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Scorpion Sting: A 2-Year Study
B Chomeili
Iranian Journal of Pediatrics , 1998,
Abstract: Scorpion sting and its complications are a serious pediatric problem in district Khuzestan, especially in the warm months of the year (May through November in this area). During 2 years (March 1991-march 1993) totally 10559 cases of scorpion sting have been referred to the scorpion envonimation unit in Aboozar children's hospital, which being the only scorpion sting center in the district is active 1981. 154 cases had to be admitted because of severe complications such as extensive ecchymosis and necrosis of the sting site, severe hemolysis and dark urine, toxic appearance, convulsions, hematemesis, hypotension, pulmonary edema, cardiac heart failure and death. 90% of the admitted cases had been stung by hemiscorpius lepturus, a dangerous scorpion called "Gadim" in Khuzestan. 19 out of 20 fatalities were caused by this scorpion. Unfortunately, the available antivenoms have no effect on this kind of scorpion venom. To reduce casualties, good scorpion control and eradication, intensive protective care, and preparation of specific antivenom must be taken into consideration.
Prevalence of celiac disease in siblings of Iranian patients with celiac disease
Chomeili, Bashir;Aminzadeh, Majid;Hardani, Amir Kamal;Fathizadeh, Payam;Chomeili, Pooya;Azaran, Azarakhsh;
Arquivos de Gastroenterologia , 2011, DOI: 10.1590/S0004-28032011000200009
Abstract: context: celiac disease, one of the best-known autoimmune human leukocyte antigen-dependent disorders, has a relatively increased prevalence in first-degree relatives. objective: to determine the prevalence of celiac disease in siblings of patients with confirmed celiac disease. methods: siblings of confirmed celiac disease patients in our center were identified and enrolled in this study. their serum immunoglobulin a and tissue transglutaminase antibody-enzyme-linked immunosorbent assay (anti-tissue transglutaminase, immunoglobulin a, and immunoglobulin g) were measured and multiple endoscopic duodenal biopsy specimens were obtained with parental consensus. celiac disease was confirmed by observation of characteristic histological changes. results: a total of 49 children (male, 29; female, 20; age, 2-16 years) with confirmed celiac disease in a pediatric gastroenterology ward were studied from 1999 to 2006. we found 30 siblings (female, 16) all shared in both parents. the only measurement available was for immunoglobulin a tissue transglutaminase antibody. a duodenal biopsy was performed in all 30 siblings. clinical findings such as abdominal pain, fatigue, growth retardation and diarrhea were found in 53.3% of the completely studied siblings, and positive serology without histological changes was identified in four cases. both serology and biopsy (confirmed new cases) were positive in 2 of the 30 siblings. conclusion: high prevalence of celiac disease among siblings of patients with confirmed celiac disease necessitates serologic screening (and confirmatory biopsy if indicated) in families having celiac disease. it is advantageous to diagnose the disease as soon as possible because early diagnosis and diet intervention may prevent serious complications such as growth retardation, short stature, chronic diarrhea, and malignancy.
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