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Search Results: 1 - 10 of 210303 matches for " Claudio P. Albuquerque "
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Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements
Claudio P. Albuquerque,Guoliang Wang,Nancy S. Lee,Richard D. Kolodner,Christopher D. Putnam,Huilin Zhou
PLOS Genetics , 2013, DOI: 10.1371/journal.pgen.1003670
Abstract: Suppression of duplication-mediated gross chromosomal rearrangements (GCRs) is essential to maintain genome integrity in eukaryotes. Here we report that SUMO ligase Mms21 has a strong role in suppressing GCRs in Saccharomyces cerevisiae, while Siz1 and Siz2 have weaker and partially redundant roles. Understanding the functions of these enzymes has been hampered by a paucity of knowledge of their substrate specificity in vivo. Using a new quantitative SUMO-proteomics technology, we found that Siz1 and Siz2 redundantly control the abundances of most sumoylated substrates, while Mms21 more specifically regulates sumoylation of RNA polymerase-I and the SMC-family proteins. Interestingly, Esc2, a SUMO-like domain-containing protein, specifically promotes the accumulation of sumoylated Mms21-specific substrates and functions with Mms21 to suppress GCRs. On the other hand, the Slx5-Slx8 complex, a SUMO-targeted ubiquitin ligase, suppresses the accumulation of sumoylated Mms21-specific substrates. Thus, distinct SUMO ligases work in concert with Esc2 and Slx5-Slx8 to control substrate specificity and sumoylation homeostasis to prevent GCRs.
Three new varieties in Ocimum L. (Lamiaceae)
Albuquerque, Ulysses P. de;
Brazilian Archives of Biology and Technology , 1999, DOI: 10.1590/S1516-89131999000100001
Abstract: three new infraspecifc taxa in ocimum are described from northeastern brazil, which were based in vegetative morphology, habit, stem indumentum or purple pigmentation; these were o. minimum var. religiosum albuquerque var. nov., o. campechianum var. pubescens albuquerque var. nov. and o. campechianum var. congestifolium albuquerque var. nov.
Revisiting the Evaluation of a Multidimensional Gaussian Integral  [PDF]
R. P. Mondaini, S. C. de Albuquerque Neto
Journal of Applied Mathematics and Physics (JAMP) , 2017, DOI: 10.4236/jamp.2017.52039
Abstract: The evaluation of Gaussian functional integrals is essential on the application to statistical physics and the general calculation of path integrals of stochastic processes. In this work, we present an elementary extension of an usual result of the literature as well as an alternative new derivation.
Tratamento de ra??es de aves com ácidos organicos: estudo da atividade bactericida e avalia??o de técnicas de recupera??o de Salmonella spp
ALBUQUERQUE, Ricardo de;ITO, Nair Massako Katayama;MIYAJI, Claudio Issamu;
Brazilian Journal of Veterinary Research and Animal Science , 1998, DOI: 10.1590/S1413-95961998000600010
Abstract: this research was designed to evaluate salmonella recovery from experimentally contaminated feeds and to compare the bactericidal and residual efficacy of acids in feeds for chickens. the bacterial recovery was successful for all of the utilized media, and on a first trial, bio addr and myco curbr were not effective in the decrease of salmonella in experimentally contaminated feeds. on a second trial, using water solution to apply the acids, bio addr and salmexr were effective. bactericidal activity on dry mix was not observed with any of the products or levels tested in feeds. in bactericidal and residual evaluations of organic acids, salmexr was effective and sal curbr was not.
Estudo da ocorrência de salmonelas em ingredientes, ra??es e suabes de pó colhidos em uma fábrica industrial de ra??o
ALBUQUERQUE, Ricardo;ITO, Nair Massako Katayama;MIYAJI, Claudio Issamu;
Brazilian Journal of Veterinary Research and Animal Science , 1999, DOI: 10.1590/S1413-95961999000600008
Abstract: this research was carried out to detect salmonela in feedstuffs (136 samples), feeds (43) and dust swabs (110) from a feed mill. salmonela was not detected in dust swabs samples. for feedstuffs, 19.85% were positive, with highest values observed from animal by-products (50%), dairy by-products (7.5%), 12.5% for other feedstuffs and 4.65% for complete feeds.
Estudo comparativo de diferentes meios de cultura para o isolamento de salmonelas em matérias-primas e ra??es
ALBUQUERQUE, Ricardo de;ITO, Nair Massako Kotayama;MIYAJI, Claudio Issamu;
Brazilian Journal of Veterinary Research and Animal Science , 2000, DOI: 10.1590/S1413-95962000000100012
Abstract: this work was designed to evaluate the efficacy of culture media for salmonella recovery in feedstuffs and feeds. all experimental samples were processed for recovery of stressed bacteria in buffered peptone water and selective media: selenite cystine (sc), rappaport vassiliadis (rv) and tetrathionate hajna (th), and solid media: brilliant green agar (bga) and xylose lisine desoxycholate (xld). higher number of positive samples was observed from th and rv as compared to sc. the th incubated at 42oc produces the bigger number of positive results, whereas the solid media bga and xld were both effective.
Maus-tratos em crian as e adolescentes com deficiência e/ou perturba es do desenvolvimento Abuse in children and adolescents with disabilities and/or developmental disorders
Vera Cruz,Cristina P. Albuquerque
Revista Brasileira de Educa??o Especial , 2013,
Abstract: A presente investiga o tem como principal objetivo analisar as características da associa o entre deficiência e/ou perturba es do desenvolvimento e maus-tratos na popula o infanto-juvenil portuguesa, e destacar as respectivas implica es no domínio da educa o especial. A amostra é constituída por 198 crian as e adolescentes com deficiência e/ou perturba es do desenvolvimento, que foram vítimas de maus-tratos. A informa o foi recolhida através de um questionário, elaborado para este fim, e respondido por psicólogos e assistentes sociais. Em termos dos resultados obtidos, verificou-se que o maltrato misto (associa o entre duas ou mais formas de maltrato) foi o mais comum, seguindo-se a negligência. Os agentes de maltrato mais frequentes foram os progenitores. A detec o dos maus-tratos foi efetuada, em regra, na etapa pré-escolar, sendo as suas principais fontes as institui es/servi os que já acompanhavam a família. Foi também detectada uma elevada percentagem de problemas de saúde física e mental, de dependências e de dificuldades de inser o social nos pais destas crian as/adolescentes. A quase generalidade das crian as e famílias beneficiou de alguma interven o após a sinaliza o dos maus-tratos. No que respeita a conclus es, e uma vez que os maus-tratos tendem a ocorrer cedo e em famílias com múltiplos fatores de risco, apontam-se estratégias de interven o familiar e sublinha-se a importancia que os programas de interven o precoce podem revestir. Também se indica o papel que os professores podem desempenhar na detec o dos maus-tratos e real a-se a relevancia e a composi o dos programas direcionados para o ensino de estratégias de prote o e autodefesa. This study analyses characteristics of the association between disability and/or developmental disorders and abuse among Portuguese children and youth. It also underscores the consequences of this association for special education. The sample consists of 198 children and adolescents with disabilities and/or developmental disorders that were abused. The data was collected using a checklist designed specifically for this study, completed by psychologists and social workers. The results showed that the most frequent type of abuse was a combination of two or more types of maltreatment, followed by neglect. The most frequent perpetrators were the parents, who were also the children's main caretakers. Abuse was identified early, usually at age 4, and mainly by institutions or services that were already following the families. A high percentage of physical and mental health problems, substance ab
La computadora en la capacitación
Périssé, Marcelo Claudio
Técnica Administrativa , 2003,
Abstract: El presente trabajo expone un modelo para crear un software educativo que permita dimensionar los usos de la web, y propone una motivación a los participantes del proceso ense anza/aprendizaje, para la utilización de la Biblioteca Digital como la entidad que les posibilitará tener el acceso a los espacios de información de forma ordena, distribuida y compartida.
El comercio electrónico en una sociedad informatizada
Périssé, Marcelo Claudio
Técnica Administrativa , 2002,
Abstract: consecuencia de la evolución organizacional, lograda a través del conocimiento que poseen las personas que la componen, y del estado de informatización en que se encuentra la sociedad en la que la empresa se desenvuelve
La computadora en la capacitación del administrador
Périssé, Marcelo Claudio
Técnica Administrativa , 2002,
Abstract: Propone una motivación, a los participantes del proceso Ense anza - Aprendizaje, para la utilización de diagramas de modelización aplicados a la capacitación en el uso de la Tecnología de la Información
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