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Search Results: 1 - 10 of 347978 matches for " Claudio; López E "
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CONSTRUCCIóN Y VALIDACIóN DE UN CUESTIONARIO PARA MEDIR CONDUCTAS Y HáBITOS ALIMENTARIOS EN USUARIOS DE LA ATENCIóN PRIMARIA DE SALUD
Pino V,José Luis; Díaz H,Claudio; López E,Miguel ángel;
Revista chilena de nutrición , 2011, DOI: 10.4067/S0717-75182011000100005
Abstract: to identify behaviors and habits of the population is critical to establish appropriate strategies and tools to promote changes inappropriate practices. the aim of this study was to develop a reliable tool to quantify and determine eating habits both in individuals and in the population. based on the survey validated by pardo in 2004, a group of students of 3rd year of nutrition and dietetics took a survey of 44 items, which was applied to a sample of 402 subjects (220 women and 180 males) whose average age was 30.2 ± 24.7years. the questionnaire showed acceptable reliability (α=0.792), establishing 11 dimensions with 38 questions. females showed a significantly higher average total score compared to males (p<0.001). in conclusion, implementation and validation of the questionnaire allows us to contribute a low-cost tool to know the intimate aspects of the behavior ofpeople attending public health centers.
CONSTRUCCIóN Y VALIDACIóN DE UN CUESTIONARIO PARA MEDIR CONDUCTAS Y HáBITOS ALIMENTARIOS EN USUARIOS DE LA ATENCIóN PRIMARIA DE SALUD DEVELOPMENT OF A QUESTIONNAIRE TO MEASURE BEHAVIOR AND FOOD HABITS IN USERS OF PRIMARY HEALTH CARE
José Luis Pino V,Claudio Díaz H,Miguel ángel López E
Revista Chilena de Nutricíon , 2011,
Abstract: Identificar las conductas y hábitos de la población es fundamental para establecer las estrategias y herramientas pertinentes para promover el cambio de las prácticas inadecuadas. El objetivo de este estudio es elaborar una herramienta confiable que permita cuantificar y determinar los hábitos alimentarios tanto individuales como poblacionales. En base a la encuesta validada por Pardo (2004), un grupo de estudiantes de 3° a o de Nutrición y Dietética elaboró una encuesta de 48 ítems, la cual se aplicó a una muestra de 402 personas de todos los grupos etarios (220 mujeres y 180 varones), cuya edad promedio fue de 30,24 ± 24,75 a os. El cuestionario revela una confiabilidad aceptable (α=0,792), estableciéndose 11 dimensiones con 38 preguntas. Las mujeres presentaron un puntaje total promedio significativamente superior en comparación a los varones (p<0,001). En conclusión, la aplicación y validación del cuestionario nos permite contribuir con una herramienta de bajo costo que permita conocer aspectos más íntimos de las conductas alimentarias que forman parte de los hábitos de personas que asisten a centros de salud públicos. To identify behaviors and habits of the population is critical to establish appropriate strategies and tools to promote changes inappropriate practices. The aim of this study was to develop a reliable tool to quantify and determine eating habits both in individuals and in the population. Based on the survey validated by Pardo in 2004, a group of students of 3rd year of Nutrition and Dietetics took a survey of 44 items, which was applied to a sample of 402 subjects (220 women and 180 males) whose average age was 30.2 ± 24.7years. The questionnaire showed acceptable reliability (α=0.792), establishing 11 dimensions with 38 questions. Females showed a significantly higher average total score compared to males (p<0.001). In conclusion, implementation and validation of the questionnaire allows us to contribute a low-cost tool to know the intimate aspects of the behavior ofpeople attending public health centers.
Genotipificación del gen HLA DQB1 en diabetes autoinmune del adulto (lada) HLA DQB1 genotyping in latent autoimmune diabetes of adults (LADA)
Mariela Caputo,Gloria E. Cerrone,Ariel P. López,Claudio Gónzalez
Medicina (Buenos Aires) , 2005,
Abstract: La diabetes autoinmune es una enfermedad multifactorial causada por factores genéticos predisponentes y ambientales desencadenantes. Se manifiesta en la edad infantojuvenil (diabetes tipo 1, DMID) y en la edad adulta (diabetes autoinmune latente del adulto, LADA). La predisposición genética es de tipo poligénico, se ha establecido asociación con alelos polimórficos del gen DQB del sistema HLA, VNTR del gen de insulina y polimorfismos en el gen CTLA4. En el presente trabajo se analizaron las frecuencias de los alelos polimórficos del gen HLA DQB1 en 63 pacientes LADA, 70 pacientes DMID y 79 individuos normales. La tipificación de los alelos del gen DQB1 se llevó a cabo mediante el Kit SSP TM DQ Olerup. Se observó una mayor frecuencia del genotipo *0201-*0302 y *0201-*0201 en ambas poblaciones diabéticas con respecto a normales (p<0.05). La presencia del genotipo *0201-*0302 fue mayor en DMID que en LADA (p<0.05). Por otra parte, el análisis del alelo protector *0602 muestra una alta prevalencia en individuos normales con respecto a la población diabética. El alelo de susceptibilidad más frecuente en pacientes LADA y DMID de nuestro país fue el *0201. En conclusión, LADA presenta susceptibilidad genética dada por alelos del gen HLA DQB1 pero en forma menos determinante que en diabetes tipo 1. A su vez, el hallazgo del aumento en la frecuencia del alelo *0201, tanto en frecuencias alélicas como genotípicas permite caracterizar nuestra población de pacientes tanto LADA como DMID a diferencia de otras poblaciones en las que el alelo más frecuente es el *0302. Autoimmune diabetes is a complex, multifactorial disease caused by the interaction of genetic and environmental factors. This autoimmune diabetes is commonly manifested in childhood and adolescence with a fast onset (type 1 diabetes, IDDM) and it can occur in adult patients with a slow onset with delayed insulin requirement, (latent autoimmune diabetes in adults, LADA ). Autoimmune diabetes has strong class II HLA association mainly with DQB gene which constitutes the first susceptibility locus. However, association with the 5’INS- VNTR and CTLA-4 genes has been established. In this study, we analysed the polimorphic allele frequencies of DQB HLA gene in 63 LADA patients, 70 IDDM and 79 control subjects. The HLA DQB1 alleles typing was detected through Olerup SSP TM DQ kit using sequence specific primers. We observed a positive association of *0201-*0302 and *0201-*0201 genotypes in both types of diabetic patients compared to the control group (p<0.05). Moreover, *0201-*0302 genotype was higher in IDDM
Alteraciones histológicas en el intestino delgado en Tupinambis rufescens (Sauria: Teiidae) causadas por Diaphanocephalus galestus (Nematoda: Diaphanocephalidae)
Spinelli, C. Mónica,Fiorito de López, Luisa E.,Stiebel, Claudio
Cuadernos de Herpetología , 1992,
Abstract: Histopathological changes in the gut of the lizard T. rufescens due to the parasitic worm D. galeatus are described here. Superficial damage of the mucosae due to mechanical action of bucal capsule, without involving deeper layers; their implication in the metabolism and immunity of the host.
Reemplazo valvular aórtico utilizando la cirugía de Ross: 13 a?os de experiencia
Roura,Pablo; Salvatori,Carolina; López,Claudio E.; Guevara,Eduardo; Rodríguez Correa,Carlos; Favaloro,Roberto R.;
Revista argentina de cardiolog?-a , 2010,
Abstract: background the ross procedure has been used for decades for the treatment of aortic valve disease. despite the promising outcomes of this technique, its limited durability is one of the major drawbacks against its massive indication. objective to analyze the outcomes of the ross procedure in our oenter. material and methods we conducted a retrospective study in a cohort of patients. from july 1995 to may 2008, 198 patients underwent ross procedure with aortic root replacement technique. kaplan-meier method was used to analyze the events associated with the valve, and the variables were analyzed using the log-rank test and cox model. results mean age was 39± 13 years and 77% were raen. the procedure was indicated due to aortic stenosis (58%) and aortic regurgitation (42%). in-hospital mortality was 2.5% (5 patients). complete follow-up at 10 years was achieved in 93% of the first 165 patients. survival at 10 years was 94.8% (95% ci, 89-98) after 10 years, 95% (95% ci, 84-98) of patients did not present endocarditis and 91% (95% ci, 86-96) had no valve-related events. five patients required reoperation, 4 due to autograft dysfunction and disease of other valves. conclusions ross procedure has a low event rate after 13 years and should be considered for the treatment of aortic valve disease in selected patients.
Efecto Mozart en el Aprendizaje Práctico de la Anatomía The Mozart Effect in the Practical Learning of the Gross Anatomy
Iván Claudio Suazo Galdames,Mario Cantín López,Guillermo Enrique Salgado Alarcón,Carolina Haydée Gajardo Contreras
International Journal of Morphology , 2008,
Abstract: El término efecto Mozart comienza a utilizarse a partir de los trabajos de Rauscher et al. (1993), quienes observaron mejores resultados en tareas que requerían orientación temporo-espacial en estudiantes universitarios. El objetivo de este estudio es analizar el efecto que tiene en el aprendizaje práctico de la anatomía la aplicación de estímulos musicales relacionados con el denominado efecto Mozart. Participaron 254 estudiantes de las carreras de Odontología, Fonoaudiología y Tecnología Médica. Los grupos de estudio fueron sometidos durante toda una Unidad temática a estimulación auditiva utilizando el primer movimiento de la Sonata para dos Pianos en D Mayor (K. 448) de Mozart, los grupos controles desarrollaron su actividad práctica sin estimulación auditiva, al finalizar la unidad se realizó una evaluación práctica de reconocimiento de estructuras en el cadáver. Las medias de los resultados obtenidos fueron superiores en los sujetos sometidos a estimulación auditiva, estos resultados fueron estadísticamente significativos en las carreras de Odontología y Fonoaudiología, pero no en Tecnología Médica. The term Mozart effect begins to be used starting from the works of Rauscher et al. (1993) who observed better results in tasks that required temporo-space orientation in university students. The objective of this study is to analyze the effect that has in the practical learning of the anatomy the application of musical stimuli related with the denominated Mozart effect. This study in volved 254 participants of the careers of Dentistry, Fonoaudiology and Medical Technology. The study groups were subjected during an entire thematic Unit to auditory stimulation using the first movement of the Mozart's Sonata for Two Pianos K.448, the groups controls developed their practical activity without auditory stimulation, when concluding the unit they was carried out a practical evaluation of recognition of structures in the cadáver. The mean of the obtained results were superior in the subjected fellows to auditory stimulation, these results were statistically significant in the careers of Dentistry and Fonoaudiology, but not in Medical Technology.
Role of Superoxide Anions in the Redox Changes Affecting the Physiologically Occurring Cu(I)-Glutathione Complex
Hernán Speisky,Camilo López-Alarcón,Claudio Olea-Azar,Cristian Sandoval-Acu?a,Margarita E. Aliaga
Bioinorganic Chemistry and Applications , 2011, DOI: 10.1155/2011/674149
Abstract: The physiologically occurring copper-glutathione complex, [Cu(I)-[GSH]2], has the ability to react continually with oxygen, generating superoxide anions ( ). We addressed here the effects that superoxide removal has on the redox state of Cu(I) and GSH present in such complex and assessed the formation of Cu(II)-GSSG as a final oxidation product. In addition, we investigated the potential of a source of external to the Cu(I)-[GSH]2 complex to prevent its oxidation. Removal of from a Cu(I)-[GSH]2-containing solution, whether spontaneous or Tempol-induced, led to time-dependent losses in GSH that were greater than those affecting the metal. The losses in GSH were not accompanied by increments in GSSG but were largely accounted for by the cumulative formation of Cu(II)-GSSG molecules. Notably, the redox changes in Cu(I) and GSH were totally prevented when Cu(I)-[GSH]2 was coincubated with hypoxanthine/xanthine oxidase. Data suggest that the generation of by Cu(I)-[GSH]2 implies the obliged formation of an intermediate whose subsequent oxidation into Cu(II)-GSSG or back reduction into Cu(I)-[GSH]2 is favoured by either the removal or the addition of , respectively. 1. Introduction The Cu(I)-glutathione complex is believed to be formed within cells during the interaction between Cu2+ ions and reduced glutathione (GSH). In fact, following the exposure of either human hepatoma cells (HACs) [1, 2] or intestinal epithelial cells (Caco-2) [3] to copper, most of the metal is recovered bound to GSH molecules, forming, most likely, a Cu(I)-[GSH]2 complex. The exact biological role of the latter complex has not been fully established. Some studies suggest, however, that it may play a role as carrier of Cu(I) to copper-dependent enzymes, such as SOD [4], and to copper-storing and copper-transporting proteins, such as metallothionein [5, 6] and ceruloplasmin [7], respectively. Studies conducted in noncellular systems indicate that mixing Cu2+ ions and GSH in a molar ratio equal to or greater than 1?:?3 leads to the swift formation of Cu(I)-[GSH]2 [8–10], as in (Rx. 1) The formation of the Cu(I)-glutathione complex has been supported by 1H-NMR and EPR studies [4, 11] and would involve an initial stoichiometric reduction of Cu2+ by GSH and a subsequent chelation of the cuprous ion by two additional GSH molecules [10]. Binding of GSH has been suggested to stabilize Cu(I) in a form that, for long time, was presumed to be redox-inactive due to the relative stability that the complex exhibits in oxygen-containing solutions [4, 12–14]. Contending such concept, we recently
Genotipificación del gen HLA DQB1 en diabetes autoinmune del adulto (lada)
Caputo,Mariela; Cerrone,Gloria E.; López,Ariel P.; Gónzalez,Claudio; Mazza,Carmen; Cedola,Norberto; Puchulu,Félix M.; Targovnik,Héctor M.; Frechtel,Gustavo D.;
Medicina (Buenos Aires) , 2005,
Abstract: autoimmune diabetes is a complex, multifactorial disease caused by the interaction of genetic and environmental factors. this autoimmune diabetes is commonly manifested in childhood and adolescence with a fast onset (type 1 diabetes, iddm) and it can occur in adult patients with a slow onset with delayed insulin requirement, (latent autoimmune diabetes in adults, lada ). autoimmune diabetes has strong class ii hla association mainly with dqb gene which constitutes the first susceptibility locus. however, association with the 5?ins- vntr and ctla-4 genes has been established. in this study, we analysed the polimorphic allele frequencies of dqb hla gene in 63 lada patients, 70 iddm and 79 control subjects. the hla dqb1 alleles typing was detected through olerup ssptm dq kit using sequence specific primers. we observed a positive association of *0201-*0302 and *0201-*0201 genotypes in both types of diabetic patients compared to the control group (p<0.05). moreover, *0201-*0302 genotype was higher in iddm than in lada (p<0.05). on the other hand, the *0602 protective allele analysis showed a high prevalence in the normal group compared to the diabetic population. in argentina, the most frequent allele of susceptibility in lada and iddm patients was the *0201. summing up, the finding of an increase in the *0201 allele, both in allelic and genotypic frequencies, allows the characterisation of our population of patients, lada and iddm, unlike other populations, in which the most frequent allele is *0302.
Changes in Men’s Salivary Testosterone and Cortisol Levels, and in Sexual Desire after Smelling Female Axillary and Vulvar Scents
Ana Lilia Cerda-Molina,Leonor Hernández-López,Claudio E. de la O,Ricardo Mondragón-Ceballos
Frontiers in Endocrinology , 2013, DOI: 10.3389/fendo.2013.00159
Abstract: Several studies have shown that a woman’s vaginal or axillary odors convey information on her attractivity. Yet, whether such scents induce psychoneuroendocrinological changes in perceivers is still controversial. We studied if smelling axillary and vulvar odors collected in the periovulatory and late luteal phases of young women modify salivary testosterone and cortisol levels, as well as sexual desire in men. Forty-five women and 115 men, all of them college students and unacquainted with each other, participated in the study. Female odors were collected on pads affixed to the axilla and on panty protectors both worn the entire night before experiments. Men provided five saliva samples, a basal one before the smelling procedure, and four more 15, 30, 60, and 75 min after exposure to odors. Immediately after smelling the odor source, men answered a questionnaire rating hedonic qualities of scents, and after providing the last saliva sample they answered questionnaire on sexual desire. We found that periovulatory axillary and vulvar odors increased testosterone and cortisol levels, with vulvar scents producing a more prolonged effect. Luteal axilla odors decreased testosterone and cortisol levels, while luteal vulva odors increased cortisol. Periovulatory axilla and vulva scents accounted for a general increase of interest in sex. These odors were also rated as more pleasant and familiar, while luteal vulvar odors were perceived as intense and unpleasant.
Consulta Cubo: Chicureo, Chile
Claudio Labarca,Juan Ignacio López
ARQ , 2007,
Abstract:
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