization. This relationship implies that if pension funds are encouraged to invest more in equity, it will contribute to the growth of capital market, hence developing. Recommendations have been made to policy markers on how they can use the sector to improve the performance of the capital market.
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