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Search Results: 1 - 10 of 18493 matches for " Chunchao Han "
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Using Integrating Method to Teach Biochemical Pharmacy Technology  [PDF]
Chunchao Han
Creative Education (CE) , 2010, DOI: 10.4236/ce.2010.13021
Abstract: An integrating method to teach Biochemical Pharmacy Technology was developed to help students understand the technology to produce biochemical pharmacy well in this paper. By the integrating method, students can compare the main content of the biochemical pharmacy and the technology to produce them. Students were encouraged to demonstrate the connection and difference of the various biochemical pharmacies. The results showed that the performance of students with integrating method is significantly better than that of students without integrating method (p < 0.05). In conclusion, integrating method can enhance students’ performance on Biochemical Pharmacy Technology.
A Hypothesis: Supplementation with Mushroom-Derived Active Compound Modulates Immunity and Increases Survival in Response to Influenza Virus (H1N1) Infection
Han Chunchao,Jian-you Guo
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1093/ecam/neq037
Abstract: We hypothesize that the mushroom-derived active compound may be a potential strategy for increasing survival in response to influenza virus (H1N1) infection through the stimulation of host innate immune response. The validity of the hypothesis can be tested by immune response to influenza infection as seen through survival percentage, virus clearance, weight loss, natural killer cell cytotoxicity, Tumor Necrosis Factor-α (TNF-α) and Interferon-gamma (IFN-γ) levels, lytic efficiency in the spleens of mice and inducible nitric oxide synthase mRNA expressions in RAW 264.7 murine macrophage cells. The hypothesis may improve people's quality of life, reduce the medical cost of our healthcare system and eliminate people's fears of influenza outbreak.
Isolation and biological activity of triglycerides of the fermented mushroom of Coprinus Comatus
Jun Ren, Jin-Li Shi, chunchao han, Zhen-Quan Liu, jianyou guo
BMC Complementary and Alternative Medicine , 2012, DOI: 10.1186/1472-6882-12-52
Abstract: The effects of TFC on cytokines levels, total antioxidant activity, antinociceptive effects in vivo, LD50 and tactile hyperalgesia were analyzed respectively.TFC treatment decreased the levels of cytokines and total antioxidant status (TAOS) and inhibited the acetic acid-induced abdominal constrictions in mice. In addition, TFC reduced CFA-induced tactile hyperalgesia in a dose-dependent manner and the LD50 of TFC was determined to be 400?mg/kg. However, TFC did not significantly inhibit the reaction time to thermal stimuli in the hot-plate test.TFC showed anti-inflammatory, antioxidant, peripheral antinociceptive and antihyperalgesic activity in various models of inflammatory pain. The data suggest that TFC may be a viable treatment option for inflammatory pain.
Design of Library Management System  [PDF]
Chunchao Liu, Sheng Ma
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104974
Abstract:
The library management system runs on the DOS system, based on the C lan-guage as the main programming language and Visual C as the development environment. According to the characteristics of the system, we construct the development model and then build structural analysis, system function modules and system flow chart through the demand analysis of the system. Through the analysis of each function module, the definition and attributes of the data and the realization of each function are determined. In the paper, the design of the library management system includes the user module, the administrator module and the module of tourists and also achieves the usual function including borrowing books, returning books and books management.
Modeling of IEEE1588 on OPNET and Analysis of Asymmetric Synchronizing Error in Smart Substation  [PDF]
Jiongcong Chen, Haizhu Wang, Chunchao Hu, Kai Ma, Zexiang Cai
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.54B103
Abstract:

The IEEE1588 network time synchronization, matched with smart substation information network transmission, is becoming the next generation advanced data synchronization of the smart substation. It is known that the inherent asymmetry error of the network synchronization approach in the smart substation is highlighted, which is concerned particularly. This paper models the synchronization process of the IEEE1588 based on the communication simulation software of OPNET Modeler. Firstly, it builds the models of master-slave clock, IEEE1588 protocol and network synchroniza- tion model, and analyzes the composition and influencing factors of the asymmetry error. Secondly, it quantitatively analyzes the influence of the synchronous asymmetric error of the IEEE1588 affected by the network status differences and the clock synchronization signal transmission path differences. Then its correction method is analyzed, in order to improve the IEEE1588 synchronization reliability and gives the solutions to its application in smart substation.

Oil Spill Model Operational Application in Damage Assessment and Case Study of Validation  [PDF]
Bing Qiao, Feng Xiao, Ru Lan, Tao Li, Chunchao Li
Journal of Environmental Protection (JEP) , 2018, DOI: 10.4236/jep.2018.95033
Abstract: Oil spill modeling is an important technical measure to evaluate the impact of oil spills scientifically. Because of the great uncertainty in its early development, simulation results have not been used as the basis of judgments for environmental compensation cases. Despite this, scientific research institutes in many countries, including China, are still devoted to the research and development of oil spill models and their applications in environmental damage assessment, which makes it possible to apply them in the judicial arbitration of damages claims. The relevant regulations on the Chinese compensation fund for oil pollution damage from ships and the judicial authentication of environmental damage have also accredited such kind of modeling applications. In order to enhance the applicability of oil spill model further, it is necessary to expand its damage assessment function, and to test, calibrate and verify the accuracy of the evaluation. To this end, the author adopts the self-developed 3-dimentionaloil spill model—CWCM to simulate the “Tasman Sea” oil spill accident. By comparing the simulation results of tidal current field, wind field, oil spill trajectory with those observed, the model coding and parameter selection are corrected, and it is realized that the simulation being basically consistent with the measured results. In addition, the results of the scale reduced simulation test of oil spill weathering are applied verifying and perfecting the weathering model of CWCM. The technical requirements and process for operational application of oil spill model in judicial arbitration are also put forward. In view of the rapid simulation function, the operational updating program for oil spill weathering model, coupled current model and dynamic update wind field diagnostic model are put forward in order to further improve the operational evaluation function and evaluation efficiency of oil spill model.
Optimization of Conditions for Charantin Extraction in PEG/Salt Aqueous Two-Phase Systems Using Response Surface Methodology
Chunchao HanJihui WangMomordica charantiaMomordica charantia withp
The Open Complementary Medicine Journal , 2009, DOI: 10.2174/1876391X00901010046]
Abstract: Momordica charantia, commonly known as karela or bitter melon, is used as a vegetable in Chinese, Indian subcontinent. However, in Chinese traditional medicine, the plant is usually used as an antidiabetic agent. One of the active components is charantin. Aqueous two-phase systems (ATPS) were used for the purifying saponin because of their low cost. ATPS can reduce amount of organic solvent and the danger of explosion necessitates special equipment leading to increased costs. The levels of blood glucose decreased after administration of charantin purified from Momordica charantia with (ATPS (p<0.05).
A proteomic analysis of allograft rejection in rats after liver transplantation
ChunChao Zhang,Feng Zhu,JianFeng Wei,ShuSen Zheng,LanJuan Li
Science China Life Sciences , 2007, DOI: 10.1007/s11427-007-0038-9
Abstract: In order to understand the allograft rejection in orthotopic liver transplantation (OLT), an allograft rejection rat model was established and studied by proteomic approach. The protein expression profiles of liver tissues were acquired by fluorescence two-dimensional difference gel electrophoresis (2D DIGE) that incorporated a pooled internal standard and reverse fluorescent labeling method. The expression levels of 27 protein spots showed significant changes in acute rejection rats. Among these spots, 19 were identified with peptide mass fingerprinting using matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) after tryptic in-gel digestion. The results of the present paper could be helpful for our better understanding of allograft rejection in organ transplantation.
A proteomic analysis of allograft rejection in rats after liver transplantation

ZHANG chunchao,ZHU feng,WEI jianfeng ZHENG shusen LI lanjuan,

中国科学C辑(英文版) , 2007,
Abstract: In order to understand the allograft rejection in orthotopic liver transplantation (OLT), an allograft rejection rat model was established and studied by proteomic approach. The protein expression profiles of liver tissues were acquired by fluorescence two-dimensional difference gel electrophoresis (2D DIGE) that incorporated a pooled internal standard and reverse fluorescent labeling method. The expression levels of 27 protein spots showed significant changes in acute rejection rats. Among these spots, 19 were identified with peptide mass fingerprinting using matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) after tryptic in-gel digestion. The results of the present paper could be helpful for our better understanding of allograft rejection in organ transplantation. These authors contributed equally to this work Supported by the Key Basic Research and Development Program of China (Grant No. 2003CB515506), and in part by the Chinese Human Liver Proteome Project (CNHLPP) (Grant No. 2004BA711A18)
Solving Large Scale Nonlinear Equations by a New ODE Numerical Integration Method  [PDF]
Tianmin Han, Yuhuan Han
Applied Mathematics (AM) , 2010, DOI: 10.4236/am.2010.13027
Abstract: In this paper a new ODE numerical integration method was successfully applied to solving nonlinear equations. The method is of same simplicity as fixed point iteration, but the efficiency has been significantly improved, so it is especially suitable for large scale systems. For Brown’s equations, an existing article reported that when the dimension of the equation N = 40, the subroutines they used could not give a solution, as compared with our method, we can easily solve this equation even when N = 100. Other two large equations have the dimension of N = 1000, all the existing available methods have great difficulties to handle them, however, our method proposed in this paper can deal with those tough equations without any difficulties. The sigularity and choosing initial values problems were also mentioned in this paper.
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