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Search Results: 1 - 10 of 37597 matches for " Cheng-Xiong Mao "
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Harmonic Propagation and Interaction Evaluation between Small-Scale Wind Farms and Nonlinear Loads
Guang-Long Xie,Bu-Han Zhang,Yan Li,Cheng-Xiong Mao
Energies , 2013, DOI: 10.3390/en6073297
Abstract: Distributed generation is a flexible and effective way to utilize renewable energy. The dispersed generators are quite close to the load, and pose some power quality problems such as harmonic current emissions. This paper focuses on the harmonic propagation and interaction between a small-scale wind farm and nonlinear loads in the distribution grid. Firstly, by setting the wind turbines as P – Q( V) nodes, the paper discusses the expanding Newton-Raphson power flow method for the wind farm. Then the generalized gamma mixture models are proposed to study the non-characteristic harmonic propagation of the wind farm, which are based on Gaussian mixture models, improved phasor clustering and generalized Gamma models. After the integration of the small-scale wind farm, harmonic emissions of nonlinear loads will become random and fluctuating due to the non-stationary wind power. Furthermore, in this paper the harmonic coupled admittance matrix model of nonlinear loads combined with a wind farm is deduced by rigorous formulas. Then the harmonic propagation and interaction between a real wind farm and nonlinear loads are analyzed by the harmonic coupled admittance matrix and generalized gamma mixture models. Finally, the proposed models and methods are verified through the corresponding simulation models in MATLAB/SIMULINK and PSCAD/EMTDC.
Off-pump coronary artery bypass grafting using a bilateral internal mammary artery Y graft
Cheng-Xiong Gu,Jun-Feng Yang,Hong-Chao Zhang,Hua Wei
老年心脏病学杂志(英文版) , 2012,
Abstract: ObjectiveTo evaluate the outcome of off-pump coronary artery bypass grafting (OPCABG) using a bilateral internal mammary artery (BIMA) Y configuration graft to achieve total arterial myocardial revascularization. Methods From October 2002 to December 2008, 208 patients (196 males and 12 females) underwent OPCABG using a BIMA Y configuration graft. The average age of the patients was 56.5 ± 11.3 years, with an age range of 33–78 years. A total of 167 (80.2%) cases had triple-vessel disease. Left main stem disease was found in 33 (15.9%) cases, and double-vessel disease was found in 8 (3.9%) cases. The semi-skeletonization technique was used to harvest the two internal mammary arteries (IMAs), and then the free right internal mammary artery was connected end-to-side to the left internal mammary artery (LIMA) in situ to complete the Y configuration graft. Off-pump and sequential anastomosis methods were used to perform coronary artery bypass surgery in all patients. Graft patency was assessed intra-operatively with the HT311 transit time flowmeter. Results A total of 728 distal anastomoses were performed in 208 patients, with the average being 3.5 ± 1.3 per person. No one died or experienced recurrent angina within 30 days after the operation. Conclusions OPCABG using the BIMA Y graft was safe and effective to achieve total arterial revascularization. This method avoids surgical operation on the ascending aorta and other incisions.
Outcomes of Middle Cardiac Vein Arterialization via Internal Mammary/Thoracic Artery Anastomosis
Yang Yu, Hai-tao Li, Ming-xin Gao, Fan Zhang, Cheng-xiong Gu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080963
Abstract: Objective Cardiac vein arterialization is seldom applied for treating right coronary artery disease. This study aimed to improve outcomes of cardiac vein arterialization in a porcine model using intramammary artery anastomosis. Methods A chronic, stenotic coronary artery model was established in 12 of 14 Chinese experimental miniature pigs of either sex, which were randomly divided into equal control (n = 6) and experimental (n = 6) groups. In experimental animals, blood flow was reconstructed in the right coronary artery using intramammary artery. Arterialization involved dissection of right internal mammary artery from bifurcation to apex of thorax followed by end-to-side anastomosis of internal mammary artery and middle cardiac vein plus posterior descending branch of right coronary artery. Intraoperative heart rate was maintained at 110 beats/min. Graft flow assessment and echocardiography were performed when blood pressure and heart rate normalized. Results The experimental group had significantly higher mean endocardial and epicardial blood flow postoperatively than control group (mean endocardial blood flow: 0.37 vs. 0.14 ml/(g*min), p<0.001; mean epicardial blood flow: 0.29 vs. 0.22, p = 0.014). Transmural blood flow was also higher in experimental group than in control group (0.33 vs. 0.19, p<0.001); ejection fraction increased from 0.46% at baseline to 0.51% (p = 0.0038) at 6 hours postoperatively, and mean blood flow of internal mammary artery was 44.50, perfusion index 0.73 at postoperative 6 months, 43.33 and 0.80 at 3 months. Conclusion Successful cardiac vein arterialization via intramammary artery in a porcine model suggests that this may be a viable method for reconstructing blood flow in chronic, severe coronary artery disease.
Off-pump coronary artery bypass grafting using a bilateral internal mammary artery Y graft

Cheng-Xiong Gu,Jun-Feng Yang,Hong-Chao Zhang,Hua Wei,Ling-Ke Li,

老年心脏病学杂志(英文版) , 2012,
Abstract:
The Combination of RAD001 and NVP-BEZ235 Exerts Synergistic Anticancer Activity against Non-Small Cell Lung Cancer In Vitro and In Vivo
Cheng-Xiong Xu,Yikun Li,Ping Yue,Taofeek K. Owonikoko,Suresh S. Ramalingam,Fadlo R. Khuri,Shi-Yong Sun
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0020899
Abstract: The phosphoinositide 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) signaling axis has emerged as a novel target for cancer therapy. Agents that inhibit PI3K, mTOR or both are currently under development. The mTOR allosteric inhibitor, RAD001, and the PI3K/mTOR dual kinase inhibitor, BEZ235, are examples of these agents. We were interested in developing strategies to enhance mTOR-targeted caner therapy. In this study, we found that BEZ235 alone effectively inhibited the growth of rapamycin-resistant cancer cells. Interestingly, the combination of sub-optimal concentrations of RAD001 and BEZ235 exerted synergistic inhibition of the growth of human lung cancer cells along with induction of apoptosis and G1 arrest. Furthermore, the combination was also more effective than either agent alone in inhibiting the growth of lung cancer xenografts in mice. The combination showed enhanced effects on inhibiting mTOR signaling and reducing the expression of c-Myc and cyclin D1. Taken together, our results suggest that the combination of RAD001 and BEZ235 is a novel strategy for cancer therapy.
Association of HLA-A, B, DRB1 alleles and haplotypes with HIV-1 infection in Chongqing, China
Xia Huang, Hua Ling, Wei Mao, Xianbin Ding, Quanhua Zhou, Mei Han, Fang Wang, Lei Cheng, Hongyan Xiong
BMC Infectious Diseases , 2009, DOI: 10.1186/1471-2334-9-201
Abstract: In this population-based study, we performed polymerase chain reaction analysis with sequence-specific oligonucleotide probes (PCR-SSOP) for intermediate-low-resolution HLA typing in a cohort of 549 HIV-1 infected individuals, another 2475 healthy subjects from the Han nationality in Chongqing, China, were selected as population control. We compared frequencies of HLA-A, B, DRB1 alleles, haplotypes and genotypes between the two groups, and analyzed their association with HIV-1 susceptibility or resistance.The genetic profile of HLA (A, B, DRB1) alleles of HIV-1 infected individuals from Chongqing Han of China was obtained. Several alleles of HLA-B such as B*46 (P = 0.001, OR = 1.38, 95%CI = 1.13-1.68), B*1501G(B62) (P = 0.013, OR = 1.42, 95%CI = 1.08-1.88), B*67 (P = 0.022, OR = 2.76, 95%CI = 1.16-6.57), B*37 (P = 0.014, OR = 1.93, 95%CI = 1.14-3.28) and B*52 (P = 0.038, OR = 1.64, 95%CI = 1.03-2.61) were observed to have association with susceptibility to HIV-1 infection in this population. In addition, the haplotype analysis revealed that A*11-B*46, A*24-B*54 and A*01-B*37 for 2-locus, and A*11-B*46-DRB1*09, A*02-B*46-DRB1*08, A*11-B*4001G-DRB1*15, A*02-B*4001G-DRB1*04, A*11-B*46-DRB1*08 and A*02-B*4001G-DRB1*12 for 3-locus had significantly overrepresented in HIV-1 infected individuals, whereas A*11-B*1502G, A*11-B*1502G-DRB1*12 and A*33-B*58-DRB1*13 were underrepresented. However, the low-resolution homozygosity of HLA-A, B, DRB1 loci and HLA-Bw4/Bw6 genotypes did not differ significantly between the two groups.These results may contribute to the database of HLA profiles in HIV-1 infected Chinese population, consequently, the association of certain HLA alleles with susceptibility or resistance to HIV-1 infection would provide with clues in choosing proper preventive strategies against HIV-1 infection and developing effective HIV-1 vaccines in Chinese population, especially for those in southwest China.The HIV/AIDS epidemic remains a significant global problem be
Application of MOS-1b/MESSR Data in Monitoring Flood Disaster
基于MOS-1b/MESSR的洪灾遥感监测

MAO Xian-cheng,XIONG Liang-hui,Isao Takashima,
毛先成
,熊靓辉,高岛·勋

遥感技术与应用 , 2007,
Abstract: Remote sensing technique is playing an important role in flood monitoring and assessing system. This paper takes Dongting Lake district as the studying area and utilizes multi-temporal MOS-1b/MESSR data as remote sensing info source. By the combination operation and ratio transform processing and the image, spectrum and histogram comparison of the MESSR image data of all bands for the flooding season and dry season with the ERDAS IMAGINE system, a classification model (B1+B2)/(B3+B4)>t is established, in which model can be used to acquire the spatial distributing information of water bodies.Meanwhile a water depth index (WDI ) model WDI=B1/B2 is derived and built and then a model for detecting the depth of waterbody based on the non-linear recursive analysis. By the overlay analysis of the classification thematic images based on themodel for extracting flood information, the flooding area and distributing information is acquired, which can offer an important scientific basis for flood fighting and prevention in time.
CoMFA, CoMSIA and Eigenvalue Analysis on Dibenzodioxepinone and Dibenzodioxocinone Derivatives as Cholesteryl Ester Transfer Protein Inhibitors
Xu-qiong Xiong,Dong-mei Zhao,Peng-fei Bu,Yang Liu,Jin-hong Ren,Jian Wang,Mao-sheng Cheng
Molecules , 2008, DOI: 10.3390/molecules13081822
Abstract: CoMFA, CoMSIA and eigenvalue analysis (EVA) were performed to study the structural features of 61 diverse dibenzodioxepinone and dibenzodioxocinone analogues to probe cholesteryl ester transfer protein (CETP) inhibitory activity. Three methods yielded statistically significant models upon assessment of cross-validation, bootstrapping, and progressive scrambling. This was further validated by an external set of 13 derivatives. Our results demonstrate that three models have a good interpolation as well as extrapolation. The hydrophobic features were confirmed to contribute significantly to inhibitor potencies, while a pre-oriented hydrogen bond provided by the hydroxyl group at the 3-position indicated a good correlation with previous SAR, and a hydrogen bond acceptor may play a crucial role in CETP inhibition. These derived models may help us to gain a deeper understanding of the binding interaction of these lactone-based compounds and aid in the design of new potent compounds against CETP.
Analysis of the correlation between γ-ray and radio emissions from γ-ray loud Blazar using the discrete correlation function
用离散相关函数方法分析Blazar天体的γ射线和射电辐射的相关性

Cheng Yong,Zhang Xiong,Wu Lin,Mao Wei-Ming,You Li-Sha,
程 勇
,张 雄,伍 林,毛慰明,尤莉莎

物理学报 , 2006,
Abstract: 收集了119颗有γ射线噪的Blazar天体样品(97个平谱射电类星体和22个BL Lac天体),用离散相关函数(DCF)方法分析了1GeV γ射线辐射流量(最大值、最小值和平均值)与8.4GHz射电辐射流量之间的相关性.获得的主要结果为:在119个Blazar天体和97个平谱射电类星体中,γ射线辐射流量的最大值以及平均值和射电辐射流量之间有相关性;而γ射线辐射流量的最小值和射电辐射流量之间没有相关性.本文结果表明,γ射线和射电辐射都来自喷流,γ射线很可能产生于同步自康普顿(SSC)过程.
Context-Based Mobile User Interface  [PDF]
Mao Zheng, Sihan Cheng, Qian Xu
Journal of Computer and Communications (JCC) , 2016, DOI: 10.4236/jcc.2016.49001
Abstract: Context awareness is increasingly gaining applicability in interactive ubiquitous mobile computing systems. Each context-aware application has its own set of behaviors to react to context modifications. Hence, every software engineer needs to clearly understand the goal of the development and to categorize the context in the application. We incorporate context-based modifications into the appearance or the behavior of the interface, either at the design time or at the run time. In this paper, we present application behavior adaption to the context modification via a context-based user interface in a mobile application. We are interested in a context-based user interface in a mobile device that is automatically adapted based on the context information. We use the adaption tree, named in our methodology, to represent the adaption of mobile device user interface to various context information. The context includes the user’s domain information and dynamic environment changes. Each path in the adaption tree, from the root to the leaf, presents an adaption rule. An e-commerce application is chosen to illustrate our approach. This mobile application was developed based on the adaption tree in the Android platform. The automatic adaption to the context information has enhanced human-computer interactions.
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