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Search Results: 1 - 10 of 240249 matches for " Christian R. Salazar "
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Asociación de polimorfismos de los genes CRF-BP, SLC6A4 y restricción alimentaria crónica: un estudio preliminar
Sanhueza,Jorge A; Herrera,Christian L; Salazar,Luis A; Silva,Jaime R;
Revista médica de Chile , 2011, DOI: 10.4067/S0034-98872011001000003
Abstract: background: restrained eaters (re) are a group of individuals who constantly restrict their eating. however, they usually alternate restriction with periods of overeating. aim: to evaluate the possible association of crf-bp and slc6a4 gene polymorphisms with chronic alimentary restriction. material and methods: the spanish version of the revised restraint scale was applied to 132 women aged 18 to 25 years. they were divided in a group classified as restrained eaters (re) and a group of unrestrained eaters. the 5-httlpr and crf-bps11 polymorphisms of the slc6a4 and crf-bp genes were evaluated by polymerase chain reaction (pcr) and pcr-restriction fragment length polymorphism (rflp), respectively. results: there was a significant association between the s/s homozygous genotype for the 5-httlpr polymorphism of slc6a4 gene and re condition (p = 0.033). however, this association was not observed for the crf-bps11 polymorphism. conclusions: the presence of s/s genotype is associated with the re condition, being the presence of a s allele, a risk factor for this condition.
Asociación de polimorfismos de los genes CRF-BP, SLC6A4 y restricción alimentaria crónica: un estudio preliminar CRF-BP and SLC6A4 gene polymorphisms among restrained eaters
Jorge A Sanhueza,Christian L Herrera,Luis A Salazar,Jaime R Silva
Revista médica de Chile , 2011,
Abstract: Background: Restrained eaters (RE) are a group of individuals who constantly restrict their eating. However, they usually alternate restriction with periods of overeating. Aim: To evaluate the possible association of CRF-BP and SLC6A4 gene polymorphisms with chronic alimentary restriction. Material and Methods: The Spanish version of the Revised Restraint Scale was applied to 132 women aged 18 to 25 years. They were divided in a group classified as restrained eaters (RE) and a group of unrestrained eaters. The 5-HTTLPR and CRF-BPs11 polymorphisms of the SLC6A4 and CRF-BP genes were evaluated by polymerase chain reaction (PCR) and PCR-restriction fragment length polymorphism (RFLP), respectively. Results: There was a significant association between the s/s homozygous genotype for the 5-HTTLPR polymorphism of SLC6A4 gene and RE condition (p = 0.033). However, this association was not observed for the CRF-BPs11 polymorphism. Conclusions: The presence of s/s genotype is associated with the RE condition, being the presence of a s allele, a risk factor for this condition.
Active Fluctuation Symmetries
Christian Maes,Alberto Salazar
Physics , 2013, DOI: 10.1088/1367-2630/16/1/015019
Abstract: In contrast with the understanding of fluctuation symmetries for entropy production, similar ideas applied to the time-symmetric fluctuation sector have been less explored. Here we give detailed derivations of time-symmetric fluctuation symmetries in boundary driven particle systems such as the open Kawasaki lattice gas and the zero range model. As a measure of time-symmetric dynamical activity we take the difference $(N_1 - N_L)/T$ in the number of particles entering or leaving the system at the left versus the right edge of the system over time $T$. We show that this quantity satisfies a fluctuation symmetry from which we derive a new Green-Kubo type relation. It will follow then that the system is more active at the edge connected to the particle reservoir with the largest chemical potential. We also apply these exact relations derived for stochastic particle models to a deterministic case, the spinning Lorentz gas, where the symmetry relation for the activity is checked numerically.
Linear response in the nonequilibrium zero range process
Christian Maes,Alberto Salazar
Physics , 2013, DOI: 10.1016/j.chaos.2013.09.004
Abstract: We explore a number of explicit response formulae around the boundary driven zero range process to changes in the exit and entrance rates. In such a nonequilibrium regime kinetic (and not only thermodynamic) aspects make a difference in the response. Apart from a number of formal approaches, we illustrate a general decomposition of the linear response into entropic and frenetic contributions, the latter being realized from changes in the dynamical activity at the boundaries. In particular, in this way one obtains nonlinear modifications to the Green-Kubo relation. We end by bringing some general remarks about the situation where that nonequilibrium response remains given by the (equilibrium) Kubo formula such as for the density profile in the boundary driven Lorentz gas.
Association between Selected Oral Pathogens and Gastric Precancerous Lesions
Christian R. Salazar, Jinghua Sun, Yihong Li, Fritz Francois, Patricia Corby, Guillermo Perez-Perez, Ananda Dasanayake, Zhiheng Pei, Yu Chen
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0051604
Abstract: We examined whether colonization of selected oral pathogens is associated with gastric precancerous lesions in a cross-sectional study. A total of 119 participants were included, of which 37 were cases of chronic atrophic gastritis, intestinal metaplasia, or dysplasia. An oral examination was performed to measure periodontal indices. Plaque and saliva samples were tested with real-time quantitative PCR for DNA levels of pathogens related to periodontal disease (Porphyromonas gingivalis, Tannerella forsythensis, Treponema denticola, Actinobacillus actinomycetemcomitans) and dental caries (Streptococcus mutans and S. sobrinus). There were no consistent associations between DNA levels of selected bacterial species and gastric precancerous lesions, although an elevated but non-significant odds ratio (OR) for gastric precancerous lesions was observed in relation to increasing colonization of A. actinomycetemcomitans (OR = 1.36 for one standard deviation increase, 95% Confidence Interval = 0.87–2.12), P. gingivalis (OR = 1.12, 0.67–1.88) and T. denticola (OR = 1.34, 0.83–2.12) measured in plaque. To assess the influence of specific long-term infection, stratified analyses by levels of periodontal indices were conducted. A. actinomycetemcomitans was significantly associated with gastric precancerous lesions (OR = 2.51, 1.13–5.56) among those with ≥ median of percent tooth sites with PD≥3 mm, compared with no association among those below the median (OR = 0.86, 0.43–1.72). A significantly stronger relationship was observed between the cumulative bacterial burden score of periodontal disease-related pathogens and gastric precancerous lesions among those with higher versus lower levels of periodontal disease indices (p-values for interactions: 0.03–0.06). Among individuals with periodontal disease, high levels of colonization of periodontal pathogens are associated with an increased risk of gastric precancerous lesions.
Reply to the Comment on``Scaling Laws for a System with Long--Range Interactions within Tsallis Statistics''
R. Salazar,R. Toral
Physics , 2000,
Abstract: The fact that mean field theory is appropriate to describe an Ising model with long-range interactions has been already shown by Cannas and Tamarit. Although not explicited in our Letter, we have used periodic boundary conditions in all our simulations, such that the maximum possible distance between two lattice sites is L/2. We make no specific comments about the validity (or lack of validity) of Boltzmann-Gibbs statistical mechanics to describe long-range systems. Our paper does nothing but to compare the scaling functions derived from Boltzman-Gibbs statistics from those derived from the use of Tsallis entropy.
Thermostatistics of extensive and non-extensive systems using generalized entropies
R. Salazar,R. Toral
Physics , 2000, DOI: 10.1016/S0378-4371(00)00361-7
Abstract: We describe in detail two numerical simulation methods valid to study systems whose thermostatistics is described by generalized entropies, such as Tsallis. The methods are useful for applications to non-trivial interacting systems with a large number of degrees of freedom, and both short-range and long-range interactions. The first method is quite general and it is based on the numerical evaluation of the density of states with a given energy. The second method is more specific for Tsallis thermostatistics and it is based on a standard Monte Carlo Metropolis algorithm along with a numerical integration procedure. We show here that both methods are robust and efficient. We present results of the application of the methods to the one-dimensional Ising model both in a short-range case and in a long-range (non-extensive) case. We show that the thermodynamic potentials for different values of the system size N and different values of the non-extensivity parameter q can be described by scaling relations which are an extension of the ones holding for the Boltzmann-Gibbs statistics (q=1). Finally, we discuss the differences in using standard or non-standard mean value definitions in the Tsallis thermostatistics formalism and present a microcanonical ensemble calculation approach of the averages.
Simulated Annealing using Hybrid Monte Carlo
R. Salazar,R. Toral
Physics , 1997, DOI: 10.1007/BF02764221
Abstract: We propose a variant of the Simulated Annealing method for optimization in the multivariate analysis of differentiable functions. The method uses global actualizations via the Hybrid Monte Carlo algorithm in their generalized version for the proposal of new configurations. We show how this choice can improve upon the performance of simulated annealing methods (mainly when the number of variables is large) by allowing a more effective searching scheme and a faster annealing schedule.
Scaling functions for Tsallis non--extensive statistics
R. Salazar,R. Toral
Physics , 1999,
Abstract: We study the one-dimensional Ising model with long-range interactions in the context of Tsallis non-extensive statistics by computing numerically the number of states with a given energy. We find that the internal energy, magnetization, entropy and free energy follow non-trivial scaling laws with the number of constituents $N$ and temperature $T$. Each of the scaling functions for the internal energy, the magnetization and the free energy, adopts three different forms corresponding to $q>1$, $q=1$ and $q<1$, being $q$ the non-extensivity parameter of Tsallis statistics.
Reconstruyendo la política de los movimientos sociales
Róbinson Salazar P.
Revista Theomai , 2007,
Abstract:
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