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Search Results: 1 - 10 of 23067 matches for " Chunli Yuan "
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The Crisis Management of Enterprise's Collective Brain Drain
Chunli Yuan,Chunying Zhang
International Business Research , 2009, DOI: 10.5539/ibr.v1n4p104
Abstract: This paper take enterprise's collective brain drain as the research object, by using of questionnaire method, historical data, experts consultation method, and other methods of construct the collective brain drain of forewarning indicators, and then use the alternative ranking method to determine and evaluate comprehensively system of indicators to the weight. By constructing the forewarning system to real-time monitor, identify, diagnose and evaluate the trend of enterprise's collective brain drain and on this basis to pre-control, the prior development of corrective measures, the crisis will be resolved in the embryonic stage. Therefore, constructing the forewarning system of enterprise's collective brain drain for the long-term stable development of enterprises has important practical significance.
Self-assembled structure of alkyloxy substituted benzoic acid methyl ester on HOPG: An STM study
Qunhui Yuan,Jun Lu,Lijun Wan,Chunli Bai
Chinese Science Bulletin , 2004, DOI: 10.1360/04wb0090
Abstract: Self-assembled structures of 3,4,5-tris-dodecyloxy benzoic acid methyl ester (E12), 3,4,5-tris-tetradecyloxy-benzoic acid methyl ester (E14) and their mixture (E12/E14) have been studied on HOPG by scanning tunneling microscopy (STM). Dimer-like patterns induced by dipole-dipole interaction are observed in E12 and E14 monolayers. The molecules form close-packed rows and interdigitate with the alkyl chains in adjacent molecules. The structural differences are proposed to be from the different length of substituted alkyl chains. Owing to similar adsorption energy, phase separation is observed in the E12 and E14 mixed adlayer with different domains.
Angiotensin-Converting Enzyme 2 Deficiency Aggravates Glucose Intolerance via Impairment of Islet Microvascular Density in Mice with High-Fat Diet
Li Yuan,Ying Wang,Chunli Lu,Xiaoya Li
Journal of Diabetes Research , 2013, DOI: 10.1155/2013/405284
Abstract:
Angiotensin-Converting Enzyme 2 Deficiency Aggravates Glucose Intolerance via Impairment of Islet Microvascular Density in Mice with High-Fat Diet
Li Yuan,Ying Wang,Chunli Lu,Xiaoya Li
Journal of Diabetes Research , 2013, DOI: 10.1155/2013/405284
Abstract: The aim of this study was to evaluate the effects of angiotensin-converting enzyme 2 (ACE2) on glucose homeostasis and islet function in mice. Male wildtype (WT) and ACE2 knockout (ACE2 KO) mice were divided into chow diet group and long-term high-fat diet (HFD) group. After 16 weeks of feeding, the islet function of the animals was evaluated by intraperitoneal glucose tolerance test (IPGTT) and intraperitoneal insulin releasing test (IPIRT). The pancreas was immunohistochemically stained to analyze the relative content of insulin (IRC), vascular endothelial growth factor (VEGF), and microvessel density (MVD) in islets. There was no difference of body weight, area under curve of glucose (AUCG), area under curve of insulin from 0 to 5?min (AUGI0–5), MVD, and RVC (relative content of VEGF) between WT and ACE2 KO mice with regular chow diet. Under the condition of long-term HFD, the AUCG of ACE2 KO mice was increased obviously in comparison with the WT mice, with decreased IRC, MVD, AUGI0–5, AUCI0–30, and RVC (all ). In conclusion, these results show that ACE2 deficiency deteriorates islet function of mice with long-term HFD via impairment of islet microvasculature. 1. Introduction The classical renin-angiotensin system (RAS), ACE-Ang II-AT1 receptor axis, is a coordinated hormonal cascade facilitating the dynamic control of perfusion in both health and disease [1]. In 2000, a new member of the RAS, ACE2, was discovered by two independent groups [2, 3]. ACE2 is capable of metabolizing Ang II to generate Ang (1-7) [4]. Ang (1-7) interacting with its receptor Mas elicits numerous actions that counterbalance those of Ang II [5]. Accumulating evidence have indicated that ACE2-Ang (1-7)-Mas axis acts as a negative regulator of the ACE-Ang II-AT1 receptor axis [6]. During the past decades, the existence of a local RAS has been confirmed in both the endocrine and exocrine pancreas [7–9]. In 1991, an intrinsic RAS in the pancreas was firstly described by Chappell et al. [10]. Lau et al. [11] identified the expression of several RAS components in mouse pancreatic islet, such as angiotensinogen, ACE, AT1, and AT2 receptors. The evidence for the existence of these above components were also observed in human pancreas [12]. In addition, ACE2 mRNA and protein have been identified in the pancreatic islets [13]. Canine pancreatic Ang (1-7) [10] and rat pancreatic Mas receptor have also been confirmed [14]. Previous studies [15, 16] have provided additional evidence for the close association of RAS with pancreatic endocrine physiology and its pathophysiology. Islet
Temperature Calculation of Pellet Rotary Kiln Based on Texture  [PDF]
Chunli Lin, Yufan Wu
Intelligent Control and Automation (ICA) , 2017, DOI: 10.4236/ica.2017.82005
Abstract: In order to improve the quality of clinker produced by pellet rotary kiln, flame temperature that it is a very important factor of affecting on the quality of clinker is studied. The flame images collected from pellet rotary kiln are decomposed into three gray images by the method of RGB, so we can get more information of flame. Taking advantage of gray level co-occurrence matrix, the monitoring model for flame temperature based on image texture is established with RGB channels. In order to test the universality of the algorithm, candle flame temperature is detected by this method. The maximum error of the model is less than 3%.
Dual effects of α-synuclein on neurotoxicity induced by low dosage of rotenone are dependent on exposure time in dopaminergic neuroblastoma cells
LingLing Lu,Li Gu,Yuan Liang,XiaoHong Sun,ChunLi Duan,Hui Yang
Science China Life Sciences , 2010, DOI: 10.1007/s11427-010-0104-6
Abstract: This study was designed to investigate the effects of α-synuclein on toxicity induced by long-term exposure to relatively low concentrations of rotenone. Compared with the control groups, the inhibition of cell viability which overexpressed α-synuclein (SH-SY5Y-Syn) improved after 1 and 2 weeks of rotenone treatment. The complex I activity was greater and the mitochondrial membrane swelling intensity was reduced after 1 and 2 weeks of treatment, which indicated that α-synuclein, at least in part, resists the rotenone-induced oxidative stress. The results indicate that α-synuclein has a dual effect on toxicity of rotenone according to exposure time in human SH-SY5Y cells.
Translation of English and Chinese Addressing Terms from the Cultural Aspect
Chunli Yang
Journal of Language Teaching and Research , 2010, DOI: 10.4304/jltr.1.5.738-742
Abstract: Terms of address are frequently used in social communication to show the identity, rank and relationship between the speaker and the hearer. It is important to have a profound understanding of addressing terms, especially in cross-cultural communication. However, due to the difference in history, religion and culture, terms of address vary in different countries and regions. In this paper, the author discusses the translation of English and Chinese addressing terms from the aspect of cultural background. First, the author defines terms of address and gives the reason why people use terms of address in social communication. Then, the differences between English and Chinese terms of address are analyzed from the point of kinship terms and social terms of address. Last, four translation methods are given according to different situations, namely, literal translation, translating flexibly, specification or generalization and domestication and foreignization.
Cultural Differences on Chinese and English Idioms of Diet and the Translation
Chunli Yang
English Language Teaching , 2010, DOI: 10.5539/elt.v3n1p148
Abstract: Idioms is a special culture which is shaped in the daily lives of the local people, particularly the idioms of diet has a close relation with various elements, such as the eating custom , history, fairy tales, geographic situations. Also, different ways of translation on different diet idioms in English and Chinese will be analyzed in this article. As a result, it will be very important to know the great culture contents in the idioms of diet in order to do a better job in the research of cross-culture communication and the translation.
Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated Kinase-1
Ling Zhou, Chunli Yan, Roben G Gieling, Yujiro Kida, Warren Garner, Wei Li, Yuan-Ping Han
BMC Immunology , 2009, DOI: 10.1186/1471-2172-10-15
Abstract: In response to TNF-alpha or IL-1alpha, PAK1 was promptly activated, as characterized by a sequential phosphorylation, initiated at threonine-212 followed by at threonine-423 in the activation loop of the kinase, in human skin keratinocytes, dermal fibroblasts, and rat hepatic stellate cells. Ectopic expression of PAK1 variants, but not p38 MAP kinase, impaired the TNF-alpha-induced MMP-9 expression, while other MMPs such as MMP-2, -3 and -14 were not affected. Activation of Jun N-terminal kinase (JNK) and NF-kappaB has been demonstrated to be essential for MMP-9 expression. Expression of inactive PAK1 variants impaired JNK but not NF-kappaB activation, which consequently suppressed the 5'-promoter activities of the MMP-9 gene. After the cytokine-induced phosphorylation, both ectopically expressed and endogenous PAK1 proteins were promptly accumulated even in the condition of suppressing protein synthesis, suggesting the PAK1 protein is stabilized upon TNF-alpha stimulation. Stabilization of PAK1 protein by TNF-alpha treatment is independent of the kinase catalytic activity and p21 GTPase binding capacities. In contrast to epithelial cells, mesenchymal cells require 3-dimensional type-I collagen in response to TNF-alpha to massively express MMP-9. The collagen effect is mediated, in part, by boost JNK activation in a way to cooperate the cytokine signaling.We identified a novel mechanism for MMP-9 expression in response to injury signals, which is mediated by PAK1 activation and stabilization leading JNK activation.Degradation of extracellular matrix (ECM), as mediated by matrix metalloproteinases (MMPs) and antagonized by tissue inhibitors of matrix metalloproteinases (TIMPs), is critical for embryonic development and adult tissue homeostasis [1,2]. Conversely, uncontrolled ECM degradation occurs in many degenerative diseases [3,4]. For instance, excessive presence of MMPs has been well documented in cancer dissemination, arthritis development, and chronic wound pro
A New Specific Property of Schweizer-Sklard Operators
Chunli WANG,Shiqiang ZHANG
Studies in Mathematical Sciences , 2011, DOI: 10.3968/1975
Abstract: A new specific property of Schweizer-Sklard operators is discovered that Schweizer-Sklard operations are continued fuzzy operators. The relation between Schweizer-Sklard operators and other Fuzzy operators is analysis. The conclusion that Schweizer-Sklard operations could partly replace other fuzzy operations most in use is given. At the same time the relation between Schweizer-Sklard operations and Zadeh operations as well as probability operators is given.
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