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Search Results: 1 - 10 of 78216 matches for " Chen GongYing "
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Remotely Modify GIS System Based on GPRS and GPS
基于GPRS和GPS的远程电子地图修复系统

Chen GongYing,
陈红英

计算机系统应用 , 2006,
Abstract: 本系统采用将GPS信息通过GPRS的SOCKET通讯实时传递到多个GIS控制中心的电子地图显示修补系统,解决了实时绘制、动态显示、同步更新、限区定制等电子地图更新维护的瓶颈问题,可快速、高效、联网、互动地实现地理信息的更新,为通常费时费力的电子地图制作更新提供了新的切入点。
Distinct Determinants in HIV-1 Vif and Human APOBEC3 Proteins Are Required for the Suppression of Diverse Host Anti-Viral Proteins
Wenyan Zhang, Gongying Chen, Anna Maria Niewiadomska, Rongzhen Xu, Xiao-Fang Yu
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0003963
Abstract: Background APOBEC3G (A3G) and related cytidine deaminases of the APOBEC3 family of proteins are potent inhibitors of many retroviruses, including HIV-1. Formation of infectious HIV-1 requires the suppression of multiple cytidine deaminases by Vif. HIV-1 Vif suppresses various APOBEC3 proteins through the common mechanism of recruiting the Cullin5-ElonginB-ElonginC E3 ubiquitin ligase to induce target protein polyubiquitination and proteasome-mediated degradation. The domains in Vif and various APOBEC3 proteins required for APOBEC3 recognition and degradation have not been fully characterized. Methods and Findings In the present study, we have demonstrated that the regions of APOBEC3F (A3F) that are required for its HIV-1-mediated binding and degradation are distinct from those reported for A3G. We found that the C-terminal cytidine deaminase domain (C-CDD) of A3F alone is sufficient for its interaction with HIV-1 Vif and its Vif-mediated degradation. We also observed that the domains of HIV-1 Vif that are uniquely required for its functional interaction with full-length A3F are also required for the degradation of the C-CDD of A3F; in contrast, those Vif domains that are uniquely required for functional interaction with A3G are not required for the degradation of the C-CDD of A3F. Interestingly, the HIV-1 Vif domains required for the degradation of A3F are also required for the degradation of A3C and A3DE. On the other hand, the Vif domains uniquely required for the degradation of A3G are dispensable for the degradation of cytidine deaminases A3C and A3DE. Conclusions Our data suggest that distinct regions of A3F and A3G are targeted by HIV-1 Vif molecules. However, HIV-1 Vif suppresses A3F, A3C, and A3DE through similar recognition determinants, which are conserved among Vif molecules from diverse HIV-1 strains. Mapping these determinants may be useful for the design of novel anti-HIV inhibitors.
The Effect of Initial Oxidation on Long-Term Oxidation of NiCoCrAlY Alloy  [PDF]
Chao Zhu, Xiaoyu Wu, Yuan Wu, Gongying Liang
Engineering (ENG) , 2010, DOI: 10.4236/eng.2010.28077
Abstract: The initial oxidation behavior of Ni-6.5Co-17.8Cr-3.7Al-0.5Y alloy is investigated at 800°C-1000°C. X-ray diffraction results show that the dominant Cr2O3 phase and secondary α-Al2O3 and NiO phases are observed on the surface of samples at all initial stages (oxidized for 16 hours). YAlO3 and θ-Al2O3 can only be detected at low temperature (800°C) while the spinel NiCr2O4 is only observed at 900°C and 1000°C. Though the growth rates of α-Al2O3 and Cr2O3 are comparable at 900°C, the former becomes much lower than the latter when the temperature changes to 1000°C. Scanning electron microscopy (SEM) images show that the α-Al2O3 grows from some irregular ditches in the chromia scale at 900°C. However, cracking and spalling are more serious at 1000°C without α-Al2O3-grown-ditches, which is in accordance with the growth rates of these oxides at different temperatures. The cracking can be explained by the results of Raman determination which indicate that the stress on the surface of specimen oxidized at 1000°C is higher than that at 900°C. Owing to this condition, a preoxidation treatment on the NiCoCrAlY alloy for 16 hours is prepared at 900°C, and then thermal cycling oxidation test is conducted at 1000°C for 200 hours. The result indicates that the initial preoxidation treatment at 900°C improves the oxidation resistance of alloy at 1000°C.
THERMAL ANALYSIS STUDY OF Fe-Cr-Mn HEAT RESISTANT ALLOY
LIANG Gongying XING Jiandong Xi'an Jiaotong University,Xi'an,China Lecturer,
LIANG Gongying XING Jiandong Xi''''an Jiaotong University
,Xi''''an,China Lecturer

金属学报(英文版) , 1992,
Abstract: Thermal analysis has been adopted to determine the liquidus and eutectic temperature of Fe-20%Cr-Mn alloy over range of Mn and C contents.Using regression analysis,the par- tial quasi-binary phase diagrams of Fe-Mn alloy(solidification range)have been con- structed.And the effect of Mn content on liquidus and eutectic temperature was discussed.
A THERMAL ANALYSIS STUDY OF Fe-Cr-Mn HEAT RESISTANT ALLOY
Fe—Cr—Mn耐热合金的热分析研究

LIANG Gongying,XING Jiandong Xi''''an Jiaotong University,
梁工英
,邢建东

金属学报 , 1991,
Abstract: 用热分析法测定了不同含Mn,C量的Fe-20%Cr-Mn合金的液相线温度和共晶转变温度,通过回归分析得到不同含C量的Fe-Mn准二元相图(凝固区间部分),分析了含Mn量对Fe-20%Cr-Mn合金液相线和共晶转变温度的影响。
LASER REMELTED Ni-Cr-B-Si COATING ON Al-Si ALLOY
Al—Si合金等离子涂层Ni—Cr—B—Si的激光重熔

LIANG Gongying,LI Chenglao,SU Junyi,
梁工英
,李成劳,苏俊义

金属学报 , 1997,
Abstract: 利用5kW CO2激光器重熔Al-Si合金表面的Ni-Cr-B-Si等离子喷涂层。SEM和TEM分析结果表明,激光熔层内晶化区和非晶化区共存,在后续熔区的传热作用和周围结晶潜热作用下,有部分非晶晶化为Ni3Al纳米晶(2-5nm),其中一些逐渐长大成为细小的粒状晶。未晶化区硬度极高(HV=1235),是原等离子喷涂层硬度的4倍。
Childhood Sexual Abuse and the Development of Recurrent Major Depression in Chinese Women
Jing Chen, Yiyun Cai, Enzhao Cong, Ying Liu, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Zhen Zhang, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S. Kendler, Shenxun Shi, Jonathan Flint
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0087569
Abstract: Background Our prior study in Han Chinese women has shown that women with a history of childhood sexual abuse (CSA) are at increased risk for developing major depression (MD). Would this relationship be found in our whole data set? Method Three levels of CSA (non-genital, genital, and intercourse) were assessed by self-report in two groups of Han Chinese women: 6017 clinically ascertained with recurrent MD and 5983 matched controls. Diagnostic and other risk factor information was assessed at personal interview. Odds ratios (ORs) were calculated by logistic regression. Results We confirmed earlier results by replicating prior analyses in 3,950 new recurrent MD cases. There were no significant differences between the two data sets. Any form of CSA was significantly associated with recurrent MD (OR 4.06, 95% confidence interval (CI) [3.19–5.24]). This association strengthened with increasing CSA severity: non-genital (OR 2.21, 95% CI 1.58–3.15), genital (OR 5.24, 95% CI 3.52–8.15) and intercourse (OR 10.65, 95% CI 5.56–23.71). Among the depressed women, those with CSA had an earlier age of onset, longer depressive episodes. Recurrent MD patients those with CSA had an increased risk for dysthymia (OR 1.60, 95%CI 1.11–2.27) and phobia (OR 1.41, 95%CI 1.09–1.80). Any form of CSA was significantly associated with suicidal ideation or attempt (OR 1.50, 95% CI 1.20–1.89) and feelings of worthlessness or guilt (OR 1.41, 95% CI 1.02–2.02). Intercourse (OR 3.47, 95%CI 1.66–8.22), use of force and threats (OR 1.95, 95%CI 1.05–3.82) and how strongly the victims were affected at the time (OR 1.39, 95%CI 1.20–1.64) were significantly associated with recurrent MD. Conclusions In Chinese women CSA is strongly associated with recurrent MD and this association increases with greater severity of CSA. Depressed women with CSA have some specific clinical traits. Some features of CSA were associated with greater likelihood of developing recurrent MD.
Suicidal Risk Factors of Recurrent Major Depression in Han Chinese Women
Yuzhang Zhu, Hongni Zhang, Shenxun Shi, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Zhen Zhang, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth Seedman Kendler, Jonathan Flint, Ying Liu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080030
Abstract: The relationship between suicidality and major depression is complex. Socio- demography, clinical features, comorbidity, clinical symptoms, and stressful life events are important factors influencing suicide in major depression, but these are not well defined. Thus, the aim of the present study was to assess the associations between the above-mentioned factors and suicide ideation, suicide plan, and suicide attempt in 6008 Han Chinese women with recurrent major depression (MD). Patients with any suicidality had significantly more MD symptoms, a significantly greater number of stressful life events, a positive family history of MD, a greater number of episodes, a significant experience of melancholia, and earlier age of onset. Comorbidity with dysthymia, generalized anxiety disorder (GAD), social phobia, and animal phobia was seen in suicidal patients. The present findings indicate that specific factors act to increase the likelihood of suicide in MD. Our results may help improve the clinical assessment of suicide risk in depressed patients, especially for women.
Clinical Features of Patients with Dysthymia in a Large Cohort of Han Chinese Women with Recurrent Major Depression
Wenqing Wu, Zhoubing Wang, Yan Wei, Guanghua Zhang, Shenxun Shi, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Ying Liu, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S. Kendler, Jonathan Flint, Zhen Zhang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0083490
Abstract: Background Dysthymia is a form of chronic mild depression that has a complex relationship with major depressive disorder (MDD). Here we investigate the role of environmental risk factors, including stressful life events and parenting style, in patients with both MDD and dysthymia. We ask whether these risk factors act in the same way in MDD with and without dysthymia. Results We examined the clinical features in 5,950 Han Chinese women with MDD between 30–60 years of age across China. We confirmed earlier results by replicating prior analyses in 3,950 new MDD cases. There were no significant differences between the two data sets. We identified sixteen stressful life events that significantly increase the risk of dysthymia, given the presence of MDD. Low parental warmth, from either mother or father, increases the risk of dysthymia. Highly threatening but short-lived threats (such as rape) are more specific for MDD than dysthymia. While for MDD more severe life events show the largest odds ratio versus controls, this was not seen for cases of MDD with or without dysthymia. Conclusions There are increased rates of stressful life events in MDD with dysthymia, but the impact of life events on susceptibility to dysthymia with MDD differs from that seen for MDD alone. The pattern does not fit a simple dose-response relationship, suggesting that there are moderating factors involved in the relationship between environmental precipitants and the onset of dysthymia. It is possible that severe life events in childhood events index a general susceptibility to chronic depression, rather than acting specifically as risk factors for dysthymia.
Associations of Educational Attainment, Occupation, Social Class and Major Depressive Disorder among Han Chinese Women
Jianguo Shi, Yan Zhang, Feihu Liu, Yajuan Li, Junhui Wang, Jonathan Flint, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Shenxun Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Zhen Zhang, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S. Kendler
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0086674
Abstract: Background The prevalence of major depressive disorder (MDD) is higher in those with low levels of educational attainment, the unemployed and those with low social status. However the extent to which these factors cause MDD is unclear. Most of the available data comes from studies in developed countries, and these findings may not extrapolate to developing countries. Examining the relationship between MDD and socio economic status in China is likely to add to the debate because of the radical economic and social changes occurring in China over the last 30 years. Principal findings We report results from 3,639 Chinese women with recurrent MDD and 3,800 controls. Highly significant odds ratios (ORs) were observed between MDD and full time employment (OR = 0.36, 95% CI = 0.25–0.46, logP = 78), social status (OR = 0.83, 95% CI = 0.77–0.87, logP = 13.3) and education attainment (OR = 0.90, 95% CI = 0.86–0.90, logP = 6.8). We found a monotonic relationship between increasing age and increasing levels of educational attainment. Those with only primary school education have significantly more episodes of MDD (mean 6.5, P-value = 0.009) and have a clinically more severe disorder, while those with higher educational attainment are likely to manifest more comorbid anxiety disorders. Conclusions In China lower socioeconomic position is associated with increased rates of MDD, as it is elsewhere in the world. Significantly more episodes of MDD occur among those with lower educational attainment (rather than longer episodes of disease), consistent with the hypothesis that the lower socioeconomic position increases the likelihood of developing MDD. The phenomenology of MDD varies according to the degree of educational attainment: higher educational attainment not only appears to protect against MDD but alters its presentation, to a more anxious phenotype.
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