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Search Results: 1 - 10 of 1333 matches for " Charlotte Strandhave "
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Haptoglobin Genotype and Risk Markers of Cardiovascular Disease in Patients with Chronic Kidney Disease
Charlotte Strandhave,My Svensson,Henrik Krarup,Jeppe Hagstrup Christensen
International Journal of Nephrology , 2013, DOI: 10.1155/2013/650847
Abstract:
Haptoglobin Genotype and Risk Markers of Cardiovascular Disease in Patients with Chronic Kidney Disease
Charlotte Strandhave,My Svensson,Henrik Krarup,Jeppe Hagstrup Christensen
International Journal of Nephrology , 2013, DOI: 10.1155/2013/650847
Abstract: Sudden cardiac death and atherosclerosis have a major impact on cardiovascular mortality in chronic kidney disease (CKD). Inflammation with elevated high-sensitive C-reactive protein (hs-CRP) is involved in both sudden cardiac death and atherosclerosis, and decreased heart rate variability (HRV) is a predictor of both sudden cardiac death and atherosclerosis. Haptoglobin (Hp) is characterised by three genotypes (1-1, 2-1, and 2-2) with different antioxidant abilities. The aim was to examine whether HRV and hs-CRP were associated with Hp genotype in CKD patients. Fifty-six patients with CKD stage 2–5 were included. Hp genotype was determined by high-performance liquid chromatography. HRV was analysed from the 24 h Holter recordings. Hs-CRP was measured using an immunoturbidimetric assay. The results show that the HRV indices SDNN and SDANN were significantly lower in the Hp 2-2 patients ( and 0.04, resp.). In an adjusted linear regression model, Hp 2-2 was associated with both SDNN ( ) and SDANN ( ). Hs-CRP was higher in the Hp 2-2 patients ( ). In an adjusted linear regression model, the association between Hp 2-2 and hs-CRP remained significant ( ). In conclusion, a negative association was observed between Hp 2-2 and HRV, and Hp 2-2 was positively associated with hs-CRP in CKD patients. 1. Introduction Cardiovascular disease (CVD) including sudden cardiac death (SCD) [1] is a major cause of mortality in chronic kidney disease (CKD) [2]. Apart from left ventricular dysfunction [1], unique factors such as autonomic imbalance and inflammation contribute to the high incidence of SCD in CKD [3]. Traditional risk factors for atherosclerosis [4], such as hypertension and dyslipidaemia, can to some extent explain the increased risk of atherosclerosis in CKD [5]. However, nontraditional risk factors like oxidative stress and inflammation may also be of importance [6]. Heart rate variability (HRV) is a reliable, noninvasive measurement of autonomic tone of the heart [7]. A reduction in HRV reflects an autonomic imbalance towards decreased vagal tone and subsequent sympathetic overactivity [3]. Decreased HRV is a predictor of SCD in patients with CKD [8]. Furthermore, attenuated HRV is associated with atherosclerosis in CKD [9]. Chronic, low-grade inflammation is involved in the development of both SCD [10] and atherosclerosis [11]. The most extensively examined marker of inflammation is high-sensitive C-reactive protein (hs-CRP), which is a predictor of cardiovascular mortality in different populations [12, 13] including patients with CKD [14]. Hs-CRP may even
Qualitative Research on Emergency Medicine Physicians: A Literature Review  [PDF]
Charlotte Paltved, Peter Musaeus
International Journal of Clinical Medicine (IJCM) , 2012, DOI: 10.4236/ijcm.2012.37A136
Abstract:

Aim: This study aims to review the qualitative research studying Emergency Medicine (EM) physicians in Emergency Departments (ED). Background: Qualitative research aims to study complex social phenomena by other means than quantification often through verbal or observational investigation. EM is a highly complex medical and social environment that has been investigated through qualitative methodologies. A literature review is needed to show what qualitative studies illuminate about EM and why this work is important to develop EM as a complex organizational and communicative practice. Methods: Electronic databases of English peer-reviewed articles were searched from 1971 to 2012 using Medline through PubMed and PsychINFO. This search was supplemented with hand-searches of Academic Emergency Medicine and Emergency Medicine Journal from 1999 to 2012 and cross references were reviewed. The key words used were emergency medicine, qualitative, ethnography, observation, interview, video, anthropology, simulation, and simulation-based. Results: 820 papers were identified and 46 studies were included in this review. This literature review found that the reviewed qualitative studies on EM physicians were designed using the following strategies of inquiry: Ethnography, mixed methods, action research, grounded theory, phenomenology, content analysis, discourse analysis, and critical incident analysis. The reviewed studies were categorized into four main themes: Education and training, communication, professional roles, and organizational factors, and into 12 sub-themes. Conclusion: The strength of qualitative research is its ability to grasp and operationalize complex relations within EM. Although qualitative research methodologies have gained in rigor in recent years and few researchers would question their value in studying complex medical and social phenomena, rigorous design in qualitative studies is needed. Qualitative research studies that stick with one strategy of inquiry that they follow closely are likely to yield more valid studies.

Measuring changes in self-concept: a qualitative evaluation of outcome questionnaires in people having acupuncture for their chronic health problems
Charlotte Paterson
BMC Complementary and Alternative Medicine , 2006, DOI: 10.1186/1472-6882-6-7
Abstract: A literature search was followed by an evaluation of three questionnaires: The Wellbeing Questionnaire W-BQ12, the Patient Enablement Instrument (PEI), and the Arizona Integrative Outcome Scale (AIOS). A convenience sample of 23 people completed the questionnaires on two occasions and were interviewed about their experience and their questionnaire responses. All acupuncturists were interviewed.Changes in self-concept were common and emerged over time. The three questionnaires had different strengths and weaknesses in relation to measuring changes in self-concept. The generic AIOS had face validity and was sensitive to changes in self-concept over time, but it lacked specificity. The PEI was sensitive and specific in measuring these changes but had lower acceptability. The sensitivity of the W-BQ12 was affected by initial high scores (ceiling effect) and a shorter timescale but was acceptable and is suitable for repeated administration. The PEI and W-BQ12 questionnaires worked well in combination.Changes in self-concept are important outcomes of complex interventions for people with long-term illness and their measurement requires carefully evaluated tools and long-term follow-up. The literature review and the analysis of the strengths and weaknesses of the questionnaires is a resource for other researchers. The W-BQ12 and the PEI both proved useful for this population and a larger quantitative study is planned.Relevant, comprehensive, and valid outcome measures are a pre-requisite for all experimental and observational evaluations of healthcare interventions. The choice of outcome measures is especially problematic in evaluating complex interventions, interventions for people with long-term health problems, and interventions that aim to bring about a wide range of treatment effects and behaviour change. In these situations it has been suggested that a staged process of enquiry should be instituted, and that qualitative and theoretical work may play an important part
La primera relación sexual en Venezuela
Letellier,Charlotte;
Opción , 2007,
Abstract: the universality of interdictions and the almost similarity from one society to another suggest that cultural codes are sexually distinct based on roles and functions of man and woman. not a single society has known a fixed sexual morality which on the contrary seems to change regarding historical circumstances. every individual is subject to his or her culture which he or her auto reproduces without realizing it. from the first steps into sexuality to an adult and active sexual life, individuals react regarding their specific roles and social frames. sexual initiation is much ritualized in venezuela and contains family?s honour as well as the social status of the individual. in france, it?s personal and private and only concerns the individual. despite all this, the first sexual experience is an obliged passage experienced as a love act or as an initiation act. we shall see that depending on gender and social class, the conditions of the first sexual experience?s advent follow different schemes.
Evaluation of a number skills development programme
Charlotte Pietersen
South African Journal of Education , 2006,
Abstract: A pre-test post-test correlated groups design was used to evaluate the effectiveness of the Shuttleworth/Rotary Number Skills Development Programme to enhance the numeracy of Grade 2 learners (N = 1 69) from five primary schools (a private school, a school of auditory impaired learners, and three rural schools). An un structured questionnaire was employed to obtain teachers' views about the program (n = 5). The findings of the study showed that the programme was effective in developing the numeracy of the total sample, and of learners from the different types of schools. It was concluded that the use of concrete educational material should be central in the teaching of number skills in Grade 2. The teachers also indicated that the programme was beneficial to learners and to themselves. However differences in the improvement of the numeracy sc ores of the five c lasses w ere found (possibly du e to difference in instructional quality). Therefore, it is recommended that teachers should be trained in the use of educational equipment and also to create an optimal learning environment. Further research, with more representative samples, is required to verify the effectiveness of (and broaden) the application of the programme, and to explore teacher-related variables that could limit numeracy development in learners. South African Journal of Education Vol. 26(3) 2006: 413–426
Nova Scotia Library Association (NSLA) News
Charlotte Janes
Partnership : the Canadian Journal of Library and Information Practice and Research , 2006,
Abstract:
Avant-gardes et arrière-gardes artistiques au temps de l’Exposition franco-britannique
Charlotte Ribeyrol
Synergies Royaume-Uni et Irlande , 2009,
Abstract: à la lecture du catalogue d’Isidore Spielmann, les choix esthétiquesdu British Committee chargé de l’élaboration de la Fine Arts Section del’Exposition franco-britannique de 1908, surprennent par leur parti pris de nonmodernité. Les peintures académiques, mythologiques ou de paysages classiques prédominent largement tant dans la partie anglaise que dans la section consacrée à la France. Pour le British Committee, l’objectif est clairement posé : il s’agitde redorer le blason de l’art anglais qui, au cours des grandes expositions qui ont jalonné le XIXe siècle depuis la Great Exhibition de 1851, a toujours souffert de la comparaison avec l’art fran ais, grand favori du public. Ce décalage patent avec les expérimentations abstraites et modernistes de la période peut s’expliquer par la volonté des représentants de l’art anglais d’en imposer avec une histoire fameuse – de William Hogarth à Edward Poynter – sans s’attarder sur des productions plus subversives et plus contestées. De fait, l’exposition même des uvres adopte la muséographie classique de la Royal Academy.Des peintres autrefois jugés indécents, sulfureux, tels qu’Edward Burne-Jones ou Dante Gabriel Rossetti font l’objet d’une reconnaissance mais aussi d’une relecture académique tardive ou posthume. Cet article tentera d’interroger d’une part la tentative d’ académisation des avant-gardes de la fin du XIXe siècle et d’autre part le rapport souvent paradoxal des nouveaux courants artistiques du début du XXe siècle avec la tradition picturale classique .
Nova Scotia Library Association (NSLA) News
Charlotte Janes
Partnership : the Canadian Journal of Library and Information Practice and Research , 2006,
Abstract:
Die Entstehung eines politischen Mythos in Athen. Von der Tyrannis zur Demokratie
Charlotte Schubert
Behemoth : a Journal on Civilisation , 2010,
Abstract: The choice of the heroes Harmodius and Aristogeiton as the symbol of a founding myth – unencumbered by previous conflicts after the victory of Salamis in the Persian wars – represents the belief of the Athenians that tyranny was finally defeated. The Athenians declared Harmodius and Aristeigeiton as founders and ascribed them the merit of having introduced the new political order rather than Cleisthenes, the reformer, who had introduced it and who was, together with the Spartan king Cleomenes, largely responsible for the overthrow of tyranny some years before the Persian wars. After Salamis this phase was completed, the new founding fathers Harmodius and Aristogeiton were successfully established and with them the conflicts of previous decades were covered over, or in the strict sense of the word, rendered invisible – in the truest sense this is then one of the most spectacular examples of counterfactual history.
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