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Search Results: 1 - 10 of 144967 matches for " Carroll B "
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Evolution at Two Levels: On Genes and Form
Sean B. Carroll
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0030245
Abstract:
Evolution at two levels: on genes and form.
Carroll Sean B
PLOS Biology , 2005,
Abstract:
Evolution at Two Levels: On Genes and Form
Sean B Carroll
PLOS Biology , 2005, DOI: 10.1371/journal.pbio.0030245
Abstract:
Persistent Lymphadenopathy due to IgG4-Related Disease
Benjamin Smith,Matthew B. Carroll
Case Reports in Immunology , 2012, DOI: 10.1155/2012/158208
Abstract: A 28-year-old healthy female presented to her primary care physician with lymphadenopathy, fatigue, malaise, and night sweats. Symptoms persisted despite conservative treatment and eventually the patient underwent multiple lymph node resections and a bone marrow biopsy before a diagnosis of IgG4-related disease (IgG4-RD) was made. IgG4-RD is a relatively new disorder first histopathologically recognized within the last decade. As the disease can affect a single organ or multiple organs, symptoms can vary greatly among patients. With symptoms ranging from mild, such as lower extremity edema, to severe, such as spinal cord compression, IgG4-RD must be considered in appropriate patients. Diagnostic criteria have been proposed based on organ involvement, serum IgG4 levels, and histopathological criteria. Diagnosis can be difficult to make with many studies suggesting different values for diagnostic criteria, such as the level of tissue IgG4
Bushes in the Tree of Life
Antonis Rokas,Sean B. Carroll
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0040352
Abstract:
Bushes in the Tree of Life
Antonis Rokas ,Sean B Carroll
PLOS Biology , 2006, DOI: 10.1371/journal.pbio.0040352
Abstract:
Persistent Lymphadenopathy due to IgG4-Related Disease
Benjamin Smith,Matthew B. Carroll
Case Reports in Immunology , 2012, DOI: 10.1155/2012/158208
Abstract: A 28-year-old healthy female presented to her primary care physician with lymphadenopathy, fatigue, malaise, and night sweats. Symptoms persisted despite conservative treatment and eventually the patient underwent multiple lymph node resections and a bone marrow biopsy before a diagnosis of IgG4-related disease (IgG4-RD) was made. IgG4-RD is a relatively new disorder first histopathologically recognized within the last decade. As the disease can affect a single organ or multiple organs, symptoms can vary greatly among patients. With symptoms ranging from mild, such as lower extremity edema, to severe, such as spinal cord compression, IgG4-RD must be considered in appropriate patients. Diagnostic criteria have been proposed based on organ involvement, serum IgG4 levels, and histopathological criteria. Diagnosis can be difficult to make with many studies suggesting different values for diagnostic criteria, such as the level of tissue IgG4+/IgG+ cell ratio to delineate IgG4-RD. Treatment consists of high dose glucocorticoids as a first line therapy with some patients choosing instead to simply undergo observation. This case illustrates the difficulty in diagnosis and the need for increased awareness among medical professionals. 1. Introduction IgG4-RD is a relatively newly classified condition with unifying histopathologic features recognized only since the early 2000s [1]. The disorder is thought to mainly affect middle-aged to elderly men with a median age of onset of 58 years old [2, 3]. Exact incidence and prevalence are difficult to determine as many cases most likely go undiagnosed with limited awareness currently amongst medical professionals. Clinical findings vary by the organ system involved but many times are associated with tissue swelling or enlargement [1]. Due to the variety of clinical presentations, diagnosis can be delayed months to years and result in unnecessary tests and procedures. 2. Case Presentation A 28-year-old female with no significant past medical history presented to her primary care physician with lymphadenopathy, night sweats, fatigue, and malaise. She was treated empirically and partially responded to a short course of glucocorticoids and an antibiotic. When initial laboratory workup was unrevealing for an obvious etiology and symptoms persisted, computed tomography (CT) of the neck and chest with contrast was performed that showed diffuse adenopathy (Figure 1) and hepatosplenomegaly. The patient was referred for lymph node resection that initially revealed only nonspecific B cell proliferation and did not support a
SAVING THE PITCHER
Will Carroll
Journal of Sports Science and Medicine , 2004,
Abstract: This hardcover book introduces and updates the average fan as well as coaches, trainers, pitchers, biomechanical experts and such people to the theory and practice of analyzing the mechanics of pitching and preventing the possible injuries as a result. The book addresses different aspects of pitcher conditioning, mechanics, workload, abuse and avoiding injury. It also brings some controversial ideas into the world of baseball.
Primordial Magnetic Fields that Last?
Sean M. Carroll,George B. Field
Physics , 1998,
Abstract: The magnetic fields we observe in galaxies today may have their origins in the very early universe. While a number of mechanisms have been proposed which lead to an appreciable field amplitude at early times, the subsequent evolution of the field is of crucial importance, especially whether the correlation length of the field can grow as large as the size of a protogalaxy. This talk is a report on work in progress, in which we consider the fate of one specific primordial field scenario, driven by pseudoscalar effects near the electroweak phase transition. We argue that such a scenario has a number of attractive features, although it is still uncertain whether a field of appropriate size can survive until late times.
Consequences of Propagating Torsion in Connection-Dynamic Theories of Gravity
Sean M. Carroll,George B. Field
Physics , 1994, DOI: 10.1103/PhysRevD.50.3867
Abstract: We discuss the possibility of constraining theories of gravity in which the connection is a fundamental variable by searching for observational consequences of the torsion degrees of freedom. In a wide class of models, the only modes of the torsion tensor which interact with matter are either a massive scalar or a massive spin-1 boson. Focusing on the scalar version, we study constraints on the two-dimensional parameter space characterizing the theory. For reasonable choices of these parameters the torsion decays quickly into matter fields, and no long-range fields are generated which could be discovered by ground-based or astrophysical experiments.
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